Title: Holiday Rentals Eastern Panama from £83: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk

[Eastern Panama Travel Guide](https://expedia.co.uk/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Flights to Eastern Panama](https://expedia.co.uk/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.co.uk/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Eastern-Panama.d6246114.Car-Hire-Guide)[Eastern Panama Holidays](https://expedia.co.uk/Eastern-Panama.d6246114.Holidays-City-Breaks)

![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience  a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. 
#BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Nico Barner

![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-02-06&endDate=2026-02-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[17 Apr - 19 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[15 May - 17 May](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Eastern Panama holiday rentals

![Property grounds](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/99016f78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, white sand](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/4c6cabd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/749a0f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/f4818252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Blas Private Beach Cabin

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information)

Narganá

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information)

![Boating](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/fad9e47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/b620dae0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/edcd0ecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/1c15e003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Blas Private Oceanfront Cabin

[](https://www.expedia.co.uk/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information)

Narganá

£287

includes taxes & fees

22 Jan - 23 Jan

[](https://www.expedia.co.uk/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information)

![Dock](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/533ab64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin | Beach/ocean view](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/4fa56cde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/4091b21d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/749003b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Over-Water Cabins on San Blas Island

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-Prvt-Beach-Cabins-In-San-Blas-Islands.h46949355.Hotel-Information)

Narganá

£246

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-Prvt-Beach-Cabins-In-San-Blas-Islands.h46949355.Hotel-Information)

![Outdoor pool, a natural pool](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/6e039867.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sun deck](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/6726e101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | Desk, bed sheets](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/7d6772aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | Private kitchen | Fridge, oven, stovetop, toaster](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/9c1f138a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Over-the-Water Cabin in San Blas including Meals

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-San-Blas-Prvt-Sailboat-Island-Hopping.h40916962.Hotel-Information)

Mirladub

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-San-Blas-Prvt-Sailboat-Island-Hopping.h40916962.Hotel-Information)

![Basic Cabin, Multiple Beds, Balcony, Sea View | Beach/ocean view](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/5e4a77e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin, Multiple Beds, Balcony, Sea View | Bathroom | Separate bathtub and shower, toilet paper](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/0c7c55ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/d4916902.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/e1ca9c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Blas Tour Aridub

[](https://www.expedia.co.uk/San-Blas-Tour-Aridub.h107987054.Hotel-Information)

Narganá

£185

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/San-Blas-Tour-Aridub.h107987054.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/1649bd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/7ad3ced9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/07d64ddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/4fd01df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabaña La Punta op het Strand!!

[](https://www.expedia.co.uk/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information)

Colón Province

£130

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/803cd264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/b3c05fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/c41bafb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/1b7d8cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Catamaran experience in paradise

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information)

Guna Yala Comarca

£894

includes taxes & fees

23 Jan - 24 Jan

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/0b910251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, stovetop, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/bb4bcbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/w1296h891x0y0-1b08f53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/6da56f2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

[](https://www.expedia.co.uk/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information)

Guna Yala Comarca

£739

includes taxes & fees

28 Jan - 29 Jan

[](https://www.expedia.co.uk/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information)

![Beach nearby, beach towels](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/a2a99590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/6f230b81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/da467749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/07d1058d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Exclusive sailboat for 2 people all inclusive in San Blas islands

[](https://www.expedia.co.uk/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information)

Guna Yala

10/10

Exceptional

(1 review)

"Anita e Federico sono state il valore aggiunto in queste isole meravigliose. La loro disponibilita, le loro attenzioni, i sorridenti contatti di Anita con la popolazione dei Guna e la cucina superlativa di Federico hanno reso speciale la nostra vacanza che ha soddisfatto appieno le nostre aspettative. Discreta e deliziosa la presenza della gattina (la principessa di bordo) Shanu. Grazie di tutto!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Grazia B.

£458

includes taxes & fees

26 Jan - 27 Jan

[](https://www.expedia.co.uk/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information)

![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/1e44d7b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/fef7062f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/a6aae70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Despierta sobre el mar 

[](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information)

Garrote

6.0/10

(1 review)

£83

includes taxes & fees

23 Jan - 24 Jan

[](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/ddaf5491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/9dbdc819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/d99ec888.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, fireplace](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/a9525fbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Caribbean getaway: beach cottage just on the sand

[](https://www.expedia.co.uk/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information)

Palenque

10/10

Exceptional

(1 review)

"The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beth N.

