A large eye sculpture in a park surrounded by trees.

Find Family-Friendly Hotels in Northeast Missouri, MO

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Check availability on Northeast Missouri Family-Friendly Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Northeast Missouri family-friendly hotels

A playground with a slide, swings, and a climbing structure.
An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.
A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.
A hotel lobby with a reception desk, seating area, and a sign for the general store.

1. Depot Inn and Suites

Depot Inn and Suites
La Plata
  • Let the kids loose at this La Plata hotel with indoor pools, playground, and game room for endless family fun.
£71
includes taxes & fees
25 Oct - 26 Oct
Depot Inn and Suites
A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.
A conference room with a long table, multiple chairs, framed artwork on the walls, and a television screen.
A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.
A fitness center with treadmills, stationary bikes, and elliptical machines.

2. Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
Kirksville
  • Family-friendly fun begins with an indoor pool adventure just a short drive from Thousand Hills State Park for outdoor exploration.
£100
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Kirksville - University Area by IHG
A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.
A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".
A modern hotel lobby with a reception desk, seating area, and large windows.
A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

3. Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
Kirksville
£69
includes taxes & fees
22 Oct - 23 Oct
Super 8 by Wyndham Kirksville-University Area
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.
A bar area with a long counter, multiple bottles, glasses, and a few chairs.
A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.
A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

4. Oak Hill Inn & Suites

Oak Hill Inn & Suites
Canton
£81
includes taxes & fees
21 Nov - 22 Nov
Oak Hill Inn & Suites
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.
A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

5. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
  • Family escape with an indoor pool and spacious rooms where kids splash while parents relax at the poolside bar and sun loungers.
£66
includes taxes & fees
15 Nov - 16 Nov
Quality Inn & Suites Hannibal West
A stainless steel ice dispenser with a blue button labeled 'PUSH FOR ICE' in a kitchen setting.
A white shower enclosure with a showerhead, a curtain, and a metal grab bar.
A kitchen counter with fruits, a blender, and a refrigerator with a game display.
A reception area with a counter, a trash bin, and a seating area with chairs.

6. Travelier Motel

Travelier Motel
Macon
£62
includes taxes & fees
21 Nov - 22 Nov
Travelier Motel
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.
A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

7. Best Western On The River

Best Western On The River
Hannibal
  • Family-friendly riverside hotel offers kids' paradise with indoor and outdoor pools, hot tub, and nearby fun park adventures.
£95
includes taxes & fees
25 Oct - 26 Oct
Best Western On The River
A modern hotel lobby with multiple seating areas, including a bar and dining tables.
A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.
Lobby
An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.

8. Hampton Inn Kirksville

Hampton Inn Kirksville
Kirksville
£104
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Kirksville
A hotel with a swimming pool, outdoor seating, and a sign for 'Pinemark Inn Suites & Events'.
An outdoor seating area with a fire pit, chairs, and two evergreen trees.
A bathroom with a large bathtub, a chair, and a small shelf with plants.
A hotel room with two beds, wooden flooring, a desk with a chair, a microwave, and a potted plant.

9. Pinemark Inn & Suites

Pinemark Inn & Suites
St. Clair
  • Family-friendly destination with seasonal pool and firepits makes for perfect relaxation in St. Clair.
£101
includes taxes & fees
1 Nov - 2 Nov
Pinemark Inn & Suites
A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.
An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

10. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
  • Splash into a family holiday haven at this Sleep Inn & Suites with indoor pool, fitness centre, and kid-friendly amenities.
£103
includes taxes & fees
15 Nov - 16 Nov
Sleep Inn & Suites Hannibal West
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Choose what matters most at family-friendly hotels in Northeast Missouri

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Family-friendly hotels with free breakfast in Northeast Missouri

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.
A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.
A hotel lobby with a reception desk, seating area, and a sign for the general store.
A living room with a flat-screen TV, fireplace, and a couch with pillows.

Depot Inn and Suites

Depot Inn and Suites
La Plata
£71
includes taxes & fees
25 Oct - 26 Oct
Depot Inn and Suites
A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.
A conference room with a long table, multiple chairs, framed artwork on the walls, and a television screen.
A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.
A fitness center with treadmills, stationary bikes, and elliptical machines.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
Kirksville
£100
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Kirksville - University Area by IHG
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.
A bar area with a long counter, multiple bottles, glasses, and a few chairs.
A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.
A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

Oak Hill Inn & Suites

Oak Hill Inn & Suites
Canton
£81
includes taxes & fees
21 Nov - 22 Nov
Oak Hill Inn & Suites
A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.
A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".
A modern hotel lobby with a reception desk, seating area, and large windows.
A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
Kirksville
£69
includes taxes & fees
22 Oct - 23 Oct
Super 8 by Wyndham Kirksville-University Area
A hotel with a brick facade, a central entrance with columns, and a sign indicating it's a Best Western hotel.
A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.
A Best Western hotel with a brick facade, a covered entrance, and a signboard.
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

Best Western On The River

Best Western On The River
Hannibal
£95
includes taxes & fees
25 Oct - 26 Oct
Best Western On The River
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.
A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
£103
includes taxes & fees
15 Nov - 16 Nov
Sleep Inn & Suites Hannibal West
A hotel entrance with a central fountain, large columns, and a clear sky.
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.
A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
£66
includes taxes & fees
15 Nov - 16 Nov
Quality Inn & Suites Hannibal West
A stainless steel ice dispenser with a blue button labeled 'PUSH FOR ICE' in a kitchen setting.
A hotel room with two beds, green walls, and artwork.
A motel with a sign advertising free continental breakfast and internet service.
A reception area with a counter, a trash bin, and a seating area with chairs.

