Title: TOP Luxury Hotels in Florida Keys for 2026 - Florida Keys Upscale Hotels | Expedia.co.uk

[Florida Keys Travel Guide](https://expedia.co.uk/Florida-Keys.dx6023765)[Hotels in Florida Keys](https://expedia.co.uk/Florida-Keys-Hotels.d6023765.Travel-Guide-Hotels)[Holiday Rentals in Florida Keys](https://expedia.co.uk/Florida-Keys-Holiday-Rentals.d6023765.Travel-Guide-HolidayRentals)[Flights to Florida Keys](https://expedia.co.uk/Cheap-Flights-To-Florida-Keys.d6023765.Travel-Guide-Flights)[Things to do in Florida Keys](https://expedia.co.uk/Things-To-Do-In-Florida-Keys.d6023765.Travel-Guide-Activities)[Florida Keys Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Florida-Keys.d6023765.Car-Hire-Guide)[Florida Keys Holidays](https://expedia.co.uk/Florida-Keys.d6023765.Holidays-City-Breaks)

![Higgs Beach showing tropical scenes and a beach as well as a large group of people](https://images.trvl-media.com/place/6246822/f00ad239-b8ad-4f0c-b162-acc6426db1e2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find luxury hotels in Florida Keys

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## Check availability on Florida Keys Luxury Hotels

Tonight

[9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-01-09&endDate=2026-01-10&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-01-10&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Florida Keys luxury hotels

![On the beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/dd7d4fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony view](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/55a08207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/a064415d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony view](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/95dbc957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Islands of Islamorada

[](https://www.expedia.co.uk/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information)

Matecumbe

9.8/10

Exceptional

(70)

"Amazing stay, can’t wait to stay there again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

£550

includes taxes & fees

13 Jan - 14 Jan

[](https://www.expedia.co.uk/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information)

![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/a299c4a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/048e43bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/fc1e65ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/05980c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ocean Key Resort - A Noble House Resort

[](https://www.expedia.co.uk/Key-West-Hotels-Ocean-Key-Resort-A-Noble-House-Resort.h16682.Hotel-Information)

Key West Historic District

9.2/10

Wonderful

(1004)

"Nice hotel but a lot of construction going on"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tobias

£418

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-Ocean-Key-Resort-A-Noble-House-Resort.h16682.Hotel-Information)

![Suite, 1 King Bed, Lanai, Oceanfront | View from room](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/14292c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/1b169515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/7df2a82d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/4caaa3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Marina Key West, Curio Collection by Hilton

[](https://www.expedia.co.uk/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information)

Old Town Key West

8.4/10

Very good

(500)

"Great place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ELENA

£455

includes taxes & fees

13 Jan - 14 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information)

![2 outdoor pools, pool loungers](https://images.trvl-media.com/lodging/1000000/920000/911000/910922/069776b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/911000/910922/14c574b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury 2 bedroom Bi-level Garden View Suite | Balcony view](https://images.trvl-media.com/lodging/1000000/920000/911000/910922/5fa9c353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/920000/911000/910922/b4d45af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Santa Maria Suites

[](https://www.expedia.co.uk/Key-West-Hotels-Santa-Maria-Suites.h910922.Hotel-Information)

Old Town Key West

9.6/10

Exceptional

(1004)

"Awesome place we loved it"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Josh

£476

includes taxes & fees

13 Jan - 14 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-Santa-Maria-Suites.h910922.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/8c74658c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, beach cabanas, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/d9cc2f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/ba58782b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves lunch and dinner](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/bb9d7ce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Playa Largo Resort & Spa, Autograph Collection

[](https://www.expedia.co.uk/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information)

Rock Harbor

8.8/10

Excellent

(1000)

"Courteous staff, clean, many extra like hot chocolate bar, s’mores station and coffee station. Nice stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kelley

£395

includes taxes & fees

22 Jan - 23 Jan

[](https://www.expedia.co.uk/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information)

![Front of property – evening/night](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/236726ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/d08fe38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mansion Room #201 - Ocean View with private balcony - Adults Only | Living area | 42-inch flat-screen TV with cable channels, TV, streaming services](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/b9fdadbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/00a251a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Southernmost House

[](https://www.expedia.co.uk/Key-West-Hotels-The-Southernmost-House-Hotel.h3830519.Hotel-Information)

Old Town Key West

9.4/10

Exceptional

(1000)

"Great place to stay. Staff was very friendly"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacob

£369

includes taxes & fees

14 Jan - 15 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-The-Southernmost-House-Hotel.h3830519.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1000/901/0b72a249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/1000/901/c028e7a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine, sea views ](https://images.trvl-media.com/lodging/1000000/10000/1000/901/cd7c9771.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room, 1 King Bed, Ocean View | Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1000/901/c6f4724b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Centric Key West Resort and Spa

[](https://www.expedia.co.uk/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information)

Key West Historic District

9.0/10

Wonderful

(1007)

"Staff was courteous and the location is perfect for a weekend in Key West."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

TIMOTHY

£412

includes taxes & fees

13 Jan - 14 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information)

![Private beach, white sand, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/c9267f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Oceanfront | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/f58d1ec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Dockside) | Living room | 42-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/053d9529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private beach, white sand, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/d58c67cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pier House Resort & Spa

[](https://www.expedia.co.uk/Key-West-Hotels-Pier-House-Resort-Spa.h19307.Hotel-Information)

Key West Historic District

9.0/10

Wonderful

(1020)

"4th time staying, great staff, location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffrey

£350

includes taxes & fees

12 Jan - 13 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-Pier-House-Resort-Spa.h19307.Hotel-Information)

![Private beach, scuba diving, sailing, kayaking](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/bc3021c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/48229e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/2fd2eeb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/dc04826f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Reach Key West, Curio Collection by Hilton

