Santissima Annunziata Holidays from £416

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Your Santissima Annunziata Holiday

Take the hassle out of planning your next break with a Santissima Annunziata holiday package. Take in the sounds and sights of this wonderful neighbourhood and experience everything it has to offer. When it's time to explore the sights, you'll find loads of big-name attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or all during your trip to Santissima Annunziata. Don't just think about it — take action! Lock in your ultimate Santissima Annunziata holiday with Expedia and experience travel your way.

Price found within the past 48 hours. Click for updated prices.
Palace Hotel

Palace Hotel

Marco Polo
Save 100% on your flight
£416
per person
28 Oct - 31 Oct
found 12 hours ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
9/10 Wonderful! (139 reviews)
EXE Toscana

EXE Toscana

Mugnano
Save 100% on your flight
£930
per person
28 Oct - 31 Oct
found 12 hours ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
8.4/10 Very good! (853 reviews)
The hotel is located very near the autostrade and outside the walled city. Access is easy and direct. Staff were multi lingual and friendly. English was not a problem. Parking is free. Breakfast is served as a buffet and you do need to notify if you intend to partake. It is 13euros. There is a good variety, but it is the same every day. There is an espresso/coffee machine. Nothing available to order. Amenities. There aren’t any (like fitness room or pool). There are meeting rooms up from the lobby. The restaurant isn’t open beyond breakfast and they only offer the buffet. The bar is only open weekdays in the evening. There is a supermarket next door and a McDonald’s around the corner, both easy walking distance. A bit further are a couple of sit-down restaurants and a very good pizzeria. There are more pizzerias here than Starbucks in Seattle! We would stay there again. The lack of amenities isn’t important to us.

Reviewed on 2 Aug 2026

L'Andana

L'Andana

Save 100% on your flight
£566
per person
15 Oct - 18 Oct
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
9.6/10 Exceptional! (94 reviews)
Excellent place

Reviewed on 9 Sept 2026

Eden Rock Resort

Eden Rock Resort

Save 100% on your flight
£848
per person
23 Oct - 28 Oct
found 1 day ago
Return flight included
London (LGW) to Florence (FLR)
9.8/10 Exceptional! (109 reviews)
Simply stunning, no other details necessary!

Reviewed on 10 Sept 2026

Hotel degli Orafi

Hotel degli Orafi

Historic Centre of Florence
Save 100% on your flight
£545
per person
26 Oct - 29 Oct
found 1 day ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
9.6/10 Exceptional! (1,002 reviews)
We booked 3 nights at the hotel and found the location to be excellent. Within a 15 minute walk to all the major attractions. What we were disappointed in was the staff and accommodations. I asked for directions to the nearest bank ATM and you have thought I was asking for national security codes. We went to the rooftop bar twice in one evening and were told that the outdoor seating had been reserved, for 4 hours at a time. There several other couples that had been told the same thing. We proceeded to dine outdoor across the canal and could see the roof top bar from where we were sitting. We observed the tables not being used for at least 1.5 hours during that 4 hour block. When we back to the hotel after dinner and proceeded to the roof top bar again. We were told the same thing and spoke with 2 other couples that had been told the same thing. When I went to the front desk to inquire about this, the front desk staff couldn’t believe that was going on. I was assured they would follow up with me once they determined what was going on. I never heard from anyone after that. Next morning at breakfast one of the other couples from the bar the night before advised that they had witnessed money being exchanged between the employees and the individuals the seating was reserved for. Very disappointing that we paid for amenities we never were able to enjoy.

Reviewed on 13 Sept 2026

Where to stay in Santissima Annunziata

Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

A historic building with ornate carvings and statues, featuring large wooden doors and steps leading up to it.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

A stone bridge with green shutters over a river.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A bustling European square with historic buildings, shops, and a prominent clock tower.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top hotels in Santissima Annunziata

Four Seasons Hotel Firenze

Four Seasons Hotel Firenze

Borgo Pinti, 99 Florence FI
Fully refundableReserve now, pay when you stay
£1,599
12 Oct - 13 Oct
includes taxes & fees
Four Seasons Hotel Firenze
Forte16 View & Spa

Forte16 View & Spa

Viale Antonio Gramsci 16 Florence FI
£189
14 Oct - 15 Oct
includes taxes & fees
Forte16 View & Spa
Hotel Regency

