Title: Hotels in Santa Isabel - Best Santa Isabel Hotels from £26 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Isabel](https://expedia.co.uk/Santa-Isabel-Holiday-Rentals.d553248635975869828.Travel-Guide-HolidayRentals)[Santa Isabel Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Isabel.d553248635975869828.Car-Hire-Guide)[Santa Isabel Holidays](https://expedia.co.uk/Santa-Isabel.d553248635975869828.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Isabel from £26 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Isabel Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico®ionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico®ionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico®ionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=PETS) ## Check prices for these dates Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975869828&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975869828&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975869828&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975869828&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santa Isabel hotels and places to stay ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/185f4103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room | 1 bedroom, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/a39bc3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, open 10:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/883c858a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/d8b2e941.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Araiza Mexicali Mexicali 8.6/10 Excellent (1616) "The pool was amazing " £89 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information) ![Daily cooked-to-order breakfast (MXN 290 per person)](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/928ca1d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/8e09f6a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/3a4ef50e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Ejecutiva King | Living area | 32-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/a09279f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Real Inn Mexicali Civic Center 8.2/10 Very good (1472) "Great staff very accommodating and the hotel was very clean. Great family friendly ." £65 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/4d789164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/70e7eb7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/50e75016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/5d2422db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### One Mexicali Mexicali 7.8/10 Good (1002) "Todo excelente " £53 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-One-Mexicali.h17577142.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/9bc6d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/90810982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/677d7bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/119b35fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Mexicali Mexicali 8.4/10 Very good (1008) "They have good breakfast " £60 includes taxes & fees 1 Nov - 2 Nov [](https://www.expedia.co.uk/Mexicali-Hotels-Sleep-Inn-Mexicali.h24081334.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/9be1b557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/0cad0e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/6e6f2982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/d08d8cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express Plus by Marriott Mexicali Mexicali 8.6/10 Excellent (902) "Perfect location" £64 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/e443b787.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Arcade](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/383d12a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/ee9d5f67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/100934ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Siesta Real Mexicali 8.2/10 Very good (844) "Nice and friendly place " £58 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Siesta-Real.h18301092.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow, 2 Double Beds | 1 bedroom, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/76d898ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/5a6c7074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/abb801cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Lucerna Mexicali Mexicali 9.2/10 Wonderful (1386) "Great stay! " £81 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/edfeecd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | Bathroom | Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/54625619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily cooked-to-order breakfast ](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/0e23dca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | Iron/ironing board, free WiFi, wheelchair access](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/49970db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Azteca de Oro Mexicali Mexicali 7.6/10 Good (411) "Exelente" £30 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Azteca-De-Oro-Mexicali.h10071570.