Title: TOP Business Hotels in Southeast Iowa for 2026 | Expedia.co.uk [Southeast Iowa Travel Guide](https://expedia.co.uk/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.co.uk/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Holiday Rentals in Southeast Iowa](https://expedia.co.uk/Southeast-Iowa-Holiday-Rentals.d6234151.Travel-Guide-HolidayRentals)[Flights to Southeast Iowa](https://expedia.co.uk/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Southeast Iowa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Iowa.d6234151.Car-Hire-Guide)[Southeast Iowa Holidays](https://expedia.co.uk/Southeast-Iowa.d6234151.Holidays-City-Breaks) ![Found this bridge while exploring. It used to be a railroad bridge, transformed to a buggy bridge, and not after restoration is a walking path bridge. It stretches over a hundred feet and while walking you can still see the old railroad and boards for the buggy. ](https://images.trvl-media.com/place/6052570/9ddd26bd-82be-41a2-94d7-8f1f7c77e19f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michael Schuier ![](https://images.trvl-media.com/place/6052570/9ddd26bd-82be-41a2-94d7-8f1f7c77e19f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Iowa Business Hotels Tonight [13 Feb - 14 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-02-13&endDate=2026-02-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [14 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-02-14&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6234151&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southeast Iowa business-friendly hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/7c968180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, Multiple Beds | Premium bedding, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/814842be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/64ebef69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/ef5745b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites - Fort Madison [](https://www.expedia.co.uk/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) Fort Madison 9.4/10 Exceptional (659 reviews) "Great place and great value. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle £55 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/f895586a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/5af7a4bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/83d7e11b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/71fb2b8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Mt. Pleasant Inn [](https://www.expedia.co.uk/Burlington-Hotels-Best-Western-Mt-Pleasant-Inn.h50061.Hotel-Information) Mount Pleasant 8.2/10 Very good (792 reviews) "Very friendly staff hotel is older could use some upgrades" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela £47 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Burlington-Hotels-Best-Western-Mt-Pleasant-Inn.h50061.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/21fbbb57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/70da34b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/fe34f3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/22d5bdf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Mount Pleasant [](https://www.expedia.co.uk/Burlington-Hotels-AmericInn-By-Wyndham-Mount-Pleasant.h124480.Hotel-Information) Mount Pleasant 8.4/10 Very good (546 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) janet £62 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Burlington-Hotels-AmericInn-By-Wyndham-Mount-Pleasant.h124480.Hotel-Information) ![Indoor pool, open 7:00 AM to 11:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/5f87e5cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/69573161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/7020febd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/9d72170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Keokuk North [](https://www.expedia.co.uk/Burlington-Hotels-Quality-Inn-Suites-Keokuk-North.h42551.Hotel-Information) Keokuk 8.4/10 Very good (757 reviews) "Friendly desk staff and a nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jared £65 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Burlington-Hotels-Quality-Inn-Suites-Keokuk-North.h42551.Hotel-Information) ![Suite, 1 King Bed, Accessible, Non Smoking | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/b3c42063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/9ffd81cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/93e35526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/5f4a562d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Mount Pleasant [](https://www.expedia.co.uk/Burlington-Hotels-Quality-Inn-Suites.h68135.Hotel-Information) Mount Pleasant 8.0/10 Very good (122 reviews) "Check in was easy and fast. Room was clean and quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £44 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Burlington-Hotels-Quality-Inn-Suites.h68135.Hotel-Information) ![Double Room, 2 Double Beds | Pillow-top beds, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/6f24ac33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/d2ec1e54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/fc0d86a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/a8b48190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Mt Pleasant [](https://www.expedia.co.uk/Burlington-Hotels-Super-8-By-Wyndham-Mt-Pleasant.h50062.Hotel-Information) Mount Pleasant 8.2/10 Very good (844 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) peter £50 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Burlington-Hotels-Super-8-By-Wyndham-Mt-Pleasant.h50062.Hotel-Information) ![Indoor pool, open 6 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/b1b8714b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/35b38c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/9448848f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/13412084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Keokuk [](https://www.expedia.co.uk/Burlington-Hotels-Hampton-Inn-Keokuk.h1478193.Hotel-Information) Keokuk 8.8/10 Excellent (646 reviews) "Very good stay. I’ll definitely stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tammy £80 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Burlington-Hotels-Hampton-Inn-Keokuk.h1478193.