Search Hotels in Oyster Reef, Hilton Head Island

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
15 May - 17 May
Next weekend
22 May - 24 May

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Oyster Reef hotels

Basic Room, Multiple Beds, Non Smoking | Free WiFi, bed sheets

Simple Rewards Inn

Simple Rewards Inn
2.5 star property
Mid Island, 2.1 mi from Oyster Reef
8.8 out of 10, Excellent, (1,012 reviews)
"Clean room, fabulous staff, available parking "
United States
Diego
The price is £74
includes taxes & fees
19 May - 20 May
Simple Rewards Inn
Property grounds

Beaufort Inn

Beaufort Inn
3.5 star property
13.3 mi from Oyster Reef
9.0 out of 10, Wonderful, (1,001 reviews)
"Lovely property in great location, convenient to dining and shops. Loved walking the grounds and the fragrance of jasmine. Would definitely stay again."
United States
DeAnn
The price is £127
includes taxes & fees
14 Jun - 15 Jun
Beaufort Inn
Terrace/patio

607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort
2.5 star property
13.3 mi from Oyster Reef
9.8 out of 10, Exceptional, (106 reviews)
"What a beautiful inn located with walking distance to downtown and the bridge to Lady Island (which you can traverse by foot). The staff, amenities and rooms are perfect. Thank you for such a wonderful stay! We cannot wait to return!"
United States
Mickey
The price is £140
includes taxes & fees
18 May - 19 May
607 Bay Inn Downtown Beaufort
Beach/ocean view

DeSoto Beach Hotel

DeSoto Beach Hotel
3.0 star property
17.7 mi from Oyster Reef
8.4 out of 10, Very good, (1,012 reviews)
"The breakfast was good. "
United States
Terrie
The price is £140
includes taxes & fees
17 May - 18 May
DeSoto Beach Hotel
Studio Suite, 1 King Bed with Sofa bed | In-room safe, iron/ironing board, WiFi, bed sheets

Palmera Inn and Suites

Palmera Inn and Suites
3.0 star property
South End, 5.6 mi from Oyster Reef
9.0 out of 10, Wonderful, (1,312 reviews)
"Amazing location!!!"
United States
SaRa
The price is £109
includes taxes & fees
24 May - 25 May
Palmera Inn and Suites
Egyptian cotton sheets, premium bedding, pillow-top beds

The Emerald Boutique Stays

The Emerald Boutique Stays
2.5 star property
13.5 mi from Oyster Reef
9.2 out of 10, Wonderful, (259 reviews)
"convenient location, easy access, and very comfortable bed!"
United States
Tim
The price is £141
includes taxes & fees
18 May - 19 May
The Emerald Boutique Stays
Exterior

Rhett House Inn

Rhett House Inn
4.0 star property
13.4 mi from Oyster Reef
9.2 out of 10, Wonderful, (669 reviews)
"Everyone was really wonderful. "
United States
Kathrine
The price is £137
includes taxes & fees
17 May - 18 May
Rhett House Inn
Lobby

Best Western Plus Bluffton / Hilton Head Hotel

Best Western Plus Bluffton / Hilton Head Hotel
2.5 star property
13.7 mi from Oyster Reef
9.4 out of 10, Exceptional, (229 reviews)
"Front desk girl was very nice"
United States
Donald
The price is £97
includes taxes & fees
21 May - 22 May
Best Western Plus Bluffton / Hilton Head Hotel
Apartment (1 Bedroom) | Interior

Beachfront Condo w/ Pool Access in Hilton Head!

Beachfront Condo w/ Pool Access in Hilton Head!
4.0 star property
North Forest Beach, 7.3 mi from Oyster Reef
10.0 out of 10, Exceptional, (1 review)
The price is £255
includes taxes & fees
21 May - 22 May
Beachfront Condo w/ Pool Access in Hilton Head!
Meeting facility

Hotel Tybee

Hotel Tybee
2.5 star property
18.8 mi from Oyster Reef
7.6 out of 10, Good, (1,167 reviews)
"It is always a pleasure to stay at Hotel Tybee!"
United States
Karla
The price is £184
includes taxes & fees
17 May - 18 May
Hotel Tybee
Exterior detail

Royal Palms Motel

Royal Palms Motel
2.0 star property
18.3 mi from Oyster Reef
8.8 out of 10, Excellent, (211 reviews)
"Great staff and great motel"
United States
Martha
The price is £132
includes taxes & fees
18 May - 19 May
Royal Palms Motel
Exterior

Spark by Hilton Bluffton Hilton Head Island

Spark by Hilton Bluffton Hilton Head Island
2.5 star property
8.8 mi from Oyster Reef
8.4 out of 10, Very good, (211 reviews)
"Ample parking. Great location"
United States
Kunka
The price is £82
includes taxes & fees
31 May - 1 Jun
Spark by Hilton Bluffton Hilton Head Island
Courtyard

Dunes Inn & Suites

Dunes Inn & Suites
2.0 star property
18.8 mi from Oyster Reef
8.0 out of 10, Very good, (1,001 reviews)
"Loved staying here"
United States
Melanie
The price is £125
includes taxes & fees
17 May - 18 May
Dunes Inn & Suites
Business centre