£227

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/66a17c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/551ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/30f0b989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deluxe Beachfront 4-bedroom house in Colón Province

[](https://www.expedia.co.uk/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information)

Colón Province

£293

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/fa337c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/d70c8750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/b2886ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/93d05a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private cabin in San Blas

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information)

Panama , Betania

£222

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information)

![Boating](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/b3b793d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/268dce26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/d29880fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/f7f8513a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Blas Private Over-the-Water Cabin

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-San-Blas-Private-Over-The-Water-Cabin.h46949679.Hotel-Information)

Narganá

8.0/10

Very good

(2 reviews)

"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

[](https://www.expedia.co.uk/San-Blas-Islands-Hotels-San-Blas-Private-Over-The-Water-Cabin.h46949679.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/1f45d7b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/38938e50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/810fb7dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/d2331d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Jacuzy, pool and lake at the same house.

[](https://www.expedia.co.uk/The-House-Is-Beautiful-But-De-Best-Is-The-Lake-To-Do-Fishing.h45022806.Hotel-Information)

Colon

10/10

Exceptional

(1 review)

"Great. Please take care of the cat"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

KENNETH E.

£55

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/The-House-Is-Beautiful-But-De-Best-Is-The-Lake-To-Do-Fishing.h45022806.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/eefeb662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/bc739ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/f4e54b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast meal](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/23dccb12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming cottage with 2 separate beds and a beautiful view of the river

[](https://www.expedia.co.uk/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information)

Santa Rosa

10/10

Exceptional

(1 review)

"Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank."

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Birgit U.

£112

includes taxes & fees

22 Jan - 23 Jan

[](https://www.expedia.co.uk/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/3d98011b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/7123cf2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/a0ff3f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/e05e8ef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elegance and comfort in old town panama

[](https://www.expedia.co.uk/24-De-Diciembre-Hotels-Vrbo-Property.h114691452.Hotel-Information)

Panamá

£70

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/24-De-Diciembre-Hotels-Vrbo-Property.h114691452.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/f538191e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/bae0d59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/617e1c47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/5cf47d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tranquil cabin with WiFi in Los Altos de Cerro Azul

[](https://www.expedia.co.uk/Caimitillo-Hotels-Tranquil-Cabin-With-WiFi-In-Los-Altos-De-Cerro-Azul.h114220227.Hotel-Information)

Los Altos de Cerro Azul

£152

includes taxes & fees

23 Jan - 24 Jan

[](https://www.expedia.co.uk/Caimitillo-Hotels-Tranquil-Cabin-With-WiFi-In-Los-Altos-De-Cerro-Azul.h114220227.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/9bf6774d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/ac93b6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/bde6b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/ea8360be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

[](https://www.expedia.co.uk/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information)

Maria Chiquita

6.8/10

(3 reviews)

"Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Will

£111

includes taxes & fees

21 Jan - 22 Jan

[](https://www.expedia.co.uk/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information)

![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/w1064h805x0y11-7ae51d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books, stereo](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/ad3a9028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/5a781682_edited_8afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/252623d6_edited_e05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### BEAUTIFUL APARTMENT IN FRONT OF THE SEA

[](https://www.expedia.co.uk/Portobelo-Hotels-BEAUTIFUL-APARTMENT-IN-FRONT-OF-THE-SEA.h74054867.Hotel-Information)

Portobelo

8.0/10

Very good

(3 reviews)

"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rosa M.

£135

includes taxes & fees

22 Jan - 23 Jan

[](https://www.expedia.co.uk/Portobelo-Hotels-BEAUTIFUL-APARTMENT-IN-FRONT-OF-THE-SEA.h74054867.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04&regionId=6246114&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find holiday rentals that suit your style

Apartments

[](https://www.expedia.co.uk/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=APARTMENT)

Villas

[](https://www.expedia.co.uk/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=VILLA)

Condos

[](https://www.expedia.co.uk/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=CONDO)

Private holiday homes

[](https://www.expedia.co.uk/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=VACATION_HOME)

Cottages

[](https://www.expedia.co.uk/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=COTTAGE)

