Title: Top Hotels in New Madrid County - Compare New Madrid County Hotels | Expedia.co.uk [Holiday Rentals in New Madrid County](https://expedia.co.uk/Destinations-In-New-Madrid-County.d553248635976433157.Holiday-Rental-Destinations)[New Madrid County Car Hire](https://expedia.co.uk/Destinations-In-New-Madrid-County.d553248635976433157.Car-Hire-Destinations)[New Madrid County Holidays](https://expedia.co.uk/New-Madrid-County.d553248635976433157.Holidays-City-Breaks) ![The best restaurant I have EVER been to! Hands down!!!](https://images.trvl-media.com/place/553248634983441802/03fb167a-d590-4293-9dd9-648c99605c85.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Coleman # Find the best New Madrid County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in New Madrid County Pool [](https://www.expedia.co.uk/Hotel-Search?destination=New+Madrid+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433157&latLong=36.594583%2C-89.651746&adults=2&startDate=2025-12-08&d1=2025-12-08&endDate=2025-12-10&d2=2025-12-10&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=New+Madrid+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433157&latLong=36.594583%2C-89.651746&adults=2&startDate=2025-12-08&d1=2025-12-08&endDate=2025-12-10&d2=2025-12-10&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=New+Madrid+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433157&latLong=36.594583%2C-89.651746&adults=2&startDate=2025-12-08&d1=2025-12-08&endDate=2025-12-10&d2=2025-12-10&amenities=PETS) ## New Madrid County Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Sikeston [](https://expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) ## Check prices for these dates Tonight [24 Nov - 25 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433157&startDate=2025-11-24&endDate=2025-11-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [25 Nov - 26 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433157&startDate=2025-11-25&endDate=2025-11-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433157&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433157&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels New Madrid County ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1003) "Clean room, great location and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £84 includes taxes & fees 29 Nov - 30 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1004) "Everything was clean, staff was friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £68 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f00e1c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/5e8a3e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston Sikeston 7.2/10 Good (1004) "A great stay in every aspect. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gertrude £55 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 9.0/10 Wonderful (429) "Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doncheial £82 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1004) "Very convenient and great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duwaine £69 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (711) "Stayed one night. Good rate for the Hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £56 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/06367e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Bathroom | Combined shower/bathtub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville Portageville 8.0/10 Very good (723) "Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger [](https://www.expedia.co.uk/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.2/10 Wonderful (37) "THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) AHMAD £95 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d663210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/0acd5e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking (Mobility, Roll-in Shower) | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/a7ce909b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/e6403655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 By Wyndham Marston Marston 7.8/10 Good (36) "Todo excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Lirra Diaz £46 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/dda7050d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area Sikeston 6.6/10 (560) "The room was good a/c kept it cold " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £50 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down duvets, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (440) "Well maintained property. We’ll stop again should we need to." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet DeJean £82 includes taxes & fees 28 Nov - 29 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/501c540f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/825a993b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/6099e00f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free on-the-go breakfast ](https://images.trvl-media.com/lodging/17000000/16090000/16087600/16087543/f23217d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn Marston 6.0/10 (116) "Had a great time loved it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shyianne [](https://www.expedia.co.uk/Hayti-Hotels-Travel-Inn.h16087543.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/917691e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston Sikeston 8.8/10 Excellent (6) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott £105 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/131ce4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/392abeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite Sikeston 6.8/10 (117) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £49 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5641af73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/d534aac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking | 1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/664c9838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 Sikeston 8.4/10 Very good (277) "Room was clean, breakfast was very good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connie £73 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1906x0y7-e5745fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/51b0d3d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Bathroom | Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/c623404d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/68a43d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Malden Airport Inn Malden 7.0/10 Good (63) "The staff was very nice and professional. The room was very clean. It's just what the doctor ordered at midnight on a drive up from Louisiana." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Everette £37 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1080h1439x0y1-2bafdfca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1050h1619x0y1-13beb152.