TOP Family-Friendly Hotels in Northeast Missouri, MO for 2026 - Northeast Missouri Family Welcoming Hotels | Expedia.co.uk

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Check availability on Northeast Missouri Family-Friendly Hotels

Tonight

14 Oct - 15 Oct

Tomorrow

15 Oct - 16 Oct

This weekend

16 Oct - 18 Oct

Next weekend

23 Oct - 25 Oct

Our top choices for Northeast Missouri family-friendly hotels

A playground with a slide, swings, and a climbing structure.

A hotel lobby with a reception desk, seating area, and a sign for the general store.

A living room with a flat-screen TV, fireplace, and a couch with pillows.

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

1. Depot Inn and Suites

La Plata

Let the kids loose at this La Plata hotel with indoor pools, playground, and game room for endless family fun.

£75

includes taxes & fees

20 Oct - 21 Oct

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A modern hotel lobby with a reception desk, seating area, and large windows.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A modern living room with a stone wall, a flat-screen TV, a built-in fish tank, a blue sofa, and a large window with a view of a parking lot.

2. Super 8 by Wyndham Kirksville-University Area

Kirksville

£66

includes taxes & fees

31 Oct - 1 Nov

A hotel room with a large bed, a desk with a computer, a television, and a bathtub.

A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.

A bar area with a long counter, multiple bottles, glasses, and a few chairs.

A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

3. Oak Hill Inn & Suites

Canton

£87

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

4. Best Western On The River

Hannibal

Family-friendly riverside hotel offers kids' paradise with indoor and outdoor pools, hot tub, and nearby fun park adventures.

£96

includes taxes & fees

28 Oct - 29 Oct

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

Lobby

An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

5. Hampton Inn Kirksville

Kirksville

£105

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

A hotel entrance with a central fountain, large columns, and a clear sky.

6. Quality Inn & Suites Hannibal West

Hannibal

Family escape with an indoor pool and spacious rooms where kids splash while parents relax at the poolside bar and sun loungers.

£67

includes taxes & fees

8 Nov - 9 Nov

A stainless steel ice dispenser with a blue button labeled 'PUSH FOR ICE' in a kitchen setting.

A reception area with a counter, a trash bin, and a seating area with chairs.

A hotel room with two beds, green walls, and artwork.

A white shower enclosure with a showerhead, a curtain, and a metal grab bar.

7. Travelier Motel

Macon

£63

includes taxes & fees

19 Oct - 20 Oct

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

A Sleep Inn & Suites building with a covered entrance, stone facade, and multiple windows.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

8. Sleep Inn & Suites Hannibal West

Hannibal

Splash into a family holiday haven at this Sleep Inn & Suites with indoor pool, fitness centre, and kid-friendly amenities.

£104

includes taxes & fees

8 Nov - 9 Nov

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Choose what matters most at family-friendly hotels in Northeast Missouri

Breakfast included

Pool

All-inclusive

4 stars

5 stars

Family-friendly hotels with free breakfast in Northeast Missouri

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

A living room with a flat-screen TV, fireplace, and a couch with pillows.

A hotel lobby with a reception desk, a coffee station, and seating areas.

A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.

Depot Inn and Suites

La Plata

£75

includes taxes & fees

20 Oct - 21 Oct

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A modern hotel lobby with a reception desk, seating area, and large windows.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A modern living room with a stone wall, a flat-screen TV, a built-in fish tank, a blue sofa, and a large window with a view of a parking lot.

Super 8 by Wyndham Kirksville-University Area

Kirksville

£66

includes taxes & fees

31 Oct - 1 Nov

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

A hotel entrance with a central fountain, large columns, and a clear sky.

Quality Inn & Suites Hannibal West

Hannibal

£67

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

Best Western On The River

Hannibal

£96

includes taxes & fees

28 Oct - 29 Oct

A hotel room with a large bed, a desk with a computer, a television, and a bathtub.

A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.

A bar area with a long counter, multiple bottles, glasses, and a few chairs.

A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

Oak Hill Inn & Suites

Canton

£87

includes taxes & fees

18 Oct - 19 Oct

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

A snack display area with various treats and a beverage cooler.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

Hampton Inn Kirksville

Kirksville

£105

includes taxes & fees

25 Oct - 26 Oct

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

Sleep Inn & Suites Hannibal West

Hannibal

£104

includes taxes & fees

8 Nov - 9 Nov

A stainless steel ice dispenser with a blue button labeled 'PUSH FOR ICE' in a kitchen setting.

A reception area with a counter, a trash bin, and a seating area with chairs.

A kitchen counter with fruits, a blender, and a refrigerator with a game display.

