Title: Los Santos Gay-Friendly Hotels, Panama: Los Santos Hotel Guide | Expedia.co.uk [Los Santos Travel Guide](https://expedia.co.uk/Los-Santos.dx6246240)[Los Santos Hotels](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Hotel-Destinations)[Holiday Rentals in Los Santos](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Holiday-Rental-Destinations)[Los Santos Flights](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Flight-Destinations)[Los Santos Car Hire](https://expedia.co.uk/Destinations-In-Los-Santos.d6246240.Car-Hire-Destinations)[Los Santos Holidays](https://expedia.co.uk/Los-Santos.d6246240.Holidays-City-Breaks) ![View at Venao beach in Azuero peninsula, Panama.](https://images.trvl-media.com/place/6336814/792c4e82-5e8a-4f1d-b9a6-3ef041d48b83.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Gay-Friendly Hotels in Los Santos - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Los Santos Gay-Friendly Hotels Tonight [8 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-11-08&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Tomorrow [9 Nov - 10 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-11-09&endDate=2025-11-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) In two weeks [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6246240&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) ## Top Los Santos Gay-Friendly Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Gay-Friendly-Hotel.0-0-d6246240-tGayFriendlyHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-Gay-Friendly-Hotel.0-0-d6246240-tGayFriendlyHotel.Hotel-Filter-Destinations) ## Top Los Santos Hotel Reviews ![Villa Marina Lodge & Condos](//images.trvl-media.com/lodging/10000000/9550000/9542300/9542280/8ba948e1_y.jpg) ### Villa Marina Lodge & Condos 10/10 Excellent "Great" [](https://expedia.co.uk/Las-Escobas-Del-Venado-Hotels-Villa-Marina-Lodge-Condos.h9542280.Hotel-Information) ![The Buenaventura Golf & Beach Resort Panama, Autograph Collection](//images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/11d8f39d_y.jpg) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection 10/10 Excellent "Always a fantastic experience across the board! Love staying here!" [](https://expedia.co.uk/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](//images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg) ### Hotel Riu Playa Blanca - All Inclusive 10/10 Excellent "We had an awesome time at this RIU. The grounds were amazingly well kept, the food was mostly delicious, the beach was great. Near the end of our vacation, we were looking for things to complain about. And when you have to think that hard about it, l would say that you’ve had a wonderful time. I think housekeeping was one area that they could work on. We placed the…no service sign on our door. They still came in our room and removed all of the towels without replacing them. In room coffee packets weren’t replenished. So, the big question … would we return ? Most definitely YES. We’ll probably be back next year and bring our kids. " [](https://expedia.co.uk/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) ![Playa Blanca Beach Resort - All Inclusive](//images.trvl-media.com/lodging/1000000/970000/967200/967117/09199a01_y.jpg) ### Playa Blanca Beach Resort - All Inclusive 10/10 Excellent "Safe áreas , excelente customer services,recreation team super good ,the común áreas and pools needs paint " [](https://expedia.co.uk/Rio-Hato-Hotels-Playa-Blanca-Beach-Resort-All-Inclusive.h967117.Hotel-Information) ![Hotel Posada Destiladeros](//images.trvl-media.com/lodging/12000000/11840000/11838000/11837980/8cc9da2c_y.jpg) ### Hotel Posada Destiladeros 10/10 Excellent "The sea view was amazing and it had easy access to the beach. The breakfast was lovely. The hosts are very helpful. The restaurant evening meal was wonderful, we had fresh fish and shrimp. A good selection of drinks was also available. A short drive from Pedasi. We also saw a yellow caracara at breakfast as well as a black