Title: The 10 Best 5 Star Hotels in Lignumvitae Key Botanical State Park - 2025 Updated Prices | Expedia.co.uk [Lignumvitae Key Botanical State Park Travel Guide](https://expedia.co.uk/Lignumvitae-Key-Botanical-State-Park.dx553248621532652349)[Hotels in Lignumvitae Key Botanical State Park](https://expedia.co.uk/Lignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels)[Holiday Rentals in Lignumvitae Key Botanical State Park](https://expedia.co.uk/Lignumvitae-Key-Botanical-State-Park-Holiday-Rentals.d553248621532652349.Travel-Guide-HolidayRentals)[Flights to Lignumvitae Key Botanical State Park](https://expedia.co.uk/Cheap-Flights-To-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Travel-Guide-Flights)[Lignumvitae Key Botanical State Park Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Car-Hire-Guide)[Lignumvitae Key Botanical State Park Holidays](https://expedia.co.uk/Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/2/10889d62a4441e5635069303fb9c7975.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by RVOutlawz # Compare and book 5 Star hotels in Lignumvitae Key Botanical State Park, Islamorada ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lignumvitae Key Botanical State Park 5 Star Hotels Tonight [19 Sept - 20 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-09-19&endDate=2025-09-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-09-20&endDate=2025-09-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-09-19&endDate=2025-09-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-09-26&endDate=2025-09-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Lignumvitae Key Botanical State Park 5 Star Hotels ![Private beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/79d31a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/e32d7e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa Matecumbe 9.2/10 Wonderful (1205) "Great place to stay and the staff was great. " £123 includes taxes & fees 1 Oct - 2 Oct [](https://www.expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/9b3c41b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/5de75c93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/ab76abc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/0917a41a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in the Keys Tavernier 8.8/10 Excellent (9) "Thoroughly enjoyed our stay! The pool, beach area and pickleball courts were fantastic! Also enjoyed the premium cable. " [](https://www.expedia.co.uk/Tavernier-Hotels-Condo-In-The-Keys.h93061348.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/691ffb10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, memory-foam beds](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/478c87a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/4e0d8909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![75-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/e85faba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront House with Boat Dock Hammer Point 6.0/10 (1) "Covered porch was nice for time outside. Inside was in need of work. Closets unfinished, no place to put any luggage, advertises a king bed and a queen bed, but only had a king and a full, no tp, or tissue products when we arrived. None of the above were deal breakers but just allot of small things that add up to frustration." [](https://www.expedia.co.uk/Tavernier-Hotels-Waterfront-House-With-Boat-Dock.h109724487.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lignumvitae-Key-Botanical-State-Park-Hotels.s50-0-d553248621532652349.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Lignumvitae-Key-Botanical-State-Park-Hotels.s50-0-d553248621532652349.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lignumvitae Key Botanical State Park. ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/b1845555_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hawks Cay Resort 61 Hawks Cay Blvd, Marathon, FL £261 29 Sept - 30 Sept includes taxes & fees 8/10 Very Good! (1,004 reviews) [](https://expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 97000 Overseas Hwy, Key Largo, FL £229 25 Sept - 26 Sept includes taxes & fees 8.6/10 Excellent! (1,012 reviews) [](https://expedia.co.uk/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Amara Cay Resort 80001 Overseas Hwy, Islamorada, FL £182 22 Sept - 23 Sept includes taxes & fees 8.8/10 Excellent! (1,247 reviews) [](https://expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) Still don't see what you're looking for? [See all properties in Lignumvitae Key Botanical State Park.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F09%2F2025&endDate=21%2F09%2F2025®ionId=553248621532652349&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F09%2F2025&endDate=21%2F09%2F2025®ionId=553248621532652349&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F09%2F2025&endDate=21%2F09%2F2025®ionId=553248621532652349&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F09%2F2025&endDate=21%2F09%2F2025®ionId=553248621532652349&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F09%2F2025&endDate=21%2F09%2F2025®ionId=553248621532652349&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=20%2F09%2F2025&endDate=21%2F09%2F2025®ionId=553248621532652349&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Lignumvitae Key Botanical State Park Explore the seaside area of Lignumvitae Key Botanical State Park—beaches, fishing spots and sights from Everglades National Park to Indian Key Historic State Park. [See all hotels in Lignumvitae Key Botanical State Park](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-03&endDate=2025-10-04&adults=2®ionId=553248621532652349) ![](https://mediaim.expedia.com/destination/2/10889d62a4441e5635069303fb9c7975.jpg?impolicy=fcrop&w=900&h=675&p=1&q=high) Photo by RVOutlawz ## Top Lignumvitae Key Botanical State Park Hotel Reviews ![Cheeca Lodge & Spa](//images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg) ### Cheeca Lodge & Spa 10/10 Excellent "Exceptional customer service, a plethora of activities and in a central location with many desirable businesses within a close reach." [](https://expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ## Find out more about Lignumvitae Key Botanical State Park ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Lignumvitae Key Botanical State Park? > The amount you pay for a 5-star hotel in Lignumvitae Key Botanical State Park can vary according to the time of year you travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to land the best rate on a luxurious stay. > > > > - Search for the lowest price per night from £182 ### What makes a hotel 5 stars in Lignumvitae Key Botanical State Park? > In Lignumvitae Key Botanical State Park, a hotel must provide a certain number of upscale amenities to be designated 5 stars. These can include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their guest-centric service. You can expect things like concierge services, in-room massages and nightly turn-down services. Some may even offer thoughtful touches like a welcome gift. ### Are there any 5-star all-inclusive resorts in Lignumvitae Key Botanical State Park? > Find a luxury stay that includes your room, meals, activities and entertainment in Lignumvitae Key Botanical State Park with the help of our filter tool. Search for resorts rated 5 stars and select the "All inclusive" filter. Double-check what's included in the purchase price. That way, you can take full advantage of the premium perks on offer as soon as you arrive. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [3 Star Hotels in Boca Chica Key](https://www.expedia.co.uk/3Star-Boca-Chica-Key-Hotels.s30-0-d553248635083916609.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Coconut Grove](https://www.expedia.co.uk/3Star-Coconut-Grove-Miami-Hotels.s30-n11937-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Coral Gables](https://www.expedia.co.uk/3Star-Coral-Gables-Hotels.s30-0-d7654.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Duck Key](https://www.expedia.co.uk/3Star-Duck-Key-Hotels.s30-0-d184267.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Florida City](https://www.expedia.co.uk/3Star-Florida-City-Hotels.s30-0-d8101.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Homestead](https://www.expedia.co.uk/3Star-Homestead-Hotels.s30-0-d7744.