Title: TOP Family-Friendly Hotels in Northeast Missouri, MO for 2025 - Northeast Missouri Family Welcoming Hotels | Expedia.co.uk [Northeast Missouri Travel Guide](https://expedia.co.uk/Northeast-Missouri.dx6058818)[Hotels in Northeast Missouri](https://expedia.co.uk/Northeast-Missouri-Hotels.d6058818.Travel-Guide-Hotels)[Holiday Rentals in Northeast Missouri](https://expedia.co.uk/Northeast-Missouri-Holiday-Rentals.d6058818.Travel-Guide-HolidayRentals)[Flights to Northeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Northeast-Missouri.d6058818.Travel-Guide-Flights)[Things to do in Northeast Missouri](https://expedia.co.uk/Things-To-Do-In-Northeast-Missouri.d6058818.Travel-Guide-Activities)[Northeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Northeast-Missouri.d6058818.Car-Hire-Guide)[Northeast Missouri Holidays](https://expedia.co.uk/Northeast-Missouri.d6058818.Holidays-City-Breaks) ![St. Louis showing interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21573-Saint-Louis.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Family-Friendly Hotels in Northeast Missouri, MO ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Northeast Missouri Family-Friendly Hotels Tonight [21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058818&startDate=2025-09-21&endDate=2025-09-22&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Sept - 23 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058818&startDate=2025-09-22&endDate=2025-09-23&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058818&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058818&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Northeast Missouri Family-Friendly Hotels ![Interior](https://images.trvl-media.com/lodging/1000000/20000/12500/12448/f2c92049.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12500/12448/065ab803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12448/8d4c7263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/1000000/20000/12500/12448/75ba0228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St. Louis Lindbergh Boulevard St. Louis 6.6/10 (1005) "The Pool, and things for the kids to do was great." [](https://www.expedia.co.uk/St-Louis-Hotels-Days-Inn-By-Wyndham-St-Louis-Lindbergh-Boulevard.h12448.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/0bb9dbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Refrigerator & Microwave (2 Rooms, Sofabed) | 1 bedroom, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/94d57bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/a0730242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/d555c816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Near Union Station Downtown West 8.8/10 Excellent (1634) "Beautiful stay also bed is very comfortable good food as well " £85 includes taxes & fees 1 Oct - 2 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Games room](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/cdb8f3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool, open 10:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/fd2b191b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/550bec82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/13e26dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clayton Plaza Hotel & Extended Stay Clayton 8.8/10 Excellent (2946) "Its a great place to stay" £85 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/690000/687300/687285/4e3e4d9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/690000/687300/687285/33908712.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Governor's) | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/690000/687300/687285/b021e551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/690000/687300/687285/112cd9eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hotel St. Louis Downtown City Center MO Downtown West 6.6/10 (1000) "Always love staying at oyo" [](https://www.expedia.co.uk/St-Louis-Hotels-OYO-Hotel-St-Louis-Downtown-City-Center-MO.h687285.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/0467986d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/a847bb13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/1dea3ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Union Station Downtown West 9.4/10 Exceptional (1252) " Love staying here!" £105 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/8b38b72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/aeacc45e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/cca43ba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1430000/1427900/1427801/3a42e755.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites St. Louis at Forest Park Dogtown 9.4/10 Exceptional (1006) "Great place and will return " £118 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Suites-St-Louis-At-Forest-Park.h1427801.Hotel-Information) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/d7f7c2c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/0b60b4dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/2857d67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/585939b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place St. Louis/Chesterfield Chesterfield 9.6/10 Exceptional (1008) "Great place to stay" £102 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/St-Louis-Hotels-Hyatt-Place-St-LouisChesterfield.h6583788.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/19000000/18980000/18973600/18973501/7302bcb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18980000/18973600/18973501/793a998f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/19000000/18980000/18973600/18973501/2314cffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/19000000/18980000/18973600/18973501/8bd002c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Authentic Log cabin with something for everyone! Marthasville 9.6/10 Exceptional (370) "As always, the cabin did not disappoint! This place is absolutely beautiful and relaxing! Thank you so much for providing an amazing spot for a enjoyable get away. " [](https://www.expedia.co.uk/Washington-Hotels-Authentic-Log-Cabin-With-Something-For-Everyone.h18973501.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/9000000/8360000/8354200/8354160/b3f14469.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/9000000/8360000/8354200/8354160/d802f661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/9000000/8360000/8354200/8354160/22abdb46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8360000/8354200/8354160/b4b6235c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Brentwood Brentwood 9.6/10 Exceptional (1009) "The hotel staff was amazing. " £116 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Brentwood.h8354160.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d41360b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/f0151514.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d86dad87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/4e0535c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton St. Louis Downtown Downtown St. Louis 8.8/10 Excellent (1229) "Had a great stay…will stay again " £103 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-05&endDate=2025-10-06®ionId=6058818&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Northeast Missouri Hotel Reviews ![The Cheshire](//images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de_y.jpg) ### The Cheshire 10/10 Excellent "Beautiful hotel, lovely furnishings in rooms and lobby. Staff was warm, welcoming, and attentive." [](https://expedia.co.uk/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](//images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "Breakfast was great. Rooms super clean and plenty of parking." [](https://expedia.co.uk/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Sonesta ES Suites St. Louis - Chesterfield](//images.trvl-media.com/lodging/1000000/10000/500/422/a42ce99e_y.jpg) ### Sonesta ES Suites St. Louis - Chesterfield 10/10 Excellent "Best breakfast options" [](https://expedia.co.uk/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information) ![Renaissance St. Louis Airport Hotel](//images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1_y.jpg) ### Renaissance St. Louis Airport Hotel 10/10 Excellent "!" [](https://expedia.co.uk/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) ![DoubleTree by Hilton St. Louis Forest Park](//images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/3f93ad2e_y.jpg) ### DoubleTree by Hilton St. Louis Forest Park 10/10 Excellent "The staff was impeccable. Clean rooms, soft pillow, great bed, clean. Then petty was the front desk supervisor and she was awesome. She text me every day asking how I stay was and if I had a question, she would answer it. Love the cookies!" [](https://expedia.co.uk/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](//images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 10/10 Excellent "See Busch Stadium, the old architecture around the city and the Gateway Arch" [](https://expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Hollywood Casino & Hotel St. Louis](//images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg) ### Hollywood Casino & Hotel St. Louis 10/10 Excellent "Great places to jo" [](https://expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) ![Drury Inn & Suites St. Louis Union Station](//images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4_y.jpg) ### Drury Inn & Suites St. Louis Union Station 10/10 Excellent "The historic building is beautiful and the clerk was so friendly and helpful " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Marriott St. Louis Grand](//images.trvl-media.com/lodging/1000000/910000/904800/904712/4c313173_y.jpg) ### Marriott St. Louis Grand 10/10 Excellent "Very good" [](https://expedia.co.uk/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information) ## Explore a world of travel with Expedia - 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