A sunset over a beach with a pier and people walking on the sand.

Southwest Coast Florida Adventure Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Top Adventure holiday packages in Southwest Coast Florida

Price found within the past 48 hours. Click for updated prices.
  • 21 Sept - 27 Sept

    Marriott Sanibel Harbour Resort & Spa + Flight

    Punta Rassa
    6 nights
    4.0 star property
    8.6/10 - Excellent (1,001 reviews)
    "Loved our view of the Harbour. Close to Sanibel Island. Lots to see and do. Pools were great too!"
    Reviewed July 31, 2026
    Return London (LON) - Fort Myers (RSW)
    LHR - MIADirect MIA - LHR1 stop
    £1,154
    £911
    per traveller
    found 1 day ago
    Marriott Sanibel Harbour Resort & Spa
  • 6 Sept - 9 Sept

    Lani Kai Beachfront Resort + Flight

    Fort Myers Beach
    3 nights
    3.5 star property
    8.8/10 - Excellent (1,835 reviews)
    "The proximity to where the pier used to be and restaurants was great. Property has a great old Florida feel. The room was very clean. The pool was small and crowded. It would be helpful to have an outdoor rinse station when coming off of the beach. You also had to pay for the beach chairs and umbrella which I wasn’t expecting. Wonderful spot especially for the price. Will defy go again!!!!!"
    Reviewed July 31, 2026
    Return Manchester (MAN) - Fort Myers (RSW)
    MAN - MIA2 stops MIA - MAN1 stop
    £2,158
    £1,672
    per traveller
    found 13 hours ago
    Lani Kai Beachfront Resort
  • 6 Sept - 9 Sept

    La Quinta Inn & Suites by Wyndham Naples Downtown + Flight

    East Naples
    3 nights
    3.0 star property
    8.2/10 - Very good (2,062 reviews)
    "Excelente lo recomiendo mucho l personal muy amable"
    Reviewed July 28, 2026
    Return Manchester (MAN) - Fort Myers (RSW)
    MAN - MIA2 stops MIA - MAN1 stop
    £2,014
    £1,569
    per traveller
    found 13 hours ago
    La Quinta Inn & Suites by Wyndham Naples Downtown

Discover the most popular places to visit in Southwest Coast Florida

Top Adventure Southwest Coast Florida Hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find awesome Southwest Coast Florida adventure vacations

How can I book the best Southwest Coast Florida adventure trips?

Choose your own adventure in Southwest Coast Florida, whether that’s a white-knuckle experience or a weekend walk. Read the reviews of the adventures that have gone before to be sure your chosen stay is your idea of fun.

How can I plan the perfect Southwest Coast Florida family adventure vacation?

Adventure awaits when you select the family-friendly filter. There’s plenty of excitement for all ages in Southwest Coast Florida. Just make sure to check your chosen escapade is within the realms of can-do for the whole clan and will have the whole team grinning.

Can I book all-inclusive Southwest Coast Florida adventure vacation packages?

By refining your filters, you can explore all-amazing, all-adventurous, all-inclusive vacation packages. Amp up the extravagance with a few more filters too. Pick pristine pools, sensational spas, or wondrous waterparks for a sensational adventure getaway.

Why should I book a Southwest Coast Florida adventure vacation for couples?

Book a Southwest Coast Florida couples adventure vacation for the ultimate in romance and memory-making. Stunning scenery, heart-racing happenings, and the grandeur of the great outdoors—it’s the best way to bond.

How can I find the best deals on adventure packages in Southwest Coast Florida?

It’s easy to unleash fabulously affordable adventures. Enter the dates for your caper, then sort your search results by price or deals.

Can I book an adventure vacation package in Southwest Coast Florida with free cancellation and/or flexible dates?

Yes! When you’re searching for a great getaway, filter by payment option for free cancellation, so a change of plans won’t mess up your adventures. You’ll find buy now, pay later options, too, for full-on flexibility.

Why should I book a Southwest Coast Florida adventure trip with Expedia?

Adventure, airfare, accommodation, ATOL protection, and activities—all on one site. And that’s just the benefits that begin with A.

What types of mountain accommodations are available in Southwest Coast Florida?

5-star hotels, cozy mountain lodges, and quaint bed and breakfasts are some of the most popular types of mountain accommodations for your vacation to Southwest Coast Florida. Don't forget to use the filters to home in the amenities you'd like to have, too. Maybe it's a spacious suite with a mountain view or a traditional lobby with a fireplace—you'll find it all with Expedia's easy-to-use search wizard and wide choice of accommodation.