Title: TOP Luxury Hotels in Historic Route 66 for 2026 - Historic Route 66 Upscale Hotels | Expedia.co.uk [Historic Route 66 Travel Guide](https://expedia.co.uk/Historic-Route-66.dx702654640613646336)[Hotels in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels)[Holiday Rentals in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Holiday-Rentals.d702654640613646336.Travel-Guide-HolidayRentals)[Flights to Historic Route 66](https://expedia.co.uk/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights)[Historic Route 66 Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Historic-Route-66.d702654640613646336.Car-Hire-Guide)[Historic Route 66 Holidays](https://expedia.co.uk/Historic-Route-66.d702654640613646336.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/1218/93b64b3e-64f1-4166-b6ae-c4c686f3ea8b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1218/93b64b3e-64f1-4166-b6ae-c4c686f3ea8b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Historic Route 66 Luxury Hotels Tonight [29 Mar - 30 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2026-03-29&endDate=2026-03-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [30 Mar - 31 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2026-03-30&endDate=2026-03-31&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2026-04-03&endDate=2026-04-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2026-04-10&endDate=2026-04-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Historic Route 66 luxury hotels ![Serves breakfast, lunch and dinner](https://images.trvl-media.com/lodging/4000000/3540000/3538400/3538327/83e4c147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch and dinner](https://images.trvl-media.com/lodging/4000000/3540000/3538400/3538327/e824a8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3540000/3538400/3538327/459a3527.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/4000000/3540000/3538400/3538327/1f085992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Chicago [](https://www.expedia.co.uk/Chicago-Hotels-JW-Marriott-Chicago.h3538327.Hotel-Information) Downtown Chicago 9.2/10 Wonderful (1,000 reviews) "Hot tubs was the best part!! Super hot water " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Myeisha £203 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Chicago-Hotels-JW-Marriott-Chicago.h3538327.Hotel-Information) ![Nightclub](https://images.trvl-media.com/lodging/3000000/2160000/2151900/2151878/6f853099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2160000/2151900/2151878/d0c2944a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2160000/2151900/2151878/1893647b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/3000000/2160000/2151900/2151878/0a805224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Loop Hotel [](https://www.expedia.co.uk/Chicago-Hotels-Central-Loop-Hotel.h2151878.Hotel-Information) Downtown Chicago 8.6/10 Excellent (2,046 reviews) "Staff was friendly and location was central to walk to many of the big sights " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jensen £97 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Chicago-Hotels-Central-Loop-Hotel.h2151878.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/58000000/57660000/57651200/57651125/6c1738b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Latin American cuisine ](https://images.trvl-media.com/lodging/58000000/57660000/57651200/57651125/cadeb422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake view](https://images.trvl-media.com/lodging/58000000/57660000/57651200/57651125/5d460cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/58000000/57660000/57651200/57651125/a68260d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sable at Navy Pier Chicago, Curio Collection by Hilton [](https://www.expedia.co.uk/Chicago-Hotels-Sable-At-Navy-Pier-Chicago.h57651125.Hotel-Information) Downtown Chicago 9.4/10 Exceptional (2,425 reviews) "Great spot and view, would stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly £169 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Chicago-Hotels-Sable-At-Navy-Pier-Chicago.h57651125.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/8100/8079/9d783fbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8079/1c7b677d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/8100/8079/8318473d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/8100/8079/832f7b8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palmer House a Hilton Hotel [](https://www.expedia.co.uk/Chicago-Hotels-Palmer-House-A-Hilton-Hotel.h8079.Hotel-Information) Downtown Chicago 8.6/10 Excellent (2,342 reviews) "Beautiful property, great resturant on site, an the pool and spa was amazing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim £138 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Chicago-Hotels-Palmer-House-A-Hilton-Hotel.h8079.