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Top Holiday Rentals in Eastern Panama

Private Over the Water Cabin on San Blas Island
Aerial view
Private Over the Water Cabin on San Blas Island
2.0 star property
6.4 out of 10, (5)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were off hinge and barely closed. The shower and sink were filthy and the toilet stained. The water smelled strongly of sulpher so we did not shower nor use it for anything other than a hand wash. Food was...
Private Over the Water Cabin on San Blas Island
Casa Anzuelo is an oceanfront home that is all about the water and nature.
Beach | Beach nearby, sun-loungers, beach towels
Casa Anzuelo is an oceanfront home that is all about the water and nature.
10.0 out of 10, Exceptional, (12)
"The house and the property were very well managed, the accommodations also met my needs very well. Casa Anzuelo is a place to escape from the world, so if your goal is a peaceful place to read, think and enjoy the ocean & the warmth of the weather, then this is the place for you. Jim, the owner, was great to speak with regarding everything in the area as well as the background and history of Panama, and was willing to assist or help in anything that you needed. A great host!"
Casa Anzuelo is an oceanfront home that is all about the water and nature.
Paradise Over the Water Cabins in San Blas
Exterior
Paradise Over the Water Cabins in San Blas
2.5 star property
6.0 out of 10, (1)
"29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the first night we want to leave so bad. The island is not so bad its peaceful and claim but after the bites we could take it we were prepared with bug spray but it was not enough for the bugs. The island...
Paradise Over the Water Cabins in San Blas
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San Blas Private Oceanfront Cabin
On the beach, white sand
San Blas Private Oceanfront Cabin
2.5 star property
The price is £302
includes taxes & fees
2 Jun - 3 Jun
San Blas Private Oceanfront Cabin
Private Over-Water Cabins on San Blas Island
Aerial view
Private Over-Water Cabins on San Blas Island
2.5 star property
The price is £259
includes taxes & fees
1 Jun - 2 Jun
Private Over-Water Cabins on San Blas Island
San Blas Private Over-the-Water Cabin
On the beach, white sand, snorkelling, beach bar
San Blas Private Over-the-Water Cabin
2.5 star property
8.0 out of 10, Very good, (2)
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...
The price is £319
includes taxes & fees
12 Jun - 13 Jun
San Blas Private Over-the-Water Cabin
Casa Frente al Mar - Isla Grande
Pool
Casa Frente al Mar - Isla Grande
10.0 out of 10, Exceptional, (1)
"All perfect "
Casa Frente al Mar - Isla Grande
Paraiso de Ensueño Caribeño
Beach
Paraiso de Ensueño Caribeño
10.0 out of 10, Exceptional, (1)
"Es un paraiso con aguas cristalinas, vista increible y las instalaciones de la casa, lo hacen sentir a uno como en casa. Su personal de atencio en sitio, siempre fue muy amable y estuvieron pendientes que no nos hiciera falta nada."
The price is £343
includes taxes & fees
9 Jun - 10 Jun
Paraiso de Ensueño Caribeño
Catamaran experience in paradise
Aerial view
Catamaran experience in paradise
The price is £896
includes taxes & fees
1 Jun - 2 Jun
Catamaran experience in paradise
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
Pool
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
10.0 out of 10, Exceptional, (29)
"A beautiful beachfront property with hammocks, snorkeling, kayaks and a lovely staff to prepare meals made this the ideal location for our family Christmas holiday."
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
A fantastic place between the sea and the jungle
Interior
A fantastic place between the sea and the jungle
10.0 out of 10, Exceptional, (3)
"It was a pleasure to stay there. I´ve been twoo times this year, good weather and no mosquitos. nature as momkey around and be apart of the city for a while. It is a pretty much good choice. just ensure to go in 4x4 car and bring whole food and drinks for your stay. 30 min at least to reach a place to buy sth."
A fantastic place between the sea and the jungle
Cara al mar Cacique
Aerial view
Cara al mar Cacique
Cara al mar Cacique
Pebos Reef with amazing terrace over the sea - apartment #1
Property grounds
Pebos Reef with amazing terrace over the sea - apartment #1
Pebos Reef with amazing terrace over the sea - apartment #1
SHAULA 5 STARS LUXURY CHARTER SAN BLAS
Aerial view
SHAULA 5 STARS LUXURY CHARTER SAN BLAS
SHAULA 5 STARS LUXURY CHARTER SAN BLAS
San Blas Private Beach Cabin
On the beach, white sand
San Blas Private Beach Cabin
2.5 star property
The price is £302
includes taxes & fees
6 Jun - 7 Jun
San Blas Private Beach Cabin
Private Over-the-Water Cabin in San Blas including Meals
Outdoor pool, a natural pool
Private Over-the-Water Cabin in San Blas including Meals
2.5 star property
The price is £462
includes taxes & fees
6 Jun - 7 Jun
Private Over-the-Water Cabin in San Blas including Meals
Private cabin in San Blas
Beach
Private cabin in San Blas
The price is £238
includes taxes & fees
5 Jun - 6 Jun
Private cabin in San Blas
San Blas Private Sailboat - Island Hopping
On the beach, white sand
San Blas Private Sailboat - Island Hopping
3.0 star property
San Blas Private Sailboat - Island Hopping
FULL PRIVACY HOUSE SURROUNDED BY TREES, FEW STEPS AWAY FROM THE CARIBBEAN SEA
Beach
FULL PRIVACY HOUSE SURROUNDED BY TREES, FEW STEPS AWAY FROM THE CARIBBEAN SEA
FULL PRIVACY HOUSE SURROUNDED BY TREES, FEW STEPS AWAY FROM THE CARIBBEAN SEA
- SV La Francesca - san blas paradise on bord of private sailboat
Pool
- SV La Francesca - san blas paradise on bord of private sailboat
- SV La Francesca - san blas paradise on bord of private sailboat
Don't see what you're looking for?
See all available properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Eastern Panama Holiday Rental Travel Info

