Title: The 10 Best 5 Star Hotels in Lower Matecumbe Key - 2026 Updated Prices | Expedia.co.uk [Lower Matecumbe Key Travel Guide](https://expedia.co.uk/Lower-Matecumbe-Key.dx553248635975749077)[Hotels in Lower Matecumbe Key](https://expedia.co.uk/Lower-Matecumbe-Key-Hotels.d553248635975749077.Travel-Guide-Hotels)[Holiday Rentals in Lower Matecumbe Key](https://expedia.co.uk/Lower-Matecumbe-Key-Holiday-Rentals.d553248635975749077.Travel-Guide-HolidayRentals)[Flights to Lower Matecumbe Key](https://expedia.co.uk/Cheap-Flights-To-Lower-Matecumbe-Key.d553248635975749077.Travel-Guide-Flights)[Lower Matecumbe Key Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lower-Matecumbe-Key.d553248635975749077.Car-Hire-Guide)[Lower Matecumbe Key Holidays](https://expedia.co.uk/Lower-Matecumbe-Key.d553248635975749077.Holidays-City-Breaks) ![D1TFGW Beautiful Anne's Beach in summer with deck in Lower Matecumbe Key, Florida Keys, USA](https://images.trvl-media.com/place/553248635975749077/bacc300b-9bce-4a51-b8cb-bc1d50c7c5e1.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Lower Matecumbe Key, Islamorada - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lower Matecumbe Key 5 Star Hotels Tonight [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749077&startDate=2025-12-19&endDate=2025-12-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749077&startDate=2025-12-20&endDate=2025-12-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749077&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975749077&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lower Matecumbe Key 5-star hotels ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4608d7e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4cbd70d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/b210c979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa [](https://www.expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) Matecumbe 9.2/10 Wonderful (1270) "It was awesome, great service, staff members are helpful, clean and tidy room with excellent views!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sami £453 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/ab76abc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/b14e4dcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/9b3c41b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/f4aac8d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in the Keys [](https://www.expedia.co.uk/Tavernier-Hotels-Condo-In-The-Keys.h93061348.Hotel-Information) Tavernier 8.0/10 Very good (13) "Love the location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela [](https://www.expedia.co.uk/Tavernier-Hotels-Condo-In-The-Keys.h93061348.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/71ae5bc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/w1024h1021x0y3-63c47ce9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Villa, Canal View | Dining room](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/d702e54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Villa, Canal View | Living area | 75-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/8c99be49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront House with Boat Dock [](https://www.expedia.co.uk/Tavernier-Hotels-Waterfront-House-With-Boat-Dock.h109724487.Hotel-Information) Hammer Point 6.0/10 (1) "Covered porch was nice for time outside. Inside was in need of work. Closets unfinished, no place to put any luggage, advertises a king bed and a queen bed, but only had a king and a full, no tp, or tissue products when we arrived. None of the above were deal breakers but just allot of small things that add up to frustration." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew [](https://www.expedia.co.uk/Tavernier-Hotels-Waterfront-House-With-Boat-Dock.h109724487.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lower-Matecumbe-Key-Hotels.s50-0-d553248635975749077.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lower-Matecumbe-Key-Hotels.s50-0-d553248635975749077.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Matecumbe Key. ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/b1845555_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hawks Cay Resort 61 Hawks Cay Blvd Marathon FL £396 22 Dec - 23 Dec includes taxes & fees 8/10 Very Good! (1,000 reviews) [](https://expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) ![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Amara Cay Resort 80001 Overseas Hwy Islamorada FL £224 4 Jan - 5 Jan 2026 includes taxes & fees 8.8/10 Excellent! (1,266 reviews) [](https://expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 97000 Overseas Hwy Key Largo FL £378 8 Jan - 9 Jan 2026 includes taxes & fees 8.6/10 Excellent! (1,005 reviews) [](https://expedia.co.uk/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) Still don't see what you're looking for? [See all properties in Lower Matecumbe Key.