Title: Cheap Flights from Milan to São Tomé Island (MXP to TMS) - Expedia.co.uk ![Adobe](https://images.trvl-media.com/place/3486/703f69b0-0f4e-4999-b953-08659a8d079c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3486/703f69b0-0f4e-4999-b953-08659a8d079c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Milan (MXP) to São Tomé Island (TMS) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Malpensa International Airport (MXP) to São Tomé Island (TMS-São Tomé Intl.) - ![Turkish Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TK.svg) Turkish Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:MXP,to:TMS,departure:05/12/2025TANYT&leg2=from:TMS,to:MXP,departure:12/12/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TK"}}]) - ![TAP Portugal](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg) TAP Portugal [](https://www.expedia.co.uk/Flights-Search?leg1=from:MXP,to:TMS,departure:05/12/2025TANYT&leg2=from:TMS,to:MXP,departure:12/12/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TP"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Milan (MXP) to São Tomé Island (TMS) Prices were available within the past 7 days and start at for one-way flights and £958 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 7 Feb - Sun, 15 Feb MXP Milan TMS São Tomé Island £958 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MXP,to:TMS,departure:07/02/2026TANYT&leg2=from:TMS,to:MXP,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:957.20&airProductToken=AQpuCjQI1KABEgM4MjcY7H0gi5IBKO3EhAMwnMaEAzhFQABYAWoIRElTQ09VTlRyCEVMMERTSTgxCjYI1KABEgQxNTI3GIuSASCTkwEo38yEAzDd0IQDOEVAAVgBaghESVNDT1VOVHIIRUwwRFNJODEKbgo2CNSgARIEMTUyOBiTkwEgi5IBKLCghQMw0aSFAzhMQABYAWoIRElTQ09VTlRyCExMMERTSTcxCjQI1KABEgM4MjgYi5IBIOx9KMarhQMw66yFAzhMQAFYAWoIRElTQ09VTlRyCExMMERTSTcxEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ) ![Turkish Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TK.gif) Sat, 7 Feb - Sun, 15 Feb MXP Milan TMS São Tomé Island £993 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MXP,to:TMS,departure:07/02/2026TANYT&leg2=from:TMS,to:MXP,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:993.00&airProductToken=AQqnAQotCNSWARIEMTg5NhjsfSDInAEoqsOEAzDexIQDOFdAAFgBagJQU3IGV04zWFBDCi4I1JYBEgQxNzc5GMicASCLkgEos8WEAzDpx4QDOFdAAVgBagJQU3IGV04zWFBDCkYI1JYBEgQ4ODE1GIuSASCTkwEo38yEAzDd0IQDOFdAAVgBagJQU3IGV04zWFBDegoI1KABEgQ4ODE1egoI1KABEgQ4ODE1CqcBCkYI1JYBEgQ4ODE2GJOTASCLkgEosKCFAzDRpIUDOFdAAFgBagJQU3IGV04zWFBDegoI1KABEgQ4ODE2egoI1KABEgQ4ODE2Ci4I1JYBEgQxNzYwGIuSASDInAEo5amFAzCHrIUDOFdAAVgBagJQU3IGV04zWFBDCi0I1JYBEgQxODczGMicASDsfSiZsIUDMMixhQM4V0ABWAFqAlBTcgZXTjNYUEMSCggBEAEYASoCVEsYASIECAEQASgCKAMoBDAB) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 7 Feb - Sun, 15 Feb MXP Milan TMS São Tomé Island £1,003 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MXP,to:TMS,departure:07/02/2026TANYT&leg2=from:TMS,to:MXP,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1002.10&airProductToken=AQpsCjMI1KABEgM4MjcY7H0gi5IBKO3EhAMwnMaEAzhFQABYAWoHRElTQ0lOVHIIRUwwRFNJODEKNQjUoAESBDE1MjcYi5IBIJOTASjfzIQDMN3QhAM4RUAAWAFqB0RJU0NJTlRyCEVMMERTSTgxCmwKNQjUoAESBDE1MjgYk5MBIIuSASiwoIUDMNGkhQM4S0AAWAFqB0RJU0NJTlRyCEtMMERTSTcxCjMI1KABEgM4MjYYi5IBIOx9KLaohQMw26mFAzhLQABYAWoHRElTQ0lOVHIIS0wwRFNJNzESCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 7 Feb - Sun, 15 Feb MXP Milan TMS São Tomé