Eastern Panama Holidays

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Your Eastern Panama Holiday

Leave all the planning to us with an Eastern Panama holiday package. With everything organised before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama holiday into reality.

Eastern Panama Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)

Our pick of the best Eastern Panama Hotel Deals

Ordovician Beach Resort
Ordovician Beach Resort
4.5 out of 5
Isla Grande, Isla Grande, Colon
Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Isla Mamey and Portobelo National ...
Ordovician Beach Resort
Ciel y Miel
Ciel y Miel
3 out of 5
Caillle Principale, Cacique, Provincia de Colón
Stay at this 3-star beach hotel in Cacique. Enjoy free breakfast, free Wi-Fi and free valet parking. Popular attractions Isla Mamey and Portobelo National Park ...
10/10 Exceptional! (4 reviews)
"Is an execelent place to relax, enjoy nice food and view. It has access to a beautiful beach which is not overcrowded and the staff is on top of everything. Me and my family are definetly coming back!!!"

Reviewed on 3 Mar 2025

Ciel y Miel
Private Over the Water Cabin on San Blas Island
Private Over the Water Cabin on San Blas Island
2 out of 5
9.542876, -78.899058, Narganá, San Blas
Stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
6.4/10 (5 reviews)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were ..."

Reviewed on 16 Feb 2022

Private Over the Water Cabin on San Blas Island
See all 159 properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Holidays

All Inclusive Holidays

Beach Holidays

Beach Holidays

Family Friendly Holidays

Family Friendly Holidays

Frequently asked questions

How much does an Eastern Panama travel package cost?
Perhaps less than you might think — from as low as , actually! By bundling hotels, flights and car rentals into a custom-built package, your Eastern Panama escape is only clicks away.
If I'm not able to travel, can I cancel my Eastern Panama travel package?
Because we understand life can be unpredictable, the answer is yes. To learn more, visit our Customer Service Portal. But generally speaking, if you’ve booked your Eastern Panama travel package in the last 24 hours, you may be able to change or cancel it with no penalties. Your airline, hotel or car rental company may impose a fee if your booking is older than that.
How do I get a cheap travel package to Eastern Panama?
Combine your bookings with Expedia to save big on your next exciting adventure. With more than 550 airlines and 1,000,000 properties around the globe, your Eastern Panama travel package can be tailored exactly to suit your travel style. With all those extra dollars, why not include some fun experiences and tours? It’s an easy way to unlock even more savings. The holiday you’ve always dreamed of in Eastern Panama is much closer than you thought!
Does Expedia offer Book Now, Pay Later Eastern Panama holidays?
Expedia has partnered with online lender Klarna to make your next break easier on your bank balance. Paying in instalments means you can spread the costs of your next adventure, leaving you with more money to play with while you’re away. Klarna has several payment plans to pick from, so you’re sure to find something that works with your budget. Check out these flexible payment options:

  • Pay monthly holidays: Realise your holiday dreams sooner with Klarna’s convenient monthly instalment plans. If paying bite-sized amounts each month works for you, choose this option at checkout.
  • Pay in instalments holidays: Like the idea of paying off your holiday in multiple transactions? Consider this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: If paying a small percentage of your trip (rather than the full total upfront) makes it easier to click that “book now” button, opt for a low deposit holiday payment plan with Klarna.

How far in advance should I book my Eastern Panama holiday?
Your safest bet is to book early. Air carriers generally release flights up to 12 months in advance, and this is an excellent opportunity to land some of the cheapest prices. Boss just told you to use up some holiday time next week? That’s fine too — Expedia are never short on fantastic bargains to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Eastern Panama travel package include?
Much of that is up to you. You can pick from a variety of Eastern Panama packages, such as a flight, rental car and hotel. You can also book a hotel and a flight, or a flight with a rental car. Once you’ve made your booking, you can add the fun stuff like tours and activities. Whatever your dream Eastern Panama trip looks like, get ready to save!
What should I know before booking an Eastern Panama travel package?
Our prices are always low. However, you’ll pick up even more savings if you book your flights, hotels and car rentals together. With an Expedia package, you’ll always get transparent pricing and a huge range of choice.
Can I choose my airline with an Eastern Panama Expedia travel package?
With a travel package, you’re in charge. Whether you’re hoping to fly to Eastern Panama in business or coach, simply select from the available airline options. Expedia has access to more than 550 partner airlines throughout the world.

Discover the most popular places to visit in Eastern Panama

Cayos Holandeses

Commune with nature and explore the great outdoors at Cayos Holandeses during your travels in San Blas Islands. Stroll along the seaside or experience the area's festivals.

Cayos Holandeses

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.