Find luxury hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Luxury Hotels

Our top choices for Florida Keys luxury hotels

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (73 reviews)
The price is £625
includes taxes & fees
13 Apr - 14 Apr
The Islands of Islamorada

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very good, (189 reviews)
  • cleanliness
    Indulge in oceanfront splendour at this Florida Keys resort with 5 pools, private beach, and full-service spa treatments.
The price is £617
includes taxes & fees
2 May - 3 May
Villas At Hawks Cay Resort

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,081 reviews)
The price is £262
includes taxes & fees
10 May - 11 May
Opal Key Resort & Marina, Key West

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,080 reviews)
The price is £451
includes taxes & fees
28 Apr - 29 Apr
Pier House Resort & Spa

Santa Maria Suites

Santa Maria Suites
4.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Lavish Key West retreat features luxury suites, designer touches, 2 pools, and vibrant bar scene.
The price is £417
includes taxes & fees
11 May - 12 May
Santa Maria Suites

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1,003 reviews)
The price is £384
includes taxes & fees
11 May - 12 May
Ocean Key Resort - A Noble House Resort

The Gardens Hotel

The Gardens Hotel
4.0 star property
Old Town Key West
9.8 out of 10, Exceptional, (1,002 reviews)
The price is £333
includes taxes & fees
6 May - 7 May
The Gardens Hotel

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.4 out of 10, Very good, (613 reviews)
  • cleanliness
    Beachfront luxury graces historic Key West resort with private shore access and spa treatments.
The price is £361
includes taxes & fees
12 May - 13 May
Casa Marina Key West, Curio Collection by Hilton

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,004 reviews)
  • cleanliness
    Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
The price is £341
includes taxes & fees
7 May - 8 May
Playa Largo Resort & Spa, Autograph Collection

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.8 out of 10, Excellent, (3,209 reviews)
  • cleanliness
    Coastal elegance meets beachfront luxury at this Key West retreat with 3 pools, spa, and oceanview dining.
The price is £331
includes taxes & fees
4 May - 5 May
Southernmost Beach Resort and Guesthouses
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Florida Keysand its attractions for luxury travelers

The Florida Keys offer an exquisite playground for luxury travellers seeking both relaxation and adventure. Begin your journey in Key West, where you can explore the vibrant streets lined with historical architecture and indulge in exquisite dining at renowned establishments like Latitudes, known for its stunning sunset views and fresh seafood. Next, venture to the tranquil surroundings of Little Palm Island, a private resort accessible only by boat or seaplane, where you can unwind in a thatched-roof bungalow with unparalleled ocean views and a full-service spa. For those interested in marine life, a day trip to the Dry Tortugas National Park is a must; here, you can snorkel in crystal-clear waters, discovering vibrant coral reefs and diverse wildlife. The Keys also boast some of the finest fishing opportunities, with charter services available to take you out for a day on the water, targeting species like tarpon and bonefish. Finally, enjoy the laid-back elegance of Islamorada, where luxury resorts such as Cheeca Lodge offer lavish accommodations alongside activities like paddleboarding and sunset cruises. Staying in these luxurious settings ensures that every detail of your experience is catered to, allowing you to focus on making unforgettable memories.

Top Florida Keys Hotel Reviews