vulture." [](https://expedia.co.uk/Punta-Mala-Hotels-Hotel-Posada-Destiladeros.h11837980.Hotel-Information) ![Hotel Cubitá Boutique Resort & Spa](//images.trvl-media.com/lodging/10000000/9680000/9675400/9675316/9ea589c5_y.jpg) ### Hotel Cubitá Boutique Resort & Spa 10/10 Excellent "Staff was lovely. Will be back soon. " [](https://expedia.co.uk/La-Arena-Hotels-Hotel-Cubita.h9675316.Hotel-Information) ![ Grand Decameron Panama, A Trademark All Inclusive Resort](//images.trvl-media.com/lodging/1000000/980000/976000/975964/0a66855c_y.jpg) ### Grand Decameron Panama, A Trademark All Inclusive Resort 10/10 Excellent "The best option for family trip." [](https://expedia.co.uk/Rio-Hato-Hotels-Royal-Decameron-Panama-All-Inclusive.h975964.Hotel-Information) ![Hotel Faranda Guayacanes, a member of Radisson Individuals](//images.trvl-media.com/lodging/1000000/980000/971000/970914/2fd85024_y.jpg) ### Hotel Faranda Guayacanes, a member of Radisson Individuals 10/10 Excellent "Beautiful grounds, friendly staff, very good restaurant " [](https://expedia.co.uk/Chitre-Hotels-Hotel-Faranda-Guayacanes.h970914.Hotel-Information) ![Apartamento en Playa Blanca Town Center](//images.trvl-media.com/lodging/28000000/27930000/27920100/27920007/w825h460x7y0-26330902_y.jpg) ### Apartamento en Playa Blanca Town Center 8/10 Good "Quite remote complex with an interesting pool concept. Come with your own groceries. Well appointed condo! " [](https://expedia.co.uk/Rio-Hato-Hotels-Apartamento-En-Playa-Blanca-Town-Center.h27920007.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - [4 Star Hotels in La Palma](https://www.expedia.co.uk/4Star-La-Palma-Hotels.s40-0-d553248634761867191.Travel-Guide-Filter-Hotels) - [Canas Hotels](https://www.expedia.co.uk/Canas-Hotels.d553248623859250109.Travel-Guide-Hotels) - [Guarare Hotels](https://www.expedia.co.uk/Guarare-Hotels.d3000387438.Travel-Guide-Hotels) - [Hotels near Iguana Island National Park](https://www.expedia.co.uk/Iguana-Island-National-Park-Hotels.0-l6286174-0.Travel-Guide-Filter-Hotels) - [Resorts in Isla Canas](https://www.expedia.co.uk/Isla-Canas-Hotel-Resorts.d6286066-aaHotelResorts.Travel-Guide-Accommodation) - [Isla Iguana Hotels](https://www.expedia.co.uk/Isla-Iguana-Hotels.d553248623461873998.Travel-Guide-Hotels) - [La Palma Hotels](https://www.expedia.co.uk/La-Palma-Hotels.d553248634761867191.Travel-Guide-Hotels) - [La Villa de los Santos Hotels](https://www.expedia.co.uk/La-Villa-De-Los-Santos-Hotels.d553248623140686317.Travel-Guide-Hotels) - [Las Escobas del Venado Hotels](https://www.expedia.co.uk/Las-Escobas-Del-Venado-Hotels.d6336814.Travel-Guide-Hotels) - [Las Tablas Hotels](https://www.expedia.co.uk/Las-Tablas-Hotels.d6347532.Travel-Guide-Hotels) - [Ojo de Agua Hotels](https://www.expedia.co.uk/Ojo-De-Agua-Hotels.d553248623859250163.Travel-Guide-Hotels) - [Pedasí Hotels](https://www.expedia.co.uk/Pedasi-Hotels.d6130073.Travel-Guide-Hotels) - [Hotels near Playa El Toro](https://www.expedia.co.uk/Playa-El-Toro-Hotels.0-l6286158-0.Travel-Guide-Filter-Hotels) - [Santo Domingo Hotels](https://www.expedia.co.uk/Santo-Domingo-Hotels.d553248623199120260.Travel-Guide-Hotels) - [Flights to Las Tablas](https://www.expedia.co.uk/Cheap-Flights-To-Las-Tablas.d6347532.Travel-Guide-Flights) - [Flights to Pedasí](https://www.expedia.co.uk/Cheap-Flights-To-Pedasi.d6130073.Travel-Guide-Flights) - [Visit Guarare](https://www.expedia.co.uk/Guarare.dx3000387438) - [Visit Isla Canas](https://www.expedia.co.uk/Isla-Canas.dx6286066) - [Isla Iguana Holidays](https://www.expedia.co.uk/Isla-Iguana.d553248623461873998.Holidays-City-Breaks) - [Visit Las Escobas del Venado](https://www.expedia.co.uk/Las-Escobas-Del-Venado.dx6336814) - [Pedasí Holidays](https://www.expedia.co.uk/Pedasi.d6130073.Holidays-City-Breaks) - [Visit Pedasí](https://www.expedia.co.uk/Pedasi.dx6130073) - [Avis Rental Cars in Isla Canas](https://www.expedia.co.uk/Avis-Car-Rentals-In-Isla-Canas.d6286066-c41.Car-Rental-Guide-Suppliers) - [Thai Cars Rental Cars in Isla Canas](https://www.expedia.co.uk/Thai-Cars-Car-Rentals-In-Isla-Canas.d6286066-c1027.Car-Rental-Guide-Suppliers)