Title: Mission Hope Cancer Center in Santa Maria | Expedia.co.uk [Mission Hope Cancer Center Hotels](https://expedia.co.uk/Mission-Hope-Cancer-Center-Hotels.0-l553248621560560291-0.Travel-Guide-Filter-Hotels)[Flights to Santa Maria](https://expedia.co.uk/Cheap-Flights-To-Santa-Maria.d3224.Travel-Guide-Flights)[Things to do in Santa Maria](https://expedia.co.uk/Things-To-Do-In-Santa-Maria.d3224.Travel-Guide-Activities)[Mission Hope Cancer Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-Hope-Cancer-Center.d553248621560560291.Car-Hire-Guide)[Santa Maria Holidays](https://expedia.co.uk/Santa-Maria.d3224.Holidays-City-Breaks) # Mission Hope Cancer Center ## Visit Mission Hope Cancer Center Activities [Santa Maria travel guide](https://expedia.co.uk/Santa-Maria.dx3224) --- --- ## Plan a trip to see Mission Hope Cancer Center Price found within the past 48 hours. Click for updated prices. ![Pea Soup Andersen's Inn](https://images.trvl-media.com/lodging/1000000/20000/19400/19331/1b7acd45_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Pea Soup Andersen's Inn £670 per person 28 Feb - 7 Mar found 1 day ago Return direct flight included London (LON) to San Luis Obispo (SBP) 9.2/10 Wonderful! (1,774 reviews) The staff was great. The front desk was very friendly and enuthistic. The court yard was very nice like the images displayed. parking was a bit trickey but still plenty. Overall very cozy and nice stay. Reviewed on 20 Dec 2025 ### Popular places to visit #### Marian Regional Medical Center If Marian Regional Medical Center is what brings you to town, hopefully you'll have a chance to explore more of Santa Maria. [](https://expedia.co.uk/Marian-Regional-Medical-Center-Santa-Maria.d553248621560560290.Attraction) #### Pacific Conservatory Theatre You can enjoy a show at Pacific Conservatory Theatre on your trip to Santa Maria. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Marian-And-Severson-Theaters-Santa-Maria.d6209504.Attraction) #### Simas Park After visiting Simas Park, make a plan to see the other sights and activities in Santa Maria. While in this romantic area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Simas-Park-Santa-Maria.d6200043.Attraction) #### Natural History Museum You can spend an afternoon studying the exhibits at Natural History Museum in Santa Maria. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Natural-History-Museum-Santa-Maria.d6209508.Attraction) #### Regal Edwards Santa Maria & RPX You can take time to visit Regal Edwards Santa Maria & RPX during your travels to Santa Maria. Visit the shops and top-notch restaurants in this family-friendly area. [](https://expedia.co.uk/Regal-Edwards-Santa-Maria-RPX-Santa-Maria.d941654002322817024.Attraction) #### Santa Maria Valley Discovery Museum You can take time to visit Santa Maria Valley Discovery Museum during your travels to Santa Maria. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Santa-Maria-Valley-Discovery-Museum-Santa-Maria.d6200056.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Mission Hope Cancer Center [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-12-21&endDate=2025-12-22)[21 Dec - 22 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-12-21&endDate=2025-12-22) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-12-22&endDate=2025-12-23)[22 Dec - 23 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=2025-12-22&endDate=2025-12-23) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[26 Dec - 28 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621560560291&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025) ![Historic Santa Maria Inn](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Historic Santa Maria Inn 801 S Broadway Santa Maria CA [](https://expedia.co.uk/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Hampton Inn & Suites Santa Maria](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/1cf0eed4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn & Suites Santa Maria 2190 Preisker Lane Santa Maria CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) ![Homewood Suites by Hilton Santa Maria](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3837h2556x3y4-e2ba7794_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Homewood Suites by Hilton Santa Maria 2100 N Broadway Santa Maria CA [](https://expedia.co.uk/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Oxford Suites Pismo Beach 651 Five Cities Dr Pismo Beach CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Aloha Inn](https://images.trvl-media.com/lodging/1000000/20000/14700/14623/3e6ea086_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Aloha Inn 611 El Camino Real Arroyo Grande CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Aloha-Inn.h14623.Hotel-Information) ![Hilton Garden Inn San Luis Obispo/Pismo Beach](https://images.trvl-media.com/lodging/2000000/1620000/1619200/1619196/2231ae59_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden Inn San Luis Obispo/Pismo Beach 601 James Way Pismo Beach CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Hilton-Garden-Inn-San-Luis-Obispo-Pismo-Beach.h1619196.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### SeaCrest OceanFront Hotel 2241 Price Street Pismo Beach CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Hampton Inn & Suites Arroyo Grande/Pismo Beach Area, CA](https://images.trvl-media.com/lodging/3000000/2480000/2470300/2470266/4fe8e56d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn & Suites Arroyo Grande/Pismo Beach Area, CA 1400 W Branch Street Arroyo Grande CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Arroyo-GrandePismo-Beach-Area.h2470266.Hotel-Information) ![Best Western Casa Grande Inn](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/e16ece78_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Casa Grande Inn 850 Oak Park Blvd Pismo Beach CA [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) [See all 1,432 properties in Mission Hope Cancer Center](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=553248621560560291) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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