Title: The 10 Best 5 Star Hotels in Lower Arsnicker Keys - 2026 Updated Prices | Expedia.co.uk [Lower Arsnicker Keys Travel Guide](https://expedia.co.uk/Lower-Arsnicker-Keys.dx553248635975748872)[Hotels in Lower Arsnicker Keys](https://expedia.co.uk/Lower-Arsnicker-Keys-Hotels.d553248635975748872.Travel-Guide-Hotels)[Holiday Rentals in Lower Arsnicker Keys](https://expedia.co.uk/Lower-Arsnicker-Keys-Holiday-Rentals.d553248635975748872.Travel-Guide-HolidayRentals)[Flights to Lower Arsnicker Keys](https://expedia.co.uk/Cheap-Flights-To-Lower-Arsnicker-Keys.d553248635975748872.Travel-Guide-Flights)[Lower Arsnicker Keys Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lower-Arsnicker-Keys.d553248635975748872.Car-Hire-Guide)[Lower Arsnicker Keys Holidays](https://expedia.co.uk/Lower-Arsnicker-Keys.d553248635975748872.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lower Arsnicker Keys 5 Star Hotels Tonight [23 Mar - 24 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748872&startDate=2026-03-23&endDate=2026-03-24&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [24 Mar - 25 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748872&startDate=2026-03-24&endDate=2026-03-25&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748872&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748872&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lower Arsnicker Keys 5-star hotels ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4608d7e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/b210c979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4cbd70d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/387633fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa [](https://www.expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) Matecumbe 9.2/10 Wonderful (1,299 reviews) "Place was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Greg £315 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lower-Arsnicker-Keys-Hotels.s50-0-d553248635975748872.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lower-Arsnicker-Keys-Hotels.s50-0-d553248635975748872.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Arsnicker Keys. ![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/4186365f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Amara Cay Resort 80001 Overseas Hwy Islamorada FL £247 20 Apr - 21 Apr includes taxes & fees 8.8/10 Excellent! (1,259 reviews) [](https://expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/8671ba74_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hawks Cay Resort 61 Hawks Cay Blvd Marathon FL £296 21 Apr - 22 Apr includes taxes & fees 8/10 Very Good! (1,002 reviews) [](https://expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) ![Islander Resort](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/f8d2863e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Islander Resort 82100 Overseas Highway Islamorada FL £326 22 Apr - 23 Apr includes taxes & fees 9.2/10 Wonderful! (1,005 reviews) [](https://expedia.co.uk/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information) Still don't see what you're looking for? [See all properties in Lower Arsnicker Keys.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F03%2F2026&endDate=25%2F03%2F2026®ionId=553248635975748872&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F03%2F2026&endDate=25%2F03%2F2026®ionId=553248635975748872&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F03%2F2026&endDate=25%2F03%2F2026®ionId=553248635975748872&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F03%2F2026&endDate=25%2F03%2F2026®ionId=553248635975748872&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F03%2F2026&endDate=25%2F03%2F2026®ionId=553248635975748872&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=24%2F03%2F2026&endDate=25%2F03%2F2026®ionId=553248635975748872&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Top Lower Arsnicker Keys Hotel Reviews ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4608d7e2_y.jpg) ### Cheeca Lodge & Spa 8/10 Good "Beautiful property! The staff was wonderful! We did have a small issue with housekeeping, there is a room service tray left by our front door upon check-in from prior guest and not picked up for two days. Also, we had asked for additional towels that never came. We will definitely be back though, as the location and resort itself is wonderful." [](https://expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ## Find out more about Lower Arsnicker Keys ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [1 Star Hotels in Dredgers Key ](https://www.expedia.co.uk/1Star-Dredgers-Key-Hotels.s10-0-d180165.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Key Haven ](https://www.expedia.co.uk/2Star-Key-Haven-Hotels.s20-0-d553248635976197997.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Boca Chica Key ](https://www.expedia.co.uk/3Star-Boca-Chica-Key-Hotels.s30-0-d553248635083916609.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Coconut Grove ](https://www.expedia.co.uk/3Star-Coconut-Grove-Miami-Hotels.s30-n11937-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Dredgers Key ](https://www.expedia.co.uk/3Star-Dredgers-Key-Hotels.s30-0-d180165.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Duck Key ](https://www.expedia.co.uk/3Star-Duck-Key-Hotels.s30-0-d184267.Travel-Guide-Filter-Hotels) - 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