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/7000000/6080000/6076700/6076623/2b83cf64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, sports bar](https://images.trvl-media.com/lodging/7000000/6080000/6076700/6076623/654947e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Arcade](https://images.trvl-media.com/lodging/7000000/6080000/6076700/6076623/7cff75a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/7000000/6080000/6076700/6076623/acab5e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Twin Arrows Navajo Casino Resort [](https://www.expedia.co.uk/Grand-Canyon-Hotels-Twin-Arrows-Navajo-Casino-Resort.h6076623.Hotel-Information) Flagstaff 9.6/10 Exceptional (2,057 reviews) "Great staff, comfortable rooms and bed, clean and easy drive to ski areas and flagstaff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan £80 includes taxes & fees 1 Apr - 2 Apr [](https://www.expedia.co.uk/Grand-Canyon-Hotels-Twin-Arrows-Navajo-Casino-Resort.h6076623.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Mediterranean cuisine ](https://images.trvl-media.com/lodging/35000000/34770000/34761400/34761378/8d2143ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34770000/34761400/34761378/w1101h1283x0y1-ef09926c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/35000000/34770000/34761400/34761378/52469d4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34770000/34761400/34761378/9752c1a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hoxton Chicago [](https://www.expedia.co.uk/Chicago-Hotels-The-Hoxton-Chicago.h34761378.Hotel-Information) Downtown Chicago 9.0/10 Wonderful (1,003 reviews) "Super cute hotel. Great bar and food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia £157 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Chicago-Hotels-The-Hoxton-Chicago.h34761378.Hotel-Information) ![Executive lounge](https://images.trvl-media.com/lodging/1000000/20000/16000/15937/8bd99f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16000/15937/84fcc5bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/20000/16000/15937/7915e59f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fairmont Gold, Suite, 1 King Bed, Accessible | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/20000/16000/15937/3b05bc98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairmont Chicago at Millennium Park [](https://www.expedia.co.uk/Chicago-Hotels-Fairmont-Chicago-At-Millennium-Park.h15937.Hotel-Information) Downtown Chicago 8.8/10 Excellent (2,095 reviews) "lovely hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alyvia £203 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Chicago-Hotels-Fairmont-Chicago-At-Millennium-Park.h15937.Hotel-Information) ![Room service – dining](https://images.trvl-media.com/lodging/1000000/10000/1400/1346/109a2156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1346/6d9bcb03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1346/eea57c7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1400/1346/da99f4b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wade [](https://www.expedia.co.uk/Chicago-Hotels-W-Chicago-Lakeshore.h1346.Hotel-Information) Downtown Chicago 8.4/10 Very good (1,761 reviews) "Staff was friendly, explained the hotel and amenities well. Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £150 includes taxes & fees 27 Apr - 28 Apr [](https://www.expedia.co.uk/Chicago-Hotels-W-Chicago-Lakeshore.h1346.Hotel-Information) ![2 bars/lounges](https://images.trvl-media.com/lodging/1000000/20000/19300/19215/1e5dfdc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/19300/19215/a00357b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/19300/19215/82978823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/19300/19215/cff11fef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Chicago Downtown Hotel [](https://www.expedia.co.uk/Chicago-Hotels-Renaissance-Chicago-Downtown-Hotel.h19215.Hotel-Information) Downtown Chicago 9.2/10 Wonderful (1,001 reviews) "Clean Room, Friendly and attentive staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix £170 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Chicago-Hotels-Renaissance-Chicago-Downtown-Hotel.h19215.Hotel-Information) ![Reception hall](https://images.trvl-media.com/lodging/2000000/1890000/1880400/1880320/8076f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Magnificent) | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/2000000/1890000/1880400/1880320/53a89031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1890000/1880400/1880320/a08df61e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/2000000/1890000/1880400/1880320/afa1818a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eurostars Magnificent Mile [](https://www.expedia.co.uk/Chicago-Hotels-Eurostars-Magnificent-Mile.h1880320.Hotel-Information) Downtown Chicago 9.0/10 Wonderful (3,346 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariah £106 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Chicago-Hotels-Eurostars-Magnificent-Mile.h1880320.