Title: Mesopotamia Holidays 2026 from £1,066 | Expedia.co.uk [Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.co.uk/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6208836/ca0c6990-9932-4f38-bee6-e89ce7080803.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mesopotamia Holidays from £1,066 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ### Your Mesopotamia Holiday Book a holiday package to Mesopotamia and feel how exhilarating it is to travel just the way you like. If Corrientes is among your stops, you'll be amazed by its culture, nature and festivals. Your trip to Mesopotamia wouldn't be complete without experiencing some of its most well-known cities, starting with [Corrientes](https://www.expedia.co.uk/Corrientes.d6054203.Destination-Travel-Guides). A couple of the most popular attractions here include Museo de Artesanías Tradicionales Folclóricas and Casinos del Litoral. [Concordia](https://www.expedia.co.uk/Concordia.d892.Destination-Travel-Guides) is another favourite city with Mesopotamia travellers. Visitors to this exciting city enjoy Termas Del Ayui and Concordia Speedway. Quit dreaming and get packing, because your Mesopotamia holiday is only clicks away with Expedia. ## Top Mesopotamia Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Regal Pacific Buenos Aires](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246568/a11bbed3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Regal Pacific Buenos Aires Microcentro £1,066 per person 10 Mar - 14 Mar found 1 day ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9/10 Wonderful! (1,000 reviews) Problems wc/bathroom that we noticed after unpacking already .They fixed after 4hrs . Stay at pool ,but eventuly we had to step out /couldn stay because the life guard was going out for lunch .Fine but they could replace him with someone else for those minuts lunch break .Otherwise great hotel ,location, Reviewed on 9 Jan 2026 ![Mio Buenos Aires](https://images.trvl-media.com/lodging/5000000/4270000/4260900/4260897/c2d0cfcb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mio Buenos Aires Recoleta £1,281 per person 10 Mar - 14 Mar found 1 day ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9.4/10 Exceptional! (566 reviews) The front desk people were very helpful! They called an Uber for us when we left our valuables in the safe of another hotel in Buenos Aires and kept our bags safe until we could check in! Thank you, Mio! Very friendly and helpful staff. Reviewed on 27 Jan 2026 ![Faena Hotel Buenos Aires](https://images.trvl-media.com/lodging/2000000/1060000/1052300/1052252/e6484222_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Faena Hotel Buenos Aires Puerto Madero £1,888 per person 10 Mar - 14 Mar found 1 day ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9/10 Wonderful! (463 reviews) Staff and facility were great Reviewed on 19 Jan 2026 ![Casa Lucia Member of Melia Collection](https://images.trvl-media.com/lodging/96000000/95560000/95550400/95550354/f15dde32_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Lucia Member of Melia Collection El Centro £1,348 per person 10 Mar - 14 Mar found 1 day ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9.6/10 Exceptional! (68 reviews) This is a very well maintained and beautiful hotel in a safe and gorgeous part of Buenos Aires. We had a truly delightful 4-day stay in what felt like a home away from home. Reviewed on 27 Jan 2026 ![Palacio Duhau - Park Hyatt Buenos Aires](https://images.trvl-media.com/lodging/2000000/1340000/1339900/1339890/d2ef6501_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Palacio Duhau - Park Hyatt Buenos Aires Recoleta £2,241 per person 10 Mar - 14 Mar found 1 day ago Return direct flight included London (LHR) to Buenos Aires (EZE) 9.6/10 Exceptional! (457 reviews) Palacio Duhau is a beautiful hotel in one the nicest areas in Buenos Aires. The staff are friendly and very accommodating. The only complaint I have is the small quantity and choices of the buffet breakfast. The rooms are nice and spacious. I would definitely stay here again. Reviewed on 27 Jan 2026 ### Things to do in Mesopotamia In Mesopotamia, Argentina, indulge in birdwatching and hiking amidst stunning wildlife. Explore the fascinating ancient Mesopotamian culture through specialised tours, where you can witness various rituals and partake in cultural experiences. Don't miss the vibrant festive processions that showcase the region's rich traditions, making your visit both enlightening and entertaining. **Shopping** In Mesopotamia, visit