Title: Hotels in Mesopotamia - Best Mesopotamia Hotels from £25 - Fully Refundable Options - Expedia.co.uk [Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6208836)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide)[Mesopotamia Holidays](https://expedia.co.uk/Mesopotamia.d6208836.Holidays-City-Breaks) ![Iguazu Falls showing a cascade](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mesopotamia Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&lodging=APART_HOTEL) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&lodging=APARTMENT) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Mesopotamia%2C+Argentina®ionId=6208836&latLong=-30.337161%2C-58.464548&adults=2&startDate=2026-03-19&d1=2026-03-19&endDate=2026-03-21&d2=2026-03-21&amenities=HOT_TUB) ## Check prices for these dates Tonight [5 Mar - 6 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-05&endDate=2026-03-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [6 Mar - 7 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-06&endDate=2026-03-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesopotamia hotels ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/0e5b5ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/8d2994c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/9f96608b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mayim Hotel Termal & SPA [](https://www.expedia.co.uk/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) Concordia 9.2/10 Wonderful (7 reviews) "Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catalina £69 15 Mar - 16 Mar [](https://www.expedia.co.uk/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/5a0bc70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/8be36161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/b05a90aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/3c95eafc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Regina Lodge [](https://www.expedia.co.uk/Municipo-De-Itati-Hotels-La-Regina-Lodge.h120713176.Hotel-Information) Municipo de Itati 10/10 Exceptional (1 review) "Excelente pousada, piscina fantástica com visual do rio" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Marcos £57 17 Mar - 18 Mar [](https://www.expedia.co.uk/Municipo-De-Itati-Hotels-La-Regina-Lodge.h120713176.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/a0b30be4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room, River View | In-room safe, free WiFi](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/7faffc8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/8965968d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/w1021h683x3y0-b40ed89a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Turismo Hotel Casino [](https://www.expedia.co.uk/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information) Corrientes 8.0/10 Very good (4 reviews) "Boa infraestrutura, e localização!" ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) D. Omar £83 8 Mar - 9 Mar [](https://www.expedia.co.uk/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/cfc48717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/03c0216a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/dcc1a9bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Corrientes Hotel [](https://www.expedia.co.uk/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) Corrientes 10/10 Exceptional (22 reviews) "Fantastic stay. Room was immaculate and hotel staff were very friendly and helpful. Great pool and beds were super comfortable." ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Marcus £107 13 Mar - 14 Mar [](https://www.expedia.co.uk/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/b3e275d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room (VIP) | Jetted bathtub](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/ea0ac718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/216c6bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Bungalow, 1 Bedroom | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363214/7441aa6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bungalows Mexico [](https://www.expedia.co.uk/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) Concepción del Uruguay 8.8/10 Excellent (12 reviews) "Local estava limpo, a cama é ótima, mas o banheiro a água n esquentava. O atendimento foi bom, são atenciosos. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Eduardo £40 13 Mar - 14 Mar [](https://www.expedia.co.uk/Concepcion-Del-Uruguay-Hotels-Bungalows-Mexico.h15363214.