Title: TOP Historic Hotels in Southeast Iowa for 2026 | Expedia.co.uk [Southeast Iowa Travel Guide](https://expedia.co.uk/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.co.uk/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Holiday Rentals in Southeast Iowa](https://expedia.co.uk/Southeast-Iowa-Holiday-Rentals.d6234151.Travel-Guide-HolidayRentals)[Flights to Southeast Iowa](https://expedia.co.uk/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Southeast Iowa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Iowa.d6234151.Car-Hire-Guide)[Southeast Iowa Holidays](https://expedia.co.uk/Southeast-Iowa.d6234151.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6052570/9ddd26bd-82be-41a2-94d7-8f1f7c77e19f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michael Schuier ![](https://images.trvl-media.com/place/6052570/9ddd26bd-82be-41a2-94d7-8f1f7c77e19f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Iowa Historic Hotels Tonight [29 Mar - 30 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [30 Mar - 31 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southeast Iowa historic hotels ![Smart TV, DVD player, books, music library](https://images.trvl-media.com/lodging/67000000/66970000/66969300/66969287/d75711da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66970000/66969300/66969287/3ab12fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66970000/66969300/66969287/55a8f772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, books, music library](https://images.trvl-media.com/lodging/67000000/66970000/66969300/66969287/474e771e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "THE SHOP" retro 60's [](https://www.expedia.co.uk/Keosauqua-Hotels-Retro-60s-Apartment.h66969287.Hotel-Information) Keosauqua 10/10 Exceptional (54 reviews) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy S. £126 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Keosauqua-Hotels-Retro-60s-Apartment.h66969287.Hotel-Information) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/65000000/64660000/64654700/64654655/b3292afd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/65000000/64660000/64654700/64654655/d429c8e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/65000000/64660000/64654700/64654655/c9ac3677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/65000000/64660000/64654700/64654655/f4072501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stay in Historic Downtown Keokuk [](https://www.expedia.co.uk/Burlington-Hotels-Stay-In-Historic-Downtown-Keokuk.h64654655.Hotel-Information) Keokuk 10/10 Exceptional (3 reviews) "The place was very clean and very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller £130 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Burlington-Hotels-Stay-In-Historic-Downtown-Keokuk.h64654655.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/e5fd8682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/8f3ee30c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/c269f6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/64d77fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Red Front Suite - Sleeps 15 [](https://www.expedia.co.uk/Nauvoo-Hotels-The-Red-Front-Suite-Sleeps-15.h39192154.Hotel-Information) Nauvoo 9.8/10 Exceptional (88 reviews) "Great location, comfortable beds." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane P. £198 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Nauvoo-Hotels-The-Red-Front-Suite-Sleeps-15.h39192154.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/30927266.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/1dd0ec69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/e0f0465e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/58cc1522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Experience Beautiful Pioneer Home In Nauvoo! [](https://www.expedia.co.uk/Nauvoo-Hotels-Experience-Beautiful-Pioneer-Home-In-Nauvoo.h42641186.Hotel-Information) Nauvoo 9.8/10 Exceptional (76 reviews) "Loved staying at the Mix house." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris W. £287 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Nauvoo-Hotels-Experience-Beautiful-Pioneer-Home-In-Nauvoo.h42641186.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/5bb2fe0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/bb3d2583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/c8a07f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/8f36affe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price [](https://www.expedia.co.uk/Keokuk-Hotels-Johnston-Mansion-Bed-And-Breakfast-Price-Shown-Is-Vrbo-Mansion-Price.h23611929.Hotel-Information) Keokuk 9.0/10 Wonderful (2 reviews) "Beautiful place in lovely, walkable neighborhood near the Mississippi. The hosts couldn't have been more accommodating or kind." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn C. £1,453 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Keokuk-Hotels-Johnston-Mansion-Bed-And-Breakfast-Price-Shown-Is-Vrbo-Mansion-Price.h23611929.Hotel-Information) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/100000000/99800000/99795100/99795005/e93e5564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/100000000/99800000/99795100/99795005/1d0f6cc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/100000000/99800000/99795100/99795005/0f8c2951.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/100000000/99800000/99795100/99795005/e74b06bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Idyllic Biggsville Vacation Rental: 10 Mi to River [](https://www.expedia.co.uk/Biggsville-Hotels-Idyllic-Biggsville-Vacation-Rental-10-Mi-To-River.h99795005.Hotel-Information) Biggsville 10/10 Exceptional (3 reviews) "Rooms were clean and the bed was comfortable! Highly recommend this rental. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brennan £153 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Biggsville-Hotels-Idyllic-Biggsville-Vacation-Rental-10-Mi-To-River.h99795005.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-12&endDate=2026-04-13®ionId=6234151&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Iowa Hotel Reviews ![Baymont by Wyndham Keokuk](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087820/37554a0f_y.jpg) ### Baymont by Wyndham Keokuk 6/10 Okay "Ok stay" [](https://expedia.co.uk/Burlington-Hotels-Baymont-By-Wyndham-Keokuk.h5087820.Hotel-Information) ![Quality Inn & Suites Fort Madison near Hwy 61](https://images.trvl-media.com/lodging/1000000/970000/966600/966544/42f91567_y.jpg) ### Quality Inn & Suites Fort Madison near Hwy 61 10/10 Excellent "So clean and the breakfast was amazing " [](https://expedia.co.uk/Burlington-Hotels-Quality-Inn-Suites-Fort-Madison-Near-Hwy-61.h966544.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [1 Star Hotels in Central United States ](https://www.expedia.co.uk/1Star-Central-United-States-Hotels.s10-0-d6209877.Travel-Guide-Filter-Hotels) - 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