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/fc9185d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/fa7de1ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/1b6e837a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/d5c9e706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Mexicali by IHG Mexicali 9.4/10 Exceptional (1002) "Great hotel, location and service" £111 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Mexicali-Hotels-Holiday-Inn-Express-Suites-Mexicali.h12506422.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/5a8679ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed | View from room](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/67882e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed | Desk, blackout curtains, bed sheets](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/fd4f05d0_edited_7172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/8413905f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Suites Mexicali Cataviña Mexicali 8.0/10 Very good (2100) "Love the location, very clean rooms and very safe " [](https://www.expedia.co.uk/Mexicali-Hotels-Extended-Suites-Mexicali-Catavina.h17969178.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/28a69af3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/3acf53a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/586cc6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Mexicali Mexicali 9.4/10 Exceptional (1003) "Nice place to stay, many dining options close by. " £86 includes taxes & fees 1 Nov - 2 Nov [](https://www.expedia.co.uk/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/2e8db822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/58d45afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/975cd623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/da930419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Calafia Hotel Eguía 8.2/10 Very good (1004) "Love the area, the staff were super friendly, the rooms were great!" £69 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Calafia-Hotel.h22599.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3b6504b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/e439c29a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/218fae64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3ea225c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Mexicali Mexicali 8.2/10 Very good (1005) "Out stay was Great!!!" £70 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/48bb48a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/0b1abeec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/3134e983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 2 Double Beds | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/7d528f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fiesta Inn Mexicali Civic Center 8.2/10 Very good (1015) "Great Hotel " £64 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Fiesta-Inn-Mexicali.h1152269.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/fbfdde79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/w4000h2662x0y0-04bf55ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/3b84677b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/e359d09d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express Junior by Marriott Mexicali Mexicali 7.8/10 Good (1004) "- staff accommodated my needs friendly friendly and place was quiet enough to relax " £58 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information) ![Daily continental breakfast (MXN 300 per person)](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/980bccaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/4796b47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/21f7b42d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/d898e4f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Colonial Mexicali Civic Center 8.0/10 Very good (1002) "It was affordable, the room was clean and in great condition" [](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Colonial-Mexicali.h916204.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/35c16f11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/2ef4393d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds | 1 bedroom, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/c2ed0c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/c64aab50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Mexicali Mexicali 9.4/10 Exceptional (759) "Great hotel to stay. It’s clean, comfortable and in a nice area. The staff is friendly " £88 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/19520a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/25e2656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/07182baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/926da4c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cosmos Don Carlos Eguía 8.0/10 Very good (475) "Great stay!" [](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Cosmos-Don-Carlos.h18300174.Hotel-Information) ![Deluxe Suite, Jetted Tub | 1 bedroom, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/c266de1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | 1 bedroom, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/d6e80519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/11d3da4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Jetted Tub | 1 bedroom, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/0d0da065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel Cies Mexicali 9.2/10 Wonderful (48) "Great place to stay awesome service " £46 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Motel-Cies.h102634000.