Title: Mesopotamia Holidays 2025 from £969 | Expedia.co.uk [Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.co.uk/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mesopotamia Holidays from £969 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence ### Better together Save up to £335 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Packages with flights are ATOL protected ### Your Mesopotamia Holiday Book a holiday package to Mesopotamia and feel how exhilarating it is to travel just the way you like. If Corrientes is among your stops, you'll be amazed by its culture, nature and festivals. Your trip to Mesopotamia wouldn't be complete without experiencing some of its most well-known cities, starting with [Corrientes](https://www.expedia.co.uk/Corrientes.d6054203.Destination-Travel-Guides). A couple of the most popular attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. [Concordia](https://www.expedia.co.uk/Concordia.d892.Destination-Travel-Guides) is another favourite city with Mesopotamia travellers. Visitors to this exciting city enjoy Termas Del Ayui and Concordia Speedway. Quit dreaming and get packing, because your Mesopotamia holiday is only clicks away with Expedia. ## Top Mesopotamia Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Regal Pacific Buenos Aires](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246568/a11bbed3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Regal Pacific Buenos Aires El Centro £969 per person 23 Jan - 27 Jan found 16 hours ago Return direct flight included London (LHR) to Buenos Aires (EZE) 8.8/10 Excellent! (1,005 reviews) This is an excellent hotel in Buenos Aires "Microcentro". Good hotel and close by walking distance to Buenos Aires main attractions. Good place to stay also for business purposes. Reviewed on 23 Aug 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-23/2026-01-27/?FromAirport=LHR&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1246568&paandie=true&dealMarker=QT9_blIa0KDT9DydLWSQxgzgceDLlaTkjVkU7stX49vDEi2_WlFPtPu2gBqukYZF) ![Faena Hotel Buenos Aires](https://images.trvl-media.com/lodging/2000000/1060000/1052300/1052252/e6484222_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Faena Hotel Buenos Aires Puerto Madero £1,323 per person 23 Jan - 27 Jan found 16 hours ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9/10 Wonderful! (457 reviews) Good property. I was thinking more of it like the Faena in Miami FL. The windows in this hotel are very thin. You hear everything outside, cars driving, cars racing, car mufflers. Overall a good experience. Reviewed on 1 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-23/2026-01-27/?FromAirport=LHR&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1052252&paandie=true&dealMarker=sX0XMrugTB94HazPpYQqMyoHxAAdsAPaIdbF7Y2nyeW4HfBiNWIM-_S5qCk3nE8P) ![Mine Hotel Boutique](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/42cccf50_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mine Hotel Boutique Palermo £1,135 per person 23 Jan - 27 Jan found 16 hours ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9.6/10 Exceptional! (1,001 reviews) The Hotel Mine Boutique is wonderful! Very nice staff, terrific breakfast, lovely room. The only very slight negative was that to get late checkout cost $40. We would highly recommend the hotel. Reviewed on 27 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-23/2026-01-27/?FromAirport=LHR&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1794972&paandie=true&dealMarker=sX0XMrugTB94HazPpYQqMyoHxAAdsAPaIdbF7Y2nyeVuHWMcT_IpRTYL9RyQxLwZ) ![Libertad Hotel Buenos Aires](https://images.trvl-media.com/lodging/5000000/4130000/4122000/4121952/8b50fdd9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Libertad Hotel Buenos Aires Buenos Aires Central Business District £1,067 per person 23 Jan - 27 Jan found 16 hours ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9/10 Wonderful! (517 reviews) The streets surrounding the hotel were blocked off for road work. The hotel should inform guests that they will have to walk at least a block with their suitcases to access the hotel or to catch a cab. Reviewed on 29 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-23/2026-01-27/?FromAirport=LHR&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=4121952&paandie=true&dealMarker=sX0XMrugTB94HazPpYQqMyoHxAAdsAPaIdbF7Y2nyeXlaV8j_-_BD9LV26OezWNm) ![Miravida Soho Hotel & Wine Bar](https://images.trvl-media.com/lodging/11000000/10220000/10218400/10218330/79c084b9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Miravida Soho Hotel & Wine Bar Palermo £1,065 per person 23 Jan - 27 Jan found 16 hours ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9.4/10 Exceptional! (261 reviews) First wanted to say all the staff at the hotel were amazing, they really wanted to make sure you had a great stay. This is a small boutique hotel, there is a small reception area, bar/breakfast space and small courtyard. We stayed in 2 different rooms as we had a split stay. The duplex room No 7 needed a bit of attention, water damage on the bathroom ceiling should be fixed. The suite category room was better in my opinion No 3. Lots of restaurants to walk to and we felt safe. Reviewed on 22 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-23/2026-01-27/?FromAirport=LHR&Destination=EZE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=10218330&paandie=true&dealMarker=sX0XMrugTB94HazPpYQqMyoHxAAdsAPaIdbF7Y2nyeXJkGP7UKZMkxSnYjYz04or) ## Mesopotamia Holiday Packages Encounter a range of tropical vegetation and animals in the lush terrain of this area where you will find one of the world’s largest waterfalls. Mesopotamia is a vast green and tropical expanse that has some of Argentina’s most idyllic landmarks. It contains the world-famous [Iguazú Falls](https://www.expedia.co.uk/Iguazu-Falls-Puerto-Iguazu.d6171898.Attraction), which is among the widest and tallest waterfalls in the