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635975749077&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635975749077&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635975749077&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635975749077&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635975749077&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F12%2F2025&endDate=21%2F12%2F2025®ionId=553248635975749077&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Lower Matecumbe Key Venture to sights like Anne's Beach and Robbie’s of Islamorada as you discover Lower Matecumbe Key. [See all hotels in Lower Matecumbe Key](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03&adults=2®ionId=553248635975749077) ![D1TFGW Beautiful Anne's Beach in summer with deck in Lower Matecumbe Key, Florida Keys, USA](https://images.trvl-media.com/place/553248635975749077/bacc300b-9bce-4a51-b8cb-bc1d50c7c5e1.jpg?impolicy=fcrop&w=900&h=550&p=1&q=high) ## Top Lower Matecumbe Key Hotel Reviews ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg) ### Cheeca Lodge & Spa 10/10 Excellent "Everything was awsome" [](https://expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ## Find out more about Lower Matecumbe Key ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [1 Star Hotels in Dredgers Key ](https://www.expedia.co.uk/1Star-Dredgers-Key-Hotels.s10-0-d180165.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Key Haven ](https://www.expedia.co.uk/2Star-Key-Haven-Hotels.s20-0-d553248635976197997.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Boca Chica Key ](https://www.expedia.co.uk/3Star-Boca-Chica-Key-Hotels.s30-0-d553248635083916609.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Coconut Grove ](https://www.expedia.co.uk/3Star-Coconut-Grove-Miami-Hotels.s30-n11937-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Coral Gables ](https://www.expedia.co.uk/3Star-Coral-Gables-Hotels.s30-0-d7654.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Duck Key ](https://www.expedia.co.uk/3Star-Duck-Key-Hotels.s30-0-d184267.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Florida City ](https://www.expedia.co.uk/3Star-Florida-City-Hotels.s30-0-d8101.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Homestead ](https://www.expedia.co.uk/3Star-Homestead-Hotels.s30-0-d7744.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Marathon ](https://www.expedia.co.uk/3Star-Marathon-Hotels.s30-0-d2437.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Bahia Honda Key ](https://www.expedia.co.uk/4Star-Bahia-Honda-Key-Hotels.s40-0-d553248635083902001.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Coconut Grove ](https://www.expedia.co.uk/4Star-Coconut-Grove-Miami-Hotels.s40-n11937-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Coral Gables ](https://www.expedia.co.uk/4Star-Coral-Gables-Hotels.s40-0-d7654.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Duck Key ](https://www.expedia.co.uk/4Star-Duck-Key-Hotels.s40-0-d184267.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Florida City ](https://www.expedia.co.uk/4Star-Florida-City-Hotels.s40-0-d8101.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Homestead ](https://www.expedia.co.uk/4Star-Homestead-Hotels.s40-0-d7744.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Islamorada ](https://www.expedia.co.uk/4Star-Islamorada-Hotels.s40-0-d10768.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Marathon ](https://www.expedia.co.uk/4Star-Marathon-Hotels.s40-0-d2437.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Rockland Key ](https://www.expedia.co.uk/4Star-Rockland-Key-Hotels.s40-0-d553248635976197596.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Coconut Grove ](https://www.expedia.co.uk/5Star-Coconut-Grove-Miami-Hotels.s50-n11937-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Coral Gables ](https://www.expedia.co.uk/5Star-Coral-Gables-Hotels.s50-0-d7654.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Duck Key ](https://www.expedia.co.uk/5Star-Duck-Key-Hotels.s50-0-d184267.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Florida City ](https://www.expedia.co.uk/5Star-Florida-City-Hotels.s50-0-d8101.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Homestead ](https://www.expedia.co.uk/5Star-Homestead-Hotels.s50-0-d7744.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Islamorada ](https://www.expedia.co.uk/5Star-Islamorada-Hotels.s50-0-d10768.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Kendall ](https://www.expedia.co.uk/5Star-Kendall-Miami-Hotels.s50-n8226-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Key Largo ](https://www.expedia.co.uk/5Star-Key-Largo-Hotels.s50-0-d8369.