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Check prices for these dates

Tonight
24 Sept - 25 Sept
Tomorrow
25 Sept - 26 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Mission Hope Cancer Center hotels

A restaurant with long wooden tables and booths, hanging plants, and a decorative ceiling.
A hotel room with a kitchenette, a sofa, a coffee table, and a framed picture on the wall.
A spacious living area with a grand piano, a chandelier, and a large window offering a view of the outdoors.
A hotel room with two beds, a large window with curtains, a framed picture on the wall, and a lamp on the nightstand.

1. Best Western Plus Big America

Best Western Plus Big America
1.8 mi from Mission Hope Cancer Center
United States
Marivic
£93
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus Big America
A hotel room with a large flat-screen TV mounted on the wall, a bedside table with a lamp, a mirror, and a bed.
A modern living room with a grey sofa, a blue chair, and a TV mounted on the wall.
A spacious living area with a sofa, armchairs, a coffee table, and a kitchen area with a refrigerator and cabinets.
A spacious living area with a kitchen, a dining area, and a seating area with a coffee table and sofas.

2. Hotel Avanti

Hotel Avanti
1.5 mi from Mission Hope Cancer Center
United States
Vanessa
£64
includes taxes & fees
27 Sept - 28 Sept
Hotel Avanti
A courtyard with a fountain, palm trees, and string lights.
A bar area with a long wooden counter, multiple stools, and a brick wall backdrop.
An outdoor wedding venue with rows of white chairs and floral centerpieces.
A restaurant with a long, curved seating area featuring cushioned booths and tables set for dining.

3. Historic Santa Maria Inn

Historic Santa Maria Inn
1.4 mi from Mission Hope Cancer Center
United States
Britney
£90
includes taxes & fees
27 Sept - 28 Sept
Historic Santa Maria Inn
A hotel room with a bed, a wooden dresser, a desk with a chair, and a nightstand with a lamp.
A motel with multiple rooms, a parking lot, and palm trees.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a window with curtains.
A reception area with a wooden counter, a bulletin board, and a door leading outside.

4. Villa Motel

Villa Motel
1.5 mi from Mission Hope Cancer Center
United States
Tina
£47
includes taxes & fees
25 Oct - 26 Oct
Villa Motel
A hotel room with a bed, desk, TV, and ceiling fan.
A living room with a beige wall, a ceiling fan, a black refrigerator, a brown sofa, a wooden coffee table, and a window with blinds.
A hotel lobby with a brown leather sofa, a coffee table, a floral rug, a Monster energy drink fridge, and a kitchen area in the background.
A swimming pool with lounge chairs, palm trees, and a covered area with a vending machine.

5. Quality Inn & Suites Santa Maria

Quality Inn & Suites Santa Maria
1.8 mi from Mission Hope Cancer Center
United States
michael
£87
includes taxes & fees
4 Oct - 5 Oct
Quality Inn & Suites Santa Maria
A hotel room with two beds, a nightstand with a phone, wall-mounted lamps, and a window with blue curtains.
A Days Inn hotel with a sunny sign, palm trees, and a two-story building.
A hotel room with a flat-screen TV, a desk with a lamp, a chair, a coffee maker, a microwave, and a small refrigerator.
A clear swimming pool with a red border, surrounded by palm trees and a lounge area with chairs.

6. Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria
0.5 mi from Mission Hope Cancer Center
United Kingdom
David
£62
includes taxes & fees
4 Oct - 5 Oct
Days Inn by Wyndham Santa Maria
A swimming pool with lounge chairs and a small building in the background.
A hotel room with a bed, a mirror, and a green wall.
A spacious lobby with a large clock, a fireplace, and a pool view.
A hotel reception area with a coffee machine, a microwave, and a potted plant.

7. Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South
0.3 mi from Mission Hope Cancer Center
United States
Chrisj
£75
includes taxes & fees
7 Oct - 8 Oct
Motel 6 Santa Maria, CA - South
An outdoor patio with tables and chairs, a bottle of wine, and a glass of red wine.
A two-story building with a sign reading "Wine Store Inn." It features a balcony on the upper floor and a covered outdoor seating area on the ground floor.
A modern lounge area with a wine rack, comfortable seating, and a TV displaying golf.
A modern bar area with a long counter, bar stools, and a wine display.

