Title: All Hotels by Independent in Vendicari Natural Reserve - 2026 Updated Prices | Expedia.co.uk [Vendicari Natural Reserve Travel Guide](https://expedia.co.uk/Vendicari-Natural-Reserve.dx6182494)[Hotels in Vendicari Natural Reserve](https://expedia.co.uk/Vendicari-Natural-Reserve-Hotels.d6182494.Travel-Guide-Hotels)[Holiday Rentals in Vendicari Natural Reserve](https://expedia.co.uk/Vendicari-Natural-Reserve-Holiday-Rentals.d6182494.Travel-Guide-HolidayRentals)[Flights to Vendicari Natural Reserve](https://expedia.co.uk/Cheap-Flights-To-Vendicari-Natural-Reserve.d6182494.Travel-Guide-Flights)[Vendicari Natural Reserve Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Vendicari-Natural-Reserve.d6182494.Car-Hire-Guide)[Vendicari Natural Reserve Holidays](https://expedia.co.uk/Vendicari-Natural-Reserve.d6182494.Holidays-City-Breaks) ![Spiaggia di Cala Mosche. One of the many slightly hidden beaches of south-eastern Sicily](https://images.trvl-media.com/place/6034839/b859b779-e22e-4f36-91ce-29a600d3857b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Matthew Thode ![](https://images.trvl-media.com/place/6034839/b859b779-e22e-4f36-91ce-29a600d3857b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [25 Mar - 26 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2026-03-25&endDate=2026-03-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [26 Mar - 27 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2026-03-26&endDate=2026-03-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6182494&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FVendicari-Natural-Reserve-Hotels-Independent.0-0-d6182494--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FVendicari-Natural-Reserve-Hotels-Independent.0-0-d6182494--bIndependent.Travel-Guide-Filter-Hotels) ## Top Vendicari Natural Reserve Hotel Reviews ![Domus Mariae Albergo](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/121efcd2_y.jpg) ### Domus Mariae Albergo 10/10 Excellent "Awesome boutique hotel with cats and nuns—great views of the sea from some rooms. If you’re looking for a 3-star hotel in a superb location with very kind staff, you can’t go wrong here!" [](https://expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Maniace Boutique Hotel Ortigia UNA Esperienze](https://images.trvl-media.com/lodging/110000000/109090000/109087400/109087329/9c7a5849_y.jpg) ### Maniace Boutique Hotel Ortigia UNA Esperienze 10/10 Excellent "My husband and I had an amazing time. The location was ideal. Very close to shopping and restaurants but very quiet. Everyone there was so nice and helpful and the breakfast was perfect for a day of roaming around. We will stay here every time we visit Ortigia" [](https://expedia.co.uk/Syracuse-Hotels-Maniace-Boutique-Hotel-Ortigia.h109087329.Hotel-Information) ![Algila' Ortigia Charme Hotel](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/b9b70cd2_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "Excellent breakfast and wonderful staff. Location is great" [](https://expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Maecò Ortigia B&B](https://images.trvl-media.com/lodging/28000000/27370000/27369700/27369601/955b55b4_y.jpg) ### Maecò Ortigia B&B 10/10 Excellent "The staff were so friendly and welcoming and the rooms really comfortable and so clean. The whole place was warm ,which was a benefit as the weather outside was distinctly wet and cold.( It was March) The breakfast was all you could wish for and the communal table was an opportunity to meet and talk to people from all over the world. Highly recommended." [](https://expedia.co.uk/Syracuse-Hotels-Maeco-Ortigia-BB.h27369601.Hotel-Information) ![Lanterne Magiche Ortigia](https://images.trvl-media.com/lodging/19000000/18710000/18704100/18704044/266affcc_y.jpg) ### Lanterne Magiche Ortigia 10/10 Excellent "Very good stay" [](https://expedia.co.uk/Syracuse-Hotels-Lanterne-Magiche-Ortigia.h18704044.Hotel-Information) ![Grand Hotel Ortigia Siracusa](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/ac752df8_y.jpg) ### Grand Hotel Ortigia Siracusa 6/10 Okay "Superb staff, Emanuel at front desk went above and beyond printing out maps and providing suggestions for day trips. Hotel and rooms are very dated and lack a cohesive look. Bathroom smelled of sewage and the entire hotel had the smell of grandma’s awful perfume. Rooms are small, location is superb and right on the water. Amazing views from the top floor restaurant. Wait staff fantastic and very attentive." [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![L'Approdo delle Sirene](https://images.trvl-media.com/lodging/3000000/2530000/2527300/2527263/fe44f2b7_y.jpg) ### L'Approdo delle Sirene 10/10 Excellent "We had such a lovely room, the private patio was gorgeous with many health plants and panoramic views of Ortigia. We could see the city on the right and the sea on the left. With the wooden table & chairs we had a lovely breakfast out there with a view and we were able to catch a beautiful sunset on our first night without having to leave. The staff made us feel comfortable and welcome, and the room was very clean & quiet. We would absolutely come back again." [](https://expedia.co.uk/Syracuse-Hotels-LApprodo-Delle-Sirene.h2527263.Hotel-Information) ![Caportigia Boutique Hotel](https://images.trvl-media.com/lodging/18000000/17520000/17519100/17519019/83105a89_y.jpg) ### Caportigia Boutique Hotel 10/10 Excellent "Excellent modern property, staff are all amazing. Walkable to everything." [](https://expedia.co.uk/Syracuse-Hotels-Caportigia-Boutique-Hotel.h17519019.Hotel-Information) ![Archinuè Suite & Apartments](https://images.trvl-media.com/lodging/23000000/22120000/22110600/22110520/9fb412e9_y.jpg) ### Archinuè Suite & Apartments 10/10 Excellent "Great location, very clean and spacious." 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