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/60e3bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7eec541e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7876fff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/750a674d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Valle Termal Resort [](https://www.expedia.co.uk/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) Federacion 9.2/10 Wonderful (94 reviews) "La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fernando £71 7 Mar - 8 Mar [](https://www.expedia.co.uk/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/388c5726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/ff681a63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c114ee3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803582/c058d200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Alondra Casa De Huéspedes [](https://www.expedia.co.uk/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) Corrientes 9.2/10 Wonderful (68 reviews) "Todo excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Arturo Oscar £68 8 Mar - 9 Mar [](https://www.expedia.co.uk/Corrientes-Hotels-La-Alondra-Casa-De-Huespedes.h2803582.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/98d1ea7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/fe749255.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually furnished, desk, blackout curtains](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/7d9efe4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/37000000/36910000/36908500/36908421/3843845d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Rio [](https://www.expedia.co.uk/Chajari-Hotels-Hotel-Rio.h36908421.Hotel-Information) Chajarí 8.8/10 Excellent (11 reviews) "Lindo hotel, moderno, limpio, buena atencion, sumaria opciones saladas en el desayuno, como huevos revueltos." ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) SANTIAGO £59 8 Mar - 9 Mar [](https://www.expedia.co.uk/Chajari-Hotels-Hotel-Rio.h36908421.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/5e4aef5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rollaway beds, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/5b08b016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/cbc5acd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room | Rollaway beds, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/39000000/38310000/38300200/38300196/8e6becd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada Che Teindy [](https://www.expedia.co.uk/Colonia-Carlos-Pellegrini-Hotels-Posada-Che-Teindy.h38300196.Hotel-Information) Colonia Carlos Pellegrini £79 7 Mar - 8 Mar [](https://www.expedia.co.uk/Colonia-Carlos-Pellegrini-Hotels-Posada-Che-Teindy.h38300196.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/fb045420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/e9b4b524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Triple Suite + Trundle Bed (4 people) | Premium bedding, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/4eedefaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/5000000/4950000/4947900/4947848/b6d8eda3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donsuites Apart Hotel [](https://www.expedia.co.uk/Corrientes-Hotels-Donsuites-Apart-Hotel.h4947848.Hotel-Information) Corrientes 8.6/10 Excellent (106 reviews) "Loved this place, super clean, and the staff were very nice and helpful😍" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nora £43 8 Mar - 9 Mar [](https://www.expedia.co.uk/Corrientes-Hotels-Donsuites-Apart-Hotel.h4947848.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/69183496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/bbc0cb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/529e58c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/112000000/111300000/111298300/111298221/fb150aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Estancia Iberá [](https://www.expedia.co.uk/Mercedes-Hotels-Estancia-Ibera.h111298221.Hotel-Information) Mercedes 10/10 Exceptional (1 review) "we had a wonderful experience the staff was very friendly and helpful and took us out on lots of activities and we saw an amazing amount of wildlife in a very short period of time. The place is very beautiful and tranquil. I would highly recommend it and give it five stars. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) orit £139 24 Mar - 25 Mar [](https://www.expedia.co.uk/Mercedes-Hotels-Estancia-Ibera.h111298221.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/71c980b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathrobes, towels, toilet paper](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/1f6de405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/286a4e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/115000000/114600000/114592800/114592704/f712d971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nandereta Lodge [](https://www.expedia.co.uk/Colonia-Carlos-Pellegrini-Hotels-Nandereta-Lodge.h114592704.Hotel-Information) Colonia Carlos Pellegrini £213 7 Mar - 8 Mar [](https://www.expedia.co.uk/Colonia-Carlos-Pellegrini-Hotels-Nandereta-Lodge.h114592704.