8. Wine Stone Inn

Wine Stone Inn
6.3 mi from Mission Hope Cancer Center
United States
DALLAS Cooper
£136
includes taxes & fees
27 Sept - 28 Sept
Wine Stone Inn
A dining table with a plate of food, a glass of white wine, and a bar area in the background.
An outdoor patio with a grill, seating, and a view of a building.
A modern kitchen with a dining area, a sofa, and a coffee machine.
A modern hotel room with a large bed, a desk with a chair, a television, and a kitchenette.

9. Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria
2.1 mi from Mission Hope Cancer Center
United States
Katrina
£126
includes taxes & fees
4 Oct - 5 Oct
Homewood Suites by Hilton Santa Maria
A modern hotel lobby with a long wooden reception desk, multiple bar stools, and pendant lighting.
A hotel with a parking lot, electric vehicle charging stations, and a covered entrance.
A rectangular indoor pool with clear blue water, surrounded by lounge chairs and a sunlit area with large windows.
A lobby with a stone wall, a large painting, a beige sofa, and a wooden chair.

10. Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria
2 mi from Mission Hope Cancer Center
United States
Zenny
£95
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites by Marriott Santa Maria
A modern hotel room with a kitchenette, a dining area, and a bedroom.
A covered outdoor patio with two barbecue grills, a concrete floor, and a metal fence.
A reception area with a wooden reception desk, a man and woman at the desk, a dog on a leash, and a luggage cart.
A kitchenette with shelves stocked with snacks, beverages, and a coffee machine.

11. Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG
2.1 mi from Mission Hope Cancer Center
United States
Leighanna
£96
includes taxes & fees
29 Sept - 30 Sept
Candlewood Suites Santa Maria by IHG
A sign for Solaire Inn & Suites with a clear view of the surrounding palm trees and a street in the background.
A kitchenette with a microwave, a small refrigerator, a chair, and a flat-screen TV mounted on the wall.
A hotel room with two beds, a window with blinds, a bedside table, and a wall-mounted air conditioner.
A wall with framed certificates and a vase of white roses.

12. Solaire Inn & Suites

Solaire Inn & Suites
2.3 mi from Mission Hope Cancer Center
United States
Eduardo
£48
includes taxes & fees
27 Sept - 28 Sept
Solaire Inn & Suites
A hotel reception area with a counter, a TV displaying news, framed pictures on the wall, and a sign indicating the hotel name 'motel 6'.
A motel with a swimming pool, multiple rooms, and a parking area.
A hotel room with two beds, a desk, a TV, a bathroom, and a nightstand with a phone.
A row of white front-loading washing machines in a laundry room with a plain wall and a sloped ceiling.

13. Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North
2.1 mi from Mission Hope Cancer Center
United States
Tracy
£50
includes taxes & fees
4 Oct - 5 Oct
Motel 6 Santa Maria, CA - North
A spacious lobby with a high ceiling, multiple seating areas, and a central bar.
A modern interior with seating areas, a high ceiling, and visible structural elements.
A hotel room with a large bed, a sliding glass door to a balcony, a wall-mounted artwork, and a bedside table with a lamp.
A hotel pool area with multiple levels of balconies, lounge chairs, and a clear blue pool.

14. Radisson Hotel Santa Maria

Radisson Hotel Santa Maria
4.2 mi from Mission Hope Cancer Center
United States
Teresa
£128
includes taxes & fees
4 Oct - 5 Oct
Radisson Hotel Santa Maria
A hotel room with a bed, a nightstand, a lamp, a window with curtains, and a radiator.
A bathroom with a wooden vanity, a mirror, and a toilet.
A Colonial Motel sign with a fountain and flower beds in front.
A modern office space with a wooden desk, a computer, and a vase of flowers.