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/w1060h720x0y199-6f809fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120470000/120467300/120467279/44b354ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room! New Madrid 10/10 Exceptional (1) "The host was very quick to respond and so great to work with for on our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica S. £232 includes taxes & fees 28 Nov - 29 Nov [](https://www.expedia.co.uk/New-Madrid-Hotels-Spacious-3-Bedroom-2-Story-House-In-New-Madrid-Near-Boat-Ramp-With-A-Toy-Room.h120467279.Hotel-Information) ![Fridge, microwave, oven, blender](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/c7fd89d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/ee2b7138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, blender](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/6045fc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/f956f55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern and Cozy Apartment with large windows and sunlight. Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) ![Handicap Room | Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/755237c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/45782657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/60633b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Handicap Room | Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/6128b6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reelfoot Lake Inn Tiptonville 7.2/10 Good (457) "Nice and quiet but there were bugs in the room the fridge didn't keep things cold and the A/C didn't keep the room cool. Great place if you're a fisherman." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla £51 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/96df576d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/fb4c142e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/3c043a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89880000/89872800/89872735/48099d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Great location just across the street from Reelfoot Lake close to boat ramps Hornbeak 9.8/10 Exceptional (74) "The stay was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George H. £140 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Hornbeak-Hotels-Great-Location-Just-Across-The-Street-From-Reelfoot-Lake-Close-To-Boat-Ramps.h89872735.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-08&endDate=2025-12-09®ionId=553248635976433157&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_BF_PROMO_553248635976433157) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations) ## Top New Madrid County Hotel Reviews ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Modern up to date facilities " [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![The Farmstead Hotel](https://images.trvl-media.com/lodging/90000000/89310000/89303500/89303450/26d97631_y.jpg) ### The Farmstead Hotel 10/10 Excellent "No issues" [](https://expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Great staff. Great prices. Beautiful specious rooms. Great all round loved it" [](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Drury Inn & Suites Hayti Caruthersville](https://images.trvl-media.com/lodging/1000000/50000/42200/42109/ff3e4031_y.jpg) ### Drury Inn & Suites Hayti Caruthersville 10/10 Excellent "Good choice for the area. Staff was very friendly and helpful. Breakfast was above expectations. Room was very clean and comfortable. " [](https://expedia.co.uk/Hayti-Hotels-Drury-Inn-Suites-Hayti-Caruthersville.h42109.Hotel-Information) ![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Very nice" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Staff are wonderful, kind and welcoming! The happy hour is a great way to get out of your room and socialize. Lots of yummy food and drinks. " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg) ### Fairfield Inn & Suites by Marriott Sikeston 10/10 Excellent "Extremely clean, and it looks to be updated in the more recent years. Large workout room that looks into the pool. Hot and tasty breakfast. " [](https://expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Century Casino & Hotel Caruthersville](https://images.trvl-media.com/lodging/112000000/111410000/111402100/111402094/690c1aa2_y.jpg) ### Century Casino & Hotel Caruthersville 10/10 Excellent "Room was clean staff was really nice" [](https://expedia.co.uk/Caruthersville-Hotels-Century-Casino-Hotel-Caruthersville.h111402094.Hotel-Information) ![Hampton Inn By Hilton Dexter](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2_y.jpg) ### Hampton Inn By Hilton Dexter 10/10 Excellent "Staff was helpful and professional. The rooms were clean and comfortable " [](https://expedia.co.uk/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in New Madrid County - [Marston Hotels](https://expedia.co.uk/Marston-Hotels.d55824.Travel-Guide-Hotels) - [New Madrid Hotels](https://expedia.co.uk/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels) - [Matthews Hotels](https://expedia.co.uk/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Lilbourn Hotels](https://expedia.co.uk/Lilbourn-Hotels.d553248634983590625.Travel-Guide-Hotels) - [Morehouse Hotels](https://expedia.co.uk/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [Howardville Hotels](https://expedia.co.uk/Howardville-Hotels.d553248634983363505.Travel-Guide-Hotels) - [Gideon Hotels](https://expedia.co.uk/Gideon-Hotels.d3000349377.Travel-Guide-Hotels) - [Risco Hotels](https://expedia.co.uk/Risco-Hotels.d3000349516.Travel-Guide-Hotels) - [Tallapoosa Hotels](https://expedia.co.uk/Tallapoosa-Hotels.d553248634983263480.Travel-Guide-Hotels) - [Canalou Hotels](https://expedia.co.uk/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Mississippi River](https://expedia.co.uk/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Century Casino Caruthersville](https://expedia.co.uk/Century-Casino-Caruthersville-Hotels.0-l553248621532655201-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Hampton Inn Sikeston](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) - [Fairfield Inn & Suites by Marriott Sikeston](https://expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) - [New Orleans Inn Portageville](https://expedia.co.uk/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) - [Super 8 By Wyndham Marston](https://expedia.co.uk/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) - [TownePlace Suites by Marriott Sikeston](https://expedia.co.uk/Sikeston-Hotels-Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) - [The Farmstead Hotel](https://expedia.co.uk/Caruthersville-Hotels-The-Farmstead.h89303450.Hotel-Information) - [Days Inn and Suites by Wyndham Sikeston](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) - [Drury Inn & Suites Sikeston, MO](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) [See a list of all hotels in New Madrid County](https://expedia.co.uk/All-New-Madrid-County-Hotels.d553248635976433157.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in New Madrid County on Expedia.com](https://www.expedia.com/Destinations-In-New-Madrid-County.d553248635976433157.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Thorps Farm Bed and Breakfast](https://expedia.co.uk/Fordingbridge-Hotels-Thorps-Farm-Bed-And-Breakfast.h39186499.Hotel-Information) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)