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/12350ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/290c1bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/af493251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/e53c2f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Burlington by IHG [](https://www.expedia.co.uk/Burlington-Hotels-Holiday-Inn-Express-Hotel-Suites-Burlington.h23041.Hotel-Information) Burlington 8.6/10 Excellent (472 reviews) "Clean room, very comfortable beds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie Or Hank £105 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/Burlington-Hotels-Holiday-Inn-Express-Hotel-Suites-Burlington.h23041.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/24000000/23060000/23056000/23055906/dd7b8040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/24000000/23060000/23056000/23055906/53c734de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/24000000/23060000/23056000/23055906/84a796f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23060000/23056000/23055906/a8f368d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Burlington [](https://www.expedia.co.uk/Burlington-Hotels-Hampton-Inn-Suites-Burlington.h23055906.Hotel-Information) Burlington 9.6/10 Exceptional (318 reviews) "Clean room, nice staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £112 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Burlington-Hotels-Hampton-Inn-Suites-Burlington.h23055906.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227688/eddfffd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds, Non Smoking, Kitchenette | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227688/82f513d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227688/fa0e1577.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, toaster](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227688/b3fc5db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nauvoo Vacation Villas & Condos [](https://www.expedia.co.uk/Nauvoo-Hotels-Nauvoo-Vacation-Villas-Condos.h2227688.Hotel-Information) Nauvoo 9.8/10 Exceptional (424 reviews) "Very nice comfortable property" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carie £116 includes taxes & fees 20 Feb - 21 Feb [](https://www.expedia.co.uk/Nauvoo-Hotels-Nauvoo-Vacation-Villas-Condos.h2227688.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-27&endDate=2026-02-28®ionId=6234151&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6234151) ## Top Southeast Iowa Hotel Reviews ![Quality Inn & Suites Fort Madison near Hwy 61](https://images.trvl-media.com/lodging/1000000/970000/966600/966544/28d171d7_y.jpg) ### Quality Inn & Suites Fort Madison near Hwy 61 10/10 Excellent "I always get the King Suite when I go to Ft. Madison to spend time with family. It is always clean and spacious and staying on the 2nd floor is always quiet." [](https://expedia.co.uk/Burlington-Hotels-Quality-Inn-Suites-Fort-Madison-Near-Hwy-61.h966544.Hotel-Information) ![Cobblestone Inn & Suites - Fort Madison](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/ef5745b9_y.jpg) ### Cobblestone Inn & Suites - Fort Madison 10/10 Excellent "Easy to book" [](https://expedia.co.uk/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![Holiday Inn Express Hotel & Suites Burlington by IHG](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/af493251_y.jpg) ### Holiday Inn Express Hotel & Suites Burlington by IHG 10/10 Excellent "The room was great, and the staff was incredible!! Laura at the front desk was so nice and kind and helpful! She went out of her way to make sure we had everything we needed and she also helped my MIL when she got lost trying to find her room. She baked yummy cookies for all the guests and always had a smile on her face. We only had one complaint. the whirlpool was only lukewarm. We stayed here because of the whirl pool, so that was a big disappointment." [](https://expedia.co.uk/Burlington-Hotels-Holiday-Inn-Express-Hotel-Suites-Burlington.h23041.Hotel-Information) ![Fun City Resort Hotel](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3ad09b6d_y.jpg) ### Fun City Resort Hotel 10/10 Excellent "THE ROOM WAS CLEAN AND THE STAFF WAS FRIENDLY" [](https://expedia.co.uk/Burlington-Hotels-The-PZAZZ-Resort-Hotel.h1803337.Hotel-Information) ![Best Western Mt. Pleasant Inn](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/8cc382f9_y.jpg) ### Best Western Mt. Pleasant Inn 10/10 Excellent "A genuine warm welcome, spotless linens, clean room, hot water and a v good breakfast. Excellent value for money" [](https://expedia.co.uk/Burlington-Hotels-Best-Western-Mt-Pleasant-Inn.h50061.Hotel-Information) ![AmericInn by Wyndham West Burlington](https://images.trvl-media.com/lodging/1000000/560000/550600/550579/55efdccb_y.jpg) ### AmericInn by Wyndham West Burlington 10/10 Excellent "Friendly staff, clean room, comfortable bed, complimentary breakfast. Online pre- check-in & free parking. Like that this location is just off the highway/interstate. " [](https://expedia.co.uk/Burlington-Hotels-AmericInn-By-Wyndham-West-Burlington.h550579.Hotel-Information) ![Comfort Suites Burlington](https://images.trvl-media.com/lodging/2000000/1190000/1183600/1183571/49287866_y.jpg) ### Comfort Suites Burlington 10/10 Excellent "The pool was warm so you can step right in, the beds were comfy, rooms were clean, hotel was clean, very nice! " [](https://expedia.co.uk/Burlington-Hotels-Comfort-Suites-Burlington.h1183571.Hotel-Information) ![Super 8 by Wyndham Burlington](https://images.trvl-media.com/lodging/1000000/60000/50200/50155/bc35d0f9_y.jpg) ### Super 8 by Wyndham Burlington 10/10 Excellent "Clean rooms " [](https://expedia.co.uk/Burlington-Hotels-Super-8-By-Wyndham-Burlington.h50155.Hotel-Information) ![Quality Inn & Suites Keokuk North](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/9d72170d_y.jpg) ### Quality Inn & Suites Keokuk North 10/10 Excellent "Friendly desk staff and a nice breakfast. " [](https://expedia.co.uk/Burlington-Hotels-Quality-Inn-Suites-Keokuk-North.h42551.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Southeast Iowa cost? ### How many business hotels are there in Southeast Iowa? ### Why book your business hotel in Southeast Iowa with Expedia? ### How can I find cheap business hotels in Southeast Iowa? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [1 Star Hotels in Central United States ](https://www.expedia.co.uk/1Star-Central-United-States-Hotels.s10-0-d6209877.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Central United States ](https://www.expedia.co.uk/2Star-Central-United-States-Hotels.s20-0-d6209877.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Historic Route 66 ](https://www.expedia.co.uk/2Star-Historic-Route-66-Hotels.s20-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Historic Route 66 ](https://www.expedia.co.uk/3Star-Historic-Route-66-Hotels.s30-0-d702654640613646336.Travel-Guide-Filter-Hotels) - 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