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14®ionId=702654640613646336&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Find out more about Historic Route 66 ### Historic Route 66and its attractions for luxury travelers Travel along Historic Route 66 and discover a tapestry of luxury and adventure, perfectly tailored for discerning travellers. Start your journey in Santa Monica, where the iconic pier offers a striking sunset view; indulge in upscale dining at The Lobster, renowned for its fresh seafood and ocean vistas. Next, visit the charming town of Williams, Arizona, known as the "Gateway to the Grand Canyon." Here, you can stay at the Grand Canyon Railway Hotel, which provides a unique train experience to the canyon, marrying nostalgia with modern comfort. Don’t miss the chance to explore the stunning landscapes of the Painted Desert, where guided luxury tours can reveal hidden gems and offer gourmet picnics against a backdrop of vibrant colours. In Albuquerque, enjoy the annual International Balloon Fiesta, where you can sip on fine wines while watching the sky fill with colourful hot air balloons—an experience that’s truly breathtaking. Finally, unwind in the upscale surroundings of a boutique hotel in Tulsa, Oklahoma, where art deco architecture meets contemporary luxury, ensuring you feel pampered at every turn. The Historic Route 66 offers a distinctive blend of culture, adventure, and relaxation that’s sure to impress even the most seasoned luxury traveller. ## Top Historic Route 66 Hotel Reviews ![The Aquarius Casino Resort, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/10000/5100/5073/00385ed3_y.jpg) ### The Aquarius Casino Resort, BW Premier Collection 10/10 Excellent "Comfortable and clean. The pool was nice and warm. The servers were quick and professional. " [](https://expedia.co.uk/Laughlin-Hotels-The-Aquarius-Casino-Resort.h5073.Hotel-Information) ![Little America Flagstaff](https://images.trvl-media.com/lodging/1000000/20000/19800/19758/019ac46f_y.jpg) ### Little America Flagstaff 10/10 Excellent "Hidden gem. Do not judge the outside. That would be a mistake. It was wonderful. Clean, classy, just all around great. " [](https://expedia.co.uk/Grand-Canyon-Hotels-Little-America-Flagstaff.h19758.Hotel-Information) ![Hyatt Regency Chicago](https://images.trvl-media.com/lodging/1000000/10000/5000/4903/w3840h2559x0y3-c577bf94_y.jpg) ### Hyatt Regency Chicago 10/10 Excellent "Everything was great I will definitely be staying there again" [](https://expedia.co.uk/Chicago-Hotels-Hyatt-Regency-Chicago.h4903.Hotel-Information) ![Central Loop Hotel](https://images.trvl-media.com/lodging/3000000/2160000/2151900/2151878/6f853099_y.jpg) ### Central Loop Hotel 10/10 Excellent "We chose this location near the railway station, theaters, restaurants and museums. Clean, comfortable, appreciated the kitchenette, everything worked well. Minimal amenities but we didn't need them." [](https://expedia.co.uk/Chicago-Hotels-Central-Loop-Hotel.h2151878.Hotel-Information) ![Embassy Suites by Hilton Chicago Downtown River North](https://images.trvl-media.com/lodging/1000000/20000/11600/11580/24d28405_y.jpg) ### Embassy Suites by Hilton Chicago Downtown River North 4/10 Poor "Pretty pricey for what you actually get. Valet is $79 per night on top of room fee. Beds are hard and uncomfortable. The linen on bed was full of stains. The temperature in room is either too hot or too cold. Pool water is disgusting. On the other hand:valet staff was excellent. The location is excellent. Breakfast was okay as well. " [](https://expedia.co.uk/Chicago-Hotels-Embassy-Suites-Chicago-Downtown.h11580.Hotel-Information) ![Hilton Chicago](https://images.trvl-media.com/lodging/1000000/20000/12600/12570/274f52b9_y.jpg) ### Hilton Chicago 10/10 Excellent "Great stay! Room was amazing. Staff was fabulous! " [](https://expedia.co.uk/Chicago-Hotels-Hilton-Chicago.h12570.Hotel-Information) ![Hilton Chicago/Magnificent Mile Suites](https://images.trvl-media.com/lodging/1000000/20000/18600/18514/a215cd17_y.jpg) ### Hilton Chicago/Magnificent Mile Suites 10/10 Excellent "." [](https://expedia.co.uk/Chicago-Hotels-Hilton-ChicagoMagnificent-Mile-Suites.h18514.Hotel-Information) ![Don Laughlin's Riverside Resort Hotel & Casino](https://images.trvl-media.com/lodging/1000000/990000/988500/988479/69ffaad2_y.jpg) ### Don Laughlin's Riverside Resort Hotel & Casino 10/10 Excellent "Just a over all great place to stay in the desert " [](https://expedia.co.uk/Laughlin-Hotels-Don-Laughlins-Riverside-Resort-Hotel-Casino.h988479.Hotel-Information) ![The Wade](https://images.trvl-media.com/lodging/1000000/10000/1400/1346/109a2156_y.jpg) ### The Wade 10/10 Excellent "All staff members are really nice. Accomodated us well, no complaints." 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