Island £1,008 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MXP,to:TMS,departure:07/02/2026TANYT&leg2=from:TMS,to:MXP,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1007.60&airProductToken=AQpsCjMI1KABEgM4MjMY7H0gi5IBKI_ChAMww8OEAzhFQABYAWoHRElTQ0lOVHIIRUwwRFNJODEKNQjUoAESBDE1MjcYi5IBIJOTASjfzIQDMN3QhAM4RUAAWAFqB0RJU0NJTlRyCEVMMERTSTgxCmwKNQjUoAESBDE1MjgYk5MBIIuSASiwoIUDMNGkhQM4S0AAWAFqB0RJU0NJTlRyCEtMMERTSTcxCjMI1KABEgM4MjYYi5IBIOx9KLaohQMw26mFAzhLQABYAWoHRElTQ0lOVHIIS0wwRFNJNzESCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 7 Feb - Sun, 15 Feb MXP Milan TMS São Tomé Island £1,178 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MXP,to:TMS,departure:07/02/2026TANYT&leg2=from:TMS,to:MXP,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1177.50&airProductToken=AQpsCjMI1KABEgM4MjkY7H0gi5IBKMC_hAMw9MCEAzhXQABYAWoHRElTQ0lOVHIIV0wwRFNJMDEKNQjUoAESBDE1MzEYi5IBIJOTASiKwoQDMJrFhAM4V0AAWAFqB0RJU0NJTlRyCFdMMERTSTAxCmwKNQjUoAESBDE1MjgYk5MBIIuSASiwoIUDMNGkhQM4TEAAWAFqB0RJU0NJTlRyCExMMERTSTcxCjMI1KABEgM4MjIYi5IBIOx9KNilhQMw_aaFAzhMQABYAWoHRElTQ0lOVHIITEwwRFNJNzESCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Sat, 7 Feb - Sun, 15 Feb MXP Milan TMS São Tomé Island £1,224 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:MXP,to:TMS,departure:07/02/2026TANYT&leg2=from:TMS,to:MXP,departure:15/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1223.40&airProductToken=AQpsCjMI1KABEgM4MjkY7H0gi5IBKMC_hAMw9MCEAzhXQABYAWoHRElTQ0lOVHIIV0wwRFNJMDEKNQjUoAESBDE1MzEYi5IBIJOTASiKwoQDMJrFhAM4V0AAWAFqB0RJU0NJTlRyCFdMMERTSTAxCmwKNQjUoAESBDE1MjgYk5MBIIuSASiwoIUDMNGkhQM4S0AAWAFqB0RJU0NJTlRyCEtMMERTSTcxCjMI1KABEgM4MjYYi5IBIOx9KLaohQMw26mFAzhLQABYAWoHRElTQ0lOVHIIS0wwRFNJNzESCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=FTG_BF_PROMO_) Flight from Milan to São Tomé Island route information | Origin airport | Malpensa Intl. | | --- | --- | | Destination airport | São Tomé Intl. | | Return price | £957 | | Distance | 5006 km | ## Compare flights from Milan to São Tomé Island easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Milan to São Tomé Island. Operating between them flights per day, 6 airlines cover the route. And fly direct, getting you to São Tomé Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Malpensa Intl. to São Tomé Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Malpensa Intl. (MXP) to São Tomé Intl. (TMS) The easiest way to view the best deals on flights from Milan to São Tomé Island today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Malpensa Intl. to São Tomé Intl. start at just £958 and range up to £1,224.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Milan and São Tomé Island - booking your flight during February, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Milan to São Tomé Island flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Malpensa Intl. to São Tomé Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Accommodation ### Accommodation - [Água Grande Hotels](https://www.expedia.co.uk/Destinations-In-Agua-Grande.d553248635976006815.Hotel-Destinations) - [Hotels near Estadio Nacional 12 de Julho](https://www.expedia.co.uk/Estadio-Nacional-12-De-Julho-Hotels.0-l6118168-0.Travel-Guide-Filter-Hotels) - [São Tomé Hotels](https://www.expedia.co.uk/Sao-Tome-Hotels.d553248635975177343.Travel-Guide-Hotels) \*Available to Expedia members.