A large eye sculpture in a park surrounded by trees.

Search Business Hotels in Northeast Missouri

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Check availability on Northeast Missouri Business Hotels

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Northeast Missouri business-friendly hotels

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.
A living room with a flat-screen TV, fireplace, and a couch with pillows.
A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.
A hotel lobby with a reception desk, a coffee station, and seating areas.

1. Depot Inn and Suites

Depot Inn and Suites
La Plata
United States
JERROD
£74
includes taxes & fees
25 Oct - 26 Oct
Depot Inn and Suites
A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.
A reception area with two reception desks, a wall-mounted sign, and a vending machine.
A reception desk with two computer monitors, a printer, and a keyboard.
A fitness center with treadmills, stationary bikes, and elliptical machines.

2. Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
Kirksville
United States
Jimmy
£100
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Kirksville - University Area by IHG
A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.
A modern living room with a stone wall, a flat-screen TV, a built-in fish tank, a blue sofa, and a large window with a view of a parking lot.
A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".
A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

3. Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
Kirksville
United States
Michael
£61
includes taxes & fees
26 Oct - 27 Oct
Super 8 by Wyndham Kirksville-University Area
A hotel room with a large bed, a desk with a computer, a television, and a bathtub.
A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.
A bar area with a long counter, multiple bottles, glasses, and a few chairs.
A hotel room with a bathtub, two yellow armchairs, a desk with a chair, a small table, and a lamp.

4. Oak Hill Inn & Suites

Oak Hill Inn & Suites
Canton
United States
Regina
£87
includes taxes & fees
18 Oct - 19 Oct
Oak Hill Inn & Suites
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.
A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

5. Best Western On The River

Best Western On The River
Hannibal
United States
Wei
£95
includes taxes & fees
28 Oct - 29 Oct
Best Western On The River
A modern hotel lobby with multiple seating areas, including a bar and dining tables.
A snack display area with various treats and a beverage cooler.
A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.
A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

6. Hampton Inn Kirksville

Hampton Inn Kirksville
Kirksville
United States
Eric
£104
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Kirksville
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.
A hotel entrance with a central fountain, large columns, and a clear sky.
A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

7. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
United States
Gayle
£66
includes taxes & fees
8 Nov - 9 Nov
Quality Inn & Suites Hannibal West
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

8. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
United States
Patricia
£103
includes taxes & fees
8 Nov - 9 Nov
Sleep Inn & Suites Hannibal West
A bathroom with a large bathtub, a chair, and a small shelf with plants.
An outdoor seating area with a fire pit, chairs, and two evergreen trees.
A rooftop patio with outdoor seating, a pool, and a sunset view.
A hotel with a prominent leaf logo, a covered outdoor area, and a parking lot.

9. Pinemark Inn & Suites

Pinemark Inn & Suites
St. Clair
United States
William
£100
includes taxes & fees
1 Nov - 2 Nov
Pinemark Inn & Suites
A hotel room with two beds, a desk, a chair, and a large window.
Two Whirlpool front-loading washing machines in a laundry room with framed certificates on the wall.
A Super 8 motel with a gas station in the background, featuring a large sign and a well-lit exterior.
A gym with treadmills, an elliptical, and a water dispenser.

10. Super 8 by Wyndham Washington

Super 8 by Wyndham Washington
Washington
United States
Kenneth
£68
includes taxes & fees
16 Nov - 17 Nov
Super 8 by Wyndham Washington
View all properties

Top Northeast Missouri Hotel Reviews

Moonrise Hotel

Moonrise Hotel

8/10 Good
"Really cute hotel in Delmar Loop. Fun, quirky style. Excellent location, but our room smelled like wet dog."
Elina 1-night trip
Posted 9 hours ago
Moonrise Hotel
Forest Park Hotel by MDR

Forest Park Hotel by MDR

10/10 Excellent
"Great, great, great property. well restored, you know, rung back. You tell us it’s buildings older. Amenities are great. Staff’s great, clean. go above and beyond to try to be helpful as much as they can. I felt safe. Yeah, all around good property"
Anthony 1-night trip
Posted 15 hours ago
Forest Park Hotel by MDR
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Nothing was open on the days we stayed there. No bar or space pool close too early. But overall a very nice stay overnight, clean room and spacious."
Lafonza 1-night trip
Posted 15 hours ago
Ameristar Casino Resort and Spa

Frequently asked questions

How much do business hotels in Northeast Missouri cost?
Business hotels in Northeast Missouri range between £61 and £112 per night. This means you can lock in a stay with handy amenities like conference rooms and workspaces at a price that won't stretch the work budget. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Northeast Missouri?
When your next conference or event takes you someplace in Northeast Missouri, you'll have 230 business hotels to pick from.
Why book your business hotel in Northeast Missouri with Expedia?
Expedia is here to help you find a great business hotel when work takes you on the road. From conference spaces and room service to on-site restaurants and more, our stays come with the conveniences you'll need to settle that big contract.
How can I find cheap business hotels in Northeast Missouri?
Click on the "business friendly" filter, listed just under the "traveller experience" heading, to find cheap business hotels in Northeast Missouri. Then narrow your search by your budget and preferred hotel star rating. Basing yourself away from the city centre is another good way to save.

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