Title: £809 Cheap Flights from Frankfurt to São Tomé Island (FRA to TMS) - Expedia.co.uk ![A pretty sunset in São Tomé.](https://images.trvl-media.com/place/553248635976006815/07aca925-8318-4676-9191-b2ca4e7702d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Toshiaki Yoshitake ![](https://images.trvl-media.com/place/553248635976006815/07aca925-8318-4676-9191-b2ca4e7702d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £809 Cheap Flights from Frankfurt (FRA) to São Tomé Island (TMS) [View £809 flight on Thu, 18 Sept 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:FRA,to:TMS,departure:18/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:808.50&airProductToken=AQpsCjMI1KABEgM1NzEYpQQgi5IBKPKE-AIwtYb4AjhXQABYAWoHRElTQ0lOVHIIV0wwRFNJMDUKNQjUoAESBDE1MjcYi5IBIJOTASj3jvgCMP-S-AI4V0AAWAFqB0RJU0NJTlRyCFdMMERTSTA1EgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwDQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Frankfurt Airport (FRA) to São Tomé Island (TMS-São Tomé Intl.) - ![TAP Portugal](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg) TAP Portugal [](https://www.expedia.co.uk/Flights-Search?leg1=from:fra,to:tms,departure:01/10/2025TANYT&leg2=from:tms,to:fra,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TP"}}]) - ![Ethiopian Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_ET.svg) Ethiopian Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:fra,to:tms,departure:01/10/2025TANYT&leg2=from:tms,to:fra,departure:08/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"ET"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Frankfurt (FRA) to São Tomé Island (TMS) Prices were available within the past 7 days and start at £809 for one-way flights and £1,323 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,323 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1322.90&airProductToken=AQqiAQozCNSgARIENjY4NBilBCDucyi88IIDMOHxggM4QUAAWAFqB0RJU0NJTlRyCEFMMEJTSTAxCjQI1KABEgQxOTI5GO5zIIuSASiI-YIDMMT5ggM4QUAAWAFqB0RJU0NJTlRyCEFMMEJTSTAxCjUI1KABEgQxNTI3GIuSASCTkwEon4KDAzCdhoMDOEFAAFgBagdESVNDSU5UcghBTDBCU0kwMQpsCjUI1KABEgQxNTMyGJOTASCLkgEo4fiDAzDx-4MDOFdAAFgBagdESVNDSU5UcghXTDBEU0kwMQozCNSgARIDNTcwGIuSASClBCi0_YMDMPL-gwM4V0AAWAFqB0RJU0NJTlRyCFdMMERTSTAxEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwDQ) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 18 Sept - Fri, 26 Sept FRA Frankfurt TMS São Tomé Island £1,335 Return found 1 hour ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:18/09/2025TANYT&leg2=from:TMS,to:FRA,departure:26/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1334.50&airProductToken=AQpsCjMI1KABEgM1NzEYpQQgi5IBKPKE-AIwtYb4AjhXQABYAWoHRElTQ0lOVHIIV0wwRFNJMDEKNQjUoAESBDE1MjcYi5IBIJOTASj3jvgCMP-S-AI4V0AAWAFqB0RJU0NJTlRyCFdMMERTSTAxCmwKNQjUoAESBDE1MjgYk5MBIIuSASjc4vgCMOTm-AI4V0AAWAFqB0RJU0NJTlRyCFdMMERTSTAxCjMI1KABEgM1NzAYi5IBIKUEKKfo-AIw4On4AjhXQABYAWoHRElTQ0lOVHIIV0wwRFNJMDESCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,353 