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/b9040e72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/cdbb41d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Triple Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/0624ab03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/a66b0fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hacienda del Indio Mexicali 7.2/10 Good (125) "The room was clean and the parking was safe" £29 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Hacienda-Del-Indio.h18759903.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=553248635975869828&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels) ## Top Santa Isabel Hotel Reviews ![Real Inn Mexicali](//images.trvl-media.com/lodging/1000000/610000/600500/600405/928ca1d8_y.jpg) ### Real Inn Mexicali 10/10 Excellent "Great room, wonderful services and clean room" [](https://expedia.co.uk/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information) ![City Express Junior by Marriott Mexicali](//images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/fbfdde79_y.jpg) ### City Express Junior by Marriott Mexicali 10/10 Excellent "Breakfast was varied and ample parking area." [](https://expedia.co.uk/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information) ![City Express Plus by Marriott Mexicali](//images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/9be1b557_y.jpg) ### City Express Plus by Marriott Mexicali 10/10 Excellent "Everything was fine only the beds need change mattress ,add more towels to the room" [](https://expedia.co.uk/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information) ![Hotel Araiza Mexicali](//images.trvl-media.com/lodging/1000000/30000/22600/22592/185f4103_y.jpg) ### Hotel Araiza Mexicali 10/10 Excellent "Good " [](https://expedia.co.uk/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information) ![Hotel Lucerna Mexicali](//images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31_y.jpg) ### Hotel Lucerna Mexicali 10/10 Excellent "Everyone was very hospitable. Would stay here again. " [](https://expedia.co.uk/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information) ![Calafia Hotel](//images.trvl-media.com/lodging/1000000/30000/22600/22599/2e8db822_y.jpg) ### Calafia Hotel 10/10 Excellent "Great place, clean room, affordable prices" [](https://expedia.co.uk/Mexicali-Hotels-Calafia-Hotel.h22599.Hotel-Information) ![Fiesta Inn Mexicali](//images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/48bb48a1_y.jpg) ### Fiesta Inn Mexicali 10/10 Excellent "All the staff was nice and friendly" [](https://expedia.co.uk/Mexicali-Hotels-Fiesta-Inn-Mexicali.h1152269.Hotel-Information) ![Extended Suites Mexicali Cataviña](//images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/5a8679ec_y.jpg) ### Extended Suites Mexicali Cataviña 10/10 Excellent "Todo bien lo único malo es él area de estacionamiento, me tocó dejarlo lejos porque estaba lleno" [](https://expedia.co.uk/Mexicali-Hotels-Extended-Suites-Mexicali-Catavina.h17969178.Hotel-Information) ![City Express by Marriott Mexicali](//images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3b6504b5_y.jpg) ### City Express by Marriott Mexicali 10/10 Excellent "Out stay was Great!!!" [](https://expedia.co.uk/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information) ## More cheap stays in Santa Isabel ![Fairfield Inn & Suites by Marriott Mexicali](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Mexicali Calzada Manuel Gomez Morin 856, Colonia Rivera, Mexicali, BC £86 1 Nov - 2 Nov includes taxes & fees 9.4/10 Exceptional! (1,002 reviews) [](https://expedia.co.uk/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information) ![Motel Las Fuentes](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/794b14f4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel Las Fuentes Blvd Lopez Mateos 1655, Colonia Zacatecas, Mexicali, BC £31 15 Oct - 16 Oct includes taxes & fees 7.8/10 Good! (143 reviews) [](https://expedia.co.uk/Mexicali-Hotels-Motel-Las-Fuentes.h18759923.Hotel-Information) ![HOTEL DON QUIJOTE](https://images.trvl-media.com/lodging/112000000/111350000/111343500/111343437/6318d665_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL DON QUIJOTE Calz Independencia Independencia, 1782, Mexicali, BC [Get rates](https://expedia.co.uk/Hotel-Search?startDate=24%2F10%2F2025&endDate=25%2F10%2F2025&selected=111343437&PinnedHotelID=111343437&HadPinnedHotel=true®ionId=553248635975869828) 