Title: Los Santos Gay-Friendly Hotels, Panama: Los Santos Hotel Guide | Expedia.co.uk

[Los Santos Travel Guide](https://expedia.co.uk/Los-Santos.dx6246240)[Los Santos Hotels](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Hotel-Destinations)[Holiday Rentals in Los Santos](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Holiday-Rental-Destinations)[Los Santos Flights](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Flight-Destinations)[Los Santos Car Hire](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Car-Hire-Destinations)[Los Santos Holidays](https://expedia.co.uk/Los-Santos.d6246240.Holidays-City-Breaks)

![View at Venao beach in Azuero peninsula, Panama.](https://images.trvl-media.com/place/6336814/792c4e82-5e8a-4f1d-b9a6-3ef041d48b83.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Search Gay-Friendly Hotels in Los Santos

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Save instantly and earn perks with One Key  
[Learn about One Key](https://www.expedia.co.uk/welcome-one-key)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check availability on Los Santos Gay-Friendly Hotels

Tonight

[24 Dec - 25 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming)

Tomorrow

[25 Dec - 26 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-12-25&endDate=2025-12-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming)

This weekend

[26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming)

Next weekend

[2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Gay-Friendly-Hotel.0-0-d6246240-tGayFriendlyHotel.Hotel-Filter-Destinations)[

Sign up, it's free

](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Gay-Friendly-Hotel.0-0-d6246240-tGayFriendlyHotel.Hotel-Filter-Destinations)

## Top Los Santos Hotel Reviews

![Villa Marina Lodge & Condos](https://images.trvl-media.com/lodging/10000000/9550000/9542300/9542280/8ba948e1_y.jpg)

### Villa Marina Lodge & Condos

10/10 Excellent

"Had a wonderful experience staying at Villa Marina Lodge. The Condo was in very good conditions and was very comfortable. The staff was always helpful and check-in was easy and smooth. The location is perfect with sights to the beach and just a few minutes walking from Playa Venao but still far enough to keep a quiet and relaxing environment in the area. Everything was good, I'd love to comeback! "

[](https://expedia.co.uk/Las-Escobas-Del-Venado-Hotels-Villa-Marina-Lodge-Condos.h9542280.Hotel-Information)

![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg)

### Hotel Riu Playa Blanca - All Inclusive

10/10 Excellent

"The property was great, food options were plentiful, but the staff made it memorable! From Maricruz bringing such joy to every meal we were lucky enough to see her, to Alex and Yunier behind the bar making tasty drinks quickly, to Abdiel ensuring the pool was safe and enjoyable, to Eleuterio helping us find a lost personal item and being so nice! For anyone traveling without children, the pool with the swim up bar is adults only and consistently enforced - we only really saw kiddos at meals. Overall would recommend!"

[](https://expedia.co.uk/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information)

![Hotel Cubitá Boutique Resort & Spa](https://images.trvl-media.com/lodging/10000000/9680000/9675400/9675316/9ea589c5_y.jpg)

### Hotel Cubitá Boutique Resort & Spa

10/10 Excellent

"Really nice hotel staff is wonderful "

[](https://expedia.co.uk/La-Arena-Hotels-Hotel-Cubita.h9675316.Hotel-Information)

![Hotel Faranda Guayacanes, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/980000/971000/970914/2fd85024_y.jpg)

### Hotel Faranda Guayacanes, a member of Radisson Individuals

10/10 Excellent

"The room was spotless and the staff were wonderful. I will stay at the hotel again. "

[](https://expedia.co.uk/Chitre-Hotels-Hotel-Faranda-Guayacanes.h970914.Hotel-Information)

![The Buenaventura Golf & Beach Resort Panama, Autograph Collection](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/11d8f39d_y.jpg)

### The Buenaventura Golf & Beach Resort Panama, Autograph Collection

10/10 Excellent

"Beautiful resort"

[](https://expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information)

![Hotel Presidente](https://images.trvl-media.com/lodging/16000000/15620000/15615000/15614946/8b2929d2_y.jpg)

### Hotel Presidente

10/10 Excellent

"Yes"

[](https://expedia.co.uk/Las-Tablas-Hotels-Hotel-Presidente.h15614946.Hotel-Information)

![ Grand Decameron Panama, A Trademark All Inclusive Resort](https://images.trvl-media.com/lodging/1000000/980000/976000/975964/0a66855c_y.jpg)

###  Grand Decameron Panama, A Trademark All Inclusive Resort

10/10 Excellent

"Beautiful resort "

[](https://expedia.co.uk/Rio-Hato-Hotels-Royal-Decameron-Panama-All-Inclusive.h975964.Hotel-Information)

![Playa Blanca Beach Resort - All Inclusive](https://images.trvl-media.com/lodging/1000000/970000/967200/967117/09199a01_y.jpg)