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1352.80&airProductToken=AQqfAQoyCNSgARIENjY4NBilBCDucyi88IIDMOHxggM4QUAAWAFqBkJBU0lOVHIIQUwwQlNJMDEKMwjUoAESBDE5MjkY7nMgi5IBKIj5ggMwxPmCAzhBQABYAWoGQkFTSU5UcghBTDBCU0kwMQo0CNSgARIEMTUyNxiLkgEgk5MBKJ-CgwMwnYaDAzhBQABYAWoGQkFTSU5UcghBTDBCU0kwMQprCjQI1KABEgQxNTMyGJOTASCLkgEo4fiDAzDx-4MDOFdAAFgBagZCQVNJTlRyCFdMMEJTSTAxCjMI1KABEgQ2NzAzGIuSASClBCj7gIQDMLSChAM4V0AAWAFqBkJBU0lOVHIIV0wwQlNJMDESCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,355 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1354.50&airProductToken=AQqfAQoyCNSgARIENjY4NBilBCDucyi88IIDMOHxggM4QUAAWAFqBkJBU0lOVHIIQUwwQlNJMDEKMwjUoAESBDE5MjkY7nMgi5IBKIj5ggMwxPmCAzhBQABYAWoGQkFTSU5UcghBTDBCU0kwMQo0CNSgARIEMTUyNxiLkgEgk5MBKJ-CgwMwnYaDAzhBQABYAWoGQkFTSU5UcghBTDBCU0kwMQpqCjQI1KABEgQxNTMyGJOTASCLkgEo4fiDAzDx-4MDOFdAAFgBagZCQVNJTlRyCFdMMEJTSTAxCjII1KABEgM1NzAYi5IBIKUEKLT9gwMw8v6DAzhXQABYAWoGQkFTSU5UcghXTDBCU0kwMRIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,391 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1390.20&airProductToken=AQqiAQozCMyQARIDMTk2GKUEIIGJASjJ74IDMIrwggM4VEAAWAFqB0NMQVNTSUNyCExMMENMSTcxCjQI1KABEgM1MzMYgYkBIIuSASiK-oIDMPD7ggM4TEABWAFqB0NMQVNTSUNyCExMMENMSTcxCjUI1KABEgQxNTI3GIuSASCTkwEon4KDAzCdhoMDOExAAVgBagdDTEFTU0lDcghMTDBDTEk3MQpsCjUI1KABEgQxNTMyGJOTASCLkgEo4fiDAzDx-4MDOFdAAFgBagdDTEFTU0lDcghXTDBDTEkwMQozCNSgARIDNTcwGIuSASClBCi0_YMDMPL-gwM4V0ABWAFqB0NMQVNTSUNyCFdMMENMSTAxEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ) ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,393 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1392.50&airProductToken=AQqfAQoxCMyQARICMjIYpQQgh2AopO6CAzDl7oIDOFRAAFgBagdDTEFTU0lDcghMTDBDTEk3MQozCNSgARIDNTYzGIdgIIuSASiA-oIDMNf7ggM4TEABWAFqB0NMQVNTSUNyCExMMENMSTcxCjUI1KABEgQxNTI3GIuSASCTkwEon4KDAzCdhoMDOExAAVgBagdDTEFTU0lDcghMTDBDTEk3MQpsCjUI1KABEgQxNTMyGJOTASCLkgEo4fiDAzDx-4MDOFdAAFgBagdDTEFTU0lDcghXTDBDTEkwMQozCNSgARIDNTc0GIuSASClBCiWgoQDMNSDhAM4V0ABWAFqB0NMQVNTSUNyCFdMMENMSTAxEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 18 Sept - Fri, 26 Sept FRA Frankfurt TMS São Tomé Island £1,396 Return found 1 hour ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:18/09/2025TANYT&leg2=from:TMS,to:FRA,departure:26/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1395.70&airProductToken=AQpqCjII1KABEgM1NzEYpQQgi5IBKPKE-AIwtYb4AjhXQABYAWoGQkFTSU5UcghXTDBCU0kwMQo0CNSgARIEMTUyNxiLkgEgk5MBKPeO-AIw_5L4AjhXQABYAWoGQkFTSU5UcghXTDBCU0kwMQpqCjQI1KABEgQxNTI4GJOTASCLkgEo3OL4AjDk5vgCOFdAAFgBagZCQVNJTlRyCFdMMEJTSTAxCjII1KABEgM1NzAYi5IBIKUEKKfo-AIw4On4AjhXQABYAWoGQkFTSU5UcghXTDBCU0kwMRIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,398 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1397.60&airProductToken=AQqgAQoyCMyQARIDMTE2GKUEIIwVKKvvggMw4u-CAzhUQABYAWoHQ0xBU1NJQ3IITEwwQ0xJNzEKMwjUoAESAzU1NRiMFSCLkgEonvqCAzDr-4IDOExAAVgBagdDTEFTU0lDcghMTDBDTEk3MQo1CNSgARIEMTUyNxiLkgEgk5MBKJ-CgwMwnYaDAzhMQAFYAWoHQ0xBU1NJQ3IITEwwQ0xJNzEKbAo1CNSgARIEMTUzMhiTkwEgi5IBKOH4gwMw8fuDAzhXQABYAWoHQ0xBU1NJQ3IIV0wwQ0xJMDEKMwjUoAESAzU3MBiLkgEgpQQotP2DAzDy_oMDOFdAAVgBagdDTEFTU0lDcghXTDBDTEkwMRIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMAE) ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,401 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1400.10&airProductToken=AQqhAQoyCMyQARICODgYpQQgg5UBKOTwggMwkfGCAzhUQABYAWoHQ0xBU1NJQ3IITEwwQ0xJNzEKNAjUoAESAzU0MxiDlQEgi5IBKJ76ggMw1_uCAzhMQAFYAWoHQ0xBU1NJQ3IITEwwQ0xJNzEKNQjUoAESBDE1MjcYi5IBIJOTASifgoMDMJ2GgwM4TEABWAFqB0NMQVNTSUNyCExMMENMSTcxCmwKNQjUoAESBDE1MzIYk5MBIIuSASjh-IMDMPH7gwM4V0AAWAFqB0NMQVNTSUNyCFdMMENMSTAxCjMI1KABEgM1NzQYi5IBIKUEKJaChAMw1IOEAzhXQAFYAWoHQ0xBU1NJQ3IIV0wwQ0xJMDESCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAB) ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,403 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1403.00&airProductToken=AQqgAQoyCMyQARIDMTE4GKUEIIwVKOfvggMwnvCCAzhUQABYAWoHQ0xBU1NJQ3IITEwwQ0xJNzEKMwjUoAESAzU1MxiMFSCLkgEohviCAzDT-YIDOExAAVgBagdDTEFTU0lDcghMTDBDTEk3MQo1CNSgARIEMTUyNxiLkgEgk5MBKJ-CgwMwnYaDAzhMQAFYAWoHQ0xBU1NJQ3IITEwwQ0xJNzEKbAo1CNSgARIEMTUzMhiTkwEgi5IBKOH4gwMw8fuDAzhXQABYAWoHQ0xBU1NJQ3IIV0wwQ0xJMDEKMwjUoAESAzU3NBiLkgEgpQQoloKEAzDUg4QDOFdAAVgBagdDTEFTU0lDcghXTDBDTEkwMRIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMAE) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Mon, 19 Jan - Sat, 31 Jan FRA Frankfurt TMS São Tomé Island £1,426 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:FRA,to:TMS,departure:19/01/2026TANYT&leg2=from:TMS,to:FRA,departure:31/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1425.50&airProductToken=AQqfAQoyCNSgARIENjY4NBilBCDucyi88IIDMOHxggM4QUAAWAFqBkJBU0lOVHIIQUwwQlNJMDEKMwjUoAESBDE5MjEY7nMgi5IBKNz2ggMwmPeCAzhBQABYAWoGQkFTSU5UcghBTDBCU0kwMQo0CNSgARIEMTUyNxiLkgEgk5MBKJ-CgwMwnYaDAzhBQABYAWoGQkFTSU5UcghBTDBCU0kwMQqfAQo0CNSgARIEMTUzMhiTkwEgi5IBKOH4gwMw8fuDAzhWQABYAWoGQkFTSU5UcghWTDBCU0kwMQozCNSgARIEMTkyNBiLkgEg7nMonf6DAzDU_oMDOFZAAFgBagZCQVNJTlRyCFZMMEJTSTAxCjII1KABEgQ2NjgxGO5zIKUEKK7_gwMw04CEAzhWQABYAWoGQkFTSU5UcghWTDBCU0kwMRIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) Flight from Frankfurt to São Tomé Island route information | Origin airport | Frankfurt Intl. | | --- | --- | | Destination airport | São Tomé Intl. | | Return price | £1,323 | | Distance | 5494 km | ## Compare flights from Frankfurt to São Tomé Island easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Frankfurt to São Tomé Island. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to São Tomé Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Frankfurt Intl. to São Tomé Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Frankfurt Intl. (FRA) to São Tomé Intl. (TMS) The easiest way to view the best deals on flights from Frankfurt to São Tomé Island today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Frankfurt Intl. to São Tomé Intl. start at just £1,323 and range up to £1,426.