Title: TOP Safari Hotels in Southwest Florida, FL for 2025 | Expedia.co.uk [Southwest Florida Travel Guide](https://expedia.co.uk/Southwest-Florida.dx6233839)[Hotels in Southwest Florida](https://expedia.co.uk/Southwest-Florida-Hotels.d6233839.Travel-Guide-Hotels)[Holiday Rentals in Southwest Florida](https://expedia.co.uk/Southwest-Florida-Holiday-Rentals.d6233839.Travel-Guide-HolidayRentals)[Flights to Southwest Florida](https://expedia.co.uk/Cheap-Flights-To-Southwest-Florida.d6233839.Travel-Guide-Flights)[Things to do in Southwest Florida](https://expedia.co.uk/Things-To-Do-In-Southwest-Florida.d6233839.Travel-Guide-Activities)[Southwest Florida Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest-Florida.d6233839.Car-Hire-Guide)[Southwest Florida Holidays](https://expedia.co.uk/Southwest-Florida.d6233839.Holidays-City-Breaks) ![Burroughs Home showing a house and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/66000/66136-Fort-Myers.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Safari Hotels in Southwest Florida ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Florida Safari Hotels Tonight [3 Oct - 4 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2025-10-03&endDate=2025-10-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2025-10-04&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233839&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southwest Florida Safari Hotels ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/b1b22c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/c2c3a477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/68455625.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/54000000/53880000/53878700/53878673/f00a123e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly remodeled Parakeet cottage! Walking distance to beach, restaurants, shops! Sanibel 9.2/10 Wonderful (68) "Lovely and clean little place. They have bikes you can use to get around. The island has a great bike/walking trail. " £246 includes taxes & fees 4 Oct - 5 Oct [](https://www.expedia.co.uk/Sanibel-Hotels-Newly-Remodeled-Parakeet-Cottage-Walking-Distance-To-Beach.h53878673.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/36000000/35100000/35093800/35093744/2055d637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/36000000/35100000/35093800/35093744/177ae5b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/36000000/35100000/35093800/35093744/d59aabfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35100000/35093800/35093744/23e0c0f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacay in Luxury! 2 mins to the Beach! Holmes Beach 9.8/10 Exceptional (65) "Great place to stay. The staff was very communicative & made the process very easy. Great place for a stay at the beach. Highly recommended. " £246 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Holmes-Beach-Hotels-Vacay-In-Luxury-So-Close-To-The-Beach.h35093744.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/72000000/71970000/71969500/71969499/77698be9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/72000000/71970000/71969500/71969499/a5183941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/72000000/71970000/71969500/71969499/0d74cad3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/72000000/71970000/71969500/71969499/ab233858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Luxury Suite In The Heart Of Fort Myers Close To Everything! Daniels Corridor 9.4/10 Exceptional (57) "The property was nice and clean and the host was so kind. " £136 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Fort-Myers-Hotels-Cozy-Luxury-Suite-In-The-Heart-Of-Fort-Myers.h71969499.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/f4d4a2d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/70bdc6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/7d50ec16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37780000/37773900/37773827/23aec13d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coastal Chic Cottage "Sandpiper" minutes to the beach! Free bikes Tradewinds 9.0/10 Wonderful (23) "Loved our stay at the cottage. It was a perfect getaway for 2. Short walk to a quiet beach. Convenient to restaurants and Ding Darling.We will be back!" £302 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Sanibel-Hotels-Coastal-Chic-Cottage-Sandpiper-Minutes-To-The-Beach-Free-Bikes-JULY-SAVINGS.h37773827.Hotel-Information) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/16efd129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/bc44f5f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/5676ba27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/38000000/37780000/37774200/37774142/296ee2b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW! Sanibel 9.6/10 Exceptional (46) "Proximity to things to do on the island was great!" £226 includes taxes & fees 7 Oct - 8 Oct [](https://www.expedia.co.uk/Sanibel-Hotels-Sanibel-Style-On-The-East-End-Walk-To-Restaurants.h37774142.