All Hotels by Best Western in Mission Valley - 2026 Updated Prices

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Our top choices for Mission Valley Best Western

A hotel lobby with a 'Lobby' sign, palm trees, and a sunset sky.

1. Best Western Seven Seas

Mission Valley

includes taxes & fees

29 Sept - 30 Sept

A hotel breakfast area with a long counter displaying various food items, including fruits, pastries, and a coffee station.

2. Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Mission Valley

Esmeralda

includes taxes & fees

1 Oct - 2 Oct

A modern kitchen area with a self-serve station, including a waffle maker, coffee machine, and various food items.

3. Best Western Chula Vista/Otay Valley Hotel

Otay

Brenda

includes taxes & fees

11 Oct - 12 Oct

4. Best Western San Diego/Miramar Hotel

Miramar

Richard

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, and a large window with a view of the outdoors.

5. Best Western Yacht Harbor Hotel

Point Loma

Arturo

includes taxes & fees

13 Oct - 14 Oct

A spacious lobby with a fireplace, wooden furniture, and a chandelier.

6. Best Western Americana Inn

San Ysidro

Luis

includes taxes & fees

18 Oct - 19 Oct

A modern reception area with a large arched window, a reception desk, a blue sofa, and a round wooden table.

7. Best Western San Diego Pacific Beach/Mission Bay

Bay Park

Guadalupe Pina

includes taxes & fees

22 Oct - 23 Oct

An outdoor patio with wicker furniture, a wooden pergola, and potted plants.

8. Best Western Downtown San Diego

Downtown San Diego

Gloria

includes taxes & fees

29 Sept - 30 Sept

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Top Mission Valley Hotel Reviews

Legacy Resort Hotel & Spa

10/10 Excellent

"Enjoyed my stay"

Hampton Inn San Diego/Mission Valley

8/10 Good

"The price was very reasonable, and the room itself was comfortable and spacious. Overall, we had a decent stay, but there were a couple of things that could be improved. There seemed to be quite a few people around the property who did not appear to be hotel guests, which made the area feel a little uncomfortable at times. On our second day, someone knocked on our door twice. When I checked, I saw a gentleman several rooms down walking toward our room. I closed the door, checked again a moment later, and saw him heading back toward his room. I’m not sure what the situation was, but it definitely made us feel a little uneasy. I reported it to the front desk, and the staff were very receptive and took my concern seriously, which made me feel much safer. Cleanliness could also be improved. The elevators had a strong food/pizza smell, and there was some small trash and debris in the carpeted areas. I do want to give Hampton a lot of credit for their customer service. After checking out, I realized I had forgotten a package in my room. The staff went above and beyond to help me retrieve it, and everything was found exactly where I had left it. I really appreciated how helpful and trustworthy they were. Staff: 10/10 Cleanliness: 7/10 Overall, it was a good value and the staff were excellent. With a little more attention to cleanliness and security around the property, the experience would be much better."

Element by Marriott San Diego Mission Valley

8/10 Good

"It was very clean, the set up was nice in the room with the dishwasher, microwaved and fridge and separate freezer. I really appreciated the filtered water so we didn’t have to buy water. The microwave was not plugged but I found the plug above the device. There wasn’t any bedding provided for the pull out couch so we didn’t use any for the first night and asked for it for the next night we stayed. We had access to the pool at the Marriott across the way but there was not a hot tub sadly. My biggest complaint would be the noise. The walls and floors are very very thin so any walking around above us felt like a giant stomping around. We could hear the chairs scrape across the floor above us too. Otherwise the hotel would have been perfect. The staff was great. WiFi could have been better as well."

Find out more about Mission Valley

Pocket Guide: San Diego Mission Valley Hotels

Mission Valley is a family-friendly, economical neighborhood known for being upscale and having ample choices for restaurants, bars, and coffee shops. Many visitors come to bask in its beautiful outdoor settings, namely the sea and beaches. With hotels and holiday apartments to suit everyone's tastes, Mission Valley serves as a good starting point for exploring the greater San Diego area.

Sightseeing around Mission Valley

Some top attractions include the area's historic landmarks and zoo. The local culture at Starlight Bowl, Spanish Village Art Center, and San Diego Natural History Museum might be just what you're looking for. Learn about local history at House of Pacific Relations International Cottages and Athenaeum Music and Arts Library. Mission Basilica San Diego de Alcala, Rock Church, and San Diego Coronado Bridge are a few landmarks that can't be missed. Bring the family to San Diego Zoo, Balboa Park Carousel, and Heritage Park.

You can get some shopping done while you're here, or take part in any number of other activities. Dip your toes in the water and soak up the sun at Coronado Beach, Mission Beach, and Ocean Beach Park. Desert Garden, Balboa Park, or Japanese Friendship Garden are ideal spots to enjoy the outdoors. Plan to do some shopping while in town? Consider Mission Valley Mall, Fashion Valley Mall, and Westfield Horton Plaza. Qualcomm Stadium, Riverwalk Golf Club, and Balboa Park Golf Course are other spots for some local fun.

A few of the area's most popular attractions are University of San Diego, San Diego State University, and Seaworld. You can also check out Reuben H. Fleet Science Center, San Diego Museum of Art, and San Diego Model Railroad Museum.

Getting around Mission Valley

If you want to get around the city, Rio Vista Station is the closest metro stop. Others nearby include Fenton Parkway Station and Qualcomm Stadium Station.

Mission Valley is 4.7 miles (7.6 km) from the airport in San Diego, CA (SAN-San Diego Intl.). You can also fly in and out of Tijuana, Baja California Norte (TIJ-General Abelardo L. Rodriguez Intl.), which is located 18.3 miles (29.4 km) away.

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Check prices for these dates

Our top choices for Mission Valley Best Western

1. Best Western Seven Seas

2. Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

3. Best Western Chula Vista/Otay Valley Hotel

4. Best Western San Diego/Miramar Hotel

5. Best Western Yacht Harbor Hotel

6. Best Western Americana Inn

7. Best Western San Diego Pacific Beach/Mission Bay

8. Best Western Downtown San Diego

9. Best Western Santee Lodge

10. Best Western Poway/San Diego Hotel

Top Mission Valley Hotel Reviews

Legacy Resort Hotel & Spa

Hampton Inn San Diego/Mission Valley

The Atwood Hotel San Diego - SeaWorld/Zoo

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Ramada Suites by Wyndham San Diego/Hotel Circle Area

Element by Marriott San Diego Mission Valley

Find out more about Mission Valley

Pocket Guide: San Diego Mission Valley Hotels

Sightseeing around Mission Valley

Getting around Mission Valley

Explore a world of travel with Expedia

Search Hotels by Best Western in Mission Valley from £73

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Mission Valley Best Western

1. Best Western Seven Seas

2. Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

3. Best Western Chula Vista/Otay Valley Hotel

4. Best Western San Diego/Miramar Hotel

5. Best Western Yacht Harbor Hotel

6. Best Western Americana Inn

7. Best Western San Diego Pacific Beach/Mission Bay

8. Best Western Downtown San Diego

9. Best Western Santee Lodge

10. Best Western Poway/San Diego Hotel

Top Mission Valley Hotel Reviews

Legacy Resort Hotel & Spa

Find out more about Mission Valley

Pocket Guide: San Diego Mission Valley Hotels

Sightseeing around Mission Valley

Getting around Mission Valley

Explore a world of travel with Expedia