Title: Cheap Flights from Detroit to St. Louis (DTW to SUS) - Expedia.co.uk ![](https://images.trvl-media.com/place/178309/1d118261-eb93-42dd-aeef-5f82e1f037e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/178309/1d118261-eb93-42dd-aeef-5f82e1f037e8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Detroit (DTW) to St. Louis (SUS) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to St. Louis, MO (SUS-Spirit of St. Louis) - ![British Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg) British Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:dtw,to:sus,departure:16/11/2025TANYT&leg2=from:sus,to:dtw,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}]) - ![easyJet](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_U2.svg) easyJet [](https://www.expedia.co.uk/Flights-Search?leg1=from:dtw,to:sus,departure:16/11/2025TANYT&leg2=from:sus,to:dtw,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"U2"}}]) - ![Lufthansa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg) Lufthansa [](https://www.expedia.co.uk/Flights-Search?leg1=from:dtw,to:sus,departure:16/11/2025TANYT&leg2=from:sus,to:dtw,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}]) - ![Ryanair](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_FR.svg) Ryanair [](https://www.expedia.co.uk/Flights-Search?leg1=from:dtw,to:sus,departure:16/11/2025TANYT&leg2=from:sus,to:dtw,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"FR"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dtw,to:sus,departure:16/11/2025TANYT&leg2=from:sus,to:dtw,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Jet2](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LS.svg) Jet2 [](https://www.expedia.co.uk/Flights-Search?leg1=from:dtw,to:sus,departure:16/11/2025TANYT&leg2=from:sus,to:dtw,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LS"}}]) - ![Swiss International Air Lines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LX.svg) Swiss International Air Lines [](https://www.expedia.co.uk/Flights-Search?leg1=from:dtw,to:sus,departure:16/11/2025TANYT&leg2=from:sus,to:dtw,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LX"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Travel information | Origin airport | Detroit Metropolitan Wayne County | | --- | --- | | Destination airport | Spirit of St. Louis | | Distance | 728 km | ## Book with confidence ### Compare flights from Detroit to St. Louis easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Detroit to St. Louis. Operating between them flights per day, airlines cover the route. And fly direct, getting you to Spirit of St. Louis in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Detroit Metropolitan Wayne County to Spirit of St. Louis.   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Detroit Metropolitan Wayne County (DTW) to Spirit of St. Louis (SUS) The easiest way to view the best deals on flights from Detroit to St. Louis today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Detroit Metropolitan Wayne County to Spirit of St. Louis start at just and range up to .   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Detroit and St. Louis - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Detroit to St. Louis flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Detroit Metropolitan Wayne County to Spirit of St. Louis for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Flights - [Flights from Aberdeen (ABZ) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/abz/stl/aberdeen-to-st-louis) - [Flights from Accra (ACC) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/acc/stl/accra-to-st-louis) - [Flights from Albany (ALB) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/alb/stl/albany-to-st-louis) - [Flights from Amsterdam (AMS) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/ams/stl/amsterdam-to-st-louis) - [Flights from St. John's (ANU) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/anu/stl/st-johns-to-st-louis) - [Flights from Astrakhan (ASF) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/asf/stl/astrakhan-to-st-louis) - [Flights from Atlanta (ATL) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/atl/stl/atlanta-to-st-louis) - [Flights from Austin (AUS) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/aus/stl/austin-to-st-louis) - [Flights from Belfast (BFS) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/bfs/stl/belfast-to-st-louis) - [Flights from Birmingham (BHM) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/bhm/stl/birmingham-to-st-louis) - [Flights from Birmingham (BHX) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/bhx/stl/birmingham-to-st-louis) - [Flights from Nashville (BNA) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/bna/stl/nashville-to-st-louis) - [Flights from Boston (BOS) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/bos/stl/boston-to-st-louis) - [Flights from Bristol (BRS) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/brs/stl/bristol-to-st-louis) - [Flights from Baltimore (BWI) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/bwi/stl/baltimore-to-st-louis) - [Flights from Bolzano (BZO) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/bzo/stl/bolzano-to-st-louis) - [Flights from Columbia (CAE) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/cae/stl/columbia-to-st-louis) - [Flights from Paris (CDG) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/cdg/stl/paris-to-st-louis) - [Flights from Columbus (CMH) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/cmh/stl/columbus-to-st-louis) - [Flights from Colorado Springs (COS) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/cos/stl/colorado-springs-to-st-louis) - [Flights from Cincinnati (CVG) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/cvg/stl/cincinnati-to-st-louis) - [Flights from Cardiff (CWL) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/cwl/stl/cardiff-to-st-louis) - [Flights from Washington (DCA) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/dca/stl/washington-to-st-louis) - [Flights from Dallas (DFW) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/dfw/stl/dallas-to-st-louis) - [Flights from Des Moines (DSM) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/dsm/stl/des-moines-to-st-louis) - [Flights from Detroit (DTW) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/dtw/stl/detroit-to-st-louis) - [Flights from Dublin (DUB) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/dub/stl/dublin-to-st-louis) - [Flights from Dubai (DXB) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/dxb/stl/dubai-to-st-louis) - [Flights from Entebbe (EBB) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/ebb/stl/entebbe-to-st-louis) - [Flights from Edinburgh (EDI) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/edi/stl/edinburgh-to-st-louis) - [Flights from East Midlands (EMA) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/ema/stl/east-midlands-to-st-louis) - [Flights from Nema (EMN) to St. Louis (STL)](https://www.expedia.co.uk/lp/flights/emn/stl/nema-to-st-louis) - [Flights from Newark Liberty Intl. 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