Title: The 10 Best 5 Star Hotels in San Luis Obispo Wine Country - 2025 Updated Prices | Expedia.co.uk [San Luis Obispo Wine Country Travel Guide](https://expedia.co.uk/San-Luis-Obispo-Wine-Country.dx553248621593965865)[Hotels in San Luis Obispo Wine Country](https://expedia.co.uk/San-Luis-Obispo-Wine-Country-Hotels.d553248621593965865.Travel-Guide-Hotels)[Holiday Rentals in San Luis Obispo Wine Country](https://expedia.co.uk/San-Luis-Obispo-Wine-Country-Holiday-Rentals.d553248621593965865.Travel-Guide-HolidayRentals)[Flights to San Luis Obispo Wine Country](https://expedia.co.uk/Cheap-Flights-To-San-Luis-Obispo-Wine-Country.d553248621593965865.Travel-Guide-Flights)[San Luis Obispo Wine Country Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis-Obispo-Wine-Country.d553248621593965865.Car-Hire-Guide)[San Luis Obispo Wine Country Holidays](https://expedia.co.uk/San-Luis-Obispo-Wine-Country.d553248621593965865.Holidays-City-Breaks) ![San Luis Obispo featuring signage](https://images.trvl-media.com/place/6046822/0592c4aa-4a9e-471d-a3a9-00dd3ae098ae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in San Luis Obispo Wine Country, California - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Luis Obispo Wine Country 5 Star Hotels Tonight [26 Nov - 27 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-11-26&endDate=2025-11-27&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Nov - 28 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-11-27&endDate=2025-11-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-11-28&endDate=2025-11-30&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965865&startDate=2025-12-05&endDate=2025-12-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top San Luis Obispo Wine Country 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-San-Luis-Obispo-Wine-Country-Hotels.s50-0-d553248621593965865.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-San-Luis-Obispo-Wine-Country-Hotels.s50-0-d553248621593965865.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Luis Obispo Wine Country. ![Inn at the Pier Pismo Beach, Curio Collection by Hilton](https://images.trvl-media.com/lodging/19000000/18680000/18676000/18675941/w3838h2559x2y0-97fcea63_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Inn at the Pier Pismo Beach, Curio Collection by Hilton 601 Cypress Street Pismo Beach CA £149 2 Dec - 3 Dec includes taxes & fees 8.4/10 Very Good! (1,000 reviews) [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Inn-At-The-Pier.h18675941.Hotel-Information) ![Hotel San Luis Obispo](https://images.trvl-media.com/lodging/38000000/37240000/37233000/37232966/96137871_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel San Luis Obispo 877 Palm Street San Luis Obispo CA £255 30 Nov - 1 Dec includes taxes & fees 9.4/10 Exceptional! (541 reviews) [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Hotel-San-Luis-Obispo.h37232966.Hotel-Information) ![Vespera Resort on Pismo Beach, Autograph Collection](https://images.trvl-media.com/lodging/33000000/32870000/32867400/32867377/e8728690_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Vespera Resort on Pismo Beach, Autograph Collection 147 Stimson Ave Pismo Beach CA £201 2 Dec - 3 Dec includes taxes & fees 8.8/10 Excellent! (713 reviews) [](https://expedia.co.uk/San-Luis-Obispo-Hotels-Vespera-Resort-On-Pismo-Beach.h32867377.Hotel-Information) Still don't see what you're looking for? [See all properties in San Luis Obispo Wine Country.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F11%2F2025&endDate=28%2F11%2F2025®ionId=553248621593965865&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F11%2F2025&endDate=28%2F11%2F2025®ionId=553248621593965865&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F11%2F2025&endDate=28%2F11%2F2025®ionId=553248621593965865&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F11%2F2025&endDate=28%2F11%2F2025®ionId=553248621593965865&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F11%2F2025&endDate=28%2F11%2F2025®ionId=553248621593965865&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=27%2F11%2F2025&endDate=28%2F11%2F2025®ionId=553248621593965865&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about San Luis Obispo Wine Country Explore the seaside area of San Luis Obispo Wine Country—beaches, cycling trails and sights from Madonna Plaza Shopping Center to Cerro San Luis Obispo. [See all hotels in San Luis Obispo Wine Country](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11&adults=2®ionId=553248621593965865) ![San Luis Obispo featuring signage](https://images.trvl-media.com/place/6046822/0592c4aa-4a9e-471d-a3a9-00dd3ae098ae.