Title: The 10 Best 5 Star Hotels in Southeast Iowa - 2025 Updated Prices | Expedia.co.uk [Southeast Iowa Travel Guide](https://expedia.co.uk/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.co.uk/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Holiday Rentals in Southeast Iowa](https://expedia.co.uk/Southeast-Iowa-Holiday-Rentals.d6234151.Travel-Guide-HolidayRentals)[Flights to Southeast Iowa](https://expedia.co.uk/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Southeast Iowa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Iowa.d6234151.Car-Hire-Guide)[Southeast Iowa Holidays](https://expedia.co.uk/Southeast-Iowa.d6234151.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/55b2c6dee1b7995ed1033756cd63ca06.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Southeast Iowa, United States of America ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Iowa 5 Star Hotels Tonight [26 Sept - 27 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2025-09-26&endDate=2025-09-27&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2025-09-27&endDate=2025-09-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2025-09-26&endDate=2025-09-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2025-10-03&endDate=2025-10-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Iowa 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Southeast-Iowa-Hotels.s50-0-d6234151.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Southeast-Iowa-Hotels.s50-0-d6234151.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southeast Iowa. ![Evans Holly Grove Inn B&B](https://images.trvl-media.com/lodging/24000000/23010000/23003900/23003876/2bddcaf2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Evans Holly Grove Inn B&B 616 Columbia Street, Burlington, IA £94 29 Sept - 30 Sept includes taxes & fees 9.6/10 Exceptional! (190 reviews) [](https://expedia.co.uk/Burlington-Hotels-Evans-Holly-Grove-Inn-Bed-And-Breakfast.h23003876.Hotel-Information) Still don't see what you're looking for? [See all properties in Southeast Iowa.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F09%2F2025&endDate=28%2F09%2F2025®ionId=6234151&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F09%2F2025&endDate=28%2F09%2F2025®ionId=6234151&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F09%2F2025&endDate=28%2F09%2F2025®ionId=6234151&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F09%2F2025&endDate=28%2F09%2F2025®ionId=6234151&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F09%2F2025&endDate=28%2F09%2F2025®ionId=6234151&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F09%2F2025&endDate=28%2F09%2F2025®ionId=6234151&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Southeast Iowa Explore the family-friendly area of Southeast Iowa—a scenic riverfront, shopping and sights from Battle of Athens State Historic Site to Ortho Landing and Wildlife Area. [See all hotels in Southeast Iowa](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11&adults=2®ionId=6234151) ![](https://mediaim.expedia.com/destination/1/55b2c6dee1b7995ed1033756cd63ca06.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Southeast Iowa Hotel Reviews ## Find out more about Southeast Iowa ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Southeast Iowa? > The amount you pay for a 5-star hotel in Southeast Iowa can vary according to when you want to travel and how long you plan to stay, among several factors. Use our price per night filter and other search tools to score the best deal on a high-end getaway. > > > > - Search for the lowest price per night from £94 ### What makes a hotel 5 stars in Southeast Iowa? > In Southeast Iowa, a hotel must provide a specific number of upscale amenities to be designated 5 stars. These may include gourmet restaurants, on-site gyms, saunas and spas, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their outstanding service. You can expect things like nightly turn-down services, in-room massages and concierge services. Some may also offer additional touches like a welcome gift. ### Are there any 5-star all-inclusive resorts in Southeast Iowa? > Use our convenient filters to find a luxury getaway in Southeast Iowa where most of what you need is included. Next, narrow down your results for resorts that have a rating of 5 stars and are deemed "All inclusive." The most important thing on the schedule at these stays? 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