Photo by Skyy
Find Family-Friendly Hotels in Cape Girardeau, MO
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Cape Girardeau Family-Friendly Hotels
Top Cape Girardeau Family-Friendly Hotels
Our top choices for Cape Girardeau family-friendly hotels

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (985)
The price is £75
includes taxes & fees
7 Sept - 8 Sept

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1001)
The price is £86
includes taxes & fees
14 Sept - 15 Sept

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
9.0 out of 10, Wonderful, (1005)
The price is £58
includes taxes & fees
2 Sept - 3 Sept

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
10.0 out of 10, Exceptional, (219)

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (740)
The price is £92
includes taxes & fees
5 Sept - 6 Sept

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1003)
The price is £58
includes taxes & fees
31 Aug - 1 Sept

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
8.0 out of 10, Very good, (838)
The price is £70
includes taxes & fees
1 Sept - 2 Sept

Quality Inn
Quality Inn
7.0 out of 10, Good, (630)
The price is £48
includes taxes & fees
4 Sept - 5 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family-friendly hotels with free breakfast in Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
9.0 out of 10, Wonderful, (1005)
The price is £58
includes taxes & fees
2 Sept - 3 Sept
Family-friendly hotels with pools in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1013)
The price is £75
includes taxes & fees
2 Sept - 3 Sept
Family-friendly hotels with waterparks in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (140)
The price is £186
includes taxes & fees
30 Aug - 31 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Cape Girardeau
Top Cape Girardeau Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Nearby Cities
Choose Your Cape Girardeau Hotel Style
More accommodation types in Cape Girardeau
- Holiday Homes in Missouri
- Apartments in Missouri
- Cabin Rentals in Missouri
- Cottages in Missouri
- Lodges in Missouri
- Resorts in Missouri
- Chalets in Missouri
- Villas in Missouri
- B&B in Missouri
- Farmstay in Missouri
- Serviced Apartments in Missouri
- Caravan Parks in Missouri
- Inns in Missouri
- Hostels in Missouri
Hotels near popular Cape Girardeau Attractions
Explore more hotels
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Town House Inn Cape Giradreau
- Little Blue Cottage on Spanish
- Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"
- Rockwood Inn
- Loft Apartment Across From Semo University Houch Field House. Walk To Events
- Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
- Gorgeous 1856 Log Cabin, Completely Renovated
- Historical 'Kage House' Short Term Rental located in "Old Town Cape"
- 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
- Drury Inn & Suites Jackson MO
- Peaceful secluded cabin located near Horseshoe Lake