Title: Los Santos Gay-Friendly Hotels, Panama: Los Santos Hotel Guide | Expedia.co.uk [Los Santos Travel Guide](https://expedia.co.uk/Los-Santos.dx6246240)[Los Santos Hotels](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Hotel-Destinations)[Holiday Rentals in Los Santos](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Holiday-Rental-Destinations)[Los Santos Flights](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Flight-Destinations)[Los Santos Car Hire](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Car-Hire-Destinations)[Los Santos Holidays](https://expedia.co.uk/Los-Santos.d6246240.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/9/06f60e4c93e3996e5ea4a5b09f97584c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Gay-Friendly Hotels in Los Santos ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Los Santos Gay-Friendly Hotels Tonight [23 Sept - 24 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-09-23&endDate=2025-09-24&adults=2&travelerType=LGBT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [24 Sept - 25 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-09-24&endDate=2025-09-25&adults=2&travelerType=LGBT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=LGBT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=LGBT&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Los Santos Gay-Friendly Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Gay-Friendly-Hotel.0-0-d6246240-tGayFriendlyHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Gay-Friendly-Hotel.0-0-d6246240-tGayFriendlyHotel.Hotel-Filter-Destinations) ## Top Los Santos Hotel Reviews ![Hotel Posada Destiladeros](//images.trvl-media.com/lodging/12000000/11840000/11838000/11837980/0e32d678_y.jpg) ### Hotel Posada Destiladeros 10/10 Excellent "The sea view was amazing and it had easy access to the beach. The breakfast was lovely. The hosts are very helpful. The restaurant evening meal was wonderful, we had fresh fish and shrimp. A good selection of drinks was also available. A short drive from Pedasi. We also saw a yellow caracara at breakfast as well as a black vulture." [](https://expedia.co.uk/Punta-Mala-Hotels-Hotel-Posada-Destiladeros.h11837980.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](//images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg) ### Hotel Riu Playa Blanca - All Inclusive 10/10 Excellent "one of the cleanest hotels i ever stayed at. Food was very good and different variety every night with lots of salads and fruit in addition to fish and meats and sushi bar. Ocean front view and steps awway from hotel. Would definitely go back. " [](https://expedia.co.uk/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) ![The Buenaventura Golf & Beach Resort Panama, Autograph Collection](//images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/11d8f39d_y.jpg) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection 10/10 Excellent "Spectacular hotel right in front of the beach. Extremely friendly staff. Plenty of restaurant options with top notch food. I definitely recommend it!" [](https://expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Hotel Cubitá Boutique Resort & Spa](//images.trvl-media.com/lodging/10000000/9680000/9675400/9675316/9ea589c5_y.jpg) ### Hotel Cubitá Boutique Resort & Spa 10/10 Excellent "Staff was lovely. Will be back soon. " [](https://expedia.co.uk/La-Arena-Hotels-Hotel-Cubita.h9675316.Hotel-Information) ![Hotel Punta Franca](//images.trvl-media.com/lodging/12000000/11300000/11295600/11295531/w750h558x0y0-43779190_y.jpg) ### Hotel Punta Franca 10/10 Excellent "The place is on top of a hill which gives you an spectacular ocean view. In the morning you can hear birds and the amazing sound of the ocean waves below. It is a place to enjoy nature, views, tranquility, the beach, sand, just to breathe fresh air. It’s a quiet atmosphere, not a party place. I love this quietness and I will come back soon. The staff is super friendly and welcoming. There is no refrigerator in the room, so i guess we better bring a cooler with ice next time. It’s really an amazing experience in Playa Destiladeros, Pedasi " [](https://expedia.co.uk/Punta-Mala-Hotels-Hotel-Punta-Franca.h11295531.Hotel-Information) ![ Grand