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Marathon](https://www.expedia.co.uk/3Star-Marathon-Hotels.s30-0-d2437.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Bahia Honda Key](https://www.expedia.co.uk/4Star-Bahia-Honda-Key-Hotels.s40-0-d553248635083902001.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Coconut Grove](https://www.expedia.co.uk/4Star-Coconut-Grove-Miami-Hotels.s40-n11937-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Coral Gables](https://www.expedia.co.uk/4Star-Coral-Gables-Hotels.s40-0-d7654.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Duck Key](https://www.expedia.co.uk/4Star-Duck-Key-Hotels.s40-0-d184267.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Florida City](https://www.expedia.co.uk/4Star-Florida-City-Hotels.s40-0-d8101.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Homestead](https://www.expedia.co.uk/4Star-Homestead-Hotels.s40-0-d7744.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Islamorada](https://www.expedia.co.uk/4Star-Islamorada-Hotels.s40-0-d10768.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Marathon](https://www.expedia.co.uk/4Star-Marathon-Hotels.s40-0-d2437.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Rockland Key](https://www.expedia.co.uk/4Star-Rockland-Key-Hotels.s40-0-d553248635976197596.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Brickell](https://www.expedia.co.uk/5Star-Brickell-Miami-Hotels.s50-n6240961-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Coconut Grove](https://www.expedia.co.uk/5Star-Coconut-Grove-Miami-Hotels.s50-n11937-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Coral Gables](https://www.expedia.co.uk/5Star-Coral-Gables-Hotels.s50-0-d7654.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Duck Key](https://www.expedia.co.uk/5Star-Duck-Key-Hotels.s50-0-d184267.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Florida City](https://www.expedia.co.uk/5Star-Florida-City-Hotels.s50-0-d8101.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Homestead](https://www.expedia.co.uk/5Star-Homestead-Hotels.s50-0-d7744.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Islamorada](https://www.expedia.co.uk/5Star-Islamorada-Hotels.s50-0-d10768.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Kendall](https://www.expedia.co.uk/5Star-Kendall-Miami-Hotels.s50-n8226-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Key Largo](https://www.expedia.co.uk/5Star-Key-Largo-Hotels.s50-0-d8369.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Little Havana](https://www.expedia.co.uk/5Star-Little-Havana-Miami-Hotels.s50-n505226-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Marathon](https://www.expedia.co.uk/5Star-Marathon-Hotels.s50-0-d2437.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Key Largo](https://www.expedia.co.uk/5Star-North-Key-Largo-Hotels.s50-0-d553248635976475358.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Tingler Island](https://www.expedia.co.uk/5Star-Tingler-Island-Hotels.s50-0-d553248635976196806.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Virginia Key Beach Park](https://www.expedia.co.uk/5Star-Virginia-Key-Beach-Park-Hotels.s50-0-d553248621532653053.Travel-Guide-Filter-Hotels) - [Hotels near Bud n' Mary's Dive Center](https://www.expedia.co.uk/Bud-N-Marys-Dive-Center-Hotels.0-l6069243-0.Travel-Guide-Filter-Hotels) - [Hotels near Florida Keys Brewing Co.](https://www.expedia.co.uk/Florida-Keys-Brewing-Co-Hotels.0-l553248635997958830-0.Travel-Guide-Filter-Hotels) - [Apartments in Islamorada](https://www.expedia.co.uk/Islamorada-Apartments.d10768-aaApartments.Travel-Guide-Accommodation) - [B&B in Islamorada](https://www.expedia.co.uk/Islamorada-Bed-And-Breakfasts.d10768-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Adults Only Resorts & in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Adults-Only-Resorts.0-0-d10768-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Aimbridge Hospitality Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Aimbridge-Hospitality.0-0-d10768--bAimbridgeHospitality.