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Frankfurt and São Tomé Island - booking your flight during January, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Frankfurt to São Tomé Island flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Frankfurt Intl. to São Tomé Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Trending Routes - Trending Flights - Top Flights Destinations - Related Airlines - Cheap Flights from Other Airports - Expedia's Latest Trends ### Top Routes from Frankfurt - [Frankfurt to Mumbai (FRA - BOM)](https://expedia.co.uk/lp/flights/fra/bom/frankfurt-to-mumbai) - [Frankfurt to Newark Liberty Intl. Airport (FRA - EWR)](https://expedia.co.uk/lp/flights/fra/ewr/frankfurt-to-newark-liberty-intl-airport) - [Frankfurt to Auckland (FRA - AKL)](https://expedia.co.uk/lp/flights/fra/akl/frankfurt-to-auckland) - [Frankfurt to London (FRA - LCY)](https://expedia.co.uk/lp/flights/fra/lcy/frankfurt-to-london) - [Frankfurt to Bangkok (FRA - BKK)](https://expedia.co.uk/lp/flights/fra/bkk/frankfurt-to-bangkok) - [Frankfurt to Paris (FRA - CDG)](https://expedia.co.uk/lp/flights/fra/cdg/frankfurt-to-paris) - [Frankfurt to Delhi (FRA - DEL)](https://expedia.co.uk/lp/flights/fra/del/frankfurt-to-delhi) - [Frankfurt to New York (FRA - JFK)](https://expedia.co.uk/lp/flights/fra/jfk/frankfurt-to-new-york) - [Frankfurt to Dublin (FRA - DUB)](https://expedia.co.uk/lp/flights/fra/dub/frankfurt-to-dublin) - [Frankfurt to Tokyo (FRA - NRT)](https://expedia.co.uk/lp/flights/fra/nrt/frankfurt-to-tokyo) - [Frankfurt to Birmingham (FRA - BHX)](https://expedia.co.uk/lp/flights/fra/bhx/frankfurt-to-birmingham) - [Frankfurt to Seoul (FRA - ICN)](https://expedia.co.uk/lp/flights/fra/icn/frankfurt-to-seoul) ### Top Routes to São Tomé Island - [Accra to São Tomé Island (ACC - TMS)](https://expedia.co.uk/lp/flights/acc/tms/accra-to-sao-tome-island) - [Libreville to São Tomé Island (LBV - TMS)](https://expedia.co.uk/lp/flights/lbv/tms/libreville-to-sao-tome-island) - [Brussels to São Tomé Island (BRU - TMS)](https://expedia.co.uk/lp/flights/bru/tms/brussels-to-sao-tome-island) - [Prague to São Tomé Island (PRG - TMS)](https://expedia.co.uk/lp/flights/prg/tms/prague-to-sao-tome-island) - [Lisbon to São Tomé Island (LIS - TMS)](https://expedia.co.uk/lp/flights/lis/tms/lisbon-to-sao-tome-island) - [London to São Tomé Island (LHR - TMS)](https://expedia.co.uk/lp/flights/lhr/tms/london-to-sao-tome-island) - [Manchester to São Tomé Island (MAN - TMS)](https://expedia.co.uk/lp/flights/man/tms/manchester-to-sao-tome-island) - [São Paulo to São Tomé Island (GRU - TMS)](https://expedia.co.uk/lp/flights/gru/tms/sao-paulo-to-sao-tome-island) - [London to São Tomé Island (LGW - TMS)](https://expedia.co.uk/lp/flights/lgw/tms/london-to-sao-tome-island) - [Luanda to São Tomé Island (LAD - TMS)](https://expedia.co.uk/lp/flights/lad/tms/luanda-to-sao-tome-island) - [Porto to São Tomé Island (OPO - TMS)](https://expedia.co.uk/lp/flights/opo/tms/porto-to-sao-tome-island) ### Top Routes from Frankfurt - [British Airways Frankfurt to London](https://expedia.co.uk/lp/flight-routes/british-airways-from-frankfurt-intl-to-london-city/ba/fra/lcy) - [British Airways Frankfurt to London](https://expedia.co.uk/lp/flight-routes/british-airways-from-frankfurt-intl-to-heathrow/ba/fra/lhr) ### Top