Decameron Panama, A Trademark All Inclusive Resort](//images.trvl-media.com/lodging/1000000/980000/976000/975964/0a66855c_y.jpg) ### Grand Decameron Panama, A Trademark All Inclusive Resort 10/10 Excellent "The best option for family trip." [](https://expedia.co.uk/Rio-Hato-Hotels-Royal-Decameron-Panama-All-Inclusive.h975964.Hotel-Information) ![Playa Blanca Beach Resort - All Inclusive](//images.trvl-media.com/lodging/1000000/970000/967200/967117/39c2572a_y.jpg) ### Playa Blanca Beach Resort - All Inclusive 8/10 Good "Food at the buffet was good, a variety for every taste and preferences. Restaurants reservations were not that bad and there's alway the choice of complementing with the buffet if La Carta is not as expected. The bed was comfortable and clean." [](https://expedia.co.uk/Rio-Hato-Hotels-Playa-Blanca-Beach-Resort-All-Inclusive.h967117.Hotel-Information) ![Hotel Faranda Guayacanes, a member of Radisson Individuals](//images.trvl-media.com/lodging/1000000/980000/971000/970914/2fd85024_y.jpg) ### Hotel Faranda Guayacanes, a member of Radisson Individuals 10/10 Excellent "Beautiful grounds, friendly staff, very good restaurant " [](https://expedia.co.uk/Chitre-Hotels-Hotel-Faranda-Guayacanes.h970914.Hotel-Information) ![Apartamento en Playa Blanca Town Center](//images.trvl-media.com/lodging/28000000/27930000/27920100/27920007/w825h460x7y0-26330902_y.jpg) ### Apartamento en Playa Blanca Town Center 8/10 Good "Quite remote complex with an interesting pool concept. Come with your own groceries. Well appointed condo! " [](https://expedia.co.uk/Rio-Hato-Hotels-Apartamento-En-Playa-Blanca-Town-Center.h27920007.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - [4 Star Hotels in La Palma](https://www.expedia.co.uk/4Star-La-Palma-Hotels.s40-0-d553248634761867191.Travel-Guide-Filter-Hotels) - [Canas Hotels](https://www.expedia.co.uk/Canas-Hotels.d553248623859250109.Travel-Guide-Hotels) - [Guarare Hotels](https://www.expedia.co.uk/Guarare-Hotels.d3000387438.Travel-Guide-Hotels) - [Hotels near Iguana Island National Park](https://www.expedia.co.uk/Iguana-Island-National-Park-Hotels.0-l6286174-0.Travel-Guide-Filter-Hotels) - [Resorts in Isla Canas](https://www.expedia.co.uk/Isla-Canas-Hotel-Resorts.d6286066-aaHotelResorts.Travel-Guide-Accommodation) - [Isla Iguana Hotels](https://www.expedia.co.uk/Isla-Iguana-Hotels.d553248623461873998.Travel-Guide-Hotels) - [La Palma Hotels](https://www.expedia.co.uk/La-Palma-Hotels.d553248634761867191.Travel-Guide-Hotels) - [La Villa de los Santos Hotels](https://www.expedia.co.uk/La-Villa-De-Los-Santos-Hotels.d553248623140686317.Travel-Guide-Hotels) - [Las Escobas del Venado Hotels](https://www.expedia.co.uk/Las-Escobas-Del-Venado-Hotels.d6336814.Travel-Guide-Hotels) - [Las Tablas Hotels](https://www.expedia.co.uk/Las-Tablas-Hotels.d6347532.Travel-Guide-Hotels) - [Ojo de Agua Hotels](https://www.expedia.co.uk/Ojo-De-Agua-Hotels.d553248623859250163.Travel-Guide-Hotels) - [Pedasí Hotels](https://www.expedia.co.uk/Pedasi-Hotels.d6130073.Travel-Guide-Hotels) - [Hotels near Playa El Toro](https://www.expedia.co.uk/Playa-El-Toro-Hotels.0-l6286158-0.Travel-Guide-Filter-Hotels) - [Santo Domingo Hotels](https://www.expedia.co.uk/Santo-Domingo-Hotels.d553248623199120260.Travel-Guide-Hotels) - [Flights to Las Tablas](https://www.expedia.co.uk/Cheap-Flights-To-Las-Tablas.d6347532.Travel-Guide-Flights) - [Flights to Pedasí](https://www.expedia.co.uk/Cheap-Flights-To-Pedasi.d6130073.Travel-Guide-Flights) - [Visit Guarare](https://www.expedia.co.uk/Guarare.dx3000387438) - [Visit Isla Canas](https://www.expedia.co.uk/Isla-Canas.dx6286066) - [Isla Iguana Holidays](https://www.expedia.co.uk/Isla-Iguana.d553248623461873998.Holidays-City-Breaks) - [Visit Las Escobas del Venado](https://www.expedia.co.uk/Las-Escobas-Del-Venado.dx6336814) - [Pedasí Holidays](https://www.expedia.co.uk/Pedasi.d6130073.Holidays-City-Breaks) - [Visit Pedasí](https://www.expedia.co.uk/Pedasi.dx6130073) - [Avis Rental Cars in Isla Canas](https://www.expedia.co.uk/Avis-Car-Rentals-In-Isla-Canas.d6286066-c41.Car-Rental-Guide-Suppliers) - [Thai Cars Rental Cars in Isla Canas](https://www.expedia.co.uk/Thai-Cars-Car-Rentals-In-Isla-Canas.d6286066-c1027.Car-Rental-Guide-Suppliers)