Title: TOP Casino Hotels in Southwest Illinois, IL for 2025 | Expedia.co.uk [Southwest Illinois Travel Guide](https://expedia.co.uk/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Holiday Rentals in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Holiday-Rentals.d6058943.Travel-Guide-HolidayRentals)[Flights to Southwest Illinois](https://expedia.co.uk/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Things to do in Southwest Illinois](https://expedia.co.uk/Things-To-Do-In-Southwest-Illinois.d6058943.Travel-Guide-Activities)[Southwest Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest-Illinois.d6058943.Car-Hire-Guide)[Southwest Illinois Holidays](https://expedia.co.uk/Southwest-Illinois.d6058943.Holidays-City-Breaks) ![Southern Illinois featuring cycling, autumn colours and forest scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208701-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Casino Hotels in Southwest Illinois ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Illinois Casino Hotels Tonight [21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-09-21&endDate=2025-09-22&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Sept - 23 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-09-22&endDate=2025-09-23&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=CASINO&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southwest Illinois Casino Hotels ![Premium bedding, pillow-top beds, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1790000/1782700/1782652/c5296536.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1790000/1782700/1782652/1f22e905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/2000000/1790000/1782700/1782652/d03aecc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1790000/1782700/1782652/051c3d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge & Suites Granite City Granite City 6.2/10 (237) "Overall the stay was adequate, right off the highway so convenient." £57 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Econo-Lodge-Suites-Granite-City.h1782652.Hotel-Information) ![Suite, 1 King Bed, Non Smoking (Accessible Tub) | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/220000/218600/218540/d0ef6db8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/218600/218540/3726d30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/218600/218540/0cb39698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/220000/218600/218540/cd2efb07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites near St. Louis and I-255 Cahokia 7.4/10 Good (1008) "It meets my expectations and the staff were nice." £59 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Collinsville-Hotels-Quality-Inn-Suites.h218540.Hotel-Information) ![Room, 2 Queen Beds, Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/9000000/8070000/8068200/8068118/c474fdff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/9000000/8070000/8068200/8068118/9aa7ebc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8070000/8068200/8068118/3fff2726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8070000/8068200/8068118/ebdad0b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### First Western Inn Fairmont City 6.4/10 (354) "It was a good trip check in was fast and room are very clean" £60 includes taxes & fees 22 Sept - 23 Sept [](https://www.expedia.co.uk/Collinsville-Hotels-First-Western-Inn.h8068118.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-05&endDate=2025-10-06®ionId=6058943&adults=2&amenities=CASINO&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southwest Illinois ### Discover top Southwest Illinois attractions Southwest Illinois offers an enticing blend of casino excitement and family-friendly activities that cater perfectly to travellers seeking a premium experience. At the top of the list is the Argosy Casino Alton, where you’ll find a variety of gaming options, from slots to table games, all set against the backdrop of the scenic Mississippi River. For those who enjoy a bit of nature alongside their gaming, the nearby Riverlands Migratory Bird Sanctuary provides a stunning setting for birdwatching and leisurely walks. If you’re travelling with children, the St. Louis Science Center is just a short drive away and offers hands-on exhibits and a planetarium that are sure to delight. After a day of gaming and exploration, unwind at the exquisite hotels in the area, such as the Hilton St. Louis at the Ballpark, which not only provides luxurious accommodations but also stunning views of the St. Louis skyline. The nearby Laclede's Landing is perfect for evening strolls, featuring a vibrant atmosphere with shops and restaurants, ensuring that every moment of your stay is filled with excitement and relaxation. ## Top Southwest Illinois Hotel Reviews ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [4 Star Hotels in Swansea](https://www.expedia.co.uk/4Star-Swansea-Hotels.s40-0-d164131.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Marissa](https://www.expedia.co.uk/5Star-Marissa-Hotels.s50-0-d3000434506.Travel-Guide-Filter-Hotels) - [Addieville Hotels](https://www.expedia.co.uk/Addieville-Hotels.d3000420807.Travel-Guide-Hotels) - [Hotels with Gym in Alton](https://www.expedia.co.uk/Alton-Hotels-Hotel-With-Gym.0-0-d6108-thotelwithgym.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Alton](https://www.expedia.co.uk/Alton-Hotels-Hotels-With-Hot-Tubs.0-0-d6108-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Spa Hotels in Alton](https://www.expedia.co.uk/Alton-Hotels-Spa-Hotels.0-0-d6108-tSpaHotels.Travel-Guide-Filter-Hotels) - 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