Title: Top Motels in Santee in 2026 | Expedia.co.uk [Hotels in Santee](https://expedia.co.uk/Santee-Hotels.d9953.Travel-Guide-Hotels)[Holiday Rentals in Santee](https://expedia.co.uk/Santee-Holiday-Rentals.d9953.Travel-Guide-HolidayRentals)[Santee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d9953.Car-Hire-Guide)[Santee Holidays](https://expedia.co.uk/Santee.d9953.Holidays-City-Breaks) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [24 Apr - 26 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=9953&startDate=2026-05-22&endDate=2026-05-24&adults=2&lodging=MOTEL&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santee motels ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2262fc91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/dc3438b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) Santee 6.8/10 (447 reviews) "The beds are super comfy. I liked how quiet it was in the room and the staff was very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy £63 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/c1880a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/bc8b5a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/b034ff09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2920000/2911400/2911319/3a41c72c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Peach Tree Inn [](https://www.expedia.co.uk/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) St. George 7.4/10 Good (177 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Precious £51 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/St-George-Hotels-Peach-Tree-Inn.h2911319.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/bfdc100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/5f1ffd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Smoking | Bathroom sink](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/13cfcb42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17390000/17380300/17380261/c4ff1065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) Orangeburg 8.2/10 Very good (1,007 reviews) "For the price, it was an excellent value. Check-in was easy and parking " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) jeff £60 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Orangeburg.h17380261.Hotel-Information) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/47b4af62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/783d514f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/cef510a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Private kitchenette | Fridge, microwave](https://images.trvl-media.com/lodging/126000000/125190000/125185400/125185326/60d574cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southern Lodge 601 [](https://www.expedia.co.uk/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information) Orangeburg 6.0/10 (2 reviews) "The room smelled. The tub leaked water all over the floor and it didn’t work. There were dead and living bugs on the floor. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward £57 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/Orangeburg-Hotels-Southern-Lodge-601.h125185326.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/c853f767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/ccb93e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/9fe21eb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/320000/317300/317245/88261caa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Manning [](https://www.expedia.co.uk/Sumter-Hotels-Super-8-By-Wyndham-Manning.h317245.Hotel-Information) Manning 6.4/10 (396 reviews) "The staff was friendly and the room clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) dennis £51 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Sumter-Hotels-Super-8-By-Wyndham-Manning.h317245.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/c9ac8d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/b4a7d12b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/ca4e9299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34400/34400/7655013c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham, Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) Orangeburg 6.8/10 (937 reviews) "Easy check in and out, good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa £48 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Orangeburg-Hotels-Super-8-By-Wyndham.h34400.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-12&endDate=2026-04-13®ionId=9953&adults=2&lodging=MOTEL&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Motels.d9953-aaMotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Motels.d9953-aaMotels.Travel-Guide-Accommodation) ## Top Santee Hotel Reviews ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/d82e6496_y.jpg) ### Hampton Inn Santee-I-95 8/10 Good "This is our first choice when traveling on a road trip along the I-95 interstate. Property is well kept, clean and safe. Staff are always welcoming & attentive. Breakfast is ready by 6:00 a.m, if you are heading out to beat the traffic during your drive. Recommend!" [](https://expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/d2da67e4_y.jpg) ### Baymont by Wyndham Santee 6/10 Okay "Clean room that had been updated. Overall a fine stay for one night but was a bit expensive for what it was. " [](https://expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Quality Inn & Suites Santee I-95](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/cd0ca695_y.jpg) ### Quality Inn & Suites Santee I-95 10/10 Excellent "Had a really clean and comfortable stay here in Santee. No pests, no issues at all—everything was well maintained and taken care of. The room was neat, and the bathroom was clean and in good condition. Really appreciate the housekeeping team for the great job on my room—you can tell they put in the effort. Overall, a smooth and pleasant stay. Would definitely come back." [](https://expedia.co.uk/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35_y.jpg) ### Tru by Hilton Orangeburg 10/10 Excellent "The property was nice. The staff were by far the friendliest people, very helpful and just so nice. Our room was clean, and comfortable. Amenities were good, easy to access, and the breakfast was decent. It was our first time here, and would book again. " [](https://expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/fc94b516_y.jpg) ### Comfort Inn & Suites Santee 8/10 Good "Could be revamped. Outdated and kinda eh. " [](https://expedia.co.uk/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Best Western Plus Santee Inn](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/93ba5eb3_y.jpg) ### Best Western Plus Santee Inn 10/10 Excellent "Great breakfast bar - beautiful location in golf course and easy parking. " [](https://expedia.co.uk/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/4b412627_y.jpg) ### Tru By Hilton Santee 6/10 Okay "no, could not connect to the internet. the staff tried to help but could not either. will not say here again because of this !!!" [](https://expedia.co.uk/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Travelodge by Wyndham Santee](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40_y.jpg) ### Travelodge by Wyndham Santee 6/10 Okay "Second time staying here. Adequate for the cost and our needs. Great location; close proximity to amenities. Easy check-in; friendly, courteous employees. Clean, large ground floor room with comfortable bed, small fridge and microwave. Convenient parking right in front of room." [](https://expedia.co.uk/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 10/10 Excellent "This was a stand out hotel. If you’re traveling through the area this is the place to stay. " [](https://expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ## Find out more about Santee ## Santee Motels information | Number of reviews | 2,964 | | ----------------- | --------- | | Accommodation | 11 Motels | | Lowest Price | £48 | | Highest Price | £63 | ## Frequently asked questions ### What can I expect from a motel trip to Santee? ### What's it like to stay in a motel? ### What are the best motels in Santee? ### What can I do in Santee? ### What's the seasonal weather like in Santee? ### What are my options for getting around Santee while staying in a motel? ## Explore a world of travel with Expedia - More ways to book - [Book Motels in Santee on Expedia.com ](https://www.expedia.com/Santee-Motels.d9953-aaMotels.Travel-Guide-Accommodation)