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Check prices for these dates

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

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Our top choices for Mission Hope Cancer Center hotels

A spacious dining area with wooden tables and chairs, large windows, and a chandelier.

1. Best Western Plus Big America

Best Western Plus Big America
2.5 star property
1.8 mi from Mission Hope Cancer Center
8.8 out of 10, Excellent, (1,002 reviews)
"Rooms are very clean and outside area is well maintained. Pet friendly rooms at no charge, definitely a plus."
United States
G
The price is £79
includes taxes & fees
22 Nov - 23 Nov
Best Western Plus Big America
A hotel room with a large flat-screen TV mounted on the wall, a bedside table with a lamp, a mirror, and a bed.

2. Hotel Avanti

Hotel Avanti
2.5 star property
1.5 mi from Mission Hope Cancer Center
8.6 out of 10, Excellent, (517 reviews)
"Absolutely wonderful hotel."
United States
Samantha
The price is £68
includes taxes & fees
10 Nov - 11 Nov
Hotel Avanti
A courtyard with a fountain, palm trees, and string lights.

3. Historic Santa Maria Inn

Historic Santa Maria Inn
3.5 star property
1.4 mi from Mission Hope Cancer Center
8.4 out of 10, Very good, (2,416 reviews)
"I really enjoyed my stay here"
United States
Michael
The price is £74
includes taxes & fees
1 Dec - 2 Dec
Historic Santa Maria Inn
A reception desk with a 'Welcome' sign, a painting of a landscape, and a bookshelf with magazines.

4. ECONOMY INN

ECONOMY INN
2.5 star property
1.3 mi from Mission Hope Cancer Center
8.2 out of 10, Very good, (110 reviews)
"Clean room lovely staff "
United States
Salina
The price is £63
includes taxes & fees
10 Nov - 11 Nov
ECONOMY INN
A hotel room with a bed, a wooden dresser, a desk with a chair, and a nightstand with a lamp.

5. Villa Motel

Villa Motel
2.0 star property
1.5 mi from Mission Hope Cancer Center
8.0 out of 10, Very good, (489 reviews)
"Place was really nice"
United States
Ryan
The price is £51
includes taxes & fees
10 Nov - 11 Nov
Villa Motel
A modern restaurant with wooden flooring, red seating, and a kitchen area with a counter and decorative items.

6. Quality Inn & Suites Santa Maria

Quality Inn & Suites Santa Maria
2.0 star property
1.8 mi from Mission Hope Cancer Center
8.0 out of 10, Very good, (1,002 reviews)
"Parking was close by and they had charging station ! Staff was amazing."
United States
Jennifer
The price is £79
includes taxes & fees
15 Nov - 16 Nov
Quality Inn & Suites Santa Maria
A hotel room with two beds, a nightstand with a phone, wall-mounted lamps, and a window with blue curtains.

7. Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria
2.0 star property
0.5 mi from Mission Hope Cancer Center
7.0 out of 10, Good, (1,001 reviews)
"Great staff. Nice property."
United States
Megan
The price is £59
includes taxes & fees
6 Dec - 7 Dec
Days Inn by Wyndham Santa Maria
A swimming pool with lounge chairs and a small building in the background.

8. Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South
2.0 star property
0.3 mi from Mission Hope Cancer Center
6.2 out of 10, (624 reviews)
"Highly recommend very clean quite and friendly"
United States
Amy
The price is £75
includes taxes & fees
22 Nov - 23 Nov
Motel 6 Santa Maria, CA - South
An outdoor patio with tables and chairs, a bottle of wine, and a glass of red wine.

9. Wine Stone Inn

Wine Stone Inn
5.0 star property
6.3 mi from Mission Hope Cancer Center
9.8 out of 10, Exceptional, (712 reviews)
"Clean rooms, friendly staff, great location"
United States
DALLAS Cooper
The price is £120
includes taxes & fees
15 Nov - 16 Nov
Wine Stone Inn
A modern dining area with a long table, cushioned seating, and a kitchen in the background.

10. Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria
2.5 star property
2.2 mi from Mission Hope Cancer Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Suites were clean and spacious"
United States
Yesenia
The price is £95
includes taxes & fees
6 Dec - 7 Dec
Hampton Inn & Suites Santa Maria
An outdoor seating area with modern furniture, a glass-top fire feature, and a view of a building with balconies.

11. Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria
3.0 star property
2.1 mi from Mission Hope Cancer Center
9.2 out of 10, Wonderful, (354 reviews)
"Room was clean and breakfast was great."
United States
Rukshana
The price is £100
includes taxes & fees
6 Dec - 7 Dec
Homewood Suites by Hilton Santa Maria
A modern hotel lobby with a long wooden reception desk, multiple bar stools, and pendant lighting.

12. Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria
3.0 star property
2.1 mi from Mission Hope Cancer Center
8.6 out of 10, Excellent, (827 reviews)
"Clean room, nice staff, would stay there again!"
United States
Jim
The price is £91
includes taxes & fees
29 Nov - 30 Nov
Fairfield Inn & Suites by Marriott Santa Maria
Point of interest

13. Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG
2.5 star property
2.1 mi from Mission Hope Cancer Center
8.6 out of 10, Excellent, (1,000 reviews)
"Good kitchenette, free laundry services shower curtain rod was a little off center and internet can be a little slow but overall great stay"
United States
Jeremy
The price is £83
includes taxes & fees
15 Nov - 16 Nov
Candlewood Suites Santa Maria by IHG
A house with a porch, steps, and a fence.