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Little Havana ](https://www.expedia.co.uk/5Star-Little-Havana-Miami-Hotels.s50-n505226-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Marathon ](https://www.expedia.co.uk/5Star-Marathon-Hotels.s50-0-d2437.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Key Largo ](https://www.expedia.co.uk/5Star-North-Key-Largo-Hotels.s50-0-d553248635976475358.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Tingler Island ](https://www.expedia.co.uk/5Star-Tingler-Island-Hotels.s50-0-d553248635976196806.Travel-Guide-Filter-Hotels) - [Hotels near Bud n' Mary's Dive Center ](https://www.expedia.co.uk/Bud-N-Marys-Dive-Center-Hotels.0-l6069243-0.Travel-Guide-Filter-Hotels) - [Hotels near Florida Keys Brewing Co. ](https://www.expedia.co.uk/Florida-Keys-Brewing-Co-Hotels.0-l553248635997958830-0.Travel-Guide-Filter-Hotels) - [Apartments in Islamorada ](https://www.expedia.co.uk/Islamorada-Apartments.d10768-aaApartments.Travel-Guide-Accommodation) - [B&B in Islamorada ](https://www.expedia.co.uk/Islamorada-Bed-And-Breakfasts.d10768-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Adults Only Resorts & in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Adults-Only-Resorts.0-0-d10768-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Aimbridge Hospitality Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Aimbridge-Hospitality.0-0-d10768--bAimbridgeHospitality.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Beach-Hotels.0-0-d10768-tBeachHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Boutique-Hotel.0-0-d10768-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Budget-Hotels.0-0-d10768-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Family-Friendly-Hotel.0-0-d10768-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Gay-Friendly-Hotel.0-0-d10768-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Golf-Hotels.0-0-d10768-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hilton-Hotels.0-0-d10768--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hotels Suites in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-Suites.0-0-d10768-thotelsuites.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-A-Bar.0-0-d10768-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with a View in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-A-View.0-0-d10768-thotelwithaview.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Connecting-Rooms.0-0-d10768-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Early-Check-In.0-0-d10768-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Gym in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Gym.0-0-d10768-thotelwithgym.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Service in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Laundry-Service.0-0-d10768-thotelwithlaundryservice.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Hotels-With-Hot-Tubs.0-0-d10768-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Luxury-Hotel.0-0-d10768-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Pet-Friendly-Hotel.0-0-d10768-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Romantic-Hotel.0-0-d10768-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Spa-Hotels.0-0-d10768-tSpaHotels.Travel-Guide-Filter-Hotels) - [Hotels with Waterpark in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Waterpark-Hotel.0-0-d10768-twaterparkhotel.Travel-Guide-Filter-Hotels) - [Wedding Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Wedding-Hotel.0-0-d10768-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Yoga Hotels in Islamorada ](https://www.expedia.co.uk/Islamorada-Hotels-Yoga-Hotels.0-0-d10768-tYogaHotels.Travel-Guide-Filter-Hotels) - [Islamorada Hotels ](https://www.expedia.co.uk/Islamorada-Hotels.d10768.Travel-Guide-Hotels) - [Houseboats in Islamorada ](https://www.expedia.co.uk/Islamorada-Houseboats.d10768-aaHouseboats.Travel-Guide-Accommodation) - [Motels in Islamorada ](https://www.expedia.co.uk/Islamorada-Motels.d10768-aaMotels.Travel-Guide-Accommodation) - [Holiday Homes in Islamorada ](https://www.expedia.co.uk/Islamorada-Private-Holiday-Homes.d10768-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Villas in Islamorada ](https://www.expedia.co.uk/Islamorada-Villas.d10768-aaVillas.Travel-Guide-Accommodation) - [Layton Hotels ](https://www.expedia.co.uk/Layton-Hotels.d6177793.Travel-Guide-Hotels) - [Resorts in Lignumvitae Key Botanical State Park ](https://www.expedia.co.uk/Lignumvitae-Key-Botanical-State-Park-Hotel-Resorts.d553248621532652349-aaHotelResorts.Travel-Guide-Accommodation) - [Lignumvitae Key Botanical State Park Hotels ](https://www.expedia.co.uk/Lignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels) - [Holiday