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e90b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/dd41bc20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/5cbe2a6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/fc0680d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Spa Termas del Este [](https://www.expedia.co.uk/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) Federacion 8.6/10 Excellent (13 reviews) "good for a 1 night stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chase [](https://www.expedia.co.uk/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) ![Executive Apartment | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/6427ef82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/aa85566a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City Apartment | Living area | 40-inch LED TV with cable channels, Netflix, streaming services](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/f34322b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Duplex | Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/960ad1f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Agustín 1 Apart [](https://www.expedia.co.uk/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) Parana 8.8/10 Excellent (5 reviews) "Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Jose rodrigo kallas £40 8 Mar - 9 Mar [](https://www.expedia.co.uk/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/11027249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LED TV](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/5adfed6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/f479bf8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88090000/88087500/88087470/ba4b5c63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Complejo La Loma [](https://www.expedia.co.uk/Federacion-Hotels-Complejo-La-Loma.h88087470.Hotel-Information) Federacion 8.0/10 Very good (5 reviews) "Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple... ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Logan [](https://www.expedia.co.uk/Federacion-Hotels-Complejo-La-Loma.h88087470.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/09dbf00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/a2d4eb00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/c1286a77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Intersur Colon [](https://www.expedia.co.uk/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information) Colón 9.0/10 Wonderful (7 reviews) "Is ok " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla £74 8 Mar - 9 Mar [](https://www.expedia.co.uk/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information) ![2 bedrooms, hypo-allergenic bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/8a2a257a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area | 32-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/758c5263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Private kitchen | Full-sized fridge, oven, stovetop, rice cooker](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/69bd66ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/f0f7bd93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Totoras Apart Federacion [](https://www.expedia.co.uk/Federacion-Hotels-Totoras-Apart-Federacion.h33341429.Hotel-Information) Federacion 7.4/10 Good (27 reviews) "Todo perfecto!!! " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Gabriel [](https://www.expedia.co.uk/Federacion-Hotels-Totoras-Apart-Federacion.h33341429.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/6a6d02f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/908e21a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/f4e90853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/96c06c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maran Suites & Towers - Hotel & Spa [](https://www.expedia.co.uk/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) Parana 9.0/10 Wonderful (32 reviews) "Great location and friendly, accommodating staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £86 10 Mar - 11 Mar [](https://www.expedia.co.uk/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/dbe6098c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/86b52c66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/3ea31922.