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top San Luis Obispo Wine Country Hotel Reviews ## Find out more about San Luis Obispo Wine Country ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in San Luis Obispo Wine Country? > How much you pay for a 5-star hotel in San Luis Obispo Wine Country can vary according to the time of year you travel and how long you plan to be away, among a number of factors. Use our price per night filter and other search tools to find the best rate on an indulgent stay. > > > > - Search for the lowest price per night from £149 ### What makes a hotel 5 stars in San Luis Obispo Wine Country? > From high-end dining venues and 24/7 fitness centres to pools and the finest bedding, the 5-star experience in San Luis Obispo Wine Country is all about comfort and indulgence. But it calls for more than just top-notch perks to earn a 5-star rating. Stays also have to deliver outstanding services like in-room massages, dry cleaning and laundry and room service any time day or night. ### Are there any 5-star all-inclusive resorts in San Luis Obispo Wine Country? > Expedia's filters are the easiest way to find exactly what you want. Select "All inclusive" and "5-star" to see the most upscale hotels in San Luis Obispo Wine Country where your meals, accommodation, activities and entertainment are included in the upfront price. 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[Flights from London (LGW) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/lgw/sbp/london-to-san-luis-obispo) - [Flights from London (LHR) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/lhr/sbp/london-to-san-luis-obispo) - [Flights from Madrid (MAD) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/mad/sbp/madrid-to-san-luis-obispo) - [Flights from Manchester (MAN) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/man/sbp/manchester-to-san-luis-obispo) - [Flights from Massena (MSS) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/mss/sbp/massena-to-san-luis-obispo) - [Flights from Munich (MUC) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/muc/sbp/munich-to-san-luis-obispo) - [Flights from Portland (PDX) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/pdx/sbp/portland-to-san-luis-obispo) - [Flights from Phoenix (PHX) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/phx/sbp/phoenix-to-san-luis-obispo) - [Flights from Palm Springs (PSP) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/psp/sbp/palm-springs-to-san-luis-obispo) - [Flights from San Diego (SAN) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/san/sbp/san-diego-to-san-luis-obispo) - [Flights from Seattle (SEA) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/sea/sbp/seattle-to-san-luis-obispo) - [Flights from San Francisco (SFO) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/sfo/sbp/san-francisco-to-san-luis-obispo) - [Flights from Vancouver (YVR) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/yvr/sbp/vancouver-to-san-luis-obispo) - [Flights from Calgary (YYC) to San Luis Obispo (SBP)](https://www.expedia.co.uk/lp/flights/yyc/sbp/calgary-to-san-luis-obispo) - [Avila Beach Holidays](https://www.expedia.co.uk/Avila-Beach.d11911.Holidays-City-Breaks) - [Bubblegum Alley](https://www.expedia.co.uk/Bubblegum-Alley-Downtown-San-Luis-Obispo.d553248621532640000.Attraction) - [San Luis Obispo Holidays](https://www.expedia.co.uk/San-Luis-Obispo.d6046822.Holidays-City-Breaks) - [Visit San Luis Obispo](https://www.expedia.co.uk/San-Luis-Obispo.dx6046822) - [Wolff Vineyards](https://www.expedia.co.uk/Wolff-Vineyards-San-Luis-Obispo.d553248634340803878.Attraction) - [Car hire near Desire Sweet Shoppe](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Desire-Sweet-Shoppe.d553248621532639988.Car-Hire-Guide) - [Rental cars San Luis Obispo County Regional airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis-Obispo-County-Regional.d6031729.Car-Hire-Guide) - [Car hire San Luis Obispo](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Luis-Obispo.d6046822.Car-Hire-Guide) - [San Luis Obispo Holiday Rentals](https://www.expedia.co.uk/San-Luis-Obispo-Holiday-Rentals.d6046822.Travel-Guide-HolidayRentals) - [Things to do in Avila Beach](https://www.expedia.co.uk/Things-To-Do-In-Avila-Beach.d11911.Travel-Guide-Activities) - [Things to do in San Luis Obispo](https://www.expedia.co.uk/Things-To-Do-In-San-Luis-Obispo.d6046822.Travel-Guide-Activities) - [Book 5 Star Hotels in San Luis Obispo Wine Country on Expedia.com](https://www.expedia.com/5Star-San-Luis-Obispo-Wine-Country-Hotels.s50-0-d553248621593965865.Travel-Guide-Filter-Hotels)