A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance apartments

Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed

Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed
St. Louis
9.0 out of 10, Wonderful, (13 reviews)
"This was absolutely perfect and reasonable pricing I surely will be back "
United States
David G.
The price is £80
includes taxes & fees
9 Aug - 10 Aug
Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed

Family Home: Game Room & Huge Yard, Airport

Family Home: Game Room & Huge Yard, Airport
Maryland Heights
10.0 out of 10, Exceptional, (1 review)
"Very nice"
United States
Steven S.
The price is £341
includes taxes & fees
13 Jul - 14 Jul
Family Home: Game Room & Huge Yard, Airport

Quiet Neighborhood-Near Eats & Shops-Airport!

Quiet Neighborhood-Near Eats & Shops-Airport!
Brookside
10.0 out of 10, Exceptional, (2 reviews)
"This was an awesome place for 9 of us- plenty of rooms to sleep and bathrooms. The renter was very kind"
United States
Janet
The price is £349
includes taxes & fees
22 Jul - 23 Jul
Quiet Neighborhood-Near Eats & Shops-Airport!

1 Queen Bed | Non-Smoking, Kitchen

1 Queen Bed | Non-Smoking, Kitchen
Westport
10.0 out of 10, Exceptional, (40 reviews)
"I really enjoy it here!"
United States
Anonymous traveller
The price is £74
includes taxes & fees
14 Jul - 15 Jul
1 Queen Bed | Non-Smoking, Kitchen

3BR Family+Game Retreat 8 min STL Airport/Westport

3BR Family+Game Retreat 8 min STL Airport/Westport
Maryland Heights
9.0 out of 10, Wonderful, (10 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
The price is £308
includes taxes & fees
13 Jul - 14 Jul
3BR Family+Game Retreat 8 min STL Airport/Westport

Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
The price is £158
includes taxes & fees
2 Aug - 3 Aug
Studio | Lovely Suite Close to Edward Jones!

Main Street Apartment

Main Street Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is £334
includes taxes & fees
14 Jul - 15 Jul
Main Street Apartment

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (112 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is £208
includes taxes & fees
19 Jul - 20 Jul
Prime Loft of Main Street

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (178 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
The price is £197
includes taxes & fees
20 Jul - 21 Jul
The Lofts of North Main Street

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (65 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is £210
includes taxes & fees
15 Jul - 16 Jul
Amazing Renovated Historic Loft on Main Street

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.2 out of 10, Wonderful, (36 reviews)
"From the welcome email with clear concise directions on how to enter with door codes to a dwelling that had everything I needed with a very comfortable bed, it was a great stay and I wanted for nothing."
United States
Jacob G.
The price is £175
includes taxes & fees
3 Aug - 4 Aug
Stay on Main Historic Studio

Historic Main St Apt | Private Garage

Historic Main St Apt | Private Garage
St. Charles Historic District
9.2 out of 10, Wonderful, (18 reviews)
"The location is excellent. The appartment is nice, spacious, comfortable, and practical. The parking spot is a big plus. Everything was perfect with our stay. Would stay again and highly recommedn."
United States
Bettina I.
The price is £255
includes taxes & fees
19 Jul - 20 Jul
Historic Main St Apt | Private Garage

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (19 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
The price is £177
includes taxes & fees
14 Jul - 15 Jul
The Historic Bricks on Main

The Global Getaway | World-Inspired 2-Bedroom Stay

The Global Getaway | World-Inspired 2-Bedroom Stay
St. Charles Historic District
The price is £224
includes taxes & fees
13 Jul - 14 Jul
The Global Getaway | World-Inspired 2-Bedroom Stay

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (38 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is £294
includes taxes & fees
19 Jul - 20 Jul
Historic Main St. Customs House Upstairs Apartment

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
9.8 out of 10, Exceptional, (6 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is £205
includes taxes & fees
16 Jul - 17 Jul
Duplex Hideaway in St. Charles, MO

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
10.0 out of 10, Exceptional, (22 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
The price is £209
includes taxes & fees
26 Jul - 27 Jul
Charming Duplex on Main

Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.6 out of 10, Excellent, (16 reviews)
"Property was as advertised. Perfect for my needs, clean, quiet and convenient. Loved Historic St. Charles. Would recommend anytime! Thank you! "
United States
Brian B.
The price is £247
includes taxes & fees
13 Jul - 14 Jul
Walk to Main St | Pet-Friendly Apt

1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is £187
includes taxes & fees
26 Jul - 27 Jul
1st Capitol Mansion - Suite 401

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (2 reviews)
"Excellent"
United States
Scott N.
The price is £216
includes taxes & fees
13 Jul - 14 Jul
6th street 101 - Walk to Main St
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
501
Accommodation
115 Apartments
Lowest Price
£74
Highest Price
£349

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: 1 Queen Bed | Non-Smoking, Kitchen: Situated in Maryland Heights , 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and a Smart TV . Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed: Located 20.7 mi/33.2 km away in Overland . Free WiFi, a balcony and a Smart TV are included . 2 Queen Beds | Non-Smoking, Kitchen: It's situated in Maryland Heights , 18.7 mi/30.1 km away. Includes free WiFi and a Smart TV . The Lofts of North Main Street: Located 19.2 mi/30.8 km away in St. Charles . Free WiFi, a sofa bed and a Smart TV are included . Access to on-site laundry facilities is available on site . 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: It's located in Maryland Heights , 18.7 mi/30.1 km from Defiance. Includes free WiFi and a Smart TV .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.