14. Kaleidoscope Inn & Gardens

Kaleidoscope Inn & Gardens
2.5 star property
7.1 mi from Mission Hope Cancer Center
8.6 out of 10, Excellent, (224 reviews)
"Plusses: pet-friendly, ni"
United States
Gigi
The price is £109
includes taxes & fees
29 Nov - 30 Nov
Kaleidoscope Inn & Gardens
A house with a stone exterior, large windows, and a small garden with a rock feature.

15. Solaire Inn & Suites

Solaire Inn & Suites
2.5 star property
2.3 mi from Mission Hope Cancer Center
8.6 out of 10, Excellent, (1,004 reviews)
"great place"
United States
Russel
The price is £52
includes taxes & fees
10 Nov - 11 Nov
Solaire Inn & Suites
A hotel reception area with a counter, a TV displaying news, framed pictures on the wall, and a sign indicating the hotel name 'motel 6'.

16. Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North
2.0 star property
2.1 mi from Mission Hope Cancer Center
7.8 out of 10, Good, (1,238 reviews)
"Friendly front desk guy, clean room, decent bed, quiet…couldn’t have been better."
United States
Jake
The price is £43
includes taxes & fees
15 Nov - 16 Nov
Motel 6 Santa Maria, CA - North
A hotel room with a bed, a nightstand, a lamp, a window with curtains, and a radiator.

17. Colonial Motel

Colonial Motel
2.0 star property
2.1 mi from Mission Hope Cancer Center
6.6 out of 10, (234 reviews)
"Clean rooms, smaller well kept motel in a good location. "
United States
Darren
The price is £74
includes taxes & fees
10 Dec - 11 Dec
Colonial Motel
A dining area with a round table, four white chairs, and a yellow bowl.

18. Retro cottage on Private Rd near park

Retro cottage on Private Rd near park
3.0 star property
3.8 mi from Mission Hope Cancer Center
The price is £169
includes taxes & fees
10 Nov - 11 Nov
Retro cottage on Private Rd near park
A modern kitchen with white cabinets, a black countertop, stainless steel appliances, and a view to the outside.

19. MCM 2 bed/1 bath on Private Rd near park

MCM 2 bed/1 bath on Private Rd near park
3.0 star property
3.8 mi from Mission Hope Cancer Center
The price is £202
includes taxes & fees
10 Nov - 11 Nov
MCM 2 bed/1 bath on Private Rd near park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Mission Hope Cancer Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious dining area with wooden tables and chairs, large windows, and a chandelier.
Best Western Plus Big America
2.5 star property
8.8
Excellent
1,002 reviews
View
A hotel room with a large flat-screen TV mounted on the wall, a bedside table with a lamp, a mirror, and a bed.
Hotel Avanti
2.5 star property
8.6
Excellent
517 reviews
View
A courtyard with a fountain, palm trees, and string lights.
Historic Santa Maria Inn
3.5 star property
8.4
Very good
2,416 reviews
View
A reception desk with a 'Welcome' sign, a painting of a landscape, and a bookshelf with magazines.
ECONOMY INN
2.5 star property
8.2
Very good
110 reviews
View
A hotel room with a bed, a wooden dresser, a desk with a chair, and a nightstand with a lamp.
Villa Motel
2.0 star property
8.0
Very good
489 reviews
View

Top Mission Hope Cancer Center Hotel Reviews

Oxford Suites Pismo Beach

Oxford Suites Pismo Beach

10/10 Excellent
"This is a solid choice location is great - 5 minute dive to pismo pier. Rooms are comfortable with really nice staff - from check in to gregarious bartender. Free drink at check in and solid breakfast with nice pool and grounds. Solid value for price would stay here again."
Mike 1-night trip
Posted 1 hour ago
Oxford Suites Pismo Beach

Frequently asked questions

What's the area like around Mission Hope Cancer Center?
Mission Hope Cancer Center is located in a family-friendly area of Santa Maria known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 10 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mission Hope Cancer Center?
Historic Santa Maria Inn is one of the top choices for your stay based on our traveller data, and this hotel offers 2 bars and a restaurant. It's located 1.4 mi (2.2 km) from Mission Hope Cancer Center. Other good options within 5 miles include Villa Motel and Homewood Suites by Hilton Santa Maria.
How many hotels will I be able to find near Mission Hope Cancer Center?
Expedia has 10 hotels and other accommodation options within a mile from Mission Hope Cancer Center.
If I need to cancel the hotel reservation for my stay near Mission Hope Cancer Center, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Mission Hope Cancer Center.
What can I see and do near Mission Hope Cancer Center?
Study the collections at Santa Maria Valley Historical Society, Natural History Museum or Santa Maria Museum of Flight. You can enjoy live performances at Pacific Conservatory Theatre and Santa Maria Civic Theatre. Children's Resource & Referral (CRR) Discovery Museum, Rancho Bowl and Santa Maria Fairpark are fun stops for the whole family while you're in town.