A hotel room with two beds, green walls, and artwork.

Travelier Motel

Macon

£63

includes taxes & fees

20 Oct - 21 Oct

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

A spacious living area with a staircase, a large painting, and a chandelier.

A modern bathroom with a large mirror, white vanity, and a bathtub.

The Wildwood Hotel

Wildwood

£73

includes taxes & fees

26 Oct - 27 Oct

A hotel room with a bed, a desk with a computer, a TV, and a bathroom with a shower.

A modern kitchen with dark cabinets, a central island with bar stools, and pendant lighting.

A hotel room with a bed, a desk with a chair, a television, and a dining area with chairs.

A hotel entrance with a sign reading "Quality Inn & Suites by Choice Hotels".

Quality Inn & Suites Quincy - Downtown

Quincy

£106

includes taxes & fees

18 Oct - 19 Oct

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Family-friendly hotels with pools in Northeast Missouri

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

A living room with a flat-screen TV, fireplace, and a couch with pillows.

A hotel lobby with a reception desk, a coffee station, and seating areas.

A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.

Depot Inn and Suites

La Plata

£75

includes taxes & fees

20 Oct - 21 Oct

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

A hotel entrance with a central fountain, large columns, and a clear sky.

Quality Inn & Suites Hannibal West

Hannibal

£67

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, a desk with a computer, a television, and a bathtub.

A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.

A bar area with a long counter, multiple bottles, glasses, and a few chairs.

A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

Oak Hill Inn & Suites

Canton

£87

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

Best Western On The River

Hannibal

£96

includes taxes & fees

28 Oct - 29 Oct

A hotel room with a bed, a sofa, a desk, and a lamp.

An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

Comfort Inn & Suites - Hannibal

Hannibal

£70

includes taxes & fees

8 Nov - 9 Nov

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

A snack display area with various treats and a beverage cooler.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

Hampton Inn Kirksville

Kirksville

£105

includes taxes & fees

25 Oct - 26 Oct

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

Sleep Inn & Suites Hannibal West

Hannibal

£104

includes taxes & fees

8 Nov - 9 Nov

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

A spacious living area with a staircase, a large painting, and a chandelier.

A modern bathroom with a large mirror, white vanity, and a bathtub.

The Wildwood Hotel

Wildwood

£73

includes taxes & fees

26 Oct - 27 Oct

A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.

A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.

A fitness center with treadmills, stationary bikes, and elliptical machines.

A reception area with two reception desks, a wall-mounted sign, and a vending machine.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Kirksville

£101

includes taxes & fees

25 Oct - 26 Oct

A Microtel Inn & Suites building with a stone facade, multiple windows, and a covered entrance area.

A reception area with a brown reception desk, a large window, and a wall with the hotel name.

An indoor swimming pool with a tiled floor, wooden beams, and a view of the outdoors through large windows.

A view of a bridge, a building, and a fenced area with construction materials.

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Quincy

£60

includes taxes & fees

8 Nov - 9 Nov

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Northeast Missouri Hotel Reviews

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

8/10 Good

"The property was great but the breakfast menu was the same every morning. I would’ve liked a little more variety. The happy hour cocktails were nice. The room and property were clean. I would’ve liked highly recommend thus property."

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center

10/10 Excellent

"Great place to stay! Highly recommend!"

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"The property itself was maintained ok. It does need to be updated as the carpets and bathrooms are old. Our ceiling in the bathroom was peeling due to the humidity from the shower over the years. The carpet in the rooms and common areas is older. As for the staff everyone was nice and did what was expected of them. I would use this property again to stay as it’s walking distance from everything downtown."

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good

"Hotel staff were excellent, friendly, professional and by far the best reason to re-book. The hotel itself was very clean, located near professional buildings/courts and some eateries within walking distance. The room was clean as well and nicely proportioned with some of the best mattresses/bedding I've experienced. Only slight downside was the breakfast bar--the food and choices were ample and very good (especially the made to order omelets and waffles) but the setting was less than clean and rather worn--not in keeping with the rest of the hotel. All in all, a great place to stay and would definitely book again."

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Location was great for us. Walked to an event. The drinks and food in the evening was nice and breakfast was good as well. Love the character of this one"

Moonrise Hotel

Moonrise Hotel

8/10 Good

"I slept well."

The Westin St. Louis

The Westin St. Louis

10/10 Excellent

"The Westin is a lovely hotel, great location for our trip. Staff was friendly and helpful, we didn't use any of the amenities, but they are nice. The bar is great, and the rooms are very large."

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good

"Wonderful stay for a small bachelorette party. Had a wonderful time!"

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