Eastern Panama Holidays from £1,111

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Your Eastern Panama Holiday

Leave all the planning to us with an Eastern Panama holiday package. With everything organised before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama holiday into reality.

Top Eastern Panama Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Price was £1,543, price is now £1,111 per person
£1,111
per person
23 Oct - 30 Oct
found 1 day ago
Return flight included
Birmingham (BHX) to Panama City (PTY)
9.4/10 Exceptional! (112 reviews)
This is a classic, elegant property that lives up to its reputation. Quality in every regard. On par with some of the finest historic hotels in the country (and I’ve stayed at a few).

Reviewed on 4 Sept 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
Price was £3,237, price is now £2,026 per person
£2,026
per person
23 Oct - 30 Oct
found 1 day ago
Return flight included
Birmingham (BHX) to Panama City (PTY)
No reviews
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was £1,827, price is now £1,150 per person
£1,150
per person
15 Nov - 21 Nov
found 23 hours ago
Return direct flight included
London (LHR) to Panama City (PTY)
9/10 Wonderful! (986 reviews)
The jacuzzi in the room was terrible. Many, many times I tried but could not get it to work. Maintenance came multiple times, but they too had a hard time getting it to work.

Reviewed on 9 Sept 2025

NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Save 100% on your flight
Price was £4,211, price is now £3,075 per person
£3,075
per person
23 Oct - 30 Oct
found 1 day ago
Return flight included
Birmingham (BHX) to Panama City (PTY)
10/10 Exceptional! (54 reviews)
Amazing time across the board staying at both the Treehouse and the Ocean Villa for the week. The attention to the details made this an experience like no other. The treehouse created a one-of-a-kind experience especially with the views and birds around the island. Highly recommend doing both. The service staff were extremely kind and attentive to all needs with a caring spirit of service. The housekeeping staff kept the places immaculate each day. The food quality was exceptional, especially at dinner each night in the Elephant House. The focus and creativity of each meal along with the unique presentation each night really made it special. The soups and main course served each night were absoutely the best we have ever experienced. Our conpliments to the chefs. A special thanks to the staff that made us feel very special and exhibited the gift of hospitality. Outstanding service really shined through Gilberto, Andrea, Mikeal, Franco, Ruby, Carlos, Victor, Liz, Williams, Sherill, and so many others! If you desire an intimate, unique resort experience that you will never forget, this is your place!

Reviewed on 2 Aug 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
Price was £1,825, price is now £1,338 per person
£1,338
per person
23 Oct - 30 Oct
found 1 day ago
Return flight included
Birmingham (BHX) to Panama City (PTY)
9.4/10 Exceptional! (85 reviews)
Beautiful grounds and love the included yoga, meditation, and work outs. They provided free cooked to order breakfast with coffee and juice. Staff was friendly and helpful

Reviewed on 30 Aug 2025

Eastern Panama Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)

Top hotels in Eastern Panama

Hotel Cocotal

Hotel Cocotal

2.5 out of 5
La Guaira, Isla Grande, Provincia de Colón
Fully refundableReserve now, pay when you stay
The price is £72 per night from 15 Sept to 16 Sept
£72
15 Sept - 16 Sept
includes taxes & fees
10/10 Exceptional! (2 reviews)
"It was old, quaint interesting, would recommend"

Reviewed on 5 Sep 2025

Hotel Cocotal
Ciel y Miel

Ciel y Miel

3 out of 5
Caillle Principale, Cacique, Provincia de Colón
10/10 Exceptional! (9 reviews)
"All was good"

Reviewed on 14 Jul 2025

Get rates
Ciel y Miel
Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande, Isla Grande, Colon
10/10 Exceptional! (3 reviews)
"Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special."

Reviewed on 5 Sep 2025

Get rates
Ordovician Beach Resort
See all 172 properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
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Family Friendly Holidays

Frequently asked questions

Can I cancel my flight booking to Eastern Panama due to COVID-19?
Our Customer Service Portal is where you can find useful information about cancelling or changing your flight due to COVID-19. Before booking your tickets, it's wise to scroll through the terms and conditions of your airfare too.
What's the best way to find cheap flights to Eastern Panama that have flexible change policies?
It's as easy as counting to three with Expedia. Firstly, enter your travel details and press "Search." Second step: Check the "No change fee" box under the "Flexible change policies" heading to the left of your screen. Step 3. Nab a cheap and flexible flight to Eastern Panama.
What are some of the general tips for travellers to Eastern Panama during the COVID-19 outbreak?
COVID-19 has resulted in significant changes to the way we travel. If you plan to jet off to Eastern Panama, these tips will help you navigate the "new normal:"
  • Before you lock in a flight, find out if any travel restrictions apply — in both your destination and origin. Keep informed with the latest updates by checking government and travel websites.
  • When you go through airport screening, keep your face mask on. You will be asked to lower it briefly to verify your identity. Passengers who refuse to wear a face mask may face civil penalties and may also be escorted from the building.
  • Rather than handing a TSA agent your boarding pass, position it directly on the reader yourself. Once that's done, hold it up for inspection.
  • TSA now allows passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on bags. This will need to be removed from your bag and presented for screening.
  • To minimize handling during screening, place items such as your phone, keys and wallet into your carry-on instead of the bins.
  • Transport all food items in a clear plastic bag and also place them in a screening bin. Keeping food separate from your carry-on means it's less likely a TSA employee will need to open and touch your bag for inspection.

Which airlines fly to Eastern Panama?
Copa Airlines is a well-known airline servicing Eastern Panama. Search for airfares to Tocumen Intl. Airport (PTY) and you'll have 3173 Copa Airlines flights every month to choose from.
How can I find cheap tickets to Eastern Panama?
You'll always find a fabulous deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred travel date, then click on the flexible dates box above to see prices for nearby days. was the cheapest price for a flight to Eastern Panama in the last seven days.
How much is a flight to Eastern Panama?
There were lots of low-cost fares for the taking in the last seven days, with the cost of a round-trip flight to Eastern Panama varying between and . Many lucky travellers locked in one-way flights from () for only .
What are the most popular airports to fly into in Eastern Panama?
The main gateway to Eastern Panama, roughly 3507 flights land at Tocumen Intl. Airport (PTY) each month. Track down a top deal, book your seat and get ready to enjoy the best of this amazing region.
When is the cheapest time to fly to Eastern Panama?
Jetting off on a Tuesday, followed by a Monday, is generally the best way to land the cheapest fare. Steer clear of the weekend if you can, because Saturday is typically the most expensive day. Spend the dollars you saved having a good time in Eastern Panama instead!
How much is a plane ticket to Eastern Panama?
Prices varied from to over the last seven days. When you're ready to book, we'll be ready to help you pick up the best deal to Eastern Panama.
Which airlines with flights to Eastern Panama employ COVID-19 cleanliness policies?
In order to minimize contact between passengers and cabin crew during the COVID-19 outbreak, the majority of airlines have taken social distancing and other measures to the skies. Just a few of these are:
  • Copa Airlines - this airline is known for conducting passenger temperature checks and electrostatic cleaning.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.