Title: £543 Cheap Flights from Porto to São Tomé Island (OPO to TMS) - Expedia.co.uk ![Adobe](https://images.trvl-media.com/place/3486/703f69b0-0f4e-4999-b953-08659a8d079c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3486/703f69b0-0f4e-4999-b953-08659a8d079c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £543 Cheap Flights from Porto (OPO) to São Tomé Island (TMS) [View £543 flight on Tue, 10 Mar 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:OPO,to:TMS,departure:10/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:543.00&airProductToken=AQpvCjUI1KABEgQxOTM1GO5zIIuSASiQo4cDMMyjhwM4QUAAWAFqCERJU0NPVU5UcghBTDBEU0kwNQo2CNSgARIEMTUyNxiLkgEgk5MBKL-phwMwva2HAzhBQAFYAWoIRElTQ09VTlRyCEFMMERTSTA1EgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Porto Airport (OPO) to São Tomé Island (TMS-São Tomé Intl.) - ![TAP Portugal](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TP.svg) TAP Portugal [](https://www.expedia.co.uk/Flights-Search?leg1=from:OPO,to:TMS,departure:08/01/2026TANYT&leg2=from:TMS,to:OPO,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TP"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Porto (OPO) to São Tomé Island (TMS) Prices were available within the past 7 days and start at £543 for one-way flights and £1,372 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 5 Mar - Fri, 13 Mar OPO Porto TMS São Tomé Island £1,372 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:TMS,departure:05/03/2026TANYT&leg2=from:TMS,to:OPO,departure:13/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1371.90&airProductToken=AQptCjQI1KABEgQxOTMxGO5zIIuSASiA6YYDMMHphgM4QUAAWAFqB0RJU0NJTlRyCEFMMERTSTA1CjUI1KABEgQxNTI3GIuSASCTkwEon_GGAzCd9YYDOEFAAFgBagdESVNDSU5UcghBTDBEU0kwNRIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 5 Mar - Fri, 13 Mar OPO Porto TMS São Tomé Island £1,410 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:TMS,departure:05/03/2026TANYT&leg2=from:TMS,to:OPO,departure:13/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1409.60&airProductToken=AQprCjMI1KABEgQxOTMxGO5zIIuSASiA6YYDMMHphgM4QUAAWAFqBkJBU0lOVHIIQUwwQlNJMDUKNAjUoAESBDE1MjcYi5IBIJOTASif8YYDMJ31hgM4QUAAWAFqBkJBU0lOVHIIQUwwQlNJMDUSCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 5 Mar - Fri, 13 Mar OPO Porto TMS São Tomé Island £1,459 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:TMS,departure:05/03/2026TANYT&leg2=from:TMS,to:OPO,departure:13/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1458.60&airProductToken=AQprCjMI1KABEgQxOTMxGO5zIIuSASiA6YYDMMHphgM4QUAAWAFqBkNMQUlOVHIIQUwwQ0xJMDUKNAjUoAESBDE1MjcYi5IBIJOTASif8YYDMJ31hgM4QUAAWAFqBkNMQUlOVHIIQUwwQ0xJMDUSCggBEAEYASoCVFAYASIECAEQASgCKAMoBDAN) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 5 Mar - Fri, 13 Mar OPO Porto TMS São Tomé Island £1,507 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:TMS,departure:05/03/2026TANYT&leg2=from:TMS,to:OPO,departure:13/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1506.50&airProductToken=AQptCjQI1KABEgQxOTMxGO5zIIuSASiA6YYDMMHphgM4QUAAWAFqB1BMVVNJTlRyCEFMMFBVSTA1CjUI1KABEgQxNTI3GIuSASCTkwEon_GGAzCd9YYDOEFAAFgBagdQTFVTSU5UcghBTDBQVUkwNRIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 22 Jan - Thu, 29 Jan OPO Porto TMS São Tomé Island £2,014 Return found 4 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:OPO,to:TMS,departure:22/01/2026TANYT&leg2=from:TMS,to:OPO,departure:29/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:2013.10&airProductToken=AQpvCjUI1KABEgQxOTM1GO5zIIuSASiwkoMDMOySgwM4QUAAWAFqCERJU0NPVU5UcghBTDBEU0kwNQo2CNSgARIEMTUyNxiLkgEgk5MBKN-YgwMw3ZyDAzhBQAFYAWoIRElTQ09VTlRyCEFMMERTSTA1EgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwAQ) __Flight from Porto to São Tomé Island route information__ | Origin airport | Dr. Francisco de Sa Carneiro | | ------------------- | ---------------------------- | | Destination airport | São Tomé Intl. | | Return price | £1,372 | | Distance | 4772 km | ## Compare flights from Porto to São Tomé Island easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Porto to São Tomé Island. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to São Tomé Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Dr. Francisco de Sa Carneiro to São Tomé Intl.. To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. Grab a great deal on your flight from Dr. Francisco de Sa Carneiro (OPO) to São Tomé Intl. (TMS) The easiest way to view the best deals on flights from Porto to São Tomé Island today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Dr. Francisco de Sa Carneiro to São Tomé Intl. start at just £1,372 and range up to £2,014\. To find an even better deal, try - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Porto and São Tomé Island - booking your flight during March, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper Why you should book your Porto to São Tomé Island flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Dr. Francisco de Sa Carneiro to São Tomé Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you. Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight. ## Explore a world of travel with Expedia - Accommodation - [Água Grande Hotels ](https://www.expedia.co.uk/Destinations-In-Agua-Grande.d553248635976006815.Hotel-Destinations) - [Hotels near Estadio Nacional 12 de Julho ](https://www.expedia.co.uk/Estadio-Nacional-12-De-Julho-Hotels.0-l6118168-0.Travel-Guide-Filter-Hotels) - [São Tomé Hotels ](https://www.expedia.co.uk/Sao-Tome-Hotels.d553248635975177343.Travel-Guide-Hotels) \*Available to Expedia members.