### Playa Blanca Beach Resort - All Inclusive

10/10 Excellent

"Safe áreas , excelente customer services,recreation team super good ,the común áreas and pools needs paint "

[](https://expedia.co.uk/Rio-Hato-Hotels-Playa-Blanca-Beach-Resort-All-Inclusive.h967117.Hotel-Information)

![Sansara Surf and Yoga Resort - Retreat](https://images.trvl-media.com/lodging/20000000/19240000/19231100/19231080/cacb680b_y.jpg)

### Sansara Surf and Yoga Resort - Retreat

10/10 Excellent

"Amazing stay in a amazing location friendly staff and great facilities restaurant is incredible and yoga options "

[](https://expedia.co.uk/Cambutal-Hotels-Sansara-Surf-And-Yoga-Resort-Retreat.h19231080.Hotel-Information)

## Explore a world of travel with Expedia

- Accommodation
- Flights
- Packages
- Cars

- [4 Star Hotels in La Palma ](https://www.expedia.co.uk/4Star-La-Palma-Hotels.s40-0-d553248634761867191.Travel-Guide-Filter-Hotels)
- [Canas Hotels ](https://www.expedia.co.uk/Canas-Hotels.d553248623859250109.Travel-Guide-Hotels)
- [Guarare Hotels ](https://www.expedia.co.uk/Guarare-Hotels.d3000387438.Travel-Guide-Hotels)
- [Hotels near Iguana Island National Park ](https://www.expedia.co.uk/Iguana-Island-National-Park-Hotels.0-l6286174-0.Travel-Guide-Filter-Hotels)
- [Resorts in Isla Canas ](https://www.expedia.co.uk/Isla-Canas-Hotel-Resorts.d6286066-aaHotelResorts.Travel-Guide-Accommodation)
- [Isla Iguana Hotels ](https://www.expedia.co.uk/Isla-Iguana-Hotels.d553248623461873998.Travel-Guide-Hotels)
- [La Palma Hotels ](https://www.expedia.co.uk/La-Palma-Hotels.d553248634761867191.Travel-Guide-Hotels)
- [La Villa de los Santos Hotels ](https://www.expedia.co.uk/La-Villa-De-Los-Santos-Hotels.d553248623140686317.Travel-Guide-Hotels)
- [Las Escobas del Venado Hotels ](https://www.expedia.co.uk/Las-Escobas-Del-Venado-Hotels.d6336814.Travel-Guide-Hotels)
- [Las Tablas Hotels ](https://www.expedia.co.uk/Las-Tablas-Hotels.d6347532.Travel-Guide-Hotels)
- [Ojo de Agua Hotels ](https://www.expedia.co.uk/Ojo-De-Agua-Hotels.d553248623859250163.Travel-Guide-Hotels)
- [Pedasí Hotels ](https://www.expedia.co.uk/Pedasi-Hotels.d6130073.Travel-Guide-Hotels)
- [Hotels near Playa El Toro ](https://www.expedia.co.uk/Playa-El-Toro-Hotels.0-l6286158-0.Travel-Guide-Filter-Hotels)
- [Santo Domingo Hotels ](https://www.expedia.co.uk/Santo-Domingo-Hotels.d553248623199120260.Travel-Guide-Hotels)

- [Flights to Las Tablas ](https://www.expedia.co.uk/Cheap-Flights-To-Las-Tablas.d6347532.Travel-Guide-Flights)
- [Flights to Pedasí ](https://www.expedia.co.uk/Cheap-Flights-To-Pedasi.d6130073.Travel-Guide-Flights)

- [Visit Guarare ](https://www.expedia.co.uk/Guarare.dx3000387438)
- [Visit Isla Canas ](https://www.expedia.co.uk/Isla-Canas.dx6286066)
- [Isla Iguana Holidays ](https://www.expedia.co.uk/Isla-Iguana.d553248623461873998.Holidays-City-Breaks)
- [Visit Las Escobas del Venado ](https://www.expedia.co.uk/Las-Escobas-Del-Venado.dx6336814)
- [Pedasí Holidays ](https://www.expedia.co.uk/Pedasi.d6130073.Holidays-City-Breaks)
- [Visit Pedasí ](https://www.expedia.co.uk/Pedasi.dx6130073)

- [Avis Rental Cars in Isla Canas ](https://www.expedia.co.uk/Avis-Car-Rentals-In-Isla-Canas.d6286066-c41.Car-Rental-Guide-Suppliers)
- [Thai Cars Rental Cars in Isla Canas ](https://www.expedia.co.uk/Thai-Cars-Car-Rentals-In-Isla-Canas.d6286066-c1027.Car-Rental-Guide-Suppliers)