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Our top choices for Defiance apartments

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is £178
includes taxes & fees
12 Apr - 13 Apr
Duplex Hideaway in St. Charles, MO

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
Maryland Heights
9.6 out of 10, Exceptional, (4 reviews)
"It was an easy experience renting this place"
United States
Dominic M.
The price is £155
includes taxes & fees
12 Apr - 13 Apr
Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.0 out of 10, Wonderful, (33 reviews)
"Nice property.. Clean. "
United States
Belinda J.
The price is £147
includes taxes & fees
13 Apr - 14 Apr
Stay on Main Historic Studio

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (59 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is £208
includes taxes & fees
12 Apr - 13 Apr
Amazing Renovated Historic Loft on Main Street

Main Street Balcony Apartment

Main Street Balcony Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (36 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is £326
includes taxes & fees
13 Apr - 14 Apr
Main Street Balcony Apartment

Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
The price is £202
includes taxes & fees
4 May - 5 May
Stylish1BRStudioCleanQuietandCozy

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (17 reviews)
"Host was very welcoming and helpful when we have any questions no matter what time of day. The place was very quaint and comfy. We would highly recommend. "
United States
Chelsea L.
The price is £175
includes taxes & fees
12 Apr - 13 Apr
The Historic Bricks on Main

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (168 reviews)
"Host was very responsive and location was perfect"
United States
Peggy K.
The price is £196
includes taxes & fees
12 Apr - 13 Apr
The Lofts of North Main Street

The Bourbon & Brass | Speakeasy-Inspired 2BDR

The Bourbon & Brass | Speakeasy-Inspired 2BDR
St. Charles Historic District
The price is £244
includes taxes & fees
12 Apr - 13 Apr
The Bourbon & Brass | Speakeasy-Inspired 2BDR

1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.6 out of 10, Good, (8 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is £227
includes taxes & fees
12 Apr - 13 Apr
1st Capitol Mansion - Suite 401

2 Bdr Upstairs Apt Walking Distance to Main St

2 Bdr Upstairs Apt Walking Distance to Main St
Saint Charles
9.4 out of 10, Exceptional, (3 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is £218
includes taxes & fees
12 Apr - 13 Apr
2 Bdr Upstairs Apt Walking Distance to Main St

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (36 reviews)
"Great Stay and great location! "
United States
Angela
The price is £267
includes taxes & fees
13 Apr - 14 Apr
Historic Main St. Customs House Upstairs Apartment

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (107 reviews)
"This was a wonderful place for our St Charles stay - right in the heart of the historic downtown. Very clean and with nice character (exposed brick walls, tastefully decorated, etc). We had plenty of room fo the three of us, and our almost 12 year old kiddo LOVED having the loft upstairs to herself. If you are looking for a place to stay outside of St Louis, I highly recommend this location."
United States
Julie
The price is £208
includes taxes & fees
12 Apr - 13 Apr
Prime Loft of Main Street

The Lilly Pad House - Doddridge

The Lilly Pad House - Doddridge
Maryland Heights
The price is £331
includes taxes & fees
13 Apr - 14 Apr
The Lilly Pad House - Doddridge

AK`s STL Pearl Grey House - Game Room

AK`s STL Pearl Grey House - Game Room
Maryland Heights
9.0 out of 10, Wonderful, (8 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
The price is £310
includes taxes & fees
19 Apr - 20 Apr
AK`s STL Pearl Grey House - Game Room

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
9.8 out of 10, Exceptional, (17 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
The price is £186
includes taxes & fees
12 Apr - 13 Apr
Charming Duplex on Main

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
St. Louis MO
The price is £68
includes taxes & fees
19 Apr - 20 Apr
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
The price is £214
includes taxes & fees
12 Apr - 13 Apr
6th street 101 - Walk to Main St

2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (4 reviews)
"This place was perfect for our weekend getaway! Beautifully decorated and clean! It is also right next to everything in historic downtown Washington, so that we could walk everywhere. "
United States
Tammy H.
The price is £127
includes taxes & fees
12 May - 13 May
2nd Street Loft - Riverview

Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.8 out of 10, Excellent, (14 reviews)
"Great space! Very comfortable! "
United States
Mary H.
The price is £218
includes taxes & fees
12 Apr - 13 Apr
Walk to Main St | Pet-Friendly Apt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
219
Accommodation
103 Apartments
Lowest Price
£68
Highest Price
£331

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles . Free WiFi, a sofa bed and a Smart TV are included . Access to on-site laundry facilities is available on site . The Headliner Suite on Main Street: Located in St. Charles , 18.5 mi/29.7 km away. Includes a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Rhythm Loft Above the Honky Tonk: Located 19.1 mi/30.7 km away in St. Charles . Amenities include a Smart TV . Access to on-site laundry facilities is available on site . Backstage Loft Above Honky Tonk: Located in St. Charles , 19.1 mi/30.7 km from Defiance. Includes a Smart TV . Access to on-site laundry facilities is available on site .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Missouri River are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.