A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Check prices for these dates

In two weeks
11 Sept - 13 Sept
In two months
23 Oct - 25 Oct
In three months
20 Nov - 22 Nov
In four months
18 Dec - 20 Dec

Our top choices for Defiance apartments

Interior

1. 2 Queen Beds | Mobil Access Tub Nsmk Kitchen

2 Queen Beds | Mobil Access Tub Nsmk Kitchen
Westport
9.8 out of 10, Exceptional, (45 reviews)
"Great place to stay!"
United States
Anonymous traveller
The price is £58
includes taxes & fees
7 Sept - 8 Sept
2 Queen Beds | Mobil Access Tub Nsmk Kitchen
Interior

2. Family Home: Game Room & Huge Yard, Airport

Family Home: Game Room & Huge Yard, Airport
Maryland Heights
10.0 out of 10, Exceptional, (1 review)
"Very nice"
United States
Steven S.
The price is £331
includes taxes & fees
6 Sept - 7 Sept
Family Home: Game Room & Huge Yard, Airport
Private kitchen

3. Quiet Neighborhood-Near Eats & Shops-Airport!

Quiet Neighborhood-Near Eats & Shops-Airport!
Brookside
10.0 out of 10, Exceptional, (2 reviews)
"This was an awesome place for 9 of us- plenty of rooms to sleep and bathrooms. The renter was very kind"
United States
Janet
The price is £345
includes taxes & fees
27 Aug - 28 Aug
Quiet Neighborhood-Near Eats & Shops-Airport!
Exterior

4. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is £155
includes taxes & fees
30 Aug - 31 Aug
Historic Main Street Studio | Dog-Friendly
Interior

5. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (38 reviews)
"Fantastic place!"
United States
Anonymous traveller
The price is £51
includes taxes & fees
30 Aug - 31 Aug
2 Queen Beds | Non-Smoking, Kitchen
Interior

6. 3BR Family+Game Retreat 8 min STL Airport/Westport

3BR Family+Game Retreat 8 min STL Airport/Westport
Maryland Heights
8.8 out of 10, Excellent, (11 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
The price is £314
includes taxes & fees
27 Aug - 28 Aug
3BR Family+Game Retreat 8 min STL Airport/Westport
Interior

7. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is £193
includes taxes & fees
27 Aug - 28 Aug
Amazing Renovated Historic Loft on Main Street
Room

8. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.6 out of 10, Exceptional, (41 reviews)
"Great spot!"
United States
Anonymous traveller
The price is £52
includes taxes & fees
30 Aug - 31 Aug
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Dining

9. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
The price is £167
includes taxes & fees
30 Aug - 31 Aug
Studio | Lovely Suite Close to Edward Jones!
Living area

10. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (116 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is £193
includes taxes & fees
27 Aug - 28 Aug
Prime Loft of Main Street
Property grounds

11. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Ballwin
7.8 out of 10, Good, (23 reviews)
"Nice and roomy place! The shower was a little messy when we went but everything else wemt well"
United States
alex h.
The price is £111
includes taxes & fees
6 Sept - 7 Sept
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Living area

12. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (41 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
The price is £279
includes taxes & fees
30 Aug - 31 Aug
Historic Main St 2BR | Steps to Shops
Interior

13. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (187 reviews)
"It was great! Clean and great communication with host."
United States
Natalie H.
The price is £194
includes taxes & fees
30 Aug - 31 Aug
The Lofts of North Main Street
Private kitchen

14. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
The price is £189
includes taxes & fees
2 Sept - 3 Sept
Pet-Friendly Duplex | Historic Main
Property grounds

15. Driftwood Den | Boho 2BR | Dog-Friendly

Driftwood Den | Boho 2BR | Dog-Friendly
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
The price is £222
includes taxes & fees
30 Aug - 31 Aug
Driftwood Den | Boho 2BR | Dog-Friendly
Interior

16. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is £207
includes taxes & fees
2 Sept - 3 Sept
Dog-Friendly 2BR | Walk to Main Street
Living area

17. Historic Main St 1BR | Walk to Dining & Nightlife

Historic Main St 1BR | Walk to Dining & Nightlife
St. Charles Historic District
9.0 out of 10, Wonderful, (22 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
The price is £198
includes taxes & fees
30 Aug - 31 Aug
Historic Main St 1BR | Walk to Dining & Nightlife
Exterior

18. The Oak & Aura Retreat

The Oak & Aura Retreat
St. Charles Historic District
8.0 out of 10, Very good, (2 reviews)
"Great location, and very clean! Would stay here again!"
United States
Rachel B.
The price is £222
includes taxes & fees
30 Aug - 31 Aug
The Oak & Aura Retreat
Room

19. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
9.8 out of 10, Exceptional, (9 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is £212
includes taxes & fees
31 Aug - 1 Sept
Walk to Main | Pet-Friendly Yard & Workspace
Living area

20. Main Street 2BR Apartment with Garage and Deck

Main Street 2BR Apartment with Garage and Deck
St. Charles Historic District
9.4 out of 10, Exceptional, (21 reviews)
"We loved our stay for Memorial Day weekend! It was the perfect space to unwind after a day of walking around historic Saint Charles. Our favorite spot was the back deck. Having the garage was so convenient and the space itself is really beautiful. The only thing we wish we had prepared for was a lack of basic kitchen cooking items. We bought breakfast food to cook but did not think to bring cooking oil/s&p. Would love to stay again sometime! We had a great weekend."
United States
Jennifer M.
The price is £226
includes taxes & fees
30 Aug - 31 Aug
Main Street 2BR Apartment with Garage and Deck
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

The Wildwood Hotel

The Wildwood Hotel

10/10 Excellent
"A great independent hotel in a good location. Room was spacious and clean. Front desk staff was helpful and friendly. Would definitely stay there again."
Kirk 1-night trip
Posted less than an hour ago
The Wildwood Hotel

Find out more about Defiance

Defiance Apartments information

Number of reviews
9,577
Accommodation
115 Apartments
Lowest Price
£57
Highest Price
£113

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . 2 Queen Beds | Non-Smoking, Kitchen: Located 18.7 mi/30.1 km away in Maryland Heights . Free WiFi and a Smart TV are included . Prime Loft of Main Street: Located in St. Charles , 19.2 mi/30.9 km away. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Historic Main St 1BR | Walk to Dining & Nightlife: 19.1 mi/30.7 km away in St. Charles . Amenities include a dining area . The Rustic Revival | Charming 2BR Retreat: It's located in St. Charles , 19 mi/30.6 km from Defiance. Includes free WiFi .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.