A mural on a building with a man holding a machine and a sign that says "THIS LAND IS YOUR LAND".

Find luxury hotels in Historic Route 66

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Historic Route 66 Luxury Hotels

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Historic Route 66 luxury hotels

1. L7 Chicago by LOTTE

L7 Chicago by LOTTE
Downtown Chicago
£149
includes taxes & fees
9 Nov - 10 Nov
L7 Chicago by LOTTE

2. The Godfrey Hotel Chicago

The Godfrey Hotel Chicago
Downtown Chicago
  • City centre Chicago luxury with rooftop terrace, spa treatments, and stylish dining for discerning travellers.
£138
includes taxes & fees
1 Nov - 2 Nov
The Godfrey Hotel Chicago

3. The Wade

The Wade
Downtown Chicago
  • Luxurious lakeside retreat in city centre Chicago offers pillowtop beds, designer toiletries, and stunning views near Michigan Avenue.
£128
includes taxes & fees
1 Nov - 2 Nov
The Wade

4. Hard Rock Hotel and Casino Tulsa

Hard Rock Hotel and Casino Tulsa
Catoosa
  • Resort offers opulence with 8 restaurants, 2 pools, and a nightclub where luxury meets vibrant entertainment.
£107
includes taxes & fees
13 Oct - 14 Oct
Hard Rock Hotel and Casino Tulsa

5. Hotel 505 River North

Hotel 505 River North
Downtown Chicago
  • Luxury boutique indulgence meets Chicago vibrancy at this River North hotel with indoor pool and restaurant.
£194
includes taxes & fees
8 Nov - 9 Nov
Hotel 505 River North

6. Swissotel - Chicago

Swissotel - Chicago
Downtown Chicago
£217
includes taxes & fees
31 Oct - 1 Nov
Swissotel - Chicago

7. Hyatt Regency Tamaya Resort & Spa

Hyatt Regency Tamaya Resort & Spa
Santa Ana Pueblo
  • Riverside retreat offers pillowtop beds, spa services, 3 dining options, and poolside luxury amid mountains.
£229
includes taxes & fees
8 Nov - 9 Nov
Hyatt Regency Tamaya Resort & Spa

8. LondonHouse Chicago, Curio Collection by Hilton

LondonHouse Chicago, Curio Collection by Hilton
Downtown Chicago
  • Unwind in city centre Chicago's LondonHouse with rejuvenating spa treatments and riverfront luxury.
£235
includes taxes & fees
25 Oct - 26 Oct
LondonHouse Chicago, Curio Collection by Hilton

9. InterContinental Chicago Magnificent Mile by IHG

InterContinental Chicago Magnificent Mile by IHG
Downtown Chicago
  • Elegant city centre sanctuary boasts historic charm, luxury spa treatments, and a stunning indoor pool.
£217
includes taxes & fees
31 Oct - 1 Nov
InterContinental Chicago Magnificent Mile by IHG

10. The Westin Michigan Avenue Chicago

The Westin Michigan Avenue Chicago
Downtown Chicago
  • Indulgent spa retreats and upscale comforts define this luxury Michigan Avenue hotel.
£176
includes taxes & fees
8 Nov - 9 Nov
The Westin Michigan Avenue Chicago
View all properties

Find out more about Historic Route 66

Historic Route 66and its attractions for luxury travelers

Travel along Historic Route 66 and discover a tapestry of luxury and adventure, perfectly tailored for discerning travellers. Start your journey in Santa Monica, where the iconic pier offers a striking sunset view; indulge in upscale dining at The Lobster, renowned for its fresh seafood and ocean vistas. Next, visit the charming town of Williams, Arizona, known as the "Gateway to the Grand Canyon." Here, you can stay at the Grand Canyon Railway Hotel, which provides a unique train experience to the canyon, marrying nostalgia with modern comfort. Don’t miss the chance to explore the stunning landscapes of the Painted Desert, where guided luxury tours can reveal hidden gems and offer gourmet picnics against a backdrop of vibrant colours. In Albuquerque, enjoy the annual International Balloon Fiesta, where you can sip on fine wines while watching the sky fill with colourful hot air balloons—an experience that’s truly breathtaking. Finally, unwind in the upscale surroundings of a boutique hotel in Tulsa, Oklahoma, where art deco architecture meets contemporary luxury, ensuring you feel pampered at every turn. The Historic Route 66 offers a distinctive blend of culture, adventure, and relaxation that’s sure to impress even the most seasoned luxury traveller.

Top Historic Route 66 Hotel Reviews

The L Motel - Downtown Flagstaff

The L Motel - Downtown Flagstaff

8/10 Good
"O"
Yael 5-night trip
Posted 2 days ago
The L Motel - Downtown Flagstaff
Americas Best Value Inn & Suites Flagstaff

Americas Best Value Inn & Suites Flagstaff

8/10 Good
"Need a better breakfast--non sugary items and less carbs"
Roger 2-night trip
Posted 3 weeks ago
Americas Best Value Inn & Suites Flagstaff

Explore a world of travel with Expedia