Eastern Panama Holidays from £881
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Eastern Panama Holiday
Leave all the planning to us with an Eastern Panama holiday package. With everything organised before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama holiday into reality.
Top Eastern Panama Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
£1,476
per person
23 Nov - 30 Nov
just found
Return direct flight included
London (LGW) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Such a great experience! I’d recommend it to anyone and love to stay again.
Reviewed on 20 Sept 2026
Eastern Panama Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Tocumen Intl. Airport (PTY) |
Top hotels in Eastern Panama
Ordovician Beach Resort
Isla Grande Isla Grande Colon
£346
23 Sept - 24 Sept
includes taxes & fees
10/10 Exceptional! (14 reviews)
"La comida estaba deliciosa, el staff con excelente atención. La playa privada es un super plus."
Reviewed on 19 Jul 2026
Ranchos de Chalia
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
£96
18 Oct - 19 Oct
includes taxes & fees
9.8/10 Exceptional! (19 reviews)
"Here's a natural, conversational review in English: We had a wonderful stay here. The hotel is beautiful, with an amazing pool overlooking both the ocean and the rainforest. Everything was very clean, and the beds were extremely comfortable. The staff were incredibly friendly and welcoming. The owner ..."
Reviewed on 2 Jun 2026
Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
£154
23 Sept - 24 Sept
includes taxes & fees
10/10 Exceptional! (1 review)
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door."
Reviewed on 15 Mar 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Eastern Panama attractions
Isla Diablo
Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.
Isla Chichime
Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area.
Museum of the Kuna Nation
You can spend an afternoon browsing the exhibits at Museum of the Kuna Nation during your travels in Narganá. Stroll along the seaside or experience the area's festivals.
Porvenir Museum
You can spend time studying the exhibits at Porvenir Museum in Narganá. Amble around the area's seaside or experience its festivals.
Frequently asked questions
How much does an Eastern Panama travel package cost?
Perhaps less than you might think — from as low as £881, actually! By bundling hotels, flights and car rentals into a custom-built package, your Eastern Panama escape is only clicks away.
If I'm not able to travel, can I cancel my Eastern Panama travel package?
Because we understand life can be unpredictable, the answer is yes. To learn more, visit our Customer Service Portal. But generally speaking, if you've booked your Eastern Panama travel package in the last 24 hours, you may be able to change or cancel it with no penalties. Your airline, hotel or car rental company may impose a fee if your booking is older than that.
How do I get a cheap travel package to Eastern Panama?
Combine your bookings with Expedia to save big on your next exciting adventure. With more than 550 airlines and 1,000,000 properties around the globe, your Eastern Panama travel package can be tailored exactly to suit your travel style. With all those extra dollars, why not include some fun experiences and tours? It's an easy way to unlock even more savings. The holiday you've always dreamed of in Eastern Panama is much closer than you thought!
Does Expedia offer Book Now, Pay Later Eastern Panama holidays?
Expedia has partnered with online lender Klarna to make your next break easier on your bank balance. Paying in instalments means you can spread the costs of your next adventure, leaving you with more money to play with while you're away. Klarna has several payment plans to pick from, so you're sure to find something that works with your budget. Check out these flexible payment options:
- Pay monthly holidays: Realise your holiday dreams sooner with Klarna's convenient monthly instalment plans. If paying bite-sized amounts each month works for you, choose this option at checkout.
- Pay in instalments holidays: Like the idea of paying off your holiday in multiple transactions? Consider this Book Now, Pay Later option with Klarna.
- Low deposit holidays: If paying a small percentage of your trip (rather than the full total upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan with Klarna.
How far in advance should I book my Eastern Panama holiday?
Your safest bet is to book early. Air carriers generally release flights up to 12 months in advance, and this is an excellent opportunity to land some of the cheapest prices. Boss just told you to use up some holiday time next week? That's fine too — Expedia are never short on fantastic bargains to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Eastern Panama travel package include?
Much of that is up to you. You can pick from a variety of Eastern Panama packages, such as a flight, rental car and hotel. You can also book a hotel and a flight, or a flight with a rental car. Once you've made your booking, you can add the fun stuff like tours and activities. Whatever your dream Eastern Panama trip looks like, get ready to save!
What should I know before booking an Eastern Panama travel package?
Our prices are always low. However, you'll pick up even more savings if you book your flights, hotels and car rentals together. With an Expedia package, you'll always get transparent pricing and a huge range of choice.
Can I choose my airline with an Eastern Panama Expedia travel package?
With a travel package, you're in charge. Whether you're hoping to fly to Eastern Panama in business or coach, simply select from the available airline options. Expedia has access to more than 550 partner airlines throughout the world.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