15. Colonial Motel

Colonial Motel
2.1 mi from Mission Hope Cancer Center
United States
Darren
£63
includes taxes & fees
25 Oct - 26 Oct
Colonial Motel
View all properties

Compare popular hotels close to Mission Hope Cancer Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A restaurant with long wooden tables and booths, hanging plants, and a decorative ceiling.
Best Western Plus Big America
8.8
Excellent
1,001 reviews
View
A hotel room with a large flat-screen TV mounted on the wall, a bedside table with a lamp, a mirror, and a bed.
Hotel Avanti
8.6
Excellent
479 reviews
View
A courtyard with a fountain, palm trees, and string lights.
Historic Santa Maria Inn
8.4
Very good
2,334 reviews
View
A hotel room with a bed, a wooden dresser, a desk with a chair, and a nightstand with a lamp.
Villa Motel
8.0
Very good
447 reviews
View
A hotel room with a bed, desk, TV, and ceiling fan.
Quality Inn & Suites Santa Maria
8.0
Very good
1,008 reviews
View

Top Mission Hope Cancer Center Hotel Reviews

Oxford Suites Pismo Beach

Oxford Suites Pismo Beach

8/10 Good
"We go here almost every summer. Such a quaint property. It’s dated but well kept and great staff! Awesome breakfast, lots of parking. Amazing happy hour. Very family friendly."
Glady 4-night trip
Posted 2 hours ago
Oxford Suites Pismo Beach
SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

10/10 Excellent
"We had a great stay the room and grounds we're clean the pool and hot tub we're great the beach was wonderful. The stairs to the beach we're a bit of a workout but we needed that anyway"
Becky 1-night trip
Posted 5 hours ago
SeaCrest OceanFront Hotel
Hampton Inn & Suites Arroyo Grande/Pismo Beach Area, CA

Hampton Inn & Suites Arroyo Grande/Pismo Beach Area, CA

10/10 Excellent
"Very clean room and friendly staff."
Bruno 1-night trip
Posted 6 hours ago
Hampton Inn & Suites Arroyo Grande/Pismo Beach Area, CA
Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria

10/10 Excellent
"Nice and clean"
REYNALDO 2-night trip
Posted 14 hours ago
Homewood Suites by Hilton Santa Maria
Aloha Inn

Aloha Inn

10/10 Excellent
"Clean"
Martin 1-night trip
Posted 1 day ago
Aloha Inn
Hotel Avanti

Hotel Avanti

8/10 Good
"Everything is great, except for the hanging barn doors. It feels really weird to use the bathroom with door gaps both sides!"
Phuong-Ha 1-night trip
Posted 2 days ago
Hotel Avanti
The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection

10/10 Excellent
"Complimentary wine bottle was a nice touch. The high ceilings made the room feel much larger. It was nice to see wooden floors instead of usual carpet. At night, super quiet and peaceful patio..looking out to beautiful greenery. Super close location to the Village, my kids enjoyed this hotel. Staff very friendly, we definitely would stay here again."
Alyssa 2-night trip
Posted 2 days ago
The Agrarian Hotel, BW Signature Collection
Days Inn by Wyndham Arroyo Grande/Pismo Beach

Days Inn by Wyndham Arroyo Grande/Pismo Beach

10/10 Excellent
"Great for a 1 night stay. Rooms are relatively updated."
Joseph 1-night trip
Posted 2 days ago
Days Inn by Wyndham Arroyo Grande/Pismo Beach
Solaire Inn & Suites

Solaire Inn & Suites

10/10 Excellent
"Todo excelente gracias"
Joel 1-night trip
Posted 2 days ago
Solaire Inn & Suites

Frequently asked questions

What's the area like around Mission Hope Cancer Center?
Mission Hope Cancer Center is located in a family-friendly area of Santa Maria known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 10 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mission Hope Cancer Center?
Historic Santa Maria Inn is one of the top choices for your stay based on our traveller data, and this hotel offers 2 bars and a restaurant. It's located 1.4 mi (2.2 km) from Mission Hope Cancer Center. Other good options within 5 miles include Villa Motel and Homewood Suites by Hilton Santa Maria.
How many hotels will I be able to find near Mission Hope Cancer Center?
Expedia has 10 hotels and other accommodation options within a mile from Mission Hope Cancer Center.
If I need to cancel the hotel reservation for my stay near Mission Hope Cancer Center, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Mission Hope Cancer Center.
What can I see and do near Mission Hope Cancer Center?
Study the collections at Santa Maria Valley Historical Society, Natural History Museum or Santa Maria Museum of Flight. You can enjoy live performances at Pacific Conservatory Theatre and Santa Maria Civic Theatre. Children's Resource & Referral (CRR) Discovery Museum, Rancho Bowl and Santa Maria Fairpark are fun stops for the whole family while you're in town.