A large eye sculpture in a park surrounded by trees.

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Check availability on Northeast Missouri 4 Star Hotels

Tonight
16 Oct - 17 Oct
Tomorrow
17 Oct - 18 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Northeast Missouri 4-star hotels

A buffet with fruits, pastries, and beverages.
A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.
The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
United States
Anthony
£104
includes taxes & fees
15 Nov - 16 Nov
Renaissance St. Louis Airport Hotel
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
United States
Zane
£130
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
A restaurant with a central bar area, seating arrangements, and a fireplace.
A modern building with a unique, curved roof structure.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.

3. The Cheshire

The Cheshire
Richmond Heights
United States
Matthew
£132
includes taxes & fees
1 Nov - 2 Nov
The Cheshire
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.
A modern living room with a sofa, coffee table, and bookshelves.
A restaurant with tables set for dining, a kitchen in the background, and hanging light fixtures.

4. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
United States
Molly
£124
includes taxes & fees
15 Nov - 16 Nov
Live by Loews - St.Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern living room with a grey sofa, a round wooden coffee table, and a large window with a city view.
A lobby with wooden paneling, a green wall, and two armchairs.
A modern restaurant interior with high tables, chairs, and a central bar area.

5. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
United States
Stacy
£115
includes taxes & fees
15 Nov - 16 Nov
The Westin St. Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.

6. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
United States
Kristina
£165
includes taxes & fees
15 Nov - 16 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A casino with multiple blackjack tables, a chandelier, and ornate wall decorations.
A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.
A large hotel with a prominent "RIVER CITY" sign.
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

7. River City Casino & Hotel

River City Casino & Hotel
St. Louis
United States
jodi
£101
includes taxes & fees
10 Nov - 11 Nov
River City Casino & Hotel
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
A modern hotel room with a large window, a bathtub, and a unique eye-themed pillow.
A woman sitting on a green sofa in a modern lobby with a staircase and a large framed artwork on the wall.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and a series of uniformly lit windows.

8. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
United States
Skylee
£112
includes taxes & fees
25 Oct - 26 Oct
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.
A bakery display case with various pastries and cakes.

9. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
United States
Melissa
£146
includes taxes & fees
16 Nov - 17 Nov
Ameristar Casino Resort and Spa
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.
A spacious interior with a central staircase, large windows, and hanging chandeliers.
A grand hall with rows of chairs arranged for an event, a central floral arrangement, and a large chandelier.
Lobby

10. Marriott St. Louis Grand

Marriott St. Louis Grand
Downtown St. Louis
United States
Andrew
£136
includes taxes & fees
30 Oct - 31 Oct
Marriott St. Louis Grand
A rooftop restaurant with round tables, chairs, and a view of the city.
A modern lobby with a staircase, seating area, and wall-mounted artwork.
A hotel with a prominent sign reading "MOONRISE."
A modern lobby with a staircase, seating area, and an exit sign.

11. Moonrise Hotel

Moonrise Hotel
Delmar Loop
United States
Jessie
£143
includes taxes & fees
16 Nov - 17 Nov
Moonrise Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.
A spa bath with a sign indicating a capacity of 8 persons.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

12. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
United States
Janell
£114
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
An indoor swimming pool area with lounge chairs, a small table, and potted plants.
A buffet area with various food items and a self-service station.
A spacious lobby with striped chairs, a central coffee table, and large potted plants.

13. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United Kingdom
Luke
£105
includes taxes & fees
28 Oct - 29 Oct
Embassy Suites by Hilton St. Louis Downtown
A modern hotel room with a large dining table, comfortable seating, a sofa, and a television.
A modern lounge area with a central fire feature, seating, and large windows offering a city view.
A modern hotel with a prominent Hilton sign, surrounded by a spacious parking lot and a well-maintained lawn.
A modern kitchen with a central island, bar stools, and a long dining table.

14. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
Downtown St. Louis
United States
kristen
£131
includes taxes & fees
28 Oct - 29 Oct
Hilton St. Louis at the Ballpark
A brick building with a tower, large windows, and a fountain in the garden.
A grand staircase with a curved design, leading to an upper floor.
A grand lobby with a chandelier, a staircase, and a central table with a floral arrangement.
A spacious lobby with a chandelier, seating area, and a central table with a vase of flowers.

15. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
Frontenac
United States
Linda L
£114
includes taxes & fees
25 Oct - 26 Oct
Hilton St. Louis Frontenac
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
A bar area with a round table, ice-filled glasses, bottles of champagne, and decorative plants.
A long dining table set with candles, glassware, and white flowers, suggesting a formal dining experience.
An outdoor seating area with modern furniture, a metal railing, and a view of surrounding buildings.

16. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
United States
Marsha
£134
includes taxes & fees
1 Nov - 2 Nov
Le Méridien St. Louis Clayton
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.
A modern lobby with seating areas, a reception desk, and a bar area.
A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.
A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

17. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
United States
Sha
£129
includes taxes & fees
30 Oct - 31 Oct
Marriott St. Louis Airport
A bar area with a central bar, multiple stools, and a chandelier.
A grand lobby with a bar area, ornate chandeliers, and a staircase.
A spacious lobby with a high ceiling, ornate chandeliers, and a seating area with sofas and armchairs.
A grand lobby with a large chandelier, a bar area, and classical architecture.

18. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
United States
Carol
£99
includes taxes & fees
30 Oct - 31 Oct
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.
A multi-level hotel lobby with a grand staircase, a reception desk, and a seating area.
A spacious lobby with a high arched ceiling, multiple seating areas, and a central decorative column.
A restaurant with tables and chairs, large windows, and a view of the street.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
United States
Maryann
£146
includes taxes & fees
30 Oct - 31 Oct
St. Louis Union Station Hotel, Curio Collection by Hilton
A modern dining area with multiple tables and chairs, large windows with a city view, and contemporary lighting fixtures.
A hotel room with a sofa, a round table with a tray, a black dresser, and a large window with a view of a building.
A grand lobby with a high ceiling, ornate chandeliers, and a central seating area with blue upholstered chairs.
A rooftop pool area with lounge chairs and a clear view of the city skyline.

20. Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection
Downtown St. Louis
United States
Shawn
£151
includes taxes & fees
15 Nov - 16 Nov
Hotel Saint Louis, Autograph Collection
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Northeast Missouri.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
£507
1 Nov - 2 Nov
includes taxes & fees
9.2/10 Wonderful! (586 reviews)
The Ritz-Carlton, St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theatres.

See all hotels in Northeast Missouri
A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

Moonrise Hotel

Moonrise Hotel

8/10 Good
"Really cute hotel in Delmar Loop. Fun, quirky style. Excellent location, but our room smelled like wet dog."
Elina 1-night trip
Posted 4 hours ago
Moonrise Hotel
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"Parking easy and gated, a little expensive but convenient. Two entrances, easy access to Grand for The Fox or symphony. Elevators were a little confusing at first. Roof Top bar was great. We did not get food but a lot of people did. Beautiful city view day and night. Lots of beautiful, interesting art. I was looking forward to the matching bedding and Eye pillows but they were not there...."
Laura 1-night trip
Posted 10 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Staff were very helpful and friendly.."
shelley 1-night trip
Posted 1 day ago
Live by Loews - St.Louis

Find out more about Northeast Missouri

Frequently asked questions

What are the best 4-star hotels in Northeast Missouri?
You can find a variety of 4-star hotels in Northeast Missouri, including in St. Louis. St. Louis Union Station Hotel, Curio Collection by Hilton is an Expedia customer favourite here that offers premium bedding and concierge services. Another place that rates highly with travellers is The Last Hotel. Concierge services and a pillowtop mattress help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Northeast Missouri?
We can help you quickly locate the ideal 4-star hotel for your trip to Northeast Missouri. Use our filter tool to fine-tune your search by things like amenities, budget and star rating and get access to unbeatable deals in a couple of clicks.
  • Search for the lowest price from £507
What's the difference between 5-star and 4-star hotels in Northeast Missouri?
Give yourself the luxury treatment during your Northeast Missouri escape by checking in to a 4-star hotel. As well as featuring upscale accommodation, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and unforgettable one. 24-hour front desk, luxurious spas and world-class dining are only the start of the exclusive services and conveniences you'll likely be able to enjoy.

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