A large eye sculpture in a park surrounded by trees.

Find Family-Friendly Hotels in Northeast Missouri, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Northeast Missouri Family-Friendly Hotels

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Northeast Missouri family-friendly hotels

A playground with a slide, swings, and a climbing structure.
A hotel lobby with a reception desk, seating area, and a sign for the general store.
A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.
An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

1. Depot Inn and Suites

Depot Inn and Suites
La Plata
  • Let the kids loose at this La Plata hotel with indoor pools, playground, and game room for endless family fun.
£74
includes taxes & fees
25 Oct - 26 Oct
Depot Inn and Suites
A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.
A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.
A reception desk with two computer monitors, a printer, and a keyboard.
A reception area with two reception desks, a wall-mounted sign, and a vending machine.

2. Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
Kirksville
  • Family-friendly fun begins with an indoor pool adventure just a short drive from Thousand Hills State Park for outdoor exploration.
£100
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Kirksville - University Area by IHG
A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.
A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".
A modern hotel lobby with a reception desk, seating area, and large windows.
A modern living room with a stone wall, a flat-screen TV, a built-in fish tank, a blue sofa, and a large window with a view of a parking lot.

3. Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
Kirksville
£61
includes taxes & fees
19 Oct - 20 Oct
Super 8 by Wyndham Kirksville-University Area
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.
A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.
A bar area with a long counter, multiple bottles, glasses, and a few chairs.
A hotel room with a bathtub, two yellow armchairs, a desk with a chair, a small table, and a lamp.

4. Oak Hill Inn & Suites

Oak Hill Inn & Suites
Canton
£87
includes taxes & fees
18 Oct - 19 Oct
Oak Hill Inn & Suites
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A hotel kitchen with a buffet setup, including a coffee station and various food items.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

5. Best Western On The River

Best Western On The River
Hannibal
  • Family-friendly riverside hotel offers kids' paradise with indoor and outdoor pools, hot tub, and nearby fun park adventures.
£95
includes taxes & fees
28 Oct - 29 Oct
Best Western On The River
A stainless steel ice dispenser with a blue button labeled 'PUSH FOR ICE' in a kitchen setting.
A kitchen counter with fruits, a blender, and a refrigerator with a game display.
A white shower enclosure with a showerhead, a curtain, and a metal grab bar.
A hotel room with two beds, green walls, and artwork.

6. Travelier Motel

Travelier Motel
Macon
£59
includes taxes & fees
17 Nov - 18 Nov
Travelier Motel
A modern hotel lobby with multiple seating areas, including a bar and dining tables.
A hotel room with two beds, a desk, a lamp, and a painting on the wall.
An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.
A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

7. Hampton Inn Kirksville

Hampton Inn Kirksville
Kirksville
£104
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn Kirksville
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A hotel entrance with a central fountain, large columns, and a clear sky.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.
A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

8. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
  • Family escape with an indoor pool and spacious rooms where kids splash while parents relax at the poolside bar and sun loungers.
£66
includes taxes & fees
8 Nov - 9 Nov
Quality Inn & Suites Hannibal West
A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.
An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

9. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
  • Splash into a family holiday haven at this Sleep Inn & Suites with indoor pool, fitness centre, and kid-friendly amenities.
£103
includes taxes & fees
8 Nov - 9 Nov
Sleep Inn & Suites Hannibal West
A hotel with a swimming pool, outdoor seating, and a sign for 'Pinemark Inn Suites & Events'.
A hotel with a prominent leaf logo, a covered outdoor area, and a parking lot.
An outdoor seating area with a fire pit, chairs, and two evergreen trees.
A hotel room with two beds, wooden flooring, a desk with a chair, a microwave, and a potted plant.

10. Pinemark Inn & Suites

Pinemark Inn & Suites
St. Clair
  • Family-friendly destination with seasonal pool and firepits makes for perfect relaxation in St. Clair.
£100
includes taxes & fees
1 Nov - 2 Nov
Pinemark Inn & Suites
View all properties

Choose what matters most at family-friendly hotels in Northeast Missouri

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Family-friendly hotels with free breakfast in Northeast Missouri

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.
A living room with a flat-screen TV, fireplace, and a couch with pillows.
A hotel lobby with a reception desk, seating area, and a sign for the general store.
A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.

Depot Inn and Suites

Depot Inn and Suites
La Plata
£74
includes taxes & fees
25 Oct - 26 Oct
Depot Inn and Suites
A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.
A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.
A reception desk with two computer monitors, a printer, and a keyboard.
A reception area with two reception desks, a wall-mounted sign, and a vending machine.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
Kirksville
£100
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Kirksville - University Area by IHG
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.
A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.
A bar area with a long counter, multiple bottles, glasses, and a few chairs.
A hotel room with a bathtub, two yellow armchairs, a desk with a chair, a small table, and a lamp.

Oak Hill Inn & Suites

Oak Hill Inn & Suites
Canton
£87
includes taxes & fees
18 Oct - 19 Oct
Oak Hill Inn & Suites
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.
A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
£103
includes taxes & fees
8 Nov - 9 Nov
Sleep Inn & Suites Hannibal West
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A hotel kitchen with a buffet setup, including a coffee station and various food items.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

Best Western On The River

Best Western On The River
Hannibal
£95
includes taxes & fees
28 Oct - 29 Oct
Best Western On The River
A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.
A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".
A modern hotel lobby with a reception desk, seating area, and large windows.
A modern living room with a stone wall, a flat-screen TV, a built-in fish tank, a blue sofa, and a large window with a view of a parking lot.