Houseboats

[](https://www.expedia.co.uk/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=HOUSE_BOAT)

Cabins

[](https://www.expedia.co.uk/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-04-20&d1=2026-04-20&endDate=2026-04-23&d2=2026-04-23&lodging=CABIN)

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## Top Eastern Panama Hotel Reviews

![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg)

### Hotel Cocotal

10/10 Excellent

"Excelente hospedaje lo mejor la amabilidad de José Ángel y los demás muchachos... Con decirles que hasta te llevan a la habitación si te has tomado algunos tragos.. recomendada al 100"

[](https://expedia.co.uk/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information)

![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0_y.jpg)

### Ranchos de Chalia

10/10 Excellent

"Beautiful tranquility in nature, amazing staff"

[](https://expedia.co.uk/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information)

![Caribbean getaway: beach cottage just on the sand](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/24e34d16_y.jpg)

### Caribbean getaway: beach cottage just on the sand

10/10 Excellent

"The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. "

[](https://expedia.co.uk/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information)

![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg)

### HOTEL ISLA GRANDE 

6/10 Okay

"Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting until 5 am. There are no amenities however the caribbean ocean is just outside the door. "

[](https://expedia.co.uk/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information)

![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041_y.jpg)

### Ordovician Beach Resort

10/10 Excellent

"Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special."

[](https://expedia.co.uk/Ordovician-Beach-Resort.h103761591.Hotel-Information)

![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg)

### Private Over the Water Cabin on San Blas Island

10/10 Excellent

"Very nice. And I liked the food "

[](https://expedia.co.uk/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information)

![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3_y.jpg)

### Ciel y Miel 

10/10 Excellent

"All was good "

[](https://expedia.co.uk/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information)

## Find out more about Eastern Panama

**Everything you need to know about** **Eastern Panama** **holiday rentals**

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Panama holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Panama holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Eastern Panama holiday rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Eastern Panama. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Eastern Panama holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Eastern Panama holiday rentals we have selected for you start as low as £83 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Eastern Panama rentals**

At Expedia, we put the best Eastern Panama holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Eastern Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Panama holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

## Explore a world of travel with Expedia

- Trending destinations on Expedia.co.uk
- All accommodation types in Eastern Panama

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- [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations)
- [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations)

- [Holiday Homes in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Private-Holiday-Homes.d6246114-aaPrivateHolidayHomes.Travel-Guide-Accommodation)
- [Apartments in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Apartments.d6246114-aaApartments.Travel-Guide-Accommodation)
- [Houseboats in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Houseboats.d6246114-aaHouseboats.Travel-Guide-Accommodation)
- [Cabin Rentals in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Cabins.d6246114-aaCabins.Travel-Guide-Accommodation)
- [Lodges in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Lodges.d6246114-aaLodges.Travel-Guide-Accommodation)
- [Villas in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Villas.d6246114-aaVillas.Travel-Guide-Accommodation)
- [B&B in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Bed-And-Breakfasts.d6246114-aaBedAndBreakfasts.Travel-Guide-Accommodation)
- [Cottages in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Cottages.d6246114-aaCottages.Travel-Guide-Accommodation)
- [Hostels in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Hostels.d6246114-aaHostels.Travel-Guide-Accommodation)
- [Condo Rentals in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Condos.d6246114-aaCondos.Travel-Guide-Accommodation)
- [Caravan Parks in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Caravan-Parks.d6246114-aaCaravanParks.Travel-Guide-Accommodation)
- [Farmstay in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Agritourism.d6246114-aaAgritourism.Travel-Guide-Accommodation)
- [Resorts in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Hotel-Resorts.d6246114-aaHotelResorts.Travel-Guide-Accommodation)
- [Guest Houses in Eastern Panama ](https://expedia.co.uk/Eastern-Panama-Guest-Houses.d6246114-aaGuestHouses.Travel-Guide-Accommodation)

### Expedia's Latest Trends

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- [Flights to Isla Colon](https://expedia.co.uk/Cheap-Flights-To-Isla-Colon.d6347742.Travel-Guide-Flights)

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- [Car rental in Panama City](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-City.d2897.Car-Hire-Guide)

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General

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- [Visit Panama City](https://expedia.co.uk/Panama-City.dx2897)
- [Visit Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone.dx6222968)

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