Title: TOP Business Hotels in South Central Pennsylania, PA for 2025 | Expedia.co.uk [South Central Pennsylania Travel Guide](https://expedia.co.uk/South-Central-Pennsylania.dx6234009)[Hotels in South Central Pennsylania](https://expedia.co.uk/South-Central-Pennsylania-Hotels.d6234009.Travel-Guide-Hotels)[Holiday Rentals in South Central Pennsylania](https://expedia.co.uk/South-Central-Pennsylania-Holiday-Rentals.d6234009.Travel-Guide-HolidayRentals)[Flights to South Central Pennsylania](https://expedia.co.uk/Cheap-Flights-To-South-Central-Pennsylania.d6234009.Travel-Guide-Flights)[South Central Pennsylania Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Central-Pennsylania.d6234009.Car-Hire-Guide)[South Central Pennsylania Holidays](https://expedia.co.uk/South-Central-Pennsylania.d6234009.Holidays-City-Breaks) ![Pennsylvania featuring interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23298-Please-Touch-Museum.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in South Central Pennsylania ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Central Pennsylania Business Hotels Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-10-12&endDate=2025-10-13&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-10-13&endDate=2025-10-14&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6234009&startDate=2025-10-24&endDate=2025-10-26&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Central Pennsylania Business Hotels ![Reception](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/a37400d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/6a433924.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/w1927h819x0y0-dd58c9ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/6b01f10d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Mechanicsburg Mechanicsburg 8.8/10 Excellent (15) "Clean room/Staff was amazing/breakfast was simple and easy" £74 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Mechanicsburg-Hotels-Spark-By-Hilton-Mechanicsburg.h85204.Hotel-Information) ![Standard Room, 2 Queen Beds | Hypo-allergenic bedding, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/9883d31c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/50932fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/9600d7e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/b27bada6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gettysburg Gettysburg Historic District 9.4/10 Exceptional (1146) "Fantastic Hotel, Great location." £109 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Gettysburg-Hotels-Gettysburg-Hotel.h5647.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/7193ca4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/97274627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/13ce4bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/464b76ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Carlisle Carlisle 9.6/10 Exceptional (1205) "It was a very nice stay" £73 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Carlisle-Hotels-Microtel-Inn-Suites-By-Wyndham-Carlisle.h31709458.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22000/21975/aba79d0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22000/21975/e6b7efa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22000/21975/413f7b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/22000/21975/d5ba56fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Greencastle by IHG Greencastle 8.6/10 Excellent (547) " Great place to stay when passing by. " £65 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Greencastle-Hotels-Holiday-Inn-Express-Greencastle.h21975.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/14000000/13310000/13304700/13304657/4f8b3d9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/14000000/13310000/13304700/13304657/70b7c05f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/14000000/13310000/13304700/13304657/0953306f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13310000/13304700/13304657/fd89eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn PA Turnpike - 1-81 Carlisle 9.2/10 Wonderful (1012) "Friendly staff and clean comfortable accommodations." £74 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Carlisle-Hotels-Comfort-Inn-PA-Turnpike-1-81.h13304657.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/abb2a00f_edited_d462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/d00fb6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/724e5d96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1550000/1549800/1549728/d284105f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Appalachian Hotel Carlisle 7.2/10 Good (142) "Great hotel!" £44 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Carlisle-Hotels-Quality-Inn.h1549728.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/d0cf6542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/64e881d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/0d961cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Room amenity](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/7fa5c4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Chambersburg Chambersburg 9.0/10 Wonderful (1004) "Clean room, great staff, parking and good location" £83 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Gettysburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Chambersburg.h3936379.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087809/88f568bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087809/da33e9f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087809/e33870fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/6000000/5090000/5087900/5087809/24140b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Harrisburg-Hershey Harrisburg 8.0/10 Very good (1813) "Great location, friendly staff " £56 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Harrisburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Harrisburg-Hershey.h5087809.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2850000/2844600/2844574/4d1465d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![#23 | Individually decorated, individually furnished, desk, blackout curtains](https://images.trvl-media.com/lodging/3000000/2850000/2844600/2844574/981e3bc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![#30 | Private kitchenette | Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/3000000/2850000/2844600/2844574/db2df9dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![#30 | Individually decorated, individually furnished, desk, blackout curtains](https://images.trvl-media.com/lodging/3000000/2850000/2844600/2844574/9cd76009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Altland House Inn and Suites Abbottstown 9.2/10 Wonderful (390) "Friendly staff, quiet clean room." [](https://www.expedia.co.uk/Gettysburg-Hotels-Altland-House-Inn-And-Suites.h2844574.