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Featured Florida Keys Spa Hotels

See all 1,047 Hotels in Florida Keys
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82, Islamorada
4.5 out of 5.0
4.4 out of 5 (1,433 reviews)
Daughter got married here on the beach at sunset. Beautiful hotel and spa facilities. Close enough to Miami in terms of travel, but you feel like you're away in the Caribbean.
  11 Sep 2017
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
4.5 out of 5.0
4.4 out of 5 (1,444 reviews)
Great birthday stayHotel is awesome! Convenient location to Duval St. but still quiet. Beach, tiki bar, and onsite bar were great. Ocean view room was perfect and staff did an excellent job. Would definitely stay there again...
  15 Jan 2018

£253

£253
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
4.0 out of 5.0
4.5 out of 5 (3,148 reviews)
Quiet end of Duval StThe stay was nice. $25.00 a day to park is a bit much when you pay a resort fee. The staff needs to agree on where the smoking is allowed, my wife was told one place and by the front desk employees, and some employees told her she couldn't smoke there. Employees using blowers on the property were ...
  22 Jan 2018

£189

£189
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

601 Front St, Key West
4.5 out of 5.0
4.4 out of 5 (1,303 reviews)
Friendly staff willing to go the extra mile and make you feel like you are important to them.
  19 Dec 2017

£302

£302
La Concha Hotel & Spa

La Concha Hotel & Spa

430 Duval St, Key West
4.5 out of 5.0
4.1 out of 5 (1,784 reviews)
Great location on DuvallStaff was friendly and accommodating. I chose to stay there, due to location and appearance of hotel, for the half marathon. Greatly enjoyed hot stone massage by an excellent masseuse after completing race. Location of hotel, made it very easy to get to popular locations throughout town without the ...
  22 Jan 2018

£171

£171
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Zero Duval St., Key West
4.5 out of 5.0
4.6 out of 5 (1,669 reviews)
cool weather. slept amazingWe had a balcony which overlooked Duval. It was nice to keep the door open at night and hear the ocean when the temperature dropped at night. Slept like a champ. Staff was very friendly. Room and grounds were clean. My only disappointment was that I could not take the nice shampoo/conditioner and ...
  17 Jan 2018

£228

£228
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd, Duck Key
4.5 out of 5.0
4.2 out of 5 (1,930 reviews)
Nice resort with its own beach and 2 pools We love staying at Hawk's Cay. I love that they have heir own little private beach/lagoon area. Main pool is beautiful, but when you want to get away from other people's kids, there is an adult pool as well. It's a little older but still really nice. My only complaint is that is that the menus have ...
  17 Sep 2017
Paradise Inn Key West-Adults Only

Paradise Inn Key West-Adults Only

819 Simonton Street, Key West
4.0 out of 5.0
4.6 out of 5 (863 reviews)
Nice and cute hotelNice hotel overall, super nice staff and the breakfast is good. Resort facilities including pool and spa. The parking is right in front of you, not like other valet parking, they park your car in to public parking and drive them back when you need it.
  12 Jan 2018

£196

£196
Artist House on Fleming

Artist House on Fleming

1016 Fleming St., Key West
4.0 out of 5.0
4.6 out of 5 (140 reviews)
Staff were very friendly and it was never a problem to help you with anything. The room was spacious and very clean. I will be going back next year. Great position to the main area of the island.
  27 Dec 2017

£144

£144
Seascape Inn

Seascape Inn

420 Olivia Street, Key West
3.5 out of 5.0
4.3 out of 5 (77 reviews)
Nice hotel, great location.We have stayed at the Seascape 4 times. The rooms are nice, they have a continental breakfast, and you can't beat the location. Just steps away from Duval Street.
  11 Aug 2017

£234

£234
Map

Recently booked Florida Keys hotels

Artist House on Fleming
4.0 out of 5.0
Last booking: 6 minutes ago
Southernmost Beach Resort
4.0 out of 5.0
Last booking: 11 minutes ago
The Marker Waterfront Resort Key West
4.5 out of 5.0
Last booking: 33 minutes ago
Creekside Inn Islamorada
3.0 out of 5.0
Last booking: 50 minutes ago
Banana Bay Resort & Marina
3.0 out of 5.0
Last booking: 51 minutes ago
Key Largo Bay Marriott Beach Resort
4.0 out of 5.0
Last booking: 54 minutes ago
Hyatt Centric Key West Resort and Spa
4.5 out of 5.0
Last booking: 1 hour ago
Orchid Key Inn
3.5 out of 5.0
Last booking: 1 hour ago
The Marquesa Hotel
3.5 out of 5.0
Last booking: 1 hour ago

Relaxing Spa Hotels in Florida Keys

The laid-back Florida Keys are famously on island time, so unwinding on these stunning sun-soaked islands comes naturally. But if there is one thing sure to help you get into the Florida Keys’ mindset, it’s checking in to the soothing surroundings of a spa hotel.

Spa hotels in the Florida Keys make the most of their environment, offering luxury treatments in calming surroundings. And the beautiful natural world around the spas comes into play on their treatment menus, with al fresco massages available in some. These can be taken on sea-view balconies in your own room, in secluded tropical hotel gardens or on the beach, with the sounds and smells of the ocean as the backdrop. Or, if you really want to be at one with nature, choose a spa hotel that offers massage treatments on tables out in the water.

Find Hotels with Spas in Florida Keys

Check into a spa hotel in Key Largo, at the top of the Key West island chain, and you will be right on top of the John Pennekamp State Park. This underwater wonderland is home to mile after nautical mile of colourful coral and tropical fish. Spa hotels in Islamorada, meanwhile, place you at the heart of the self-titled sport fishing capital of the world, where you can spend lazy afternoons fishing on the backcountry waters. All of the islands in Florida Keys are known for being calm and carefree, but the pace really shifts down a gear as you move south towards the Lower Keys and Key West.

Spa hotels in Key West range from small luxury hotels to sprawling waterfront resorts. Whirlpool hot tubs, steam rooms and state-of-the-art treatment facilities are some of features you can expect to find when you put on your bathrobe and head inside your serene and stylish health resorts. Spa menus offer rejuvenating facials and soothing massages, plus exotic treatments inspired by alternative therapies from around the world. There are even pampering packages tailor-made for sunbathers who have been laying out in the Florida sunshine, with special ingredients that nourish sun-kissed skin.