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106820000/106814600/106814514/f1e11f2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106820000/106814600/106814514/f96cdadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106820000/106814600/106814514/37223624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106820000/106814600/106814514/a5de6200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ultimate Fishing Retreat- Comfortable and Convenient! Ochopee 9.8/10 Exceptional (13) "Great place" £350 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Chokoloskee-Hotels-Our-Little-Slice-Of-Paradise.h106814514.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/72000000/71780000/71773700/71773667/d638d1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71780000/71773700/71773667/2b29aea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71780000/71773700/71773667/d5f8a88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71780000/71773700/71773667/3a1c70aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Cottage, 40 Acres, Outdoor Kitchen w/ B-que, Campfire, & Horse Stables. LaBelle 9.8/10 Exceptional (75) "3rd time there and will be back! If you want to get away from it all, this is the place to go." £195 includes taxes & fees 4 Oct - 5 Oct [](https://www.expedia.co.uk/LaBelle-Hotels-Country-Cottage-On-40-Acres.h71773667.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/83000000/82710000/82709900/82709805/a61fb0b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/83000000/82710000/82709900/82709805/71948389.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/83000000/82710000/82709900/82709805/3f2980db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/83000000/82710000/82709900/82709805/9e949efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Coastal Vibes w/ Private Pool! Bradenton 9.6/10 Exceptional (31) "Perfect! Would stay again " £260 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Bradenton-Hotels-Great-Location-Private-Pool-And-Dog-Friendly.h82709805.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89540000/89538800/89538761/e21a6e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/90000000/89540000/89538800/89538761/f1dacb4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/90000000/89540000/89538800/89538761/65c479a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89540000/89538800/89538761/a47c680a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Luxurious Condo, King Bed Suite, Waterfront + Pool, Near Downtown Caloosahatchee 9.2/10 Wonderful (28) "Loved our stay! The beds were clean and soft. The laundry machines were so convenient and that balcony was super relaxing and easy to enjoy. The bathrooms were fully equipped and very nice! I loved the Kcup coffee machine and the kitchen island, plus their lighting! Super close to grocery, beaches, and Water Park! " £217 includes taxes & fees 7 Oct - 8 Oct [](https://www.expedia.co.uk/Cape-Coral-Hotels-Renovated-11-22.h89538761.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/78000000/77100000/77091100/77091045/bf51c4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/78000000/77100000/77091100/77091045/e3e876bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/78000000/77100000/77091100/77091045/da050d36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/78000000/77100000/77091100/77091045/553034f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts! Pelican 9.6/10 Exceptional (52) "Visiting family, seeing the Gulf coastRelaxing Beautiful home" £186 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Cape-Coral-Hotels-Bright-Airy-2bed-2bath-Home-8-Mins-To-Beach.h77091045.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-17&endDate=2025-10-18®ionId=6233839&adults=2&recreation_group_explore=safari_on_site&sort=RECOMMENDED&openPlayBack=true) ## Top Southwest Florida Hotel Reviews ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - [Gay-Friendly Hotels in Audubon](https://www.expedia.co.uk/Audubon-Naples-Hotels-Gay-Friendly-Hotel.0-n553248635976469139-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Bonita Springs](https://www.expedia.co.uk/Bonita-Springs-Hotels-Adults-Only-Resorts.0-0-d6403-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Bonita Springs](https://www.expedia.co.uk/Bonita-Springs-Hotels-Beach-Hotels.0-0-d6403-tBeachHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Bonita Springs](https://www.expedia.co.uk/Bonita-Springs-Hotels-Boutique-Hotel.0-0-d6403-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Bonita Springs](https://www.expedia.co.uk/Bonita-Springs-Hotels-Budget-Hotels.0-0-d6403-tBudgetHotels.Travel-Guide-Filter-Hotels) - 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