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/70000/60800/60723/cb683db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/70000/60800/60723/a6f6a22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/70000/60800/60723/w3837h2559x3y0-49c3a5fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/70000/60800/60723/2964492d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Lancaster Lancaster 8.8/10 Excellent (488) "Great stay" £95 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Lancaster-Hotels-Spark-By-Hilton-Lancaster.h60723.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6234009&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top South Central Pennsylania Hotel Reviews ![Parkview Inn & Suites Lancaster ](//images.trvl-media.com/lodging/1000000/810000/809200/809150/c22c2d3d_y.jpg) ### Parkview Inn & Suites Lancaster 10/10 Excellent "It was very clean and comfortable. Very homey atmosphere. Loved that there was a door between the bedroom and and living room. Staff was nice, pool and hot tub were great (with long hours). Good breakfast spread and other amenities. " [](https://expedia.co.uk/Lancaster-Hotels-Country-Inn-Suites-By-Radisson.h809150.Hotel-Information) ![Eden Resort and Suites, BW Premier Collection](//images.trvl-media.com/lodging/1000000/30000/27300/27257/429da8fa_y.jpg) ### Eden Resort and Suites, BW Premier Collection 10/10 Excellent "Very clean up to date hotel." [](https://expedia.co.uk/Lancaster-Hotels-Eden-Resort-And-Suites.h27257.Hotel-Information) ![Crowne Plaza Harrisburg-Hershey by IHG](//images.trvl-media.com/lodging/1000000/30000/27600/27596/67a3b995_y.jpg) ### Crowne Plaza Harrisburg-Hershey by IHG 10/10 Excellent "I had a wonderful experience at the hotel , I have stayed at the Crowne plaza before and enjoyed and will will book next time I'm in town" [](https://expedia.co.uk/Harrisburg-Hotels-Crowne-Plaza-Harrisburg-Hershey.h27596.Hotel-Information) ![Lancaster Suites ](//images.trvl-media.com/lodging/1000000/560000/551000/550914/3556501c_y.jpg) ### Lancaster Suites 10/10 Excellent "we were very pleased with our stay overall. the condition of the room was excellent, as well as the breakfast room. we will recommend your facility to friends" [](https://expedia.co.uk/Lancaster-Hotels-Lancaster-Suites.h550914.Hotel-Information) ![Country Inn & Suites by Radisson, Harrisburg - Hershey West, PA](//images.trvl-media.com/lodging/3000000/2560000/2553600/2553577/9a8d0d0b_y.jpg) ### Country Inn & Suites by Radisson, Harrisburg - Hershey West, PA 10/10 Excellent "Staff was very nice. Hotel is in a convenient area. The only downside would be proximity to the interstate and it can be a bit noisy, but not unbearable. " [](https://expedia.co.uk/Harrisburg-Hotels-Country-Inn-Suites-By-Radisson.h2553577.Hotel-Information) ![Motel 6 Lancaster, PA](//images.trvl-media.com/lodging/1000000/130000/124100/124003/f175975a_y.jpg) ### Motel 6 Lancaster, PA 10/10 Excellent "Clean " [](https://expedia.co.uk/Lancaster-Hotels-Motel-6-Lancaster.h124003.Hotel-Information) ![Wyndham Gettysburg Hotel & Conference Center](//images.trvl-media.com/lodging/2000000/1530000/1521500/1521457/b7064677_y.jpg) ### Wyndham Gettysburg Hotel & Conference Center 10/10 Excellent "Our stay was very good. Rooms are serviced daily. The entire complex - it’s a conference center - is very well done and befitting the Gettysburg area. The dining area is bright and nicely decorated with watercolors of the area. Staff are friendly and competent. The food in the 1863 restaurant is extremely good. Breakfasts are above par. Dinners are also good as is the fare served in the bar. We have stayed here previously, but we are finally caught up with the post Covid traveling, and Wyndham has done an excellent job of returning to above normal. " [](https://expedia.co.uk/Gettysburg-Hotels-Wyndham-Gettysburg.h1521457.Hotel-Information) ![Wyndham Garden York](//images.trvl-media.com/lodging/1000000/20000/17200/17101/aebbb9f4_y.jpg) ### Wyndham Garden York 10/10 Excellent "I apparently did not register correctly with Expedia and Wyndham was expecting us for only 1 night. They were able to add the second night in the same room and gave us a bit of a discount. The desk folks were very helpful. We especially enjoyed the breakfast options. I liked the fact that the hotel was fairly secluded and not on the main highway." [](https://expedia.co.uk/York-Hotels-Wyndham-Garden-York.h17101.Hotel-Information) ![Days Inn by Wyndham Hershey](//images.trvl-media.com/lodging/1000000/20000/16000/15999/3a620bf0_y.jpg) ### Days Inn by Wyndham Hershey 10/10 Excellent "Staff was friendly and attentive to check in and check out. " [](https://expedia.co.uk/Hershey-Hotels-Days-Inn-By-Wyndham-Hershey.h15999.Hotel-Information) ## Frequently asked questions ### How much do business hotels in South Central Pennsylania cost? > Prepare to pay between and per night for business hotels in South Central Pennsylania. Awesome deals on stays that cater to corporate travellers are a few clicks away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### How many business hotels are there in South Central Pennsylania? > When your next meeting or networking event takes you someplace in South Central Pennsylania, there are business hotels to select from. ### Why book your business hotel in South Central Pennsylania with Expedia? > We're here to help you find a fabulous business hotel when work takes you away from home. From conference spaces and room service to on-site cafés and restaurants, our stays have all the amenities you'll need to close that big deal. ### How can I find cheap business hotels in South Central Pennsylania? > Expedia can help you easily locate cheap business hotels in South Central Pennsylania. Look for the "traveller experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work productively and comfortably, like free WiFi and included breakfast. 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