Title: Eastern Panama Travel Guide: Best of Eastern Panama, Panama Travel 2025 | Expedia.co.uk [Hotels in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Holiday Rentals in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Holiday-Rentals.d6246114.Travel-Guide-HolidayRentals)[Flights to Eastern Panama](https://expedia.co.uk/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.co.uk/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Eastern-Panama.d6246114.Car-Hire-Guide)[Eastern Panama Holidays](https://expedia.co.uk/Eastern-Panama.d6246114.Holidays-City-Breaks) # Eastern Panama Travel Guide ## Tourist Guide ![Eastern Panama](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/482903472e1439a493a2dee83b010272.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/3d9eeb9430a538d415835dae66f32e6b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/e91e7dd2d90ea5b24911aac1bf6211b5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Eastern Panama](https://mediaim.expedia.com/destination/1/af03951a059f7966fe092201856ba764.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Eastern Panama Things to do - Top hotels in Eastern Panama - Top Holiday Rentals in Eastern Panama ![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/20f9a672_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ordovician Beach Resort Isla Grande, Isla Grande, Colon Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Isla Mamey and Portobelo National ... 10/10 Exceptional! (3 reviews) "Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special." Reviewed on 5 Sept 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=27%2F10%2F2025&endDate=28%2F10%2F2025&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true®ionId=6246114) [](https://expedia.co.uk/Hotel-Search?startDate=27%2F10%2F2025&endDate=28%2F10%2F2025&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true®ionId=6246114) ![ San Blas Paradise Private Cabins on Shipwreck Island - meals included](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/7a4cf19e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Paradise Private Cabins on Shipwreck Island - meals included Perro Island, Narganá, Guna Yala Stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale and an airport shuttle (surcharge). Popular attractions Isla Diablo and Isla ... [Get rates](https://expedia.co.uk/Hotel-Search?startDate=27%2F10%2F2025&endDate=28%2F10%2F2025&selected=37804534&PinnedHotelID=37804534&HadPinnedHotel=true®ionId=6246114) [](https://expedia.co.uk/Hotel-Search?startDate=27%2F10%2F2025&endDate=28%2F10%2F2025&selected=37804534&PinnedHotelID=37804534&HadPinnedHotel=true®ionId=6246114) ![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Ocean-Front Cabin with private bathroom on San Blas Island Diablo Island, Narganá, Guna Yala Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge) and a garden. Popular attractions Isla Diablo and Isla Chichime ... [Get rates](https://expedia.co.uk/Hotel-Search?startDate=27%2F10%2F2025&endDate=28%2F10%2F2025&selected=37766985&PinnedHotelID=37766985&HadPinnedHotel=true®ionId=6246114) [](https://expedia.co.uk/Hotel-Search?startDate=27%2F10%2F2025&endDate=28%2F10%2F2025&selected=37766985&PinnedHotelID=37766985&HadPinnedHotel=true®ionId=6246114) [See all 176 properties in Eastern Panama](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=14%2F10%2F2025&endDate=15%2F10%2F2025®ionId=6246114) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Over the Water Cabin on San Blas Island 9.542876, -78.899058, Narganá, San Blas Stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale and an airport shuttle (surcharge). Popular attractions Isla Chichime and ... 7/10 Good! (6 reviews) "Very nice. And I liked the food" Reviewed on 14 Aug 2025 [](https://expedia.co.uk/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ![BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES](https://images.trvl-media.com/lodging/31000000/30800000/30792300/30792236/afc188ba_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES Santa Isabel, Colon Stay at this beach villa in Palenque. Enjoy free Wi-Fi, a beach locale and breakfast (surcharge). Beautiful property "The property was stunning and the staff was amazing. Every meal prepared by the staff was better than the next." Reviewed on 31 Jan 2025 [](https://expedia.co.uk/Palenque-Hotels-Palenque-Spectacular-Caribbean-Ocean-Front-Property-In-Panama.h30792236.Hotel-Information) ![ Paradise Over the Water Cabins in San Blas](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/fe0394dd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Paradise Over the Water Cabins in San Blas G4V2 48, Narganá, Guna Yala Stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale and an airport shuttle (surcharge). Popular attractions Porvenir Museum and ... "29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the ..." Reviewed on 4 Sept 2022 [](https://expedia.co.uk/El-Porvenir-Hotels-Newly-Built-Paradise-Cabins-In-San-Blas.h46948372.Hotel-Information) [See all properties in Eastern Panama](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6246114&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Eastern Panama hotel availability [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-13&endDate=2025-10-14) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-13&endDate=2025-10-14) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-13&endDate=2025-10-14) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-13&endDate=2025-10-14)[13 Oct - 14 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-13&endDate=2025-10-14) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-14&endDate=2025-10-15) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-14&endDate=2025-10-15) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-14&endDate=2025-10-15) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-14&endDate=2025-10-15)[14 Oct - 15 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2025-10-14&endDate=2025-10-15) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [This weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025)[17 Oct - 19 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [Next weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025)[24 Oct - 26 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) ### Popular places to visit ![Isla Diablo](https://mediaim.expedia.com/destination/2/a97b784f0974336e0e332fb195502e82.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Isla Diablo Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.co.uk/Isla-Diablo-Nargana.d951034527519002624.Attraction) #### Museum of the Kuna Nation You can spend an afternoon browsing the exhibits at Museum of the Kuna Nation during your travels in Masargantupo. Stroll along the seaside or experience the area's festivals. [](https://expedia.co.uk/Museum-Of-The-Kuna-Nation-San-Blas-Islands.d553248621579133546.Attraction) #### Isla Chichime Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.co.uk/Isla-Chichime-Nargana.d951034147716386816.Attraction) ## Cities near Eastern Panama ![San Blas Islands](https://mediaim.expedia.com/destination/1/5d18772a3c60968c8280d6082bb3d1e6.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### San Blas Islands [](https://expedia.co.uk/San-Blas-Islands.dx6024116) - Cities near Eastern Panama - Places of interest [San Blas Islands](https://expedia.co.uk/San-Blas-Islands.dx6024116)[Puerto Lindo](https://expedia.co.uk/Puerto-Lindo.dx3000007427)[Isla Tigre](https://expedia.co.uk/Isla-Tigre.dx3000379099)[La Guaira](https://expedia.co.uk/La-Guaira.dx3000439511) - [Cayos Holandeses](https://expedia.co.uk/Cayos-Holandeses-Guna-Yala.d553248621579133545.Attraction) - [Colon Free Zone](https://expedia.co.uk/Colon-Free-Zone-Barrio-Sur.d6078503.Attraction) - [Darien National Park](https://expedia.co.uk/Darien-National-Park-Panama.d6078494.Attraction) - [Limon Bay](https://expedia.co.uk/Limon-Bay-Colon.d6035251.Attraction) - [Área Silvestre de Narganá](https://expedia.co.uk/Area-Silvestre-De-Nargana-Panama-Province.d553248621532964873.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)