A coastal landscape with grassy dunes, a sandy beach, and a calm sea.

Compare and book 5 Star hotels in Harbor Island, South Carolina

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Harbor Island 5 Star Hotels

Tonight
13 Sept - 14 Sept
Tomorrow
14 Sept - 15 Sept
Next weekend
18 Sept - 20 Sept
In two weeks
25 Sept - 27 Sept

Our top choices for Harbor Island 5-star hotels

A two-story white colonial-style building with a central entrance, columns, and a balcony on the upper floor.
A bathroom with a white vanity, a large mirror, and a hanging light fixture.
A traditional living room with a fireplace, two sofas, a coffee table, and a bookshelf.
A traditional living room with wooden paneled walls, a staircase, and two sofas.

1. Anchorage 1770

Anchorage 1770
Historic District
United States
Patricia
£194
includes taxes & fees
14 Sept - 15 Sept
Anchorage 1770
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Harbor Island.
The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa

2 Grasslawn Ave Hilton Head Island SC
£210
13 Oct - 14 Oct
includes taxes & fees
8.6/10 Excellent! (1,006 reviews)
The Westin Hilton Head Island Resort & Spa
Rhett House Inn

Rhett House Inn

1009 Craven St Beaufort SC
£150
14 Sept - 15 Sept
includes taxes & fees
9.2/10 Wonderful! (694 reviews)
Rhett House Inn
Circa 1785

Circa 1785

701 Greene St Beaufort SC
£139
14 Sept - 15 Sept
includes taxes & fees
9.6/10 Exceptional! (183 reviews)
Circa 1785
Still don't see what you're looking for?
See all properties in Harbor Island.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Harbor Island

Pristine beaches invite long walks at low tide when Harbour Island's shoreline reveals its hidden treasures. Rent a kayak to explore the salt marshes or take a short trip to Hunting Island State Park's iconic lighthouse.

See all hotels in Harbor Island
An aerial view of a river delta with multiple islands and a bridge in the distance.

Top Harbor Island Hotel Reviews

Find out more about Harbor Island

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Harbour Island?
The amount you pay for a 5-star hotel in Harbour Island can vary depending on when you prefer to travel and how long you plan to be away, among other factors. Take advantage of our price per night filter and other search tools to find the best deal on a high-end getaway.
  • Search for the lowest price per night from £139
What makes a hotel 5 stars in Harbour Island?
In Harbour Island, a hotel must provide a certain number of high-end amenities to earn a 5-star rating. These can include on-site gyms, saunas and spas, gourmet restaurants, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary standard of service. You can look forward to things like nightly turn-down services, concierge services and in-room massages. Some may even offer special touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Harbour Island?
Expedia's filters are the quickest way to narrow down what you want. Check the "All inclusive" and "5-star" boxes to show the most luxurious hotels in Harbour Island where your room, meals, entertainment and activities are included in the upfront price. At these escapes, your holiday is absolute indulgence from the moment you pull up to the entrance.

Explore a world of travel with Expedia