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
Kirksville
£61
includes taxes & fees
19 Oct - 20 Oct
Super 8 by Wyndham Kirksville-University Area
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A hotel entrance with a central fountain, large columns, and a clear sky.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.
A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
£66
includes taxes & fees
8 Nov - 9 Nov
Quality Inn & Suites Hannibal West
A modern hotel lobby with multiple seating areas, including a bar and dining tables.
An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.
A snack display area with various treats and a beverage cooler.
A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

Hampton Inn Kirksville

Hampton Inn Kirksville
Kirksville
£104
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn Kirksville
A hotel room with a bed, a lamp, a mirror, and a door.
A grand, circular staircase with white balustrades and a chandelier in the center.
A Town & Country Inn and Suites building with a prominent entrance, multiple windows, and a green roof.
A sign for Town & Country Inn and Suites with a parking lot and a building in the background.

Town & Country Inn and Suites

Town & Country Inn and Suites
Quincy
£107
includes taxes & fees
19 Oct - 20 Oct
Town & Country Inn and Suites
A bathroom with a large bathtub, a chair, and a small shelf with plants.
A hotel with a prominent leaf logo, a covered outdoor area, and a parking lot.
An outdoor seating area with a fire pit, chairs, and two evergreen trees.
A hotel room with two beds, wooden flooring, a desk with a chair, a microwave, and a potted plant.

Pinemark Inn & Suites

Pinemark Inn & Suites
St. Clair
£100
includes taxes & fees
1 Nov - 2 Nov
Pinemark Inn & Suites
View all properties

Family-friendly hotels with pools in Northeast Missouri

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.
A living room with a flat-screen TV, fireplace, and a couch with pillows.
A hotel lobby with a reception desk, seating area, and a sign for the general store.
A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.

Depot Inn and Suites

Depot Inn and Suites
La Plata
£74
includes taxes & fees
25 Oct - 26 Oct
Depot Inn and Suites
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.
A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.
A bar area with a long counter, multiple bottles, glasses, and a few chairs.
A hotel room with a bathtub, two yellow armchairs, a desk with a chair, a small table, and a lamp.

Oak Hill Inn & Suites

Oak Hill Inn & Suites
Canton
£87
includes taxes & fees
18 Oct - 19 Oct
Oak Hill Inn & Suites
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.
A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
£103
includes taxes & fees
8 Nov - 9 Nov
Sleep Inn & Suites Hannibal West
A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.
A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.
A reception desk with two computer monitors, a printer, and a keyboard.
A reception area with two reception desks, a wall-mounted sign, and a vending machine.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
Kirksville
£100
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Kirksville - University Area by IHG
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A hotel kitchen with a buffet setup, including a coffee station and various food items.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

Best Western On The River

Best Western On The River
Hannibal
£95
includes taxes & fees
28 Oct - 29 Oct
Best Western On The River
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A hotel entrance with a central fountain, large columns, and a clear sky.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.
A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
£66
includes taxes & fees
8 Nov - 9 Nov
Quality Inn & Suites Hannibal West
A Comfort Inn hotel with a modern design, featuring a covered entrance and a clear sky in the background.
A hotel room with two beds, a desk, a TV, and a view of the outdoors.
A modern hotel lobby with a sofa, chairs, a coffee table, and a floor lamp.
A modern kitchen with a coffee station, bread display, and a sign that reads "RISE & SHINE".

Comfort Inn Sullivan

Comfort Inn Sullivan
Sullivan
£93
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn Sullivan
A hotel room with a bed, a lamp, a mirror, and a door.
A grand, circular staircase with white balustrades and a chandelier in the center.
A Town & Country Inn and Suites building with a prominent entrance, multiple windows, and a green roof.
A sign for Town & Country Inn and Suites with a parking lot and a building in the background.

Town & Country Inn and Suites

Town & Country Inn and Suites
Quincy
£107
includes taxes & fees
19 Oct - 20 Oct
Town & Country Inn and Suites
A hotel room with a bed, a sofa, a desk, and a lamp.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
£69
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A modern hotel lobby with multiple seating areas, including a bar and dining tables.
An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.
A snack display area with various treats and a beverage cooler.
A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

Hampton Inn Kirksville

Hampton Inn Kirksville
Kirksville
£104
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn Kirksville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Northeast Missouri Hotel Reviews

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"Easy check in"
Mark 1-night trip
Posted 4 hours ago
Renaissance St. Louis Airport Hotel
Moonrise Hotel

Moonrise Hotel

8/10 Good
"Really cute hotel in Delmar Loop. Fun, quirky style. Excellent location, but our room smelled like wet dog."
Elina 1-night trip
Posted 14 hours ago
Moonrise Hotel
Forest Park Hotel by MDR

Forest Park Hotel by MDR

10/10 Excellent
"Great, great, great property. well restored, you know, rung back. You tell us it’s buildings older. Amenities are great. Staff’s great, clean. go above and beyond to try to be helpful as much as they can. I felt safe. Yeah, all around good property"
Anthony 1-night trip
Posted 20 hours ago
Forest Park Hotel by MDR

Explore a world of travel with Expedia