Homes in Lignumvitae Key Botanical State Park ](https://www.expedia.co.uk/Lignumvitae-Key-Botanical-State-Park-Private-Holiday-Homes.d553248621532652349-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Gay-Friendly Hotels in Long Key ](https://www.expedia.co.uk/Long-Key-Hotels-Gay-Friendly-Hotel.0-0-d177527-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Long Key Hotels ](https://www.expedia.co.uk/Long-Key-Hotels.d177527.Travel-Guide-Hotels) - [Benchmark Hotels in Lower Arsnicker Keys ](https://www.expedia.co.uk/Lower-Arsnicker-Keys-Hotels-Benchmark.0-0-d553248635975748872--bBenchmark.Travel-Guide-Filter-Hotels) - [Lower Matecumbe Beach Hotels ](https://www.expedia.co.uk/Lower-Matecumbe-Beach-Islamorada-Hotels.0-n553248635976195207-0.Travel-Guide-Filter-Hotels) - [Matecumbe Hotels ](https://www.expedia.co.uk/Matecumbe-Islamorada-Hotels.0-n855587555438403584-0.Travel-Guide-Filter-Hotels) - [Apartments in Upper Matecumbe Key ](https://www.expedia.co.uk/Upper-Matecumbe-Key-Apartments.d553248635975749648-aaApartments.Travel-Guide-Accommodation) - [Resorts in Upper Matecumbe Key ](https://www.expedia.co.uk/Upper-Matecumbe-Key-Hotel-Resorts.d553248635975749648-aaHotelResorts.Travel-Guide-Accommodation) - [Beach Resorts & in Upper Matecumbe Key ](https://www.expedia.co.uk/Upper-Matecumbe-Key-Hotels-Beach-Hotels.0-0-d553248635975749648-tBeachHotels.Travel-Guide-Filter-Hotels) - [Upper Matecumbe Key Hotels ](https://www.expedia.co.uk/Upper-Matecumbe-Key-Hotels.d553248635975749648.Travel-Guide-Hotels) - [Windley Key Hotels ](https://www.expedia.co.uk/Windley-Key-Hotels.d553248635976197663.Travel-Guide-Hotels) - [Flights to Islamorada ](https://www.expedia.co.uk/Cheap-Flights-To-Islamorada.d10768.Travel-Guide-Flights) - [Flights to Upper Matecumbe Key ](https://www.expedia.co.uk/Cheap-Flights-To-Upper-Matecumbe-Key.d553248635975749648.Travel-Guide-Flights) - [Flights to Windley Key ](https://www.expedia.co.uk/Cheap-Flights-To-Windley-Key.d553248635976197663.Travel-Guide-Flights) - [Flights from Islamorada ](https://www.expedia.co.uk/lp/flights/10768/flights-from-islamorada) - [Florida Keys Brewing Co. ](https://www.expedia.co.uk/Florida-Keys-Brewing-Co-Matecumbe.d553248635997958830.Attraction) - [Islamorada Holidays ](https://www.expedia.co.uk/Islamorada.d10768.Holidays-City-Breaks) - [Visit Islamorada ](https://www.expedia.co.uk/Islamorada.dx10768) - [Visit Layton ](https://www.expedia.co.uk/Layton.dx6177793) - [Visit Lignumvitae Key Botanical State Park ](https://www.expedia.co.uk/Lignumvitae-Key-Botanical-State-Park.dx553248621532652349) - [Visit Long Key ](https://www.expedia.co.uk/Long-Key.dx177527) - [Visit Upper Matecumbe Key ](https://www.expedia.co.uk/Upper-Matecumbe-Key.dx553248635975749648) - [All inclusive Holiday Packages Lignumvitae Key Botanical State Park ](https://www.expedia.co.uk/lp/theme-holidays/all-inclusive-holidays/553248621532652349/Lignumvitae-Key-Botanical-State-Park) - [Budget Rental Cars in Lower Arsnicker Keys ](https://www.expedia.co.uk/Budget-Car-Rentals-In-Lower-Arsnicker-Keys.d553248635975748872-c39.Car-Rental-Guide-Suppliers) - [Car hire Islamorada ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Islamorada.d10768.Car-Hire-Guide) - [Car hire Layton ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Layton.d6177793.Car-Hire-Guide) - [Drive-A-Matic Rental Cars in Windley Key ](https://www.expedia.co.uk/Drive-A-Matic-Car-Rentals-In-Windley-Key.d553248635976197663-c1082.Car-Rental-Guide-Suppliers) - [Easirent Rental Cars in Lower Arsnicker Keys ](https://www.expedia.co.uk/Easirent-Car-Rentals-In-Lower-Arsnicker-Keys.d553248635975748872-c1039.Car-Rental-Guide-Suppliers) - [Goldcar Key’n Go Rental Cars in Windley Key ](https://www.expedia.co.uk/Goldcar-Keyn-Go-Car-Rentals-In-Windley-Key.d553248635976197663-c1044.Car-Rental-Guide-Suppliers) - [Localiza Argentina Rental Cars in Windley Key ](https://www.expedia.co.uk/Localiza-Argentina-Car-Rentals-In-Windley-Key.d553248635976197663-c1097.Car-Rental-Guide-Suppliers) - [Midway Car Rental Rental Cars in Lower Arsnicker Keys ](https://www.expedia.co.uk/Midway-Car-Rental-Car-Rentals-In-Lower-Arsnicker-Keys.d553248635975748872-c27.Car-Rental-Guide-Suppliers) - [Islamorada Holiday Rentals ](https://www.expedia.co.uk/Islamorada-Holiday-Rentals.d10768.Travel-Guide-HolidayRentals) - [Things to do in Islamorada ](https://www.expedia.co.uk/Things-To-Do-In-Islamorada.d10768.Travel-Guide-Activities) - [Things to do in Windley Key ](https://www.expedia.co.uk/Things-To-Do-In-Windley-Key.d553248635976197663.Travel-Guide-Activities) - [Book 5 Star Hotels in Lower Matecumbe Key on Expedia.com ](https://www.expedia.com/5Star-Lower-Matecumbe-Key-Hotels.s50-0-d553248635975749077.Travel-Guide-Filter-Hotels)