Title: Mission Hope Cancer Center in Santa Maria | Expedia.co.uk [Mission Hope Cancer Center Hotels](https://expedia.co.uk/Mission-Hope-Cancer-Center-Hotels.0-l553248621560560291-0.Travel-Guide-Filter-Hotels)[Flights to Santa Maria](https://expedia.co.uk/Cheap-Flights-To-Santa-Maria.d3224.Travel-Guide-Flights)[Things to do in Santa Maria](https://expedia.co.uk/Things-To-Do-In-Santa-Maria.d3224.Travel-Guide-Activities)[Mission Hope Cancer Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-Hope-Cancer-Center.d553248621560560291.Car-Hire-Guide)[Santa Maria Holidays](https://expedia.co.uk/Santa-Maria.d3224.Holidays-City-Breaks) # Mission Hope Cancer Center ## Visit Mission Hope Cancer Center Activities [Santa Maria travel guide](https://expedia.co.uk/Santa-Maria.dx3224) * * * * * * ### Popular places to visit #### Marian Regional Medical Center If Marian Regional Medical Center is what brings you to town, hopefully you'll have a chance to explore more of Santa Maria. [](https://expedia.co.uk/Marian-Regional-Medical-Center-Santa-Maria.d553248621560560290.Attraction) #### Pacific Conservatory Theatre You can enjoy a show at Pacific Conservatory Theatre on your trip to Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Marian-And-Severson-Theaters-Santa-Maria.d6209504.Attraction) #### Simas Park After visiting Simas Park, make a plan to see the other sights and activities in Santa Maria. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Simas-Park-Santa-Maria.d6200043.Attraction) #### Natural History Museum You can spend an afternoon studying the exhibits at Natural History Museum in Santa Maria. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Natural-History-Museum-Santa-Maria.d6209508.Attraction) #### Regal Edwards Santa Maria & RPX You can take time to visit Regal Edwards Santa Maria & RPX during your travels to Santa Maria. Visit the shops and top-notch restaurants in this family-friendly area. [](https://expedia.co.uk/Regal-Edwards-Santa-Maria-RPX-Santa-Maria.d941654002322817024.Attraction) #### Santa Maria Valley Discovery Museum You can take time to visit Santa Maria Valley Discovery Museum during your travels to Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Santa-Maria-Valley-Discovery-Museum-Santa-Maria.d6200056.Attraction) * * * ## Top Hotel Deals ## Check availability on hotels close to Mission Hope Cancer Center [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-04&endDate=2025-11-05) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-04&endDate=2025-11-05) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-04&endDate=2025-11-05) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-04&endDate=2025-11-05)[4 Nov - 5 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-04&endDate=2025-11-05) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-05&endDate=2025-11-06) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-05&endDate=2025-11-06) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-05&endDate=2025-11-06) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-11-05&endDate=2025-11-06)[5 Nov - 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16 Nov](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=14%2F11%2F2025&endDate=16%2F11%2F2025) ![Historic Santa Maria Inn](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Historic Santa Maria Inn 801 S Broadway, Santa Maria, CA [](https://expedia.co.uk/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Motel 6 Santa Maria, CA - North](https://images.trvl-media.com/lodging/1000000/1000000/996400/996393/5265532a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Motel 6 Santa Maria, CA - North 2040 North Preisker Lane, Santa Maria, CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Motel-6-Santa-Maria.h996393.Hotel-Information) ![Villa Motel](https://images.trvl-media.com/lodging/114000000/113750000/113740100/113740019/c178d50c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Villa Motel 1204 S Broadway, Santa Maria, CA [](https://expedia.co.uk/Santa-Maria-Hotels-Villa-Motel.h113740019.Hotel-Information) ![Hotel Avanti](https://images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/c06a634d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Avanti 1107 N Broadway, Santa Maria, CA [](https://expedia.co.uk/Santa-Maria-Hotels-Hotel-Avanti.h102791710.Hotel-Information) ![Hampton Inn & Suites Santa Maria](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/1cf0eed4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn & Suites Santa Maria 2190 Preisker Lane, Santa Maria, CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Oxford Suites Pismo Beach 651 Five Cities Dr, Pismo Beach, CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Best Western Casa Grande Inn](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/e16ece78_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Casa Grande Inn 850 Oak Park Blvd, Pismo Beach, CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) ![Edgewater Inn And Suites](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/3d1c5694_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Edgewater Inn And Suites 280 Wadsworth Ave, Pismo Beach, CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![Days Inn by Wyndham Arroyo Grande/Pismo Beach](https://images.trvl-media.com/lodging/14000000/13280000/13279100/13279003/91813495_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Days