Title: Eastern Panama Travel Guide: Best of Eastern Panama, Panama Travel 2026 | Expedia.co.uk [Hotels in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Holiday Rentals in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Holiday-Rentals.d6246114.Travel-Guide-HolidayRentals)[Flights to Eastern Panama](https://expedia.co.uk/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.co.uk/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Eastern-Panama.d6246114.Car-Hire-Guide)[Eastern Panama Holidays](https://expedia.co.uk/Eastern-Panama.d6246114.Holidays-City-Breaks) # Eastern Panama Travel Guide ## Tourist Guide ![Eastern Panama](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/482903472e1439a493a2dee83b010272.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/3d9eeb9430a538d415835dae66f32e6b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/e91e7dd2d90ea5b24911aac1bf6211b5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/af03951a059f7966fe092201856ba764.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Eastern Panama Things to do - Top hotels in Eastern Panama - Top Holiday Rentals in Eastern Panama ![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ordovician Beach Resort Isla Grande Isla Grande Colon Stay at this luxury resort in Isla Grande. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Isla Mamey and Portobelo National Park are ... 10/10 Exceptional! (3 reviews) Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special. Reviewed on 5 Sept 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=26%2F01%2F2026&endDate=27%2F01%2F2026&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true®ionId=6246114) [](https://expedia.co.uk/Hotel-Search?startDate=26%2F01%2F2026&endDate=27%2F01%2F2026&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true®ionId=6246114) ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL ISLA GRANDE Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province £86 13 Jan - 14 Jan includes taxes & fees Stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale and on-site spa services. Popular attractions Isla Mamey and Portobelo National ... 4.8/10 (5 reviews) Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting ... Reviewed on 19 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=13%2F01%2F2026&endDate=14%2F01%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6246114) ![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ranchos de Chalia Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón £89 21 Jan - 22 Jan includes taxes & fees Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ... 9.6/10 Exceptional! (13 reviews) Beautiful tranquility in nature, amazing staff Reviewed on 23 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=21%2F01%2F2026&endDate=22%2F01%2F2026&selected=105443903&PinnedHotelID=105443903&HadPinnedHotel=true®ionId=6246114) [See all 177 properties in Eastern Panama](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=13%2F01%2F2026&endDate=14%2F01%2F2026®ionId=6246114) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![San Blas Private Beach Cabin](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/a97a9ec2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Private Beach Cabin Nusatupo Narganá Guna Yala Stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale and an airport shuttle (surcharge). Popular attractions Museum of the Kuna Nation and ... [](https://expedia.co.uk/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information) ![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Over the Water Cabin on San Blas Island 9.542876, -78.899058 Narganá San Blas Stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale and an airport shuttle (surcharge). Popular attractions Isla Chichime and ... 7/10 Good! (6 reviews) Very nice. And I liked the food Reviewed on 14 Aug 2025 [](https://expedia.co.uk/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ![San Blas Tour Aridub](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/d4916902_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Tour Aridub Urgandi, Guna Yala, Panamá Narganá Guna Yala Stay at this beach cabin in Narganá. Enjoy beach cabanas (surcharge), a beach shuttle (surcharge) and daily housekeeping. [](https://expedia.co.uk/San-Blas-Tour-Aridub.h107987054.Hotel-Information) [See all properties in Eastern Panama](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6246114&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Eastern Panama hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-01-12&endDate=2026-01-13)[12 Jan - 13 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-01-12&endDate=2026-01-13) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-01-13&endDate=2026-01-14)[13 Jan - 14 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-01-13&endDate=2026-01-14) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026)[16 Jan - 18 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026)[23 Jan - 25 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026) ### Popular places to visit ![Isla Diablo](https://mediaim.expedia.com/destination/2/a97b784f0974336e0e332fb195502e82.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Isla Diablo Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.co.uk/Isla-Diablo-Nargana.d951034527519002624.Attraction) #### Museum of the Kuna Nation You can spend an afternoon browsing the exhibits at Museum of the Kuna Nation during your travels in Narganá. Stroll along the seaside or experience the area's festivals. [](https://expedia.co.uk/Museum-Of-The-Kuna-Nation-San-Blas-Islands.d553248621579133546.Attraction) #### Isla Chichime Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.co.uk/Isla-Chichime-Nargana.d951034147716386816.Attraction) ## Cities near Eastern Panama ![San Blas Islands](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### San Blas Islands - Cities near Eastern Panama - Places of interest [San Blas Islands](https://expedia.co.uk/San-Blas-Islands.dx6024116)[Puerto Lindo](https://expedia.co.uk/Puerto-Lindo.dx3000007427)[Isla Tigre](https://expedia.co.uk/Isla-Tigre.dx3000379099)[La Guaira](https://expedia.co.uk/La-Guaira.dx3000439511) - [Cayos Holandeses ](https://expedia.co.uk/Cayos-Holandeses-Guna-Yala.d553248621579133545.Attraction) - [Colon Free Zone ](https://expedia.co.uk/Colon-Free-Zone-Barrio-Sur.d6078503.Attraction) - [Darien National Park ](https://expedia.co.uk/Darien-National-Park-Panama.d6078494.Attraction) - [Limon Bay ](https://expedia.co.uk/Limon-Bay-Colon.d6035251.Attraction) - [Área Silvestre de Narganá ](https://expedia.co.uk/Area-Silvestre-De-Nargana-Panama-Province.d553248621532964873.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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