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Beach-Hotels.0-0-d10768-tBeachHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Boutique-Hotel.0-0-d10768-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Budget-Hotels.0-0-d10768-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Family-Friendly-Hotel.0-0-d10768-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Gay-Friendly-Hotel.0-0-d10768-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Golf-Hotels.0-0-d10768-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hilton-Hotels.0-0-d10768--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hotels Suites in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-Suites.0-0-d10768-thotelsuites.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-A-Bar.0-0-d10768-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with a View in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-A-View.0-0-d10768-thotelwithaview.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Connecting-Rooms.0-0-d10768-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Early-Check-In.0-0-d10768-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Gym in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Gym.0-0-d10768-thotelwithgym.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Service in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotel-With-Laundry-Service.0-0-d10768-thotelwithlaundryservice.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Hotels-With-Hot-Tubs.0-0-d10768-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Luxury-Hotel.0-0-d10768-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Pet-Friendly-Hotel.0-0-d10768-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Romantic-Hotel.0-0-d10768-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Spa-Hotels.0-0-d10768-tSpaHotels.Travel-Guide-Filter-Hotels) - [Hotels with Waterpark in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Waterpark-Hotel.0-0-d10768-twaterparkhotel.Travel-Guide-Filter-Hotels) - [Wedding Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Wedding-Hotel.0-0-d10768-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Yoga Hotels in Islamorada](https://www.expedia.co.uk/Islamorada-Hotels-Yoga-Hotels.0-0-d10768-tYogaHotels.Travel-Guide-Filter-Hotels) - [Islamorada Hotels](https://www.expedia.co.uk/Islamorada-Hotels.d10768.Travel-Guide-Hotels) - [Houseboats in Islamorada](https://www.expedia.co.uk/Islamorada-Houseboats.d10768-aaHouseboats.Travel-Guide-Accommodation) - [Motels in Islamorada](https://www.expedia.co.uk/Islamorada-Motels.d10768-aaMotels.Travel-Guide-Accommodation) - [Holiday Homes in Islamorada](https://www.expedia.co.uk/Islamorada-Private-Holiday-Homes.d10768-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Villas in Islamorada](https://www.expedia.co.uk/Islamorada-Villas.d10768-aaVillas.Travel-Guide-Accommodation) - [Layton Hotels](https://www.expedia.co.uk/Layton-Hotels.d6177793.Travel-Guide-Hotels) - [Benchmark Hotels in Lower Arsnicker Keys](https://www.expedia.co.uk/Lower-Arsnicker-Keys-Hotels-Benchmark.0-0-d553248635975748872--bBenchmark.Travel-Guide-Filter-Hotels) - [Lower Matecumbe Beach Hotels](https://www.expedia.co.uk/Lower-Matecumbe-Beach-Islamorada-Hotels.0-n553248635976195207-0.Travel-Guide-Filter-Hotels) - [Apartments in Lower Matecumbe Key](https://www.expedia.co.uk/Lower-Matecumbe-Key-Apartments.d553248635975749077-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Lower Matecumbe Key](https://www.expedia.co.uk/Lower-Matecumbe-Key-Condos.d553248635975749077-aaCondos.Travel-Guide-Accommodation) - [Cottages in Lower Matecumbe Key](https://www.expedia.co.uk/Lower-Matecumbe-Key-Cottages.d553248635975749077-aaCottages.Travel-Guide-Accommodation) - [Inns in Lower Matecumbe Key](https://www.expedia.co.uk/Lower-Matecumbe-Key-Inns.d553248635975749077-aaInns.Travel-Guide-Accommodation) - [Matecumbe Hotels](https://www.expedia.co.uk/Matecumbe-Islamorada-Hotels.0-n855587555438403584-0.Travel-Guide-Filter-Hotels) - [Apartments in Upper Matecumbe Key](https://www.expedia.co.uk/Upper-Matecumbe-Key-Apartments.d553248635975749648-aaApartments.Travel-Guide-Accommodation) - [Resorts