Routes to São Tomé Island - [TAP Portugal São Paulo to São Tomé Island](https://expedia.co.uk/lp/flight-routes/tap-portugal-from-guarulhos-governor-andre-franco-montoro-intl-to-sao-tome-intl/tp/gru/tms) ### Top Flight Destinations - [Flights to Príncipe Island](https://expedia.co.uk/Cheap-Flights-To-Principe-Island.d2752.Travel-Guide-Flights) ### Related Airlines - [British Airways](https://expedia.co.uk/British-Airways-Flights.cBA.Travel-Guide-Airlines) - [KLM](https://expedia.co.uk/KLM-Flights.cKL.Travel-Guide-Airlines) - [Lufthansa](https://expedia.co.uk/Lufthansa-Flights.cLH.Travel-Guide-Airlines) - [Air France](https://expedia.co.uk/Air-France-Flights.cAF.Travel-Guide-Airlines) - [Swiss International Air Lines](https://expedia.co.uk/Swiss-International-Air-Lines-Flights.cLX.Travel-Guide-Airlines) - [SAS](https://expedia.co.uk/Scandinavian-Airlines-Flights.cSK.Travel-Guide-Airlines) - [Aer Lingus](https://expedia.co.uk/Aer-Lingus-Flights.cEI.Travel-Guide-Airlines) - [Brussels Airlines](https://expedia.co.uk/Brussels-Airlines-Flights.cSN.Travel-Guide-Airlines) - [Austrian Airlines](https://expedia.co.uk/Austrian-Airlines-Flights.cOS.Travel-Guide-Airlines) - [ITA Airways](https://expedia.co.uk/ITA-Airways-Flights.cAZ.Travel-Guide-Airlines) - [Turkish Airlines](https://expedia.co.uk/Turkish-Airlines-Flights.cTK.Travel-Guide-Airlines) - [Iberia](https://expedia.co.uk/Iberia-Flights.cIB.Travel-Guide-Airlines) - [LOT-Polish Airlines](https://expedia.co.uk/LOT-Polish-Airlines-Flights.cLO.Travel-Guide-Airlines) - [Qatar Airways](https://expedia.co.uk/Qatar-Airways-Flights.cQR.Travel-Guide-Airlines) - [Emirates](https://expedia.co.uk/Emirates-Flights.cEK.Travel-Guide-Airlines) - [Etihad Airways](https://expedia.co.uk/Etihad-Airways-Flights.cEY.Travel-Guide-Airlines) ### Nearby Airports - [Mainz Finthen Airport (QFZ)](https://expedia.co.uk/lp/airports/qfz/flights-from-mainz-finthen-airport) - [Mannheim Airport (MHG)](https://expedia.co.uk/lp/airports/mhg/flights-from-mannheim-airport) - [Frankfurt - Hahn Airport (HHN)](https://expedia.co.uk/lp/airports/hhn/flights-from-frankfurt-hahn-airport) - [Cologne - Bonn Airport (CGN)](https://expedia.co.uk/lp/airports/cgn/flights-from-cologne-bonn-airport) - [Saarbruecken Airport (SCN)](https://expedia.co.uk/lp/airports/scn/flights-from-saarbruecken-airport) - [Baden Airpark Airport (FKB)](https://expedia.co.uk/lp/airports/fkb/flights-from-baden-airpark-airport) - [Stuttgart Airport (STR)](https://expedia.co.uk/lp/airports/str/flights-from-stuttgart-airport) - [Paderborn - Lippstadt Airport (PAD)](https://expedia.co.uk/lp/airports/pad/flights-from-paderborn-lippstadt-airport) - [Dortmund Airport (DTM)](https://expedia.co.uk/lp/airports/dtm/flights-from-dortmund-airport) - [Düsseldorf Intl. Airport (DUS)](https://expedia.co.uk/lp/airports/dus/flights-from-dusseldorf-intl-airport) ### Expedia's Latest Trends Flights - [Flights from London to Nuremberg](https://expedia.co.uk/lp/flights/lhr/nue/london-to-nuremberg) - [Flights