Popular accommodation
Eastern Panama house boats
International airport
Panama City (PTY-Tocumen Intl.)

Other types of properties in Eastern Panama you may be interested in

Private Over the Water Cabin on San Blas Island
Aerial view
Private Over the Water Cabin on San Blas Island
2.0 star property
6.4 out of 10, (5)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were off hinge and barely closed. The shower and sink were filthy and the toilet stained. The water smelled strongly of sulpher so we did not shower nor use it for anything other than a hand wash. Food was...
Private Over the Water Cabin on San Blas Island
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Aerial view
San Blas Paradise Private Cabins on Shipwreck Island - meals included
2.0 star property
The price is £154
includes taxes & fees
3 Jun - 4 Jun
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Casa Anzuelo is an oceanfront home that is all about the water and nature.
Beach | Beach nearby, sun-loungers, beach towels
Casa Anzuelo is an oceanfront home that is all about the water and nature.
10.0 out of 10, Exceptional, (12)
"The house and the property were very well managed, the accommodations also met my needs very well. Casa Anzuelo is a place to escape from the world, so if your goal is a peaceful place to read, think and enjoy the ocean & the warmth of the weather, then this is the place for you. Jim, the owner, was great to speak with regarding everything in the area as well as the background and history of Panama, and was willing to assist or help in anything that you needed. A great host!"
Casa Anzuelo is an oceanfront home that is all about the water and nature.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Eastern Panama holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Panama holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Panama holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Eastern Panama holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Eastern Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Eastern Panama holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Eastern Panama holiday rentals we have selected for you start as low as £242 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Eastern Panama rentals

At Expedia, we put the best Eastern Panama holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Eastern Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Panama holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Recent reviews of Eastern Panama properties
Expedia verified reviews

Casa Anzuelo is an oceanfront home that is all about the water and nature.

Casa Anzuelo is an oceanfront home that is all about the water and nature.

5/5 Excellent
Northern Panama Getaway
"The house and the property were very well managed, the accommodations also met my needs very well. Casa Anzuelo is a place to escape from the world, so if your goal is a peaceful place to read, think and enjoy the ocean & the warmth of the weather, then this is the place for you. Jim, the owner, was great to speak with regarding everything in the area as well as the background and history of Panama, and was willing to assist or help in anything that you needed. A great host!"
A verified traveller stayed at Casa Anzuelo is an oceanfront home that is all about the water and nature.
Posted 4 months ago
Casa Anzuelo is an oceanfront home that is all about the water and nature.