Find Spa Hotels in Florida Keys

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Check prices for these dates

Tonight
5 Nov - 6 Nov
Tomorrow
6 Nov - 7 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Florida Keys hotels with a spa

A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.

1. Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,507 reviews)
  • cleanliness
    Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
The price is £206
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
A beachside spa with two massage tables under a canopy, overlooking the sea and a pier.

2. Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.4 out of 10, Very good, (1,007 reviews)
  • cleanliness
    Beach resort with spa offering aromatherapy, Ayurvedic treatments, and beachside massages for ultimate relaxation.
The price is £214
includes taxes & fees
22 Nov - 23 Nov
Casa Marina Key West, Curio Collection by Hilton
A modern interior with a round wooden table, two glass-top side tables, and a textured wall.

3. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
4.0 star property
Marathon
8.6 out of 10, Excellent, (1,134 reviews)
  • cleanliness
    Rejuvenate at this waterfront resort's luxurious Ocean Spa with specialised massages in serene rooms.
The price is £144
includes taxes & fees
15 Nov - 16 Nov
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A hotel room with a bed, a dresser, a mirror, and a nightstand.

4. Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,562 reviews)
  • cleanliness
    Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
The price is £213
includes taxes & fees
30 Nov - 1 Dec
Reefhouse Resort & Marina
A swimming pool surrounded by palm trees and lounge chairs.

5. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Rejuvenate your spirit at this waterfront sanctuary where serene spa treatments complement 3 sparkling pools.
The price is £221
includes taxes & fees
2 Dec - 3 Dec
Tranquility Bay Beachfront Hotel and Resort
A room with a bed, a ceiling fan, and a view of the ocean.

6. Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (3,644 reviews)
  • cleanliness
    Serene beachside spa oasis offers tropical relaxation with ocean views and couples treatments.
The price is £221
includes taxes & fees
15 Nov - 16 Nov
Southernmost Beach Resort and Guesthouses
Lobby

7. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
5.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,218 reviews)
  • cleanliness
    Indulge in oceanfront spa retreats with sunset views at this tropical Key West haven just steps from Duval Street.
The price is £245
includes taxes & fees
1 Dec - 2 Dec
Opal Key Resort & Marina, Key West
A reception area with a wooden reception desk, a tiled wall, and a hanging light fixture.

8. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Waterfront resort spa with exotic massage options and ocean views offers full-service relaxation by the Key West sunset.
The price is £272
includes taxes & fees
19 Nov - 20 Nov
Ocean Key Resort - A Noble House Resort
A massage therapy session in a room with a city view.

9. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (1,062 reviews)
  • cleanliness
    Luxurious beachfront spa retreat offers deep-tissue massages and serene outdoor treatments in Key West.
The price is £234
includes taxes & fees
30 Nov - 1 Dec
The Reach Key West, Curio Collection by Hilton
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.

10. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
The price is £261
includes taxes & fees
29 Nov - 30 Nov
Playa Largo Resort & Spa, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Florida Keys

Pool
Breakfast included

Top Florida Keys Hotel Reviews

A beach with palm trees, a thatched-roof structure, and kayaks.
Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor

10/10 Excellent

We originally booked Kona Kai for one night but we loved it so much we stayed for three nights. Kathryn and Zee, the office staff, were both a pure delight and very helpful. The room we had was like a small apartment and very well equipped. Nice private beach with kayaks, paddle boards and iguanas provided. There is a fairly decent restaurant across the road but it would be great if Kona Kai had a restaurant or bar too. We would definitely stay here again.
United Kingdom
Gino
Reviewed November 27, 2023
Kona Kai Resort and Gallery - Adults Only

Find out more about Florida Keys

Top Florida Keys attractions for a relaxing vacation

In the enchanting Florida Keys, travellers seeking spa hotel experiences will find a wealth of rejuvenating activities and serene spots to explore. Begin your day with a morning yoga session on the beach at the renowned Little Palm Island Resort, where the gentle sound of waves sets a tranquil tone for relaxation. Afterward, embark on a snorkelling adventure at John Pennekamp Coral Reef State Park, where you can marvel at vibrant marine life and colourful coral reefs. For a taste of local culture, visit the Ernest Hemingway Home and Museum in Key West, immersing yourself in the literary history of the area before retreating to your spa hotel for a soothing massage. As the sun sets, enjoy a sunset cruise through the crystal-clear waters of the Keys, an experience that can be beautifully complemented by a spa treatment tailored to ease your muscles after a day of adventure. The vibrant atmosphere of Key West, with its lively streets and charming architecture, offers a perfect backdrop for relaxation, making it an excellent area to stay. Here, luxurious spa hotels merge comfort with attentive service, ensuring families and high-end travellers alike feel pampered and valued throughout their stay.