
Esquilino Holidays from £298
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £335 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Esquilino Holiday
Discover the wonder of this commercial neighbourhood with an Esquilino holiday package. From its history and dining to its culture, there's something for every type of traveller. Not sure where to go during your trip to Esquilino? Nearby attractions such as St. Peters Basilica, Roman Forum and Pantheon are good places to begin. Expedia will help you turn your ideal Esquilino holiday into reality, no matter your budget or travel plans.

Grand Hotel Olympic
Reviewed on 11 Apr 2026



EXE Domus Aurea
Reviewed on 31 Dec 2025

Albergo Etico Roma
Reviewed on 11 Mar 2026
Where to stay in Esquilino

Rome City Centre
Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views.
Top hotels in Esquilino

Napoleon Hotel
The property is old and outdated. More like a 2-star motel, not a 4-star hotel. The balcony was extremely dirty, rust and mold everywhere. Staff was ok.
Reviewed on 16 Apr 2026

NH Collection Roma Palazzo Cinquecento
Great location , staff exceptionally professional ,
Reviewed on 11 Apr 2026

Hotel Aphrodite
The staff were very helpful and nice. The room was always nice and cleaned when we back in our room from Rome exploring. The breakfast buffet was so convenient.
Reviewed on 25 Mar 2026
Frequently asked questions
Popular places to visit
Anfiteatro Castrense
Find out about the history of Rome when you take a trip to Anfiteatro Castrense. Experience the acclaimed art galleries and fascinating museums in this vibrant area.
Villa Giustiniani Massimo
Explore the great outdoors at Villa Giustiniani Massimo, a lovely green space in Rome. Discover the acclaimed art galleries and stunning cathedral in this vibrant area.
Triclinium Leoninum
Find out about the history of Rome with a stop at Triclinium Leoninum. Discover the acclaimed theatre scene and notable monuments in this vibrant area.
Things to do

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Castel Sant’Angelo Entry Ticket and Audioguide
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.













