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Compare car hire in Florida Keys,

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Nectar
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Nectar
Collect Nectar points
Nectar
Collect Nectar points
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Top Car Deals in Florida Keys

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Economy

Passengers 4 Luggage Capacity 2
Economy

Compact

Passengers 4 Luggage Capacity 2
Compact

Midsize

Passengers 5 Luggage Capacity 3
Midsize

SUV

Passengers 5 Luggage Capacity 4
SUV

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Explore Florida Keys

Explore Florida Keys with Expedia’s Travel Guides to find the best hotels, flights, holiday packages and more!

Expedia car hire in Florida Keys comes with No Hidden Fees

Hire a Car and Explore Florida Keys

The long chain of islands that make up Florida Keys stretches from Miami through the Gulf of Mexico almost all the way to Cuba. Yet it is not a boat you need to explore Florida Keys, but a car. The Overseas Highway runs 113 miles, linking the islands of the Florida Keys and creating one of the best drives in the US. Renting a car is by far the best way to get the most out of your time in Florida Keys.

All the big-name international brand car hire companies are represented in Florida Keys, plus several good local ones, too, and you can rent cars from several places. The international airports of Miami, Key West and Marathon offer perhaps the biggest choice.

The Overseas Highway: A Road over Ocean

The Overseas Highway is an architectural marvel and one of only 30 All-American Roads. It is the southernmost part of US Route 1 Highway and follows the path of the original railroad that once connected the islands.

Driving the Overseas Highway is one of the true highlights of a trip to Florida Keys. You will cross vast stretches of blue seas, and pass tangled mangroves, vibrant resorts and little harbours to stop off for lunch or a wander. While Seven Mile Bridge in Marathon is probably the most famous section of the Overseas Highway, almost every stretch opens up impressive sunsets and views and, if you hire a convertible car, a real wind-in-your-hair experience.