A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Check prices for these dates

In two weeks
30 Oct - 1 Nov
In two months
11 Dec - 13 Dec
In three months
8 Jan - 10 Jan
In four months
5 Feb - 7 Feb

Our top choices for Defiance apartments

A hotel pool area with a rectangular pool, lounge chairs, and a wooden bench.

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
4.0 out of 10, (1 review)
"Property was dirty, kitchen hadn’t been cleaned. Microwave had food spilled all over inside. Place felt grimy."
United States
Jenny D.
The price is £122
includes taxes & fees
20 Oct - 21 Oct
Great for Business Travelers! Pool + Gym
A room with a dark wooden wall, a brown leather sofa, a white door, and a patterned wall.

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is £205
includes taxes & fees
15 Oct - 16 Oct
Stylish1BRStudioCleanQuietandCozy
A two-story building with a balcony, a staircase, and a gated entrance.

3. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (11 reviews)
"The property was clean and comfortable and everything you may need is there, walking distance was very close to everything in the area. Communication with the host was easy and quick responses, overall it was a great place to stay!"
United States
Melinda
The price is £143
includes taxes & fees
18 Oct - 19 Oct
2nd Street -Deck Suite (back entrance)
A bedroom with a bed, a dresser, a mirror, a ceiling fan, and a door leading to another room.

4. Enjoyable 2-bedroom apartment at St. Peters; Near STL

Enjoyable 2-bedroom apartment at St. Peters; Near STL
St. Peters
The price is £212
includes taxes & fees
19 Oct - 20 Oct
Enjoyable 2-bedroom apartment at St. Peters; Near STL
A set of stone steps leading to a garage with a car parked inside.

5. Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
Ballwin
7.8 out of 10, Good, (24 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is £114
includes taxes & fees
20 Oct - 21 Oct
Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
A front door with a sign for '2nd St Loft' and a 'Self Check In' option.

6. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (19 reviews)
"Everything was great room was very clean"
United States
Chance W.
The price is £135
includes taxes & fees
26 Oct - 27 Oct
2nd Street Loft - Riverview
A spacious living room with hardwood floors, a white armchair, a sofa, and a TV on a stand.

7. The Cul-de-Sac Retreat

The Cul-de-Sac Retreat
Saint Charles
7.6 out of 10, Good, (10 reviews)
"Great house, great location - close to the St. Charles convention center"
United States
Joe H.
The price is £223
includes taxes & fees
14 Oct - 15 Oct
The Cul-de-Sac Retreat
Living area

8. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (3 reviews)
"Great location. Host quick to reply to questions!! Would stay here again."
United States
Dilauna B.
The price is £358
includes taxes & fees
19 Oct - 20 Oct
Family Friendly w/ Game Room in Quiet Neighborhood
A living room with a white sofa, two armchairs, a wooden coffee table, and a side table with a plant.

9. The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.4 out of 10, Very good, (5 reviews)
"This was the perfect place for my friends and I to stay in Marthasville. Lots of space and amenities. We did not use the complimentary breakfast, but is a great addition. Would recommend to anyone staying in the area. "
United States
Adam K.
The price is £352
includes taxes & fees
15 Oct - 16 Oct
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
A modern kitchen with white cabinets, a black refrigerator, a stainless steel microwave, and a black oven. There are four blue bowls on a wooden table with a woven placemat.

10. Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
Moscow Mills
10.0 out of 10, Exceptional, (14 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is £204
includes taxes & fees
18 Oct - 19 Oct
Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
A hotel room with a bed, a desk, a chair, a lamp, and a telephone.

11. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.6 out of 10, Exceptional, (42 reviews)
"Great spot!"
United States
Anonymous traveller
The price is £50
includes taxes & fees
11 Nov - 12 Nov
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
A neatly made bed with a stack of folded towels, a bedside lamp, and a ceiling fan in a room with a large window and a wall-mounted artwork.

12. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (12 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is £205
includes taxes & fees
18 Oct - 19 Oct
Walk to Main | Pet-Friendly Yard & Workspace
A modern kitchen with stainless steel appliances, white cabinetry, and a brick accent wall.

13. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is £247
includes taxes & fees
15 Oct - 16 Oct
Historic Main St. Customs House Upstairs Apartment
A modern kitchen with white cabinets, a built-in microwave, a stove, and a window providing natural light.

14. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (26 reviews)
"Great location"
United States
todd p.
The price is £211
includes taxes & fees
18 Oct - 19 Oct
Pet-Friendly Duplex | Historic Main
Free breakfast available on-site.

15. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
The price is £187
includes taxes & fees
8 Nov - 9 Nov
Studio | Lovely Suite Close to Edward Jones!
A brick building with numbered doors, a covered walkway, and a visible handicap accessibility sign.

16. Foundry Flat | Main Street & Free Parking

Foundry Flat | Main Street & Free Parking
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"Everything was exactly as described. St. Charles is an awesome place!"
United States
Michael
The price is £232
includes taxes & fees
15 Oct - 16 Oct
Foundry Flat | Main Street & Free Parking
A hallway with a door, two potted plants, a doormat, and a view of a brick building through large windows.

17. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is £210
includes taxes & fees
21 Oct - 22 Oct
Dog-Friendly 2BR | Walk to Main Street
A staircase with white railings and a ceiling fan.

18. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (69 reviews)
"This was a prime spot for downtown activities! Near everything and not far from STL. Would absolutely stay here again!"
United States
Rebecca F.
The price is £187
includes taxes & fees
14 Oct - 15 Oct
Amazing Renovated Historic Loft on Main Street
A spacious living area with a wooden floor, a dining table with chairs, a flat-screen TV mounted on the wall, and a kitchen area with modern appliances.

19. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (194 reviews)
"Such an awesome place! Super. Lean and great location. Loved our stay!"
United States
Jill C.
The price is £187
includes taxes & fees
14 Oct - 15 Oct
The Lofts of North Main Street
A row of multi-story buildings with commercial storefronts, including a cafe and a restaurant.

20. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (40 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is £155
includes taxes & fees
20 Oct - 21 Oct
Historic Main Street Studio | Dog-Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

8/10 Good
"Nice hotel, but not up to usual standards! Two long black hairs on the wall of the shower! Never makes you feel good!"
Teresa 1-night trip
Posted 3 hours ago
Drury Inn & Suites Southwest St. Louis

Find out more about Defiance

Defiance Apartments information

Number of reviews
513
Accommodation
111 Apartments
Lowest Price
£50
Highest Price
£358

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights , 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and a Smart TV . 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights . Free WiFi and a Smart TV are included . The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km away. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Driftwood Den | Boho 2BR | Dog-Friendly: It's located in St. Charles , 19 mi/30.6 km from Defiance. Includes free WiFi .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.