Title: Eastern Panama Holidays 2026 from £783 | Expedia.co.uk [Eastern Panama Travel Guide](https://expedia.co.uk/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Holiday Rentals in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Holiday-Rentals.d6246114.Travel-Guide-HolidayRentals)[Flights to Eastern Panama](https://expedia.co.uk/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Eastern Panama Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Eastern-Panama.d6246114.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Eastern Panama Holidays from £783 ## Book a Hotel + Flight or Car together to unlock savings Photo by Nico Barner - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ### Your Eastern Panama Holiday Leave all the planning to us with an Eastern Panama holiday package. With everything organised before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. [Isla Tigre](https://www.expedia.co.uk/Isla-Tigre.d3000379099.Destination-Travel-Guides) and [Palenque](https://www.expedia.co.uk/Palenque.d553248623282267036.Destination-Travel-Guides) are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama holiday into reality. ## Top Eastern Panama Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites £783 per person 17 Apr - 24 Apr found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 10/10 Exceptional! (1 review) Excellent apartment on a golf resort. 5 Star. Reviewed on 28 Jan 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight £1,201 per person 17 Apr - 24 Apr found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Fast and easy check in. Unfortunately there was a wedding going on, leading to lots of noise and making having breaking or drinks not an option. The room was an upgrade ( paid for) with only a window onto an inside wall. A bit disappointing at 450$ a night . Reviewed on 1 Feb 2026 ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista £947 per person 17 Apr - 24 Apr found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) Everything was great SPECIALLY breakfast Reviewed on 3 Feb 2026 ![La Concordia Boutique Hotel](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3645c5b6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Concordia Boutique Hotel Casco Viejo £1,231 per person 17 Apr - 24 Apr found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 9.6/10 Exceptional! (191 reviews) Great staff. Awesome rooms. The rooftop bar was INCREDIBLE! Highly recommend. Reviewed on 13 Jan 2026 ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Las Americas Golden Tower Panama San Francisco £980 per person 17 Apr - 24 Apr found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 9/10 Wonderful! (1,005 reviews) The Hotel itself is very good, but it’s not being properly managed. The cleaning needs to be better. Reviewed on 1 Feb 2026 ## Eastern Panama Essential Information | Language | Spanish | | --------------- | --------------------------- | | Currency | Panamanian balboas | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Tocumen Intl. Airport (PTY) | ## Top hotels in Eastern Panama ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL ISLA GRANDE Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province Fully refundableReserve now, pay when you stay £84 4 Feb - 5 Feb includes taxes & fees 4.8/10 (5 reviews) Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting ... Reviewed on 19 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=04%2F02%2F2026&endDate=05%2F02%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6246114) ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cocotal La Guaira Isla Grande Provincia de Colón Fully refundableReserve now, pay when you stay £83 4 Feb - 5 Feb includes taxes & fees 9.4/10 Exceptional! (6 reviews) Excelente hospedaje lo mejor la amabilidad de José Ángel y los demás muchachos... Con decirles que hasta te llevan a la habitación si te has tomado algunos tragos.. recomendada al 100 Reviewed on 7 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=04%2F02%2F2026&endDate=05%2F02%2F2026&selected=116789972&PinnedHotelID=116789972&HadPinnedHotel=true®ionId=6246114) ![Konsenda San Blas](https://images.trvl-media.com/lodging/100000000/99080000/99079700/99079675/3f55d468_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Konsenda San Blas Llano Cartí Km 11 El Llano Panamá Province Fully refundableReserve now, pay when you stay 10/10 Exceptional! (1 review) wonderful eco lodge in the forest. Easy to reach by car, just on the main road. Paths to walk, excellent meals. A very good option if you need to relax before and after visiting Sab Blas, but worth the trip on its own, beautiful landscape. Reviewed on 6 Mar 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=17%2F02%2F2026&endDate=18%2F02%2F2026&selected=99079675&PinnedHotelID=99079675&HadPinnedHotel=true®ionId=6246114) [](https://expedia.co.uk/Hotel-Search?startDate=17%2F02%2F2026&endDate=18%2F02%2F2026&selected=99079675&PinnedHotelID=99079675&HadPinnedHotel=true®ionId=6246114) [See all 178 properties in Eastern Panama](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=04%2F02%2F2026&endDate=05%2F02%2F2026®ionId=6246114) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Frequently asked questions ### Can I cancel my flight booking to Eastern Panama due to COVID-19? ### What's the best way to find cheap flights to Eastern Panama that have flexible change policies? ### What are some of the general tips for travellers to Eastern Panama during the COVID-19 outbreak? > - Before you lock in a flight, find out if any travel restrictions apply — in both your destination and origin. Keep informed with the latest updates by checking government and travel websites. > - When you go through airport screening, keep your face mask on. You will be asked to lower it briefly to verify your identity. Passengers who refuse to wear a face mask may face civil penalties and may also be escorted from the building. > - Rather than handing a TSA agent your boarding pass, position it directly on the reader yourself. Once that's done, hold it up for inspection. > - TSA now allows passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on bags. This will need to be removed from your bag and presented for screening. > - To minimize handling during screening, place items such as your phone, keys and wallet into your carry-on instead of the bins. > - Transport all food items in a clear plastic bag and also place them in a screening bin. Keeping food separate from your carry-on means it's less likely a TSA employee will need to open and touch your bag for inspection. ### Which airlines fly to Eastern Panama? ### How can I find cheap tickets to Eastern Panama? ### How much is a flight to Eastern Panama? ### What are the most popular airports to fly into in Eastern Panama? ### When is the cheapest time to fly to Eastern Panama? ### How much is a plane ticket to Eastern Panama? ### Which airlines with flights to Eastern Panama employ COVID-19 cleanliness policies? > - Copa Airlines - this airline is known for conducting passenger temperature checks and electrostatic cleaning. > - United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant. > - American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant. ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app