world. Travel around this lush area for its exotic animals and vegetation and small towns with thriving culture. The highlight of the region is the **Iguazú National Park**, which consists of tropical forests and the roaring waterfall that can be seen from the Brazilian and Argentine sides of the park. Wander through the forests to spot exotic creatures, such as tapirs, anteaters and ocelots. The town of **Puerto** **Iguazú** outside the park has many steak restaurants and the **Three Borders Mark**, which has a fountain and a view of the Brazilian and Paraguayan flanks of the river. Bring the kids to the **Hummingbird Garden (Jardin de los Picaflores)**. Travel south for a few hours by bus to reach the **Ibera Wetlands**, which contains extraordinary flooded forests. It is a maze of water networks stretching across an area of 3.2 million acres (1.3 million hectares) with fascinating animals roaming its wet fields. Nearby is **Posadas**, where you will find the San Roque González de Santa Cruz Bridge linking Argentina and Paraguay. At the southern end of the area is **Gualeguaychú**, which hosts a thriving carnival around the **Gualeguaychú Plaza San Martín** at the beginning of Lent. Listen to the Chamamé folk music of the area that blends Spanish guitar and accordion. Located in the northeastern region of Argentina, Mesopotamia lies on the borders with Paraguay and Brazil. It incorporates the provinces of [Entre Ríos](https://www.expedia.co.uk/Entre-Rios-Province.d6232337.Holidays-City-Breaks), [Corrientes](https://www.expedia.co.uk/Corrientes-Province.d6232362.Holidays-City-Breaks) and [Misiones](https://www.expedia.co.uk/Misiones-Province.d6232393.Holidays-City-Breaks). Fly to Cataratas del Iguazú International Airport and stay in the town of Puerto Iguazú during your trip to the falls. Get around the vast region by bus. Expect scorching summers with heavy rainfall and warm winters. Try the Argentine traditional hot beverage of mate, a herbal tea made from leaves from the yerba plant, which is mostly grown in this area. Mesopotamia is made up of fertile land with gushing cascades, exotic flora and fauna and intriguing towns. ## Mesopotamia Essential Information | Language | Spanish | | --- | --- | | Currency | Argentine pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Ministro Pistarini Intl. Airport (EZE) | ## Top hotels in Mesopotamia ![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Corrientes Hotel Av Costanera Juan Pablo II y Lavalle, Corrientes Fully refundableReserve now, pay when you stay £102 8 Nov - 9 Nov [](https://expedia.co.uk/Hotel-Search?startDate=08%2F11%2F2025&endDate=09%2F11%2F2025&selected=117154160&PinnedHotelID=117154160&HadPinnedHotel=true®ionId=6208836) ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### O2 Hotel Gualeguaychú 115 3 de Febrero, Gualeguaychú, Entre Ríos Fully refundableReserve now, pay when you stay £22 3 Nov - 4 Nov 7.6/10 Good! (62 reviews) Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. Reviewed on 2 Jan 2025 [](https://expedia.co.uk/Hotel-Search?startDate=03%2F11%2F2025&endDate=04%2F11%2F2025&selected=76459363&PinnedHotelID=76459363&HadPinnedHotel=true®ionId=6208836) ![Hotel y Spa Termas del Este](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/459986e2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel y Spa Termas del Este Presidente Raúl alfonsín 877, Federacion Fully refundableReserve now, pay when you stay 8.4/10 Very Good! (12 reviews) good for a 1 night stay Reviewed on 16 Aug 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=33346911&PinnedHotelID=33346911&HadPinnedHotel=true®ionId=6208836) [](https://expedia.co.uk/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=33346911&PinnedHotelID=33346911&HadPinnedHotel=true®ionId=6208836) [See all 492 properties in Mesopotamia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=6208836) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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If you've already reserved your flight to Mesopotamia, make use of our [Customer Service Portal](https://www.expedia.co.uk/service/?langId=1033). It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps. ### What's the best way to find cheap flights to Mesopotamia that have flexible change policies? > Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia. ### What are some of the general tips for travellers to Mesopotamia during the COVID-19 outbreak? > If it's your first time travelling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one: > > - Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing. > - Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity. > - Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection. > - You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening. > - Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening. > - Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings. ### Which airlines fly to Mesopotamia? > Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway. ### How can I find cheap tickets to Mesopotamia? > One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal. ### How much is a flight to Mesopotamia? > You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just . ### What are the most popular airports to fly into in Mesopotamia? > Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month. ### When is the cheapest time to fly to Mesopotamia? > Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays. ### How much is a plane ticket to Mesopotamia? > Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal. ### Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies? > In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples: > > - Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant. > - LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights. > - American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant. ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)