Best Western Sea Island Inn

Best Western Sea Island Inn
2.5 star property
13.3 mi from Oyster Reef
9.6 out of 10, Exceptional, (1,001 reviews)
"Really enjoyed our stay. "
United States
Debra
The price is £136
includes taxes & fees
26 May - 27 May
Best Western Sea Island Inn
Gym

City Loft Hotel

City Loft Hotel
3.5 star property
13.4 mi from Oyster Reef
9.6 out of 10, Exceptional, (808 reviews)
"Clean room, wonderful staff, and excellent location. Coffee shop on site is fantastic. Highly recommend!"
United States
Camille
The price is £133
includes taxes & fees
17 May - 18 May
City Loft Hotel
Exterior

Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC
2.5 star property
13.8 mi from Oyster Reef
9.0 out of 10, Wonderful, (815 reviews)
"Convenient to downtown Beaufort with better prices than other hotels"
United States
Allen
The price is £83
includes taxes & fees
25 May - 26 May
Tru by Hilton Beaufort, SC
Exterior

Hilton Garden Inn Hilton Head

Hilton Garden Inn Hilton Head
3.0 star property
5.2 mi from Oyster Reef
8.6 out of 10, Excellent, (1,011 reviews)
"Beautiful hotel I. The staff was very friendly and welcoming and I would highly recommend it"
United States
Lisa
The price is £114
includes taxes & fees
25 May - 26 May
Hilton Garden Inn Hilton Head
Exterior

Desoto Beach Bed & Breakfast

Desoto Beach Bed & Breakfast
3.5 star property
17.7 mi from Oyster Reef
9.4 out of 10, Exceptional, (294 reviews)
"The breakfast was cooked fresh every day and served by the best inn keeper ive ever had. Rick was amazing. "
United States
Matthew
The price is £234
includes taxes & fees
11 Jun - 12 Jun
Desoto Beach Bed & Breakfast
Apartment (1 Bedroom) | Front of property

Walk to Bars & Shops: Resort Condo in Hilton Head!

Walk to Bars & Shops: Resort Condo in Hilton Head!
3.5 star property
North Forest Beach, 7.3 mi from Oyster Reef
The price is £251
includes taxes & fees
31 May - 1 Jun
Walk to Bars & Shops: Resort Condo in Hilton Head!
Meeting facility

Admiral's Inn on Tybee Island

Admiral's Inn on Tybee Island
2.5 star property
18.9 mi from Oyster Reef
8.4 out of 10, Very good, (1,001 reviews)
"A very clean hotel- good value for the money."
United States
Rebecca
The price is £125
includes taxes & fees
19 May - 20 May
Admiral's Inn on Tybee Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Oyster Reef

Find the best Oyster Reef areas for the activities you enjoy most.
Leuchtturm Hilton Head Island

Sea Pines

While visiting Sea Pines, you might make a stop by sights like Atlantic Dunes by Davis Love III and Harbour Town Golf Links.

Photo by Bill Van Cleave
Open Photo by Bill Van Cleave

South End

If you're spending some time in South End, Sea Pines Forest Preserve and Coligny Beach are top sights worth seeing.

HiltonHeadIsland_FollyFieldBeachPark_6300724_0005

Mid Island

While visiting Mid Island, you might make a stop by sights like Shelter Cove Harbour and Singleton Beach.

Photo by Greg Taylor
Open Photo by Greg Taylor

South Forest Beach

If you're spending some time in South Forest Beach, Coligny Beach and Sea Pines Forest Preserve are top sights worth seeing.

Photo by Bill Van Cleave
Open Photo by Bill Van Cleave

North Forest Beach

If you're spending some time in North Forest Beach, Coligny Plaza and Coligny Beach are top sights worth seeing.

Top Oyster Reef Hotel Reviews

Holiday Inn Express Hilton Head Island by IHG

Holiday Inn Express Hilton Head Island by IHG

6/10 Okay
"Parking fee even if you do not park in garage. Dated rooms. Could use some updates but close to the beach"
Michelle 2-night trip
Posted 4 hours ago
Holiday Inn Express Hilton Head Island by IHG

Frequently asked questions

When is the best time to go to Oyster Reef?
The best time to visit Oyster Reef is during the spring (April to May) and autumn (September to October) months. These periods offer comfortable temperatures and less humidity, making outdoor activities particularly enjoyable.

Spring in Oyster Reef brings pleasant weather, with average temperatures ranging from 18°C to 25°C. This is ideal for exploring the natural beauty of the area, such as walking along the marsh trails or enjoying a round of golf. The local flora also begins to bloom, adding to the scenic appeal.

Autumn also provides excellent conditions, with temperatures typically between 20°C and 27°C. The humidity levels drop significantly, and the waters of the Atlantic remain warm enough for swimming and watersports well into October. This season is great for those looking to experience the beaches and outdoor amenities without the peak summer crowds.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Oyster Reef.
How can I save on a Oyster Reef hotel booking with Expedia?
Members always get our best prices. Find our best Oyster Reef hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Oyster Reef hotel?
Hotel prices in Oyster Reef often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia