Title: Historic Route 66 Travel Guide: Best of Historic Route 66, United States of America Travel 2026 | Expedia.co.uk [Hotels in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels)[Holiday Rentals in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Holiday-Rentals.d702654640613646336.Travel-Guide-HolidayRentals)[Flights to Historic Route 66](https://expedia.co.uk/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights)[Historic Route 66 Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Historic-Route-66.d702654640613646336.Car-Hire-Guide)[Historic Route 66 Holidays](https://expedia.co.uk/Historic-Route-66.d702654640613646336.Holidays-City-Breaks) # Historic Route 66 Travel Guide ## Tourist Guide ![Historic Route 66](https://mediaim.expedia.com/destination/9/17f13edc580f92fbd02b78ad30e73751.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Tulsa which includes a high-rise building, a bridge and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/258000/258650-Tulsa.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Albuquerque which includes mountains](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/169000/169647-Albuquerque.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Albuquerque showing signage](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/169000/169671-Albuquerque.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Woody Guthrie Center which includes outdoor art](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/258000/258658-Tulsa.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Historic Route 66 - Top hotels in Historic Route 66 - Top Holiday Rentals in Historic Route 66 ![Central Loop Hotel](https://images.trvl-media.com/lodging/3000000/2160000/2151900/2151878/43ee742c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Central Loop Hotel 111 West Adams Street Chicago IL £58 28 Jan - 29 Jan includes taxes & fees Stay at this boutique hotel in Chicago. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff in their ... 8.4/10 Very Good! (1,976 reviews) Clean and cozy room, friendly staff. I'll definitely be bsck. Reviewed on 5 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=28%2F01%2F2026&endDate=29%2F01%2F2026&selected=2151878&PinnedHotelID=2151878&HadPinnedHotel=true®ionId=702654640613646336) ![Hilton Chicago](https://images.trvl-media.com/lodging/1000000/20000/12600/12570/274f52b9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Chicago 720 S Michigan Ave Chicago IL £143 18 Jan - 19 Jan includes taxes & fees Stay at this 4-star historic hotel in Chicago. Enjoy 2 restaurants, breakfast (surcharge) and a health club. Our guests praise the helpful staff and the clean ... 8.4/10 Very Good! (2,502 reviews) Yes Reviewed on 7 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=18%2F01%2F2026&endDate=19%2F01%2F2026&selected=12570&PinnedHotelID=12570&HadPinnedHotel=true®ionId=702654640613646336) ![Palmer House a Hilton Hotel](https://images.trvl-media.com/lodging/1000000/10000/8100/8079/7f542141_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Palmer House a Hilton Hotel 17 E Monroe St Chicago IL £143 18 Jan - 19 Jan includes taxes & fees Stay at this luxury hotel in Chicago. Enjoy a full-service spa, breakfast (surcharge) and a 24-hour health club. Our guests praise the helpful staff and the ... 8.4/10 Very Good! (2,227 reviews) Room was very clean and staff was great Reviewed on 6 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=18%2F01%2F2026&endDate=19%2F01%2F2026&selected=8079&PinnedHotelID=8079&HadPinnedHotel=true®ionId=702654640613646336) [See all 19,658 properties in Historic Route 66](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=11%2F01%2F2026&endDate=12%2F01%2F2026®ionId=702654640613646336) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Sentral Michigan Avenue](https://images.trvl-media.com/lodging/77000000/76270000/76267500/76267438/a9b3121a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sentral Michigan Avenue 808 SOUTH MICHIGAN AVENUE Chicago IL Stay at this business-friendly aparthotel in Chicago. Enjoy a 24-hour fitness centre, valet parking (surcharge) and a 24-hour front desk. Our guests praise the ... 9.2/10 Wonderful! (1,034 reviews) This is a great place to stay with kids. Very clean and quiet! We loved having extra space and a full kitchen for breakfast. Our only drawback was that it really needs another hot tub and the pool was very cold, but the kids loved the attached game room! Overall, we had a great experience and will ... Reviewed on 3 Jan 2026 [](https://expedia.co.uk/Chicago-Hotels-Sentral-Michigan-Avenue.h76267438.Hotel-Information) ![Junipine Resort](https://images.trvl-media.com/lodging/1000000/530000/529700/529610/8fe942d6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Junipine Resort 8351 N Highway 89A Sedona AZ Stay at this aparthotel in Sedona. Enjoy free Wi-Fi, free parking and in-room massages. Our guests praise the helpful staff and the clean rooms in their reviews. ... 9.2/10 Wonderful! (2,257 reviews) Beautiful and clean and big. Reviewed on 5 Jan 2026 [](https://expedia.co.uk/Sedona-Hotels-Junipine-Resort.h529610.Hotel-Information) ![Level Chicago – Old Town](https://images.trvl-media.com/lodging/40000000/39810000/39805900/39805843/8a983359_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Level Chicago – Old Town 1140 North Wells Street Chicago IL Stay at this family-friendly aparthotel in Chicago. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the helpful staff in their reviews. ... 9/10 Wonderful! (408 reviews) My stay was great. The room was nice and the staff was very courteous throughout my stay. I will definitely stay again. Reviewed on 30 Dec 2025 [](https://expedia.co.uk/Chicago-Hotels-LEVEL-Furnished-Living-Chicago.h39805843.Hotel-Information) [See all properties in Historic Route 66](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=702654640613646336&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Historic Route 66 hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=702654640613646336&startDate=2026-01-10&endDate=2026-01-11)[10 Jan - 11 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=702654640613646336&startDate=2026-01-10&endDate=2026-01-11) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=702654640613646336&startDate=2026-01-11&endDate=2026-01-12)[11 Jan - 12 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=702654640613646336&startDate=2026-01-11&endDate=2026-01-12) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=702654640613646336&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026)[16 Jan - 18 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=702654640613646336&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026) ## Cities near Historic Route 66 ![Albuquerque which includes street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/169000/169675-Albuquerque.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Albuquerque ![Chicago showing a city and a skyscraper as well as a family](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/332000/332049-Chicago.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Chicago ![Northern Arizona showing street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/169000/169008-Flagstaff.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Flagstaff ![Photo by Mindi Feldstein](https://mediaim.expedia.com/destination/2/68d10a6be31dbab1f7bd0e06e4c77cb1.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Gallup ## Explore a world of travel with Expedia - 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