Title: TOP Luxury Hotels in Historic Route 66 for 2025 - Historic Route 66 Upscale Hotels | Expedia.co.uk [Historic Route 66 Travel Guide](https://expedia.co.uk/Historic-Route-66.dx702654640613646336)[Hotels in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels)[Holiday Rentals in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Holiday-Rentals.d702654640613646336.Travel-Guide-HolidayRentals)[Flights to Historic Route 66](https://expedia.co.uk/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights)[Historic Route 66 Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Historic-Route-66.d702654640613646336.Car-Hire-Guide)[Historic Route 66 Holidays](https://expedia.co.uk/Historic-Route-66.d702654640613646336.Holidays-City-Breaks) ![Tulsa which includes a high-rise building, a bridge and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/258000/258650-Tulsa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Historic Route 66 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Historic Route 66 Luxury Hotels Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-10-10&endDate=2025-10-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-10-11&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Historic Route 66 Luxury Hotels ## Find out more about Historic Route 66 ### Historic Route 66and its attractions for luxury travelers Travel along Historic Route 66 and discover a tapestry of luxury and adventure, perfectly tailored for discerning travellers. Start your journey in Santa Monica, where the iconic pier offers a striking sunset view; indulge in upscale dining at The Lobster, renowned for its fresh seafood and ocean vistas. Next, visit the charming town of Williams, Arizona, known as the "Gateway to the Grand Canyon." Here, you can stay at the Grand Canyon Railway Hotel, which provides a unique train experience to the canyon, marrying nostalgia with modern comfort. Don’t miss the chance to explore the stunning landscapes of the Painted Desert, where guided luxury tours can reveal hidden gems and offer gourmet picnics against a backdrop of vibrant colours. In Albuquerque, enjoy the annual International Balloon Fiesta, where you can sip on fine wines while watching the sky fill with colourful hot air balloons—an experience that’s truly breathtaking. Finally, unwind in the upscale surroundings of a boutique hotel in Tulsa, Oklahoma, where art deco architecture meets contemporary luxury, ensuring you feel pampered at every turn. The Historic Route 66 offers a distinctive blend of culture, adventure, and relaxation that’s sure to impress even the most seasoned luxury traveller. ## Top Historic Route 66 Hotel Reviews ![Congress Plaza Hotel](//images.trvl-media.com/lodging/1000000/10000/6500/6452/a9ee91b7_y.jpg) ### Congress Plaza Hotel 10/10 Excellent "Great stay" [](https://expedia.co.uk/Chicago-Hotels-Congress-Plaza-Hotel.h6452.Hotel-Information) ![InterContinental Chicago Magnificent Mile by IHG](//images.trvl-media.com/lodging/1000000/30000/20300/20205/35cb1bb8_y.jpg) ### InterContinental Chicago Magnificent Mile by IHG 10/10 Excellent "-" [](https://expedia.co.uk/Chicago-Hotels-InterContinental-Chicago-Magnificent-Mile.h20205.Hotel-Information) ![Hilton Garden Inn Chicago Downtown/Magnificent Mile](//images.trvl-media.com/lodging/1000000/430000/424200/424187/d51caee8_y.jpg) ### Hilton Garden Inn Chicago Downtown/Magnificent Mile 10/10 Excellent "good location. short walk away to many attractions" [](https://expedia.co.uk/Chicago-Hotels-Hilton-Garden-Inn-Chicago-DowntownMagnificent-Mile.h424187.Hotel-Information) ![Club Quarters Hotel, Central Loop, Chicago](//images.trvl-media.com/lodging/1000000/570000/565800/565746/19b0236f_y.jpg) ### Club Quarters Hotel, Central Loop, Chicago 10/10 Excellent "Perfecto .Se encuentra en el centro." [](https://expedia.co.uk/Chicago-Hotels-Club-Quarters-Hotel.h565746.Hotel-Information) ![The Wade](//images.trvl-media.com/lodging/1000000/10000/1400/1346/f26e0a61_y.jpg) ### The Wade 10/10 Excellent "Right across the street from the navy pier! Everything about the hotel is amazing as far as the lobby, weight room, pool, and room. The only thing that wasn’t good was the beds themselves. The weren’t comfortable. Other than that great place to stay." [](https://expedia.co.uk/Chicago-Hotels-W-Chicago-Lakeshore.h1346.Hotel-Information) ![The Allegro Royal Sonesta Hotel Chicago Loop](//images.trvl-media.com/lodging/1000000/40000/34500/34496/69c2e798_y.jpg) ### The Allegro Royal Sonesta Hotel Chicago Loop 10/10 Excellent "Very friendly staff. Great at deco decor. " [](https://expedia.co.uk/Chicago-Hotels-The-Allegro-Royal-Sonesta-Hotel.h34496.Hotel-Information) ![Hilton Chicago/Magnificent Mile Suites](//images.trvl-media.com/lodging/1000000/20000/18600/18514/f21f6764_y.jpg) ### Hilton Chicago/Magnificent Mile Suites 10/10 Excellent "Awesome hotel. Super nice staff!" [](https://expedia.co.uk/Chicago-Hotels-Hilton-ChicagoMagnificent-Mile-Suites.h18514.Hotel-Information) ![Freehand Chicago](//images.trvl-media.com/lodging/10000000/9420000/9418300/9418281/3b3ade3c_y.jpg) ### Freehand Chicago 10/10 Excellent "Excellent location, clean and good room partners " [](https://expedia.co.uk/Chicago-Hotels-Freehand-Chicago.h9418281.Hotel-Information) ![The Whitehall Hotel, BW Premier Collection](//images.trvl-media.com/lodging/1000000/20000/18000/17903/daaf5f2e_y.jpg) ### The Whitehall Hotel, BW Premier Collection 10/10 Excellent "The location was great with the magnificent mile a minute walk away, the beach is also only a 5 minute walk. Breakfast was really good with all the usual options and the room was clean and cozy I would stay again! " [](https://expedia.co.uk/Chicago-Hotels-The-Whitehall-Hotel.h17903.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels near Lake Michigan](https://www.expedia.co.uk/Lake-Michigan-Hotels.0-l6338716-0.Travel-Guide-Filter-Hotels) - [Cottages in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Cottages.d6233674-aaCottages.Travel-Guide-Accommodation) - [Casino Hotels in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Casino-Hotel.0-0-d6233674-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Gay-Friendly-Hotel.0-0-d6233674-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Historic-Hotel.0-0-d6233674-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Hotel-With-A-Bar.0-0-d6233674-thotelwithabar.Travel-Guide-Filter-Hotels) - 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