Santa Isabel Holidays

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Your Santa Isabel Holiday

Our holiday packages to Santa Isabel give you endless opportunities to immerse yourself in new sights, sounds and sensations. And with all the details taken care of, you'll be free to enjoy your city adventure to the fullest. Make your trip to Santa Isabel even more fun and exciting by including some sightseeing. Plaza Comercial La Cachanilla, City Forest and Zoo and Juventud 2000 Sport Centre are among the big attractions worth exploring. A few quick clicks is all it takes to put together the perfect Santa Isabel holiday on Expedia.

Santa Isabel Essential Information

Language
Spanish
Currency
Mexican pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
General Rodolfo Sanchez Taboada Intl. Airport (MXL)
Population
29,300
Max Temp Winter
18ºC
Max Temp Summer
27ºC
Top Sights
City Forest and Zoo, Sol Childrens Museum and Eagles Nest Stadium

Top hotels in Santa Isabel

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

4 out of 5
Boulevard Benito Juarez 2151 Mexicali BC
Fully refundableReserve now, pay when you stay
The price is £94 per night from 12 Jul to 13 Jul
£94
12 Jul - 13 Jul
includes taxes & fees
9.2/10 Wonderful! (1,697 reviews)
"Great place to stay but something very annoying was that room key stopped working after 1 day and I was staying there for 2 nights, you cannot even call for help from the building , they should have emergency phones in the hallways instead of walking all the way to the lobby which is really far. ..."

Reviewed on 8 Jul 2026

Hotel Lucerna Mexicali
Hotel Araiza Mexicali

Hotel Araiza Mexicali

4 out of 5
Blvd. Benito Juarez 2220 Mexicali BC
Fully refundableReserve now, pay when you stay
The price is £93 per night from 16 Jul to 17 Jul
£93
16 Jul - 17 Jul
includes taxes & fees
8.8/10 Excellent! (1,849 reviews)
"Sólo que al hacer check in no estaba lista mi habitación pero me dieron una buena solución !!"

Reviewed on 6 Jul 2026

Hotel Araiza Mexicali
Calafia Hotel

Calafia Hotel

3.5 out of 5
1495 Justo Sierra, Fracc. Los Pinos Mexicali BC
The price is £58 per night from 23 Jul to 24 Jul
£58
23 Jul - 24 Jul
includes taxes & fees
8.4/10 Very good! (1,007 reviews)
"Excellent"

Reviewed on 10 Jul 2026

Calafia Hotel
See all 72 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santa Isabel travel package cost?
Get set to book, because a trip to Santa Isabel starts from an enticing . When you combine your flights, hotels and more into a package, you'll land the lowest prices.
If I'm not able to travel, can I cancel my Santa Isabel travel package?
You sure can, and we're here to help. You may be able to cancel and rebook your Santa Isabel travel package at no cost if you booked in the last 24 hours. But you may incur a fee from your hotel, airline or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, look up our Customer Service Portal for more information.
How do I get a cheap travel package to Santa Isabel?
You'll save tons of cash if you bundle your hotels, flights and car rentals into a Santa Isabel travel package. Sometimes cheap packages mean fewer choices. But not with Expedia. We offer over 550 partner airlines and 1,000,000 hotels all over the world, so you'll always have plenty of variety to choose from. Like to save even more? Add some interesting activities to your package deal and unlock even more bargains! After all, travel is about more than just getting to your destination.
Does Expedia offer Book Now, Pay Later Santa Isabel holidays?
Your bank balance shouldn't prevent you from taking a holiday, so Expedia has worked out a solution to help. Now that we've partnered with online lender Klarna, it's easier than ever to book a terrific getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the worry out of budgeting for your break. Check out these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna can help. Paying in easy monthly instalments will make your getaway dreams come true.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your trip over multiple transactions.
  • Low deposit holidays: When you come across an awesome deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you lock in your escape.

What are the top hotels in Santa Isabel?
If it's your very first time in Santa Isabel, make a reservation at Hotel Lucerna Mexicali or Real Inn Mexicali. Both offer comfy beds and are popular options with many savvy travellers.
How far in advance should I book my Santa Isabel holiday?
It can be hard to know exactly when the best time is to book your trip to Santa Isabel. But typically the earlier you book, the better the prices. Sometimes, you can lock in your flights and hotels up to 12 months prior to departure. If you're eager to escape on a last-minute getaway, no need to stress! There are incredible deals posted on Expedia every day.
What does an Expedia Santa Isabel travel package include?
Flights, hotels and a cool set of wheels for your road trip adventures. Simply choose your favourite bundle and get access to incredible deals. Once you've made your booking, add on some experiences and tours and watch your savings grow. When it comes to creating your Santa Isabel getaway, you're the boss!
What should I know before booking a Santa Isabel travel package?
So many places to venture to, so many things to experience. With a travel package, you can tick more of them off your list. Combine your hotels, flights and rental cars and score big savings.
Can I choose my airline with a Santa Isabel Expedia travel package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines throughout the world. Our packages give you the flexibility to take your pick of available flights, hotels and activities that fit your needs.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.