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/759ad5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### O2 Hotel Gualeguaychú [](https://www.expedia.co.uk/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) Gualeguaychú 7.6/10 Good (76 reviews) "Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Esteban £30 9 Mar - 10 Mar [](https://www.expedia.co.uk/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/a0cc5957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/96c73453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/c45620e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, body treatments, hot stone massages, facials](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/ef76fc3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Costarenas Hotel & Spa [](https://www.expedia.co.uk/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) Colon 8.6/10 Excellent (60 reviews) "spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning" ![Argentina](https://a.travel-assets.com/egds/marks/flags/ar.svg) Lisette £88 7 Mar - 8 Mar [](https://www.expedia.co.uk/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-20&endDate=2026-03-21®ionId=6208836&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_SPRING_PROMO_6208836) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6208836.Travel-Guide-Hotels) ## Stay near popular Mesopotamia attractions ![Punta San Sebastian, Corrientes, Costanera Corrientes](https://images.trvl-media.com/place/553248621532463961/5eccf4f4-bdb0-4368-8beb-0fffd1c8eab0.jpg) ### Costanera de Corrientes Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532463961) ![Parque Nacional El Palmar, Entre Rios, Argentina.](https://images.trvl-media.com/place/6096826/3ac30eef-b699-482d-95ce-e991c872d599.jpg) ### El Palmar National Park Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6096826) ![Parroquia Nuestra Señora de Itati](https://images.trvl-media.com/place/553248621532463967/dcc3f703-5a3b-46d8-99a7-83b2e87b8ea0.jpg) ### Basilica Nuestra Senora De Itati Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532463967) ### Termas de Federacion Bring the children to Termas de Federacion and enjoy this exciting theme park in Federacion. Stroll along the beaches or discover the area's waterfalls. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532463682) ### Isla Cambacua Beach Why not spend a lazy afternoon at Isla Cambacua Beach during your trip to Concepción del Uruguay? Experience the area's art scene and museums. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635974793609) ### Termas De Colón Enjoy an outing to Termas De Colón during your stay in Colon. Discover the area's theatre scene and spas. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635939591385) ### Corsódromo You can find out about the history of Gualeguaychú with a stop at Corsódromo. Discover the area's museums and spas. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532374259) ### Termas Concepcion Entrerios Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this theme park in Concepción del Uruguay. Experience the area's art scene and museums. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532463656) ## Learn more about Mesopotamia The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration. [See all hotels in Mesopotamia](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-20&endDate=2026-03-21&adults=2®ionId=6208836) ![Iguazu Falls showing a cascade](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Mesopotamia Hotel Reviews ![Holiday Inn Express Rosario by IHG](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/7aadefa1_y.jpg) ### Holiday Inn Express Rosario by IHG 10/10 Excellent "This hotel is a bargain. The rooms are big and comfortable, the staff friendly and helpful and the breakfast delicious. It has a number of cafes and convenience stores close by. " [](https://expedia.co.uk/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information) ![Holiday Inn Rosario by IHG](https://images.trvl-media.com/lodging/1000000/580000/570400/570357/08f67295_y.jpg) ### Holiday Inn Rosario by IHG 8/10 Good "frienly and competent staff speaking English. room was fine" [](https://expedia.co.uk/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information) ![Casa del Árbol Hostel](https://images.trvl-media.com/lodging/37000000/36660000/36653400/36653372/a1bc361e_y.jpg) ### Casa del Árbol Hostel 2/10 Terrible "La plataforma por.donde contrate te reserva aunque no haya lugar en el hostel Un desastre todo. No tienen verguenza. Poco serio " [](https://expedia.co.uk/Concepcion-Del-Uruguay-Hotels-Casa-Del-Arbol.h36653372.Hotel-Information) ![Marriott Corrientes Hotel](https://images.trvl-media.com/lodging/118000000/117160000/117154200/117154160/45830686_y.jpg) ### Marriott Corrientes Hotel 10/10 Excellent "Fantastic stay. Room was immaculate and hotel staff were very friendly and helpful. Great pool and beds were super comfortable." [](https://expedia.co.uk/Corrientes-Hotels-Marriott-Corrientes-Hotel.h117154160.Hotel-Information) ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/dbe6098c_y.jpg) ### O2 Hotel Gualeguaychú 4/10 Poor "Si un huesped pregunta si se olvida algo en la habitacion tener la deliquicadesa