Title: Panama Adults Only Holidays 2025/2026 | Expedia.co.uk ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Panama Adults Only Holidays ## Book a Adults Only Hotel + Flight or Car together to unlock savings Photo by PhotoJoy - ## Plan, book, travel with confidence ### Better together Save up to £335 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Packages with flights are ATOL protected ## 4 Night Adults Only holidays in Panama Price found within the past 48 hours. Click for updated prices. ![Tantalo Hotel](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/255ee499_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Tantalo Hotel Casco Viejo £1,789 per person 31 Dec - 3 Jan found 1 day ago Return direct flight included Argyle (SVD) to Panama City (PTY) 8.8/10 Excellent! (272 reviews) Right where you want to. In the middle of tons of shops, restaurants and town square. Rooftop bar a must for cocktails and view. Room was so spacious and comfortable. 10 out of 10. Reviewed on 19 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-31/2026-01-03/?FromAirport=SVD&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=4880470&paandie=true&dealMarker=gFDIYQSRJeHV2svAQJ0UXpgKxq2CHy8TbT9_yolWyDkseqzIJlAeSDi_j5xBQyHT) Don't see what you're looking for? See all available trips from Argyle to Panama [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2025-11-07/2025-11-14/?FromAirport=SVD&Destination=PAN&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Top Adults Only Panama Hotels ![Tantalo Hotel](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/255ee499_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Tantalo Hotel Calle 8 Este con Avenida B, Casco Viejo, San Felipe, Ciudad de Panama, Panama City, Panama - 4 min drive from Albrook Shopping Mall Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff ... 8.6/10 Excellent! (273 reviews) "Right where you want to. In the middle of tons of shops, restaurants and town square. Rooftop bar a must for cocktails and view. Room was so spacious and comfortable. 10 out of 10." Reviewed on 19 Sept 2025 [Get rates](https://expedia.co.uk/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) [](https://expedia.co.uk/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) ![The Haven and Spa - Health and Wellness Accommodation - Adults Only](https://images.trvl-media.com/lodging/5000000/4070000/4061500/4061472/97f64142_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Haven and Spa - Health and Wellness Accommodation - Adults Only Avenida A Oeste, Bajo, Boquete, Chiriqui - 7 hours drive from Albrook Shopping Mall Stay at this 3.5-star spa hotel in Boquete. Enjoy free Wi-Fi, free parking and a full-service spa. Popular attractions Boquete Library and Municipal Park are ... "Definitely a mountaintop heaven." Reviewed on 25 Feb 2022 [Get rates](https://expedia.co.uk/Boquete-Hotels-The-Haven-And-Spa-Health-And-Wellness-Accommodation-Adults-Only.h4061472.Hotel-Information) [](https://expedia.co.uk/Boquete-Hotels-The-Haven-And-Spa-Health-And-Wellness-Accommodation-Adults-Only.h4061472.Hotel-Information) [See all 3,329 properties in Panama](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=142) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More holidays you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holiday packages](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## More Holiday Ideas [Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Panama Holiday Rentals](https://expedia.co.uk/Destinations-In-Panama.d142.Holiday-Rental-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks)[Things to do in Panama](https://expedia.co.uk/Things-To-Do-In-Panama.d142.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)