in Upper Matecumbe Key](https://www.expedia.co.uk/Upper-Matecumbe-Key-Hotel-Resorts.d553248635975749648-aaHotelResorts.Travel-Guide-Accommodation) - [Beach Resorts & in Upper Matecumbe Key](https://www.expedia.co.uk/Upper-Matecumbe-Key-Hotels-Beach-Hotels.0-0-d553248635975749648-tBeachHotels.Travel-Guide-Filter-Hotels) - [Upper Matecumbe Key Hotels](https://www.expedia.co.uk/Upper-Matecumbe-Key-Hotels.d553248635975749648.Travel-Guide-Hotels) - [Venetian Shores Hotels](https://www.expedia.co.uk/Venetian-Shores-Islamorada-Hotels.0-n553248635976470270-0.Travel-Guide-Filter-Hotels) - [Windley Key Hotels](https://www.expedia.co.uk/Windley-Key-Hotels.d553248635976197663.Travel-Guide-Hotels) - [Flights to Islamorada](https://www.expedia.co.uk/Cheap-Flights-To-Islamorada.d10768.Travel-Guide-Flights) - [Flights to Upper Matecumbe Key](https://www.expedia.co.uk/Cheap-Flights-To-Upper-Matecumbe-Key.d553248635975749648.Travel-Guide-Flights) - [Flights to Windley Key](https://www.expedia.co.uk/Cheap-Flights-To-Windley-Key.d553248635976197663.Travel-Guide-Flights) - [Flights from Islamorada](https://www.expedia.co.uk/lp/flights/10768/flights-from-islamorada) - [Florida Keys Brewing Co.](https://www.expedia.co.uk/Florida-Keys-Brewing-Co-Matecumbe.d553248635997958830.Attraction) - [Islamorada Holidays](https://www.expedia.co.uk/Islamorada.d10768.Holidays-City-Breaks) - [Visit Islamorada](https://www.expedia.co.uk/Islamorada.dx10768) - [Visit Upper Matecumbe Key](https://www.expedia.co.uk/Upper-Matecumbe-Key.dx553248635975749648) - [Ace Rental Cars in Windley Key](https://www.expedia.co.uk/Ace-Car-Rentals-In-Windley-Key.d553248635976197663-c2.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Lower Arsnicker Keys](https://www.expedia.co.uk/Budget-Car-Rentals-In-Lower-Arsnicker-Keys.d553248635975748872-c39.Car-Rental-Guide-Suppliers) - [Car hire Islamorada](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Islamorada.d10768.Car-Hire-Guide) - [Discount Car Rentals Rental Cars in Lower Matecumbe Key](https://www.expedia.co.uk/Discount-Car-Rentals-Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077-c11.Car-Rental-Guide-Suppliers) - [Drive-A-Matic Rental Cars in Windley Key](https://www.expedia.co.uk/Drive-A-Matic-Car-Rentals-In-Windley-Key.d553248635976197663-c1082.Car-Rental-Guide-Suppliers) - [Easirent Rental Cars in Lower Arsnicker Keys](https://www.expedia.co.uk/Easirent-Car-Rentals-In-Lower-Arsnicker-Keys.d553248635975748872-c1039.Car-Rental-Guide-Suppliers) - [Goldcar Key’n Go Rental Cars in Windley Key](https://www.expedia.co.uk/Goldcar-Keyn-Go-Car-Rentals-In-Windley-Key.d553248635976197663-c1044.Car-Rental-Guide-Suppliers) - [Localiza Argentina Rental Cars in Windley Key](https://www.expedia.co.uk/Localiza-Argentina-Car-Rentals-In-Windley-Key.d553248635976197663-c1097.Car-Rental-Guide-Suppliers) - [Megadrive Rental Cars in Lower Matecumbe Key](https://www.expedia.co.uk/MegaDrive-Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077-c1074.Car-Rental-Guide-Suppliers) - [Midway Car Rental Rental Cars in Lower Arsnicker Keys](https://www.expedia.co.uk/Midway-Car-Rental-Car-Rentals-In-Lower-Arsnicker-Keys.d553248635975748872-c27.Car-Rental-Guide-Suppliers) - [Record Rent A Car Rental Cars in Lower Matecumbe Key](https://www.expedia.co.uk/Record-Rent-A-Car-Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077-c30.Car-Rental-Guide-Suppliers) - [U-Save Rental Cars in Lower Matecumbe Key](https://www.expedia.co.uk/U-Save-Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077-c34.Car-Rental-Guide-Suppliers) - [Islamorada Holiday Rentals](https://www.expedia.co.uk/Islamorada-Holiday-Rentals.d10768.Travel-Guide-HolidayRentals) - [Things to do in Islamorada](https://www.expedia.co.uk/Things-To-Do-In-Islamorada.d10768.Travel-Guide-Activities) - [Things to do in Windley Key](https://www.expedia.co.uk/Things-To-Do-In-Windley-Key.d553248635976197663.Travel-Guide-Activities) - [Book 5 Star Hotels in Lignumvitae Key Botanical State Park on Expedia.com](https://www.expedia.com/5Star-Lignumvitae-Key-Botanical-State-Park-Hotels.s50-0-d553248621532652349.Travel-Guide-Filter-Hotels)