de contestar por eso la calificaccion no me volveria a quedar " [](https://expedia.co.uk/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg) ### Hathor Concordia 6/10 Okay "AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road." [](https://expedia.co.uk/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Club Valle Termal Resort](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/60e3bf31_y.jpg) ### Club Valle Termal Resort 10/10 Excellent "La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto." [](https://expedia.co.uk/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Mayim Hotel Termal & SPA](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/0e5b5ce6_y.jpg) ### Mayim Hotel Termal & SPA 8/10 Good "Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación " [](https://expedia.co.uk/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) ## More cheap stays in Mesopotamia ![Como en casa](https://images.trvl-media.com/lodging/22000000/21480000/21476400/21476350/8ae7da40_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Como en casa San Luis 948 8B Rosario Santa Fe £25 17 Mar - 18 Mar 8.4/10 Very Good! (7 reviews) [](https://expedia.co.uk/Rosario-Hotels-Como-En-Casa.h21476350.Hotel-Information) ![O2 Hotel Gualeguaychú](https://images.trvl-media.com/lodging/77000000/76460000/76459400/76459363/dbe6098c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### O2 Hotel Gualeguaychú 115 3 de Febrero Gualeguaychú Entre Ríos £30 9 Mar - 10 Mar 7.6/10 Good! (76 reviews) [](https://expedia.co.uk/Gualeguaychu-Hotels-O2-Gualeguaychu.h76459363.Hotel-Information) ![Carat Apart Boutique](https://images.trvl-media.com/lodging/24000000/23970000/23963300/23963290/70523b6d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Carat Apart Boutique Montevideo 1552 Rosario Santa Fe £51 31 Mar - 1 Apr 9.4/10 Exceptional! (54 reviews) [](https://expedia.co.uk/Rosario-Hotels-Carat-Apart-Boutique.h23963290.Hotel-Information) ![Turismo Hotel Casino](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/62287b79_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Turismo Hotel Casino 650 Entre Ríos Corrientes Corrientes £83 8 Mar - 9 Mar 8/10 Very Good! (4 reviews) [](https://expedia.co.uk/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information) ![Hotel Casino Rio Uruguay](https://images.trvl-media.com/lodging/123000000/122660000/122659600/122659562/bb78e4e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Casino Rio Uruguay RN117 Paso de los Libres Corrientes [Get rates](https://expedia.co.uk/Hotel-Search?startDate=20%2F03%2F2026&endDate=21%2F03%2F2026&selected=122659562&PinnedHotelID=122659562&HadPinnedHotel=true®ionId=6208836) 10/10 Exceptional! (1 review) [](https://expedia.co.uk/Paso-De-Los-Libres-Hotels-Hotel-Casino-Rio-Uruguay.h122659562.Hotel-Information) ![Apart Hotel Las Violetas](https://images.trvl-media.com/lodging/92000000/91280000/91272000/91271956/0b3e9773_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apart Hotel Las Violetas Barrio del Lago Candelaria Misiones [Get rates](https://expedia.co.uk/Hotel-Search?startDate=20%2F03%2F2026&endDate=21%2F03%2F2026&selected=91271956&PinnedHotelID=91271956&HadPinnedHotel=true®ionId=6208836) [](https://expedia.co.uk/Candelaria-Hotels-Apart-Hotel-Las-Violetas.h91271956.Hotel-Information) ## Hotels in Mesopotamia with star rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 1 properties [](https://expedia.co.uk/5Star-Mesopotamia-Hotels.s50-0-d6208836.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 20 properties [](https://expedia.co.uk/4Star-Mesopotamia-Hotels.s40-0-d6208836.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 152 properties [](https://expedia.co.uk/3Star-Mesopotamia-Hotels.s30-0-d6208836.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 146 properties [](https://expedia.co.uk/2Star-Mesopotamia-Hotels.s20-0-d6208836.Travel-Guide-Filter-Hotels) ## Find out more about Mesopotamia ### Top reasons to visit Mesopotamia - **Stunning Natural Landscapes:** Mesopotamia boasts breathtaking scenery ideal for outdoor activities such as hiking and birdwatching. - **Family-Friendly Entertainment:** Enjoy exciting water parks and various adventure activities perfect for all ages. - **Cultural Immersion:** Experience the vibrant local culture through events like the lively Akitu celebration. - **Guided Tours:** Explore the region's rich heritage and natural beauty with a range of informative guided tours. - **Diverse Accommodation:** A variety of hotels, from budget-friendly to top-rated, cater to every traveller's needs. ### Find great hotels near Mesopotamia Explore the charming region of Mesopotamia, Argentina, where a variety of hotels await to provide you with a memorable family vacation experience. From budget-friendly