Travelier Motel

Travelier Motel
Macon
£62
includes taxes & fees
21 Nov - 22 Nov
Travelier Motel
A Comfort Inn hotel with a modern design, featuring a covered entrance and a clear sky in the background.
A hotel room with two beds, a desk, a TV, and a view of the outdoors.
An indoor swimming pool with clear water, surrounded by stone flooring, and equipped with multiple chairs and a blue lounge chair.
A modern hotel lobby with a sofa, chairs, a coffee table, and a floor lamp.

Comfort Inn Sullivan

Comfort Inn Sullivan
Sullivan
£93
includes taxes & fees
10 Nov - 11 Nov
Comfort Inn Sullivan
A bathroom with a large bathtub, a chair, and a small shelf with plants.
An outdoor seating area with a fire pit, chairs, and two evergreen trees.
A rooftop patio with outdoor seating, a pool, and a sunset view.
A hotel room with two beds, wooden flooring, a desk with a chair, a microwave, and a potted plant.

Pinemark Inn & Suites

Pinemark Inn & Suites
St. Clair
£101
includes taxes & fees
1 Nov - 2 Nov
Pinemark Inn & Suites
View all properties

Family-friendly hotels with pools in Northeast Missouri

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.
A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.
A hotel lobby with a reception desk, seating area, and a sign for the general store.
A living room with a flat-screen TV, fireplace, and a couch with pillows.

Depot Inn and Suites

Depot Inn and Suites
La Plata
£71
includes taxes & fees
25 Oct - 26 Oct
Depot Inn and Suites
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.
A bar area with a long counter, multiple bottles, glasses, and a few chairs.
A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.
A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

Oak Hill Inn & Suites

Oak Hill Inn & Suites
Canton
£81
includes taxes & fees
21 Nov - 22 Nov
Oak Hill Inn & Suites
A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.
A conference room with a long table, multiple chairs, framed artwork on the walls, and a television screen.
A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.
A fitness center with treadmills, stationary bikes, and elliptical machines.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
Kirksville
£100
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Kirksville - University Area by IHG
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.
A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

Best Western On The River

Best Western On The River
Hannibal
£95
includes taxes & fees
25 Oct - 26 Oct
Best Western On The River
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.
A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
£66
includes taxes & fees
15 Nov - 16 Nov
Quality Inn & Suites Hannibal West
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.
A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
£103
includes taxes & fees
15 Nov - 16 Nov
Sleep Inn & Suites Hannibal West
A Comfort Inn hotel with a modern design, featuring a covered entrance and a clear sky in the background.
A hotel room with two beds, a desk, a TV, and a view of the outdoors.
An indoor swimming pool with clear water, surrounded by stone flooring, and equipped with multiple chairs and a blue lounge chair.
A modern hotel lobby with a sofa, chairs, a coffee table, and a floor lamp.

Comfort Inn Sullivan

Comfort Inn Sullivan
Sullivan
£93
includes taxes & fees
10 Nov - 11 Nov
Comfort Inn Sullivan
A bathroom with a large bathtub, a chair, and a small shelf with plants.
An outdoor seating area with a fire pit, chairs, and two evergreen trees.
A rooftop patio with outdoor seating, a pool, and a sunset view.
A hotel room with two beds, wooden flooring, a desk with a chair, a microwave, and a potted plant.

Pinemark Inn & Suites

Pinemark Inn & Suites
St. Clair
£101
includes taxes & fees
1 Nov - 2 Nov
Pinemark Inn & Suites
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a parking lot.
A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
A hotel room with a bed, a sofa, a desk, and a lamp.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
£70
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A spacious living room with a large painting, a fireplace, a staircase, and modern furniture.
A hotel room with a dining area, a fireplace, and a view of the outdoors.
An outdoor patio with a beige sofa set, two armchairs, and a table.
A hotel room with a large bed, two sofas, a desk, and a TV.

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
Washington
£114
includes taxes & fees
27 Oct - 28 Oct
Best Western Plus Washington Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Northeast Missouri Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"The staff were friendly and helpful. It was a wonderful stay a around"
Irma 1-night trip
Posted 10 hours ago
Drury Plaza Hotel St. Louis Union Station
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

8/10 Good
"Always like to stay here when I come through. I know I’ll get good quality every time."
Kay 1-night trip
Posted 11 hours ago
Embassy Suites by Hilton St. Louis Downtown
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"The room was clean and everything worked. The check-in staff was fantastic. I appreciated everyone as they were cusomtr focused!"
Mary Ann 3-night trip
Posted 13 hours ago
Hollywood Casino & Hotel St. Louis
Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Very friendly staff and we loved the rooftop bar."
Terry 1-night trip
Posted 13 hours ago
Moonrise Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Experience was Great! Room was clean , always a perfect fit."
Carlton 2-night trip
Posted 15 hours ago
Ameristar Casino Resort and Spa
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"The game room was under construction and having to have our parking validated every time was a pain, but otherwise it was perfect."
Scott 2-night trip
Posted 17 hours ago
Clayton Plaza Hotel & Extended Stay
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"Great place to stay if you have an early flight out of STL!"
Charles 1-night trip
Posted 18 hours ago
Renaissance St. Louis Airport Hotel

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