Beginning of main content

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Trending Hotels Near California Academy of Sciences

See all 474 Hotels near California Academy of Sciences

Get 200 Nectar points when you book your hotel

Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.

Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
Last booking: 41 minutes ago
100 others viewing this property now
4.3 out of 5 (6,469 reviews)

Located in Downtown San Francisco, this romantic hotel is within a 15-minute walk of Westfield San Francisco Centre, San Francisco Museum of Modern Art and Asian ...

£126

£126
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
Last booking: 1 hour ago
18 others viewing this property now
4.0 out of 5 (4,768 reviews)

Located in Downtown San Francisco, this hotel is within a 10-minute walk of Westfield San Francisco Centre and San Francisco Museum of Modern Art. Asian Art ...

£102

£102
Staypineapple at The Alise San Francisco

Staypineapple at The Alise San Francisco

580 Geary St, San Francisco
4.0 out of 5.0
Last booking: 4 hours ago
10 others viewing this property now
4.5 out of 5 (370 reviews)

Located in Downtown San Francisco, this hotel is within a 10-minute walk of Powell and Market Cable Car Turnaround and Warfield Theater. Grace Cathedral and ...

£108

£108
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
Last booking: 1 hour ago
49 others viewing this property now
4.0 out of 5 (4,447 reviews)

Located in Downtown San Francisco, this romantic hotel is within a 15-minute walk of Powell and Market Cable Car Turnaround, San Francisco Museum of Modern Art ...

£96

£96
Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco
5.0 out of 5.0
Last booking: 12 hours ago
22 others viewing this property now
4.6 out of 5 (371 reviews)

This family-friendly San Francisco hotel is located by the ocean, within a 15-minute walk of TransAmerica Pyramid and San Francisco Museum of Modern Art. Westfield ...

£204

£204
The Adrian

The Adrian

493 Eddy St, San Francisco
2.5 out of 5.0
Last booking: 2 days ago
8 others viewing this property now
1.5 out of 5 (2 reviews)

Located in Downtown San Francisco, this hotel is within a 10-minute walk of Asian Art Museum of San Francisco and Westfield San Francisco Centre. Louise Davies ...

£73

£73
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

433 Powell St, San Francisco
3.0 out of 5.0
Last booking: 1 hour ago
10 others viewing this property now
4.3 out of 5 (4,756 reviews)

Located in Downtown San Francisco, this hotel is within a 15-minute walk of Powell and Market Cable Car Turnaround, San Francisco Museum of Modern Art and Grace ...

£70

£70
Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco
4.0 out of 5.0
Last booking: 16 minutes ago
81 others viewing this property now
4.4 out of 5 (547 reviews)

Located in Downtown San Francisco, this hotel is within a 15-minute walk of Westfield San Francisco Centre, San Francisco Museum of Modern Art and Asian Art ...

£112

£112
The Marker San Francisco, a Joie de Vivre Hotel

The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco
4.0 out of 5.0
Last booking: 6 hours ago
39 others viewing this property now
4.4 out of 5 (2,182 reviews)

Located in Downtown San Francisco, this romantic hotel is within a 15-minute walk of Westfield San Francisco Centre, San Francisco Museum of Modern Art and Asian ...

£113

£113
Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco
4.0 out of 5.0
Last booking: 5 hours ago
69 others viewing this property now
4.0 out of 5 (3,491 reviews)

This family-friendly San Francisco hotel is located in the entertainment district, within a 10-minute walk of Westfield San Francisco Centre and San Francisco ...

£94

£94