6.8/10 (13 reviews) [](https://expedia.co.uk/Mexicali-Hotels-HOTEL-DON-QUIJOTE.h111343437.Hotel-Information) ![Hotel Misión Plaza Mexicali](https://images.trvl-media.com/lodging/102000000/101490000/101486400/101486351/17b18c98_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Misión Plaza Mexicali 366 Av. Francisco I. Madero, Mexicali, BC £33 12 Oct - 13 Oct includes taxes & fees 7.2/10 Good! (46 reviews) [](https://expedia.co.uk/Tijuana-Hotels-Hotel-Mision-Plaza-Mexicali.h101486351.Hotel-Information) ![Motel Diana ](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/9ba5b8f3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel Diana 200 Av. Tabasco Loma Linda, Mexicali, BC £26 12 Oct - 13 Oct includes taxes & fees 10/10 Exceptional! (1 review) [](https://expedia.co.uk/Mexicali-Hotels-Motel-Diana.h117766546.Hotel-Information) ![Loft en Valquirico Centro, Nizza](https://images.trvl-media.com/lodging/108000000/107630000/107629900/107629888/58641d91_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Loft en Valquirico Centro, Nizza Valquirico £162 13 Oct - 14 Oct includes taxes & fees [](https://expedia.co.uk/Mexicali-Hotels-Loft-En-Valquirico-Centro.h107629888.Hotel-Information) ## Frequently asked questions ### What's the best place for a stay in Santa Isabel? > [Hotel Lucerna Mexicali](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information), located 7.5 mi (12.1 km) from the heart of Santa Isabel, is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are [Hotel Araiza Mexicali](https://www.expedia.co.uk/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information) and [Real Inn Mexicali](https://www.expedia.co.uk/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975869828), or [vacation rentals in Santa Isabel](https://www.expedia.co.uk/Santa-Isabel-Holiday-Rentals.d553248635975869828.Travel-Guide-HolidayRentals). ### What are some of the best holiday rentals that Santa Isabel has to offer? > [Gabby's: House Super safe, comfortable and super clean](https://www.expedia.co.uk/Mexicali-Hotels-Gabbys-House-Super-Safe.h100839777.Hotel-Information): This holiday home rental outside of Santa Isabel has laundry facilities and WiFi to help you feel perfectly comfortable in your new surroundings. See all [vacation rentals in Santa Isabel](https://www.expedia.co.uk/Santa-Isabel-Holiday-Rentals.d553248635975869828.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund? > Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975869828&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santa Isabel. ### What is staying in Santa Isabel like? > Visitors to Santa Isabel will definitely find plenty to explore and enjoy. There are 71 hotels and other accommodation options in the surrounding area. Find out more about [Santa Isabel](https://www.expedia.co.uk/Santa-Isabel.dx553248635975869828). ### What is there to see in Santa Isabel? > Places to visit in the wider area include [Gran Plaza Outlets](https://www.expedia.co.uk/Gran-Plaza-Outlets-Calexico.d553248621561088055.Attraction), [Mexicali Border Port I](https://www.expedia.co.uk/Mexicali-Border-Port-I-Mexicali.d553248635998150182.Attraction) and [Plaza Comercial La Cachanilla](https://www.expedia.co.uk/Plaza-Comercial-La-Cachanilla-Zona-Industrial.d6291021.Attraction). You'll also find [Eagles Nest Stadium](https://www.expedia.co.uk/Aguilas-De-Mexicali-Stadium-Mexicali.d6269341.Attraction) and [Imperial Valley Mall](https://www.expedia.co.uk/Imperial-Valley-Mall-El-Centro.d553248621561088057.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [Santa Isabel guide](https://www.expedia.co.uk/Santa-Isabel.dx553248635975869828). ### What's the seasonal weather like in Santa Isabel? > The hottest months are usually July and August, with an average temperature of 34°C, while the coldest months are December and January, with an average of 16°C. 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[Zona Industrial Hotels](https://www.expedia.co.uk/Zona-Industrial-Mexicali-Hotels.0-n553248635976399090-0.Travel-Guide-Filter-Hotels) - [Flights to Ensenada](https://www.expedia.co.uk/Cheap-Flights-To-Ensenada.d6144237.Travel-Guide-Flights) - [Flights to Los Algodones](https://www.expedia.co.uk/Cheap-Flights-To-Los-Algodones.d6158212.Travel-Guide-Flights) - [Flights to Luis Echeverria Alvarez](https://www.expedia.co.uk/Cheap-Flights-To-Luis-Echeverria-Alvarez.d6347195.Travel-Guide-Flights) - [Flights to Mexicali](https://www.expedia.co.uk/Cheap-Flights-To-Mexicali.d2478.Travel-Guide-Flights) - [Flights to Santa Veronica](https://www.expedia.co.uk/Cheap-Flights-To-Santa-Veronica.d6347107.Travel-Guide-Flights) - [Flights to Tecate](https://www.expedia.co.uk/Cheap-Flights-To-Tecate.d179908.Travel-Guide-Flights) - [Flights to Valle de Guadalupe](https://www.expedia.co.uk/Cheap-Flights-To-Valle-De-Guadalupe.d6269310.Travel-Guide-Flights) - [Flights from General Rodolfo Sanchez Taboada Intl.](https://www.expedia.co.uk/lp/airports/mxl/flights-from-general-rodolfo-sanchez-taboada-intl-airport) - [Flights from