options to top-rated establishments like the Astoria Hotel, you'll find accommodations that cater to every traveller's needs. With an abundance of reviews and insights available, planning your stay in this beautiful area has never been easier. - **[El Tránsito Hotel Boutique: ](https://www.expedia.co.uk/Concepcion-Hotels-Hotel-Boutique-El-Transito.h41507004.Hotel-Information)** This charming 3.5-star hotel is perfect for families seeking a delightful getaway near Mesopotamia. Located 11.2km from the area, it offers a warm, inviting atmosphere complemented by child-friendly amenities such as free cribs, an arcade game room, and a children's pool. Guests appreciate the thoughtful services tailored for families, ensuring a memorable vacation experience for both parents and children alike. With its focus on comfort and family enjoyment, El Tránsito Hotel Boutique is an excellent choice for your stay in Argentina. ### Where to stay near Mesopotamia Mesopotamia, Argentina, offers a delightful blend of adventure and relaxation for families and couples alike. Explore stunning beach resorts along its picturesque coastline, where you can enjoy outdoor activities and breathtaking scenery. Perfect for skiing enthusiasts, the region also boasts kilometres of pristine slopes. Whether you're seeking a romantic getaway or an action-packed holiday, Mesopotamia's charm and vibrant atmosphere make it an ideal destination for every traveller. - **[Concepción: ](https://www.expedia.co.uk/Concepcion-Hotels.d553248635924012399.Travel-Guide-Hotels)** Nestled 13.7km from Mesopotamia, Concepción is a vibrant city offering a myriad of outdoor adventures and stunning scenery. Visitors flock here year-round, with peak times in April, July, and September. The city is a gateway to various natural parks and a national state park, making it an ideal destination for nature enthusiasts and those seeking adventure. Expect to immerse yourself in the great outdoors, whether it's hiking, bird watching, or simply enjoying the breathtaking landscapes that surround you. - **[Mercedes: ](https://www.expedia.co.uk/Mercedes-Hotels.d6338887.Travel-Guide-Hotels)** Located 19.3km from Mesopotamia, Mercedes is a charming city perfect for families and adventure seekers alike. With visitor numbers peaking in July and the festive months of December to January, this location offers a variety of outdoor activities, including a fantastic water park and a scenic golf course. The proximity to a national state park and a theme park ensures that there's something for everyone to enjoy, whether it's a thrilling day at the park or a relaxing afternoon on the greens. - **Uguay:** Just 10.6km from Mesopotamia, Uguay is a quaint village known for its serene charm and natural beauty. Although visitor numbers fluctuate throughout the year, peaking in January, March, and August, Uguay remains a peaceful retreat. Nature lovers will appreciate the nearby natural parks, perfect for leisurely walks and wildlife observation. This village is an ideal spot for those looking to escape the hustle and bustle of city life while still being close enough to explore the vibrant surrounding areas. ### Things to do in Mesopotamia Mesopotamia, Argentina, is an excellent destination for family-friendly adventures, offering thrilling activities such as visiting a water park, birdwatching, and hiking. For a seamless experience, be sure to utilise the local tour desk, which can help you explore the area's attractions. With its blend of entertainment and outdoor pursuits, Mesopotamia promises an enjoyable holiday for all visitors. **Shopping** In Mesopotamia, visit the local markets for unique handicrafts and traditional gifts. If you're up for a drive, head to Shopping Abasto in Concordia, where you'll find a variety of shops and dining options, or explore the extensive offerings at Shopping Norte in Posadas. **Recreation** Mesopotamia Wellness Retreat offers rejuvenating spa treatments amidst lush landscapes, perfect for relaxation. Engage in yoga sessions surrounded by nature or explore tranquil walking paths along the riverbanks, where you can connect with the serene beauty of Argentina's countryside. **Adventure** In Mesopotamia, explore the lush landscapes of the Iberá Wetlands, where you can kayak through pristine waters and spot diverse wildlife. Discover the enchanting trails of the Quebrada de Humahuaca, perfect for hiking and immersing yourself in breathtaking scenery and cultural heritage. **Nightlife** Experience the vibrant nightlife at La Casa de la Cerveza for a variety of local brews and lively atmosphere. For a unique twist, visit El Rincón de la Música, where you can enjoy live tango performances while sipping on traditional Argentine cocktails. ### Booking tips and Expedia advantages for Mesopotamia To save money during your visit to Mesopotamia, plan your trip during the off-peak months, avoiding July, August, and December when prices rise. Book your hotel about a month in advance or take advantage of last-minute deals on Expedia, especially on Tuesdays for the best rates. Utilise Expedia’s search tools to find eco-friendly accommodations and combine bookings for flights and activities to secure better deals. Additionally, explore free activities and consider walking to save on public transport costs while enjoying the local scenery. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Mesopotamia are , where the prices are slightly lower. This is in comparison to July to August and December, where prices are slightly higher. - **The best time to book a hotel:** The cheapest time to book a hotel around Mesopotamia is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday. - **Find cheap hotels on Expedia:** Make use of Expedia’s search tool to refine your choices based on your budget, preferred location, and the type of hotel you desire. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels currently available. To find the most affordable prices and offers, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You may find that you can reduce your expenses by combining your hotel reservation in Mesopotamia with your flights and activities through an Expedia package. ### Find the best attractions near Mesopotamia Mesopotamia, Argentina, offers a delightful blend of family-friendly entertainment and adventurous activities, making it an ideal destination for a holiday. The area boasts stunning national parks and scenic landscapes, perfect for those seeking outdoor experiences. Whether you're looking for thrilling adventures or simply want to immerse yourself in nature, Mesopotamia has something to cater to every traveller's taste. - **Portal Carambola:** Nestled 8.7km from Mesopotamia, this national park offers thrilling outdoor adventures and breathtaking scenery, perfect for nature enthusiasts seeking an exhilarating escape into Argentina's stunning landscapes. ### Best time to go to Mesopotamia The best time to visit Mesopotamia can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Mesopotamia falls in January and February. February has visitor numbers and mostly sunny weather. The coolest average temperature around Mesopotamia falls in April and July. July has visitor numbers and mostly sunny weather. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 80.1°F (26.700000000000003°C) | Light Rain | Sunny | Average | Slightly High | | February | 77.7°F (25.4°C) | Light Rain | Mostly Sunny | | | | March | 72.9°F (22.700000000000003°C) | Light Rain | Mostly Sunny | Moderately High | Slightly High | | April | 66.7°F (19.3°C) | Light Rain | Mostly Sunny | Moderately High | Average | | May | 59.5°F (15.3°C) | Light Rain | Mostly Sunny | | | | June | 60.1°F (15.6°C) | Light Rain | Mostly Sunny | | | | July | 53.4°F (11.9°C) | Light Rain | Mostly Sunny | | | | August | 63.7°F (17.6°C) | Light Rain | Mostly Sunny | | | | September | 60.6°F (15.9°C) | Light Rain | Mostly Sunny | | | | October | 65.8°F (18.8°C) | Light Rain | Mostly Sunny | | | | November | 72.3°F (22.4°C) | Light Rain | Sunny | Moderately High | Average | | December | 77.0°F (25.0°C) | Light Rain | Sunny | Moderately High | Slightly High | ### The nearest major airports for your trip to Mesopotamia Accessing Mesopotamia, Argentina, can be achieved through several nearby airports. Posadas (PSS-Libertador General Jose de San Martin) lies 85.8km away, with hotel options like [Hotel Batista](https://www.expedia.co.uk/Posadas-Hotels-HOTEL-BATISTA.h74268703.Hotel-Information), 1.9km away, and [Continental Posadas Hotel](https://www.expedia.co.uk/Posadas-Hotels-Continental-Posadas-Hotel.h24990493.Hotel-Information), 3.1km away. Resistencia (RES-Resistencia Intl.) is 111.9km from Mesopotamia, offering hotels such as [Amérian Hotel Casino Gala](https://www.expedia.co.uk/Resistencia-Hotels-Amerian-Hotel-Casino-Gala.h1197026.Hotel-Information), 2.5km away, and [Gala Hotel y Convenciones](https://www.expedia.co.uk/Resistencia-Hotels-Gala-Hotel-Y-Convenciones.h12370608.Hotel-Information), 1.2km away. Lastly, Corrientes (CNQ-Corrientes Intl.) is 101.2km distant, featuring [La Rozada Suites](https://www.expedia.co.uk/Corrientes-Hotels-La-Rozada-Suites.h5172366.Hotel-Information), 3.1km away, with airport transportation available for a fee. Each airport provides convenient access to Mesopotamia for a delightful stay. ## Explore a world of travel with Expedia - More ways to book - [Book Hotels in Mesopotamia on Expedia.com.ar ](https://www.expedia.com.ar/Mesopotamia-Hoteles.d6208836.Guia-de-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app