Inn by Wyndham Arroyo Grande/Pismo Beach 555 Camino Mercado, Arroyo Grande, CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Pismo-View-Inn.h13279003.Hotel-Information) [See all 1,436 properties in Mission Hope Cancer Center](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=553248621560560291) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in Santa Maria](https://www.expedia.co.uk/4Star-Santa-Maria-Hotels.s40-0-d3224.Travel-Guide-Filter-Hotels) - [Apartments in Santa Maria](https://www.expedia.co.uk/Santa-Maria-Apartments.d3224-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Santa Maria](https://www.expedia.co.uk/Santa-Maria-Condos.d3224-aaCondos.Travel-Guide-Accommodation) - [Beach Resorts & in Santa Maria](https://www.expedia.co.uk/Santa-Maria-Hotels-Beach-Hotels.0-0-d3224-tBeachHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Santa Maria](https://www.expedia.co.uk/Santa-Maria-Hotels-Boutique-Hotel.0-0-d3224-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Santa Maria](https://www.expedia.co.uk/Santa-Maria-Hotels-Casino-Hotel.0-0-d3224-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Santa Maria](https://www.expedia.co.uk/Santa-Maria-Hotels-Gay-Friendly-Hotel.0-0-d3224-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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[Demetria Estate Winery](https://www.expedia.co.uk/Demetria-Estate-Winery-Santa-Maria.d553248621533118345.Attraction) - [Guadalupe-Nipomo Dunes](https://www.expedia.co.uk/Guadalupe-Nipomo-Dunes-Guadalupe.d6207567.Attraction) - [Guadalupe Holidays](https://www.expedia.co.uk/Guadalupe.d6204275.Holidays-City-Breaks) - [Hans Christian Andersen Museum](https://www.expedia.co.uk/Hans-Christian-Andersen-Museum-Solvang.d6177315.Attraction) - [Laetitia Vineyard and Winery](https://www.expedia.co.uk/Laetitia-Vineyard-And-Winery-Nipomo.d553248621532639602.Attraction) - [Lompoc Holidays](https://www.expedia.co.uk/Lompoc.d8560.Holidays-City-Breaks) - [Los Olivos Holidays](https://www.expedia.co.uk/Los-Olivos.d180640.Holidays-City-Breaks) - [Monarch Butterfly Grove](https://www.expedia.co.uk/Monarch-Butterfly-Grove-Pismo-Beach.d6134090.Attraction) - [Montaña de Oro State Park](https://www.expedia.co.uk/Montana-De-Oro-State-Park-California.d553248621532639980.Attraction) - [Morro Bay State Park](https://www.expedia.co.uk/Morro-Bay-State-Park-California.d6063429.Attraction) - [Morro Bay Holidays](https://www.expedia.co.uk/Morro-Bay.d8976.Holidays-City-Breaks) - [Morro Strand State Beach](https://www.expedia.co.uk/Morro-Strand-State-Beach-California.d6307797.Attraction) - [Pismo Beach Pier](https://www.expedia.co.uk/Pismo-Beach-Pier-Downtown-Pismo-Beach.d6128098.Attraction) - [Pismo Beach Surf Shop](https://www.expedia.co.uk/Pismo-Beach-Surf-Shop-Downtown-Pismo-Beach.d553248621532639585.Attraction) - [Pismo Beach Holidays](https://www.expedia.co.uk/Pismo-Beach.d9118.Holidays-City-Breaks) - [Roblar Winery](https://www.expedia.co.uk/Roblar-Winery-Santa-Ynez.d553248635023248449.Attraction) - [San Luis Obispo Holidays](https://www.expedia.co.uk/San-Luis-Obispo.d6046822.Holidays-City-Breaks) - [Santa Barbara Wine Country Holidays](https://www.expedia.co.uk/Santa-Barbara-Wine-Country.d553248634340940978.Holidays-City-Breaks) - [Santa Margarita Holidays](https://www.expedia.co.uk/Santa-Margarita.d6150927.Holidays-City-Breaks) - [Santa Maria Holidays](https://www.expedia.co.uk/Santa-Maria.d3224.Holidays-City-Breaks) - [Visit Santa Maria](https://www.expedia.co.uk/Santa-Maria.dx3224) - [Santa Ynez Holidays](https://www.expedia.co.uk/Santa-Ynez.d9916.Holidays-City-Breaks) - [Simas Park](https://www.expedia.co.uk/Simas-Park-Santa-Maria.d6200043.Attraction) - [Solvang Vintage Motorcycle Museum](https://www.expedia.co.uk/Solvang-Vintage-Motorcycle-Museum-Solvang.d6325037.Attraction) - [Solvang Holidays](https://www.expedia.co.uk/Solvang.d9797.Holidays-City-Breaks) - [Sunstone Vineyards & Winery](https://www.expedia.co.uk/Sunstone-Vineyards-Winery-Santa-Ynez.d631271869111926784.Attraction) - [Wolff Vineyards](https://www.expedia.co.uk/Wolff-Vineyards-San-Luis-Obispo.d553248634340803878.Attraction) - [Avis Rental Cars in Santa Maria](https://www.expedia.co.uk/Avis-Car-Rentals-In-Santa-Maria.d3224-c41.Car-Rental-Guide-Suppliers) - [Rental cars Santa Maria Public airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria-Public.d6031989.Car-Hire-Guide) - [Car hire Santa Maria](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Maria.d3224.Car-Hire-Guide) - [Enterprise Rental Cars in Santa Maria](https://www.expedia.co.uk/Enterprise-Car-Rentals-In-Santa-Maria.d3224-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Santa Maria](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Santa-Maria.d3224-c40.Car-Rental-Guide-Suppliers) - [Surprice Car Rentals Rental Cars in Santa Maria](https://www.expedia.co.uk/SurPrice-Car-Rentals-Car-Rentals-In-Santa-Maria.d3224-c1034.Car-Rental-Guide-Suppliers) - [People Carrier Car Hire in Santa Maria](https://www.expedia.co.uk/Van-Car-Rentals-In-Santa-Maria.d3224-tVan.Car-Rental-Guide-Class) - [Santa Maria Holiday Rentals](https://www.expedia.co.uk/Santa-Maria-Holiday-Rentals.d3224.Travel-Guide-HolidayRentals) - [Things to do in Santa Maria](https://www.expedia.co.uk/Things-To-Do-In-Santa-Maria.d3224.Travel-Guide-Activities)