the Shopping Sur to discover a variety of local crafts and souvenirs. The nearby Alto Avellaneda Shopping offers a mix of international brands and dining options. Explore local markets for unique gifts that capture the region's culture and charm. **Recreation** Mesopotamia Wellness Retreat offers rejuvenating spa treatments in a tranquil setting, surrounded by lush landscapes. Engage in yoga sessions by the river, and indulge in organic cuisine sourced from local farms, promoting both relaxation and healthy living during your stay. **Adventure** In Mesopotamia, explore the lush landscapes of the Iberá Wetlands, where you can kayak through vibrant ecosystems teeming with wildlife. Experience thrilling boat rides on the Paraná River, and hike the captivating trails of the Quebrada de los Cóndores to witness stunning vistas and unique birdwatching opportunities. **Nightlife** In Mesopotamia, Argentina, experience vibrant nightlife at lively bars and clubs in Posadas. Visit hotspots like La Ronda and La Vida, where you can enjoy live music, regional cocktails, and dance until dawn. The atmosphere is warm, welcoming, and filled with the rhythm of Latin beats. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Find the best attractions near Mesopotamia Mesopotamia, Argentina, offers a wealth of adventure and scenic beauty, particularly through its national parks. Visitors can immerse themselves in the rich history of the ancient Mesopotamians, exploring their numerous gods and the vibrant festivals that once celebrated their culture. Whether you seek outdoor experiences or a glimpse into the past, Mesopotamia promises an enriching getaway for all types of travellers. - **Portal Carambola:** A stunning national park 22.5km from Mesopotamia, offering breathtaking scenery, outdoor adventures, and a chance to immerse yourself in nature's beauty. ### Best time to go to Mesopotamia The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 80.1°F (26.700000000000003°C) | Light Rain | Sunny | Moderately High | Average | | February | 77.7°F (25.4°C) | Light Rain | Mostly Sunny | | | | March | 72.9°F (22.700000000000003°C) | Light Rain | Mostly Sunny | Moderately High | Average | | April | 66.7°F (19.3°C) | Light Rain | Mostly Sunny | Average | Average | | May | 59.5°F (15.3°C) | Light Rain | Mostly Sunny | | | | June | 60.1°F (15.6°C) | Light Rain | Mostly Sunny | | | | July | 53.4°F (11.9°C) | Light Rain | Mostly Sunny | Average | Slightly High | | August | 63.7°F (17.6°C) | Light Rain | Mostly Sunny | Average | Slightly High | | September | 60.6°F (15.9°C) | Light Rain | Mostly Sunny | Average | Average | | October | 65.8°F (18.8°C) | Light Rain | Mostly Sunny | Average | Average | | November | 72.3°F (22.4°C) | Light Rain | Sunny | Moderately High | Average | | December | 77.0°F (25.0°C) | Light Rain | Sunny | Average | Slightly High | ### Tips to save on your trip to Mesopotamia - Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings. - Consider traveling to Mesopotamia during the low season () for more affordable options. - Use the *Price per traveler* filter on Expedia to find a package deal that suits your budget. - Check the *VIP Access properties* filter to discover outstanding hotels with added member perks at select properties. ## Mesopotamia Holiday Packages Encounter a range of tropical vegetation and animals in the lush terrain of this area where you will find one of the world’s largest waterfalls. Mesopotamia is a vast green and tropical expanse that has some of Argentina’s most idyllic landmarks. It contains the world-famous [Iguazú Falls](https://www.expedia.co.uk/Iguazu-Falls-Puerto-Iguazu.d6171898.Attraction), which is among the widest and tallest waterfalls in the world. Travel around this lush area for its exotic animals and vegetation and small towns with thriving culture. The highlight of the region is the **Iguazú National Park**, which consists of tropical forests and the roaring waterfall that can be seen from the Brazilian and Argentine sides of the park. Wander through the forests to spot exotic creatures, such as tapirs, anteaters and ocelots. The town of **Puerto** **Iguazú** outside the park has many steak restaurants and the **Three Borders Mark**, which has a fountain and a view of the Brazilian and Paraguayan flanks of the river. Bring the kids to the **Hummingbird Garden (Jardin de los Picaflores)**. Travel south for a few hours by bus to reach the **Ibera Wetlands**, which contains extraordinary flooded forests. It is a maze of water networks