Hotel Regency

Piazza M. D'Azeglio, 3 Florence FI
£508
11 Oct - 12 Oct
includes taxes & fees
Hotel Regency
See all 497 properties in Santissima Annunziata
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santissima Annunziata travel package cost?
From as low as £416. Yes, you read that right. Our Santissima Annunziata packages are a simple way to stretch your budget. Combine your preferred flights, hotels and rental car and get to know this exciting destination.
If I'm not able to travel, can I cancel my Santissima Annunziata travel package?
Yes you can, and we're here to help. You may be able to cancel or amend your Santissima Annunziata travel package at no cost if you booked in the last 24 hours. However, you may be charged a fee by your airline, hotel or car rental company for older bookings. If your circumstances unexpectedly change, browse our Customer Service Portal for further information.
How do I get a cheap travel package to Santissima Annunziata?
Book everything in the one place with our Santissima Annunziata travel packages. We have incredible bargains on flights, hotels, tours and more that'll keep your hip pocket happy and adventurous side satisfied. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, there are endless opportunities to mix and match as you want.
Does Expedia offer Book Now, Pay Later Santissima Annunziata holidays?
Expedia has joined forces with online lender Klarna to make booking your next break easier on your bank balance. Paying by instalment means you can spread the costs of your next dream escape, leaving you with more cash to spend while you're travelling. Klarna has several payment plans to pick from, so you're sure to find something that fits into your budget. Consider these flexible payment options:
  • Pay monthly holidays: Klarna has manageable monthly payment plans that work for all budgets, so you can lock in that well-earned holiday now.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your holiday in multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, choose a low deposit holiday payment plan from Klarna.
How far in advance should I book my Santissima Annunziata holiday?
It all depends on the airline, but you can usually look up international airfares on Expedia nearly a year in advance. While it's advisable to book ahead of time, lucky customers will occasionally score a cheaper ticket just weeks before departure dates.
What does an Expedia Santissima Annunziata travel package include?
From hotels and airfares to rental cars, Expedia can help you craft a Santissima Annunziata package that fits you. Heading off for a while? Consider a rental car, hotel and flight bundle. If you can only manage a quick getaway, a flight and hotel deal could be what you're after. Experiences can also be added once you've made your booking. Our travel packages make it a breeze to plan and save.
What should I know before booking a Santissima Annunziata travel package?
A travel package can be easier on the credit card than individually booking everything you need for your trip. For example, bundle your hotels, flights and rental cars and land a great deal. Whatever your holiday goals are, you're sure to find a package that matches your budget.
Can I choose my airline with a Santissima Annunziata Expedia travel package?
Yes — that's the beauty of an Expedia package. You can pick and choose your flights, hotels and more. We have access to more than 550 airline partners around the world, so you have loads of choice when putting together your Santissima Annunziata trip.

Stay near popular Santissima Annunziata attractions

A classical marble statue of a muscular male figure with curly hair, standing on a pedestal.
Photo by Siew Peng Theoh

Gallery of the Academy of Florence

9.4/10 (3,190 reviews)
You can browse the exhibits at Gallery of the Academy of Florence, a museum with a story of its own, during your trip to Florence. Experience the acclaimed art galleries and fascinating museums in this vibrant area.
See properties
A marble statue of a standing man in a classical pose, set against a white wall with decorative molding and a coffered ceiling.

Statue of David

9.8/10 (523 reviews)
You can learn about the history of Florence with a trip to Statue of David. Experience the fascinating museums and acclaimed art galleries in this vibrant area.
See properties
A statue of a man on horseback in a public square with people and bicycles around.

Santissima Annunziata Square

9.6/10 (4 reviews)
Find out about the history of Florence with a stop at Santissima Annunziata Square. Experience the acclaimed art galleries and fascinating museums in this vibrant area.
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An ornate church interior with detailed frescoes, gold accents, and a large organ.

Basilica of the Most Holy Annunciation

Learn about the local history of Florence when you take a trip to Basilica of the Most Holy Annunciation. Visit the notable monuments and stunning cathedral in this vibrant area.
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Great Synagogue of Florence

9.0/10 (6 reviews)
Great Synagogue of Florence is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art galleries in this vibrant area.
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Piazza Massimo D'Azeglio

Find out about the history of Florence when you take a trip to Piazza Massimo D'Azeglio. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
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Florence Botanical Gardens

10.0/10 (5 reviews)
Explore the great outdoors at Florence Botanical Gardens, a lovely green space in Florence. Stroll along the area's riverfront or experience its fascinating museums.
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Church of Santa Maria Maddalena dei Pazzi

8.0/10 (2 reviews)
You can learn about the history of Florence when you stop by Church of Santa Maria Maddalena dei Pazzi. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
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Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

£21
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

£18
per adult
94% of travellers recommend
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
Michaelangelo's David

Accademia timed-entry Ticket with App Guide

£33
per adult
90% of travellers recommend
Accademia timed-entry Ticket with App Guide
See all activities in Florence

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.