Mexicali](https://www.expedia.co.uk/lp/flights/2478/flights-from-mexicali) - [Flights from Los Algodones](https://www.expedia.co.uk/lp/flights/6158212/flights-from-los-algodones) - [Flights from Addis Ababa (ADD) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/add/mxl/addis-ababa-to-mexicali) - [Flights from Belfast (BFS) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/bfs/tij/belfast-to-tijuana) - [Flights from Birmingham (BHX) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/bhx/tij/birmingham-to-tijuana) - [Flights from Cancun (CUN) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/cun/tij/cancun-to-tijuana) - [Flights from Chihuahua (CUU) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/cuu/mxl/chihuahua-to-mexicali) - [Flights from Calexico (CXL) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/cxl/mxl/calexico-to-mexicali) - [Flights from Edinburgh (EDI) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/edi/tij/edinburgh-to-tijuana) - [Flights from Guadalajara (GDL) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/gdl/tij/guadalajara-to-tijuana) - [Flights from Grand Junction (GJT) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/gjt/mxl/grand-junction-to-mexicali) - [Flights from Las Vegas (LAS) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/las/tij/las-vegas-to-tijuana) - [Flights from Los Angeles (LAX) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/lax/tij/los-angeles-to-tijuana) - [Flights from London (LGW) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/lgw/tij/london-to-tijuana) - [Flights from London (LHR) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/lhr/mxl/london-to-mexicali) - [Flights from London (LHR) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/lhr/tij/london-to-tijuana) - [Flights from Manchester (MAN) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/man/mxl/manchester-to-mexicali) - [Flights from Manchester (MAN) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/man/tij/manchester-to-tijuana) - [Flights from Mexico City (MEX) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/mex/mxl/mexico-city-to-mexicali) - [Flights from Mexico City (MEX) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/mex/tij/mexico-city-to-tijuana) - [Flights from Milan (MXP) to Mexicali (MXL)](https://www.expedia.co.uk/lp/flights/mxp/mxl/milan-to-mexicali) - [Flights from Newcastle (NCL) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/ncl/tij/newcastle-to-tijuana) - [Flights from Puerto Vallarta (PVR) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/pvr/tij/puerto-vallarta-to-tijuana) - [Flights from San Francisco (SFO) to Tijuana (TIJ)](https://www.expedia.co.uk/lp/flights/sfo/tij/san-francisco-to-tijuana) - [Visit Zona Centro](https://www.expedia.co.uk/Ensenada-Zona-Centro.dx553248635976007931) - [Ensenada Holidays](https://www.expedia.co.uk/Ensenada.d6144237.Holidays-City-Breaks) - [Visit Ensenada](https://www.expedia.co.uk/Ensenada.dx6144237) - [Juventud 2000 Sport Center](https://www.expedia.co.uk/Juventud-2000-Sport-Center-Mexicali.d553248621551385142.Attraction) - [Visit La Rumorosa](https://www.expedia.co.uk/La-Rumorosa.dx553248635823471502) - [Mexicali Holidays](https://www.expedia.co.uk/Mexicali.d2478.Holidays-City-Breaks) - [Visit Mexicali](https://www.expedia.co.uk/Mexicali.dx2478) - [Monte Xanic Winery](https://www.expedia.co.uk/Monte-Xanic-Winery-Valle-de-Guadalupe.d553248621532630241.Attraction) - [Playas de Rosarito Holidays](https://www.expedia.co.uk/Playas-De-Rosarito.d553248635943688104.Holidays-City-Breaks) - [Visit Playas de Rosarito](https://www.expedia.co.uk/Playas-De-Rosarito.dx553248635943688104) - [Sol Children's Museum](https://www.expedia.co.uk/Sol-Childrens-Museum-Zona-Industrial.d6224748.Attraction) - [Tecate Holidays](https://www.expedia.co.uk/Tecate.d179908.Holidays-City-Breaks) - [Visit Tecate](https://www.expedia.co.uk/Tecate.dx179908) - [Visit Garita de Otay](https://www.expedia.co.uk/Tijuana-Garita-De-Otay.dx553248635976007811) - [Visit Rinconada de Otay](https://www.expedia.co.uk/Tijuana-Rinconada-De-Otay.dx553248635976007603) - [Valle de Guadalupe Holidays](https://www.expedia.co.uk/Valle-De-Guadalupe.d6269310.Holidays-City-Breaks) - [Visit Valle de Guadalupe](https://www.expedia.co.uk/Valle-De-Guadalupe.dx6269310) - [Winery Santo Tomas](https://www.expedia.co.uk/Winery-Santo-Tomas-Valle-de-Guadalupe.d553248634214860757.Attraction) - [Car hire Ensenada](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Ensenada.d6144237.Car-Hire-Guide) - [Car hire Mexicali](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Mexicali.d2478.Car-Hire-Guide) - [Valle de Guadalupe Holiday Rentals](https://www.expedia.co.uk/Valle-De-Guadalupe-Holiday-Rentals.d6269310.Travel-Guide-HolidayRentals) - [Things to do in Ensenada](https://www.expedia.co.uk/Things-To-Do-In-Ensenada.d6144237.Travel-Guide-Activities) - [Book Hotels in Santa Isabel on Expedia.mx](https://www.expedia.mx/Santa-Isabel-Hoteles.d553248635975869828.Guia-Viajes-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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