stretching across an area of 3.2 million acres (1.3 million hectares) with fascinating animals roaming its wet fields. Nearby is **Posadas**, where you will find the San Roque González de Santa Cruz Bridge linking Argentina and Paraguay. At the southern end of the area is **Gualeguaychú**, which hosts a thriving carnival around the **Gualeguaychú Plaza San Martín** at the beginning of Lent. Listen to the Chamamé folk music of the area that blends Spanish guitar and accordion. Located in the northeastern region of Argentina, Mesopotamia lies on the borders with Paraguay and Brazil. It incorporates the provinces of [Entre Ríos](https://www.expedia.co.uk/Entre-Rios-Province.d6232337.Holidays-City-Breaks), [Corrientes](https://www.expedia.co.uk/Corrientes-Province.d6232362.Holidays-City-Breaks) and [Misiones](https://www.expedia.co.uk/Misiones-Province.d6232393.Holidays-City-Breaks). Fly to Cataratas del Iguazú International Airport and stay in the town of Puerto Iguazú during your trip to the falls. Get around the vast region by bus. Expect scorching summers with heavy rainfall and warm winters. Try the Argentine traditional hot beverage of mate, a herbal tea made from leaves from the yerba plant, which is mostly grown in this area. Mesopotamia is made up of fertile land with gushing cascades, exotic flora and fauna and intriguing towns. ## Mesopotamia Essential Information | Language | Spanish | | --------------- | -------------------------------------- | | Currency | Argentine pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Ministro Pistarini Intl. Airport (EZE) | ## Top hotels in Mesopotamia ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### O2 Hotel Gualeguaychú 115 3 de Febrero Gualeguaychú Entre Ríos Fully refundableReserve now, pay when you stay £31 5 Feb - 6 Feb 7.6/10 Good! (69 reviews) La limpieza de los cuartos necesita mejorar. También agregar servicios básicos como TV y teléfono en los cuartos Reviewed on 12 Mar 2025 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F02%2F2026&endDate=06%2F02%2F2026&selected=76459363&PinnedHotelID=76459363&HadPinnedHotel=true®ionId=6208836) ![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Corrientes Hotel Av Costanera Juan Pablo II y Lavalle Corrientes Fully refundableReserve now, pay when you stay £97 5 Feb - 6 Feb 9.8/10 Exceptional! (20 reviews) Excelente Reviewed on 21 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F02%2F2026&endDate=06%2F02%2F2026&selected=117154160&PinnedHotelID=117154160&HadPinnedHotel=true®ionId=6208836) ![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hathor Concordia Ruta Nacional 14-km 264.5 Concordia Entre Rios Fully refundableReserve now, pay when you stay 8.6/10 Excellent! (364 reviews) The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional". Reviewed on 5 Dec 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=4668235&PinnedHotelID=4668235&HadPinnedHotel=true®ionId=6208836) [](https://expedia.co.uk/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=4668235&PinnedHotelID=4668235&HadPinnedHotel=true®ionId=6208836) [See all 497 properties in Mesopotamia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=30%2F01%2F2026&endDate=31%2F01%2F2026®ionId=6208836) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Frequently asked questions ### Can I cancel my flight booking to Mesopotamia due to COVID-19? ### What's the best way to find cheap flights to Mesopotamia that have flexible change policies? ### What are some of the general tips for travellers to Mesopotamia during the COVID-19 outbreak? > - Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing. > - Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity. > - Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection. > - You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening. > - Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening. > - Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings. ### Which airlines fly to Mesopotamia? ### How can I find cheap tickets to Mesopotamia? ### How much is a flight to Mesopotamia? ### What are the most popular airports to fly into in Mesopotamia? ### When is the cheapest time to fly to Mesopotamia? ### How much is a plane ticket to Mesopotamia? ### Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies? > - Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant. > - LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights. > - American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant. ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app