Santissima Annunziata Holidays from £390

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Santissima Annunziata Holiday

Take the hassle out of planning your next break with a Santissima Annunziata holiday package. Take in the sounds and sights of this wonderful neighbourhood and experience everything it has to offer. When it's time to explore the sights, you'll find loads of big-name attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or all during your trip to Santissima Annunziata. Don't just think about it — take action! Lock in your ultimate Santissima Annunziata holiday with Expedia and experience travel your way.

Price found within the past 48 hours. Click for updated prices.
Eurostars Florence Boutique

Eurostars Florence Boutique

4 out of 5
Historic Centre of Florence
Price was £606, price is now £390 per person
£390
per person
8 Dec - 15 Dec
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
8.6/10 Excellent! (508 reviews)

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Price was £862, price is now £435 per person
£435
per person
8 Dec - 15 Dec
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
7.6/10 Good! (1,003 reviews)
Perfect location

Reviewed on 2 Nov 2026

The Hoxton, Florence

The Hoxton, Florence

4 out of 5
Historic Centre of Florence
Price was £711, price is now £406 per person
£406
per person
22 Jan - 29 Jan
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
9.4/10 Exceptional! (370 reviews)

Hotel L'Orologio Firenze

Hotel L'Orologio Firenze

4 out of 5
Historic Centre of Florence
Price was £812, price is now £503 per person
£503
per person
22 Jan - 29 Jan
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
9.6/10 Exceptional! (1,000 reviews)
Staff was great room needs a bigger bed side table to accommodate a cpap

Reviewed on 29 Oct 2026

Plaza Hotel Lucchesi

Plaza Hotel Lucchesi

4 out of 5
Historic Centre of Florence
Price was £743, price is now £474 per person
£474
per person
22 Jan - 29 Jan
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
9.4/10 Exceptional! (1,002 reviews)
Beautiful hotel! Staff was incredible!! The roof top bar was so beautiful!! Thank you!!

Reviewed on 4 Nov 2026

Where to stay in Santissima Annunziata

Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Santissima Annunziata

Four Seasons Hotel Firenze

Four Seasons Hotel Firenze

5 out of 5
Borgo Pinti, 99 Florence FI
Fully refundableReserve now, pay when you stay
The price is £757 per night from 13 Nov to 14 Nov
£757
13 Nov - 14 Nov
includes taxes & fees
Four Seasons Hotel Firenze
Forte16 View & Spa

Forte16 View & Spa

Viale Antonio Gramsci 16 Florence FI
Fully refundableReserve now, pay when you stay
The price is £95 per night from 1 Dec to 2 Dec
£95
1 Dec - 2 Dec
includes taxes & fees
9.6/10 Exceptional! (1,042 reviews)
"Very convenient , the small kitchen, the pool, beware that in Italy, the heating is not available before November 1st."

Reviewed on 4 Nov 2026

Forte16 View & Spa
Ostello 7 Santi

Ostello 7 Santi

Viale Dei Mille 11 Florence FI
Fully refundableReserve now, pay when you stay
The price is £36 per night from 15 Nov to 16 Nov
£36
15 Nov - 16 Nov
includes taxes & fees
Ostello 7 Santi
See all 509 properties in Santissima Annunziata
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santissima Annunziata travel package cost?
From as low as £390. Yes, you read that right. Our Santissima Annunziata packages are a simple way to stretch your budget. Combine your preferred flights, hotels and rental car and get to know this exciting destination.
If I'm not able to travel, can I cancel my Santissima Annunziata travel package?
Yes you can, and we're here to help. You may be able to cancel or amend your Santissima Annunziata travel package at no cost if you booked in the last 24 hours. However, you may be charged a fee by your airline, hotel or car rental company for older bookings. If your circumstances unexpectedly change, browse our Customer Service Portal for further information.
How do I get a cheap travel package to Santissima Annunziata?
Book everything in the one place with our Santissima Annunziata travel packages. We have incredible bargains on flights, hotels, tours and more that'll keep your hip pocket happy and adventurous side satisfied. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, there are endless opportunities to mix and match as you want.
Does Expedia offer Book Now, Pay Later Santissima Annunziata holidays?
Expedia has joined forces with online lender Klarna to make booking your next break easier on your bank balance. Paying by instalment means you can spread the costs of your next dream escape, leaving you with more cash to spend while you're travelling. Klarna has several payment plans to pick from, so you're sure to find something that fits into your budget. Consider these flexible payment options:

  • Pay monthly holidays: Klarna has manageable monthly payment plans that work for all budgets, so you can lock in that well-earned holiday now.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your holiday in multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, choose a low deposit holiday payment plan from Klarna.

How far in advance should I book my Santissima Annunziata holiday?
It all depends on the airline, but you can usually look up international airfares on Expedia nearly a year in advance. While it's advisable to book ahead of time, lucky customers will occasionally score a cheaper ticket just weeks before departure dates.
What does an Expedia Santissima Annunziata travel package include?
From hotels and airfares to rental cars, Expedia can help you craft a Santissima Annunziata package that fits you. Heading off for a while? Consider a rental car, hotel and flight bundle. If you can only manage a quick getaway, a flight and hotel deal could be what you're after. Experiences can also be added once you've made your booking. Our travel packages make it a breeze to plan and save.
What should I know before booking a Santissima Annunziata travel package?
A travel package can be easier on the credit card than individually booking everything you need for your trip. For example, bundle your hotels, flights and rental cars and land a great deal. Whatever your holiday goals are, you're sure to find a package that matches your budget.
Can I choose my airline with a Santissima Annunziata Expedia travel package?
Yes — that's the beauty of an Expedia package. You can pick and choose your flights, hotels and more. We have access to more than 550 airline partners around the world, so you have loads of choice when putting together your Santissima Annunziata trip.

Stay near popular Santissima Annunziata attractions

A classical marble statue of a muscular male figure with curly hair, standing on a pedestal.
Photo by Siew Peng Theoh
Open Photo by Siew Peng Theoh

Gallery of the Academy of Florence

9.4/10 (3,190 reviews)
You can browse the exhibits at Gallery of the Academy of Florence, a museum with a story of its own, during your trip to Florence. Experience the acclaimed art galleries and fascinating museums in this vibrant area.
See properties

Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

£19
per adult
74% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Reserved Entry Florence Duomo: Express Guided Tour

£17
per adult
80% of travellers recommend
Reserved Entry Florence Duomo: Express Guided Tour
Michaelangelo's David

Accademia timed-entry Ticket with App Guide

£33
per adult
90% of travellers recommend
Accademia timed-entry Ticket with App Guide
See all activities in Florence

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.