from Bristol to Munich](https://expedia.co.uk/lp/flights/brs/muc/bristol-to-munich) - [Flights from Manchester to Hamburg](https://expedia.co.uk/lp/flights/man/ham/manchester-to-hamburg) - [Flights from London to Hamburg](https://expedia.co.uk/lp/flights/lhr/ham/london-to-hamburg) - [Flights from Manchester to Düsseldorf](https://expedia.co.uk/lp/flights/man/dus/manchester-to-dusseldorf) - [Flights from Birmingham to Düsseldorf](https://expedia.co.uk/lp/flights/bhx/dus/birmingham-to-dusseldorf) - [Flights from Munich to London](https://expedia.co.uk/lp/flights/muc/lhr/munich-to-london) - [Flights from Manchester to Stuttgart](https://expedia.co.uk/lp/flights/man/str/manchester-to-stuttgart) - [Lufthansa London (LHR) to Munich (MUC) flights](https://expedia.co.uk/lp/flight-routes/lufthansa-from-heathrow-to-franz-josef-strauss-intl/lh/lhr/muc) - [Flights from Glasgow to Munich](https://expedia.co.uk/lp/flights/gla/muc/glasgow-to-munich) - [Flights from London to Munich](https://expedia.co.uk/lp/flights/lhr/muc/london-to-munich) - [Flights from Birmingham to Hamburg](https://expedia.co.uk/lp/flights/bhx/ham/birmingham-to-hamburg) - [Flights from Birmingham to Stuttgart](https://expedia.co.uk/lp/flights/bhx/str/birmingham-to-stuttgart) - [Flights from London to Munich](https://expedia.co.uk/lp/flights/lgw/muc/london-to-munich) - [Flights from Birmingham to Munich](https://expedia.co.uk/lp/flights/bhx/muc/birmingham-to-munich) - [Flights from Edinburgh to Cologne](https://expedia.co.uk/lp/flights/edi/cgn/edinburgh-to-cologne) - [Flights from London to Dortmund](https://expedia.co.uk/lp/flights/lhr/dtm/london-to-dortmund) - [Flights from Cologne to London](https://expedia.co.uk/lp/flights/cgn/lhr/cologne-to-london) - [Flights from Newcastle to Munich](https://expedia.co.uk/lp/flights/ncl/muc/newcastle-to-munich) - [Flights from Edinburgh to Munich](https://expedia.co.uk/lp/flights/edi/muc/edinburgh-to-munich) - [Flights from London to Cologne](https://expedia.co.uk/lp/flights/lgw/cgn/london-to-cologne) - [Flights from London to Düsseldorf](https://expedia.co.uk/lp/flights/lhr/dus/london-to-dusseldorf) - [Flights from Newcastle to Dortmund](https://expedia.co.uk/lp/flights/ncl/dtm/newcastle-to-dortmund) - [Flights from Manchester to Cologne](https://expedia.co.uk/lp/flights/man/cgn/manchester-to-cologne) - [Flights from Düsseldorf to London](https://expedia.co.uk/lp/flights/dus/lhr/dusseldorf-to-london) - [Flights from Manchester to Munich](https://expedia.co.uk/lp/flights/man/muc/manchester-to-munich) - [Flights from London to Dresden](https://expedia.co.uk/lp/flights/lhr/drs/london-to-dresden) - [Flights from London to Stuttgart](https://expedia.co.uk/lp/flights/lhr/str/london-to-stuttgart) - [Flights from London to Cologne](https://expedia.co.uk/lp/flights/lhr/cgn/london-to-cologne) - [Flights from Hamburg to London](https://expedia.co.uk/lp/flights/ham/lhr/hamburg-to-london) \*Available to Expedia members. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)