Why should I book my Mesopotamia holiday with Expedia?

With excellent-value airfares, accommodation and car hire choices all in the same place, Expedia makes planning your Mesopotamia holiday a piece of cake. What's more, we can help you bundle your bookings into a package holiday so you can get even more savings. Choose from fabulous properties, add your flights and/or a hire car (and maybe also some exciting activities!) and score incredible prices. Need to cancel? Expedia offers a flexible cancellation policy for many reservations. To find out more, head over to our Customer Service Portal link .

When is the best time of year to holiday in Mesopotamia?

Mesopotamia is very popular in March, April and November. If you don't like big crowds and prefer a quieter pace, lock in your trip for June, July and August. With daytime average temperatures of 12ºC, July is the coolest period in Mesopotamia. The warmest time of year is January, when you can expect averages of 26ºC during the day. Whatever the temperature, you'll find loads to keep you entertained here.

What are the top hotels for my holiday in Mesopotamia?

Hotel Plaza and 11 Peyret Rent Aparts know how to make their guests feel welcome in Colon. If you also plan to stay in Parana, look up Hathor Concordia and Beautiful Brand New 2 Bedroom House with Garage . Both are top picks with travellers.

How do I get a cheap holiday to Mesopotamia?

Our Mesopotamia holidays mean plenty of savings for the savvy traveller. For the best deal, simply bundle your hotel, flights and activities. But bargain prices are only the start of your next epic adventure. Book with Expedia and and you'll have over 400 airlines and 321,000 hotel options worldwide to pick from. No matter your budget or style, there's a holiday here that's perfect for you. Learn more about how you can save money on your next holiday when you bundle your flight and hotel bookings with Expedia.

What should I do on my Mesopotamia holiday?

There are plenty of things to put on your travel agenda during your holiday in Mesopotamia. Termas de Federacion , Termas De Colón , Termas Del Ayui and Basilica Nuestra Senora De Itati are among the major attractions.

Do I need a visa for my Mesopotamia holiday?

Official government websites will have all the information you need on visa requirements, application procedures and necessary documentation. Your nationality and the purpose of your visit, whether it be for work or pleasure, will determine if you need a visa for Mesopotamia. Also be sure that your passport is up to date and has at least six months validity remaining beyond your return date. Finalise all your travel planning well in advance to avoid any last-minute surprises.

What should I wear on my Mesopotamia holiday?

Do some research into the types of things people in Mesopotamia wear, and maybe even look up style blogs for some fashion tips. Aim to create a versatile wardrobe full of pieces that suit your destination and show off your unique sense of style. The weather will dictate your choice of clothing, so check the forecast for the places you want to visit. Mesopotamia is at its warmest in January, with average daily temperatures of 26ºC. July is the coolest time of year here with the mercury hovering around 12ºC in the daytime.

What does an Expedia Mesopotamia holiday include?

Flights, car hires and hotels, or any combination of the three — it's your choice. Whether you're visiting Mesopotamia with the family or travelling with your friends, there's a package to match every budget and style. Once you've made your booking, why not add on some tours as well? Expedia has a wide range of properties in Mesopotamia, providing you with the freedom and flexibility to personalise your escape. Hotels and apartments are two of the most sought-after stays for visitors here.

Does Expedia offer Book Now, Pay Later Mesopotamia holidays?

Your bank balance shouldn't prevent you from going on holiday, so Expedia has devised a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a dream getaway without eating away at your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your break. Consider one of these flexible payment options: Pay monthly holidays : Klarna offers convenient monthly payment plans that work for all budget sizes, so you can jet away on that well-deserved holiday now. No-deposit holidays : If no upfront fee for your getaway makes pressing that "book now" button more stress-free, consider a no-deposit holiday plan with Klarna so you can Book Now, Pay Later!

Can I choose my airline with a Mesopotamia Expedia holiday?

Yes — and it's simple too. Expedia has access to more than 400 partner airlines globally. Our holiday packages give you the freedom to take your pick of available flights, hotels and activities that suit you.

Mesopotamia Holidays 2025

Things to do in Mesopotamia

Mesopotamia, Argentina, offers a delightful blend of entertainment, family fun, and adventure. Visitors can enjoy activities such as water parks, birdwatching, and hiking. Key experiences include guided tours to discover the ancient Mesopotamian heritage, participating in various rituals, and immersing oneself in cultural tours and festive processions that celebrate the region’s rich traditions.

Shopping

In Mesopotamia, you can explore the vibrant Mercado 4, where local artisans offer unique crafts. For a more modern experience, visit the Shopping del Sol, featuring a variety of shops and eateries. Both venues provide a delightful mix of traditional and contemporary Argentine gifts.

Recreation

In Mesopotamia, indulge in the serene atmosphere at the Yacu Wellness Spa, offering holistic therapies surrounded by lush landscapes. For relaxation, visit the Termas de Copahue, where natural thermal springs provide rejuvenating experiences, perfect for unwinding after a day of exploration.

Adventure

In Mesopotamia, explore the lush landscapes of the Ibera Wetlands, where you can kayak through waterways teeming with wildlife. Experience thrilling hikes in the Quebrada del Condorito, offering breathtaking views of the dramatic cliffs and diverse flora, perfect for adventure seekers.

Nightlife

The nightlife in Mesopotamia, Argentina, is vibrant and lively. Enjoy a cocktail at the chic Bar El Jardín, or immerse yourself in local culture at the lively Peñón del Águila, where traditional music fills the air, creating an unforgettable evening experience.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Mesopotamia

Mesopotamia, Argentina, is perfect for family-friendly and adventure-filled vacations, offering a variety of attractions such as national parks. Visitors can enjoy outdoor activities while exploring the rich history of ancient Mesopotamia, including its numerous gods and fascinating festivals. Whether you're seeking adventure or scenic beauty, Mesopotamia has something to delight every traveller.

Portal Carambola: This stunning national park, located 22.5km from Mesopotamia, offers thrilling adventures amidst breathtaking scenery. Enjoy outdoor activities while immersing yourself in the natural beauty and vibrant wildlife of the region.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	80.1°F (26.700000000000003°C)	Light Rain	Sunny	Moderately High	Average
February	77.7°F (25.4°C)	Light Rain	Mostly Sunny
March	72.9°F (22.700000000000003°C)	Light Rain	Mostly Sunny	Moderately High	Average
April	66.7°F (19.3°C)	Light Rain	Mostly Sunny	Average	Average
May	59.5°F (15.3°C)	Light Rain	Mostly Sunny
June	60.1°F (15.6°C)	Light Rain	Mostly Sunny
July	53.4°F (11.9°C)	Light Rain	Mostly Sunny	Average	Slightly High
August	63.7°F (17.6°C)	Light Rain	Mostly Sunny	Average	Slightly High
September	60.6°F (15.9°C)	Light Rain	Mostly Sunny	Average	Average
October	65.8°F (18.8°C)	Light Rain	Mostly Sunny	Average	Average
November	72.3°F (22.4°C)	Light Rain	Sunny	Moderately High	Average
December	77.0°F (25.0°C)	Light Rain	Sunny	Average	Slightly High

Tips to save on your trip to Mesopotamia

Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Mesopotamia.
Consider traveling to Mesopotamia during the low season () for more affordable options.
Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.