[](https://www.expedia.co.uk/Key-West-Hotels-The-Reach-Key-West.h457821.Hotel-Information)

Old Town Key West

8.6/10

Excellent

(1001)

"Great hotel, great beach, had a really good stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cristian Mihai

£384

includes taxes & fees

13 Jan - 14 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-The-Reach-Key-West.h457821.Hotel-Information)

![Food and drink](https://images.trvl-media.com/lodging/49000000/48720000/48713900/48713884/5fd7b8bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/49000000/48720000/48713900/48713884/82d7bf8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/49000000/48720000/48713900/48713884/62b1909b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/49000000/48720000/48713900/48713884/2ac07b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Margaritaville Beach House Key West

[](https://www.expedia.co.uk/Key-West-Hotels-Margaritaville-Beach-House-Key-West.h48713884.Hotel-Information)

Key West

8.8/10

Excellent

(1780)

"The location was pretty, with access to the beach, a restaurant, a bar, a pool and great service! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jayne

£366

includes taxes & fees

28 Jan - 29 Jan

[](https://www.expedia.co.uk/Key-West-Hotels-Margaritaville-Beach-House-Key-West.h48713884.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24&regionId=6023765&adults=2&sort=LUXURY&star=40,50&openPlayBack=true)

## Find out more about Florida Keys

### Florida Keysand its attractions for luxury travelers

The Florida Keys offer an exquisite playground for luxury travellers seeking both relaxation and adventure. Begin your journey in Key West, where you can explore the vibrant streets lined with historical architecture and indulge in exquisite dining at renowned establishments like Latitudes, known for its stunning sunset views and fresh seafood. Next, venture to the tranquil surroundings of Little Palm Island, a private resort accessible only by boat or seaplane, where you can unwind in a thatched-roof bungalow with unparalleled ocean views and a full-service spa. For those interested in marine life, a day trip to the Dry Tortugas National Park is a must; here, you can snorkel in crystal-clear waters, discovering vibrant coral reefs and diverse wildlife. The Keys also boast some of the finest fishing opportunities, with charter services available to take you out for a day on the water, targeting species like tarpon and bonefish. Finally, enjoy the laid-back elegance of Islamorada, where luxury resorts such as Cheeca Lodge offer lavish accommodations alongside activities like paddleboarding and sunset cruises. Staying in these luxurious settings ensures that every detail of your experience is catered to, allowing you to focus on making unforgettable memories.

## Top Florida Keys Hotel Reviews

![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg)

### Amara Cay Resort

10/10 Excellent

"Na"

[](https://expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information)

![Bayside Inn Key Largo](https://images.trvl-media.com/lodging/1000000/30000/22700/22657/419b7787_y.jpg)

### Bayside Inn Key Largo

10/10 Excellent

"Room was nice. Our coffee maker did not work but great coffee in the office area. Water pressure in room was very low. Awesome restaurant right next door. Overall nice place. Would stay here again. "

[](https://expedia.co.uk/Key-Largo-Hotels-Bayside-Inn-Key-Largo.h22657.Hotel-Information)

![Lime Tree Bay Resort](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/6f2246e8_y.jpg)

### Lime Tree Bay Resort

10/10 Excellent

"We greatly enjoyed our two nights at Lime Tree Bay. This low-key resort is a great place to relax and soak up the sun. Its private beach offers paddleboarding and kayaking by day and spectacular sunsets to top it off. The rooms are nice. Due to our own last-minute reservations, we had to switch rooms on the second day, but the new room, in the newer building, was even better than the first, and the staff was extremely accommodating in letting us stay in the first room until the second was ready. Overall, the staff is fantastic – friendly and helpful. We also took advantage of the free bikes for a ride to the nearby state park. Highly recommend. "

[](https://expedia.co.uk/Long-Key-Hotels-Lime-Tree-Bay-Resort.h882254.Hotel-Information)

![Waterside Suites & Marina](https://images.trvl-media.com/lodging/1000000/20000/13800/13719/7b7ca43b_y.jpg)

### Waterside Suites & Marina

10/10 Excellent

"Friendly staff, clean rooms, not far from highway, right on canal, just need to be able to handle stairs to get to upstairs bedroom/shower"

[](https://expedia.co.uk/Key-Largo-Hotels-Waterside-Suites-Marina.h13719.Hotel-Information)

![Marina Del Mar Resort and Marina](https://images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg)

### Marina Del Mar Resort and Marina

10/10 Excellent

"Amazing "

[](https://expedia.co.uk/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information)

![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg)

### Cheeca Lodge & Spa

10/10 Excellent

"The property is spectacular - absolutely beautiful, lit up at night with torches and lighting. The room was well appointed, clean and relaxing. The food was good, the service was excellent."

[](https://expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information)

![Holiday Inn Key Largo by IHG](https://images.trvl-media.com/lodging/1000000/10000/7300/7230/160ba216_y.jpg)

### Holiday Inn Key Largo by IHG

10/10 Excellent

"very good"

[](https://expedia.co.uk/Key-Largo-Hotels-Holiday-Inn-Key-Largo.h7230.Hotel-Information)

![Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/d10a018b_y.jpg)

### Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

10/10 Excellent

"Amazing place - so much variety"

[](https://expedia.co.uk/Islamorada-Hotels-Three-Waters-Resort-And-Marina.h11864.Hotel-Information)

![The Pelican Key Largo Cottages](https://images.trvl-media.com/lodging/7000000/6840000/6839400/6839376/f35b06df_y.jpg)

### The Pelican Key Largo Cottages

10/10 Excellent

"Very clean room, friendly staff!"

[](https://expedia.co.uk/Key-Largo-Hotels-The-Pelican-Key-Largo-Cottages.h6839376.Hotel-Information)

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