Title: Hotels in Santa Isabel do Rio Negro - Best Santa Isabel do Rio Negro Hotels from £16 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Isabel do Rio Negro](https://expedia.co.uk/Santa-Isabel-Do-Rio-Negro-Holiday-Rentals.d553248634664628244.Travel-Guide-HolidayRentals)[Santa Isabel do Rio Negro Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Isabel-Do-Rio-Negro.d553248634664628244.Car-Hire-Guide)[Santa Isabel do Rio Negro Holidays](https://expedia.co.uk/Santa-Isabel-Do-Rio-Negro.d553248634664628244.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [5 Feb - 6 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [6 Feb - 7 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Do-Rio-Negro-Hotels.d553248634664628244.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Do-Rio-Negro-Hotels.d553248634664628244.Travel-Guide-Hotels) ## Stay near popular Santa Isabel do Rio Negro attractions ### Pico da Neblina Commune with nature and explore the great outdoors at Pico da Neblina during your travels in Santa Isabel do Rio Negro. Discover the mountain views while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621562483867) ## Top Santa Isabel do Rio Negro Hotel Reviews ## More cheap stays in Santa Isabel do Rio Negro ![Hotel Manaus - Dom Pedro](https://images.trvl-media.com/lodging/94000000/93500000/93495000/93495000/f2784728_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Manaus - Dom Pedro R. Tomé de Souza 5 Manaus AM £16 6 Feb - 7 Feb includes taxes & fees 7.2/10 Good! (31 reviews) [](https://expedia.co.uk/Manaus-Hotels-Hotel-Manaus-Dom-Pedro.h93495000.Hotel-Information) ![Boutique Hotel Casa Teatro](https://images.trvl-media.com/lodging/5000000/4680000/4673500/4673440/c837d777_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Boutique Hotel Casa Teatro Rua 10 De Julho 632 - Centro Manaus AM £24 8 Feb - 9 Feb includes taxes & fees 7.6/10 Good! (125 reviews) [](https://expedia.co.uk/Manaus-Hotels-Boutique-Hotel-Casa-Teatro.h4673440.Hotel-Information) ![Casa Paraense ](https://images.trvl-media.com/lodging/116000000/115890000/115881300/115881233/b9be1971_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Paraense R. Valência, 16 Manaus AM £26 9 Feb - 10 Feb includes taxes & fees 8.6/10 Excellent! (25 reviews) [](https://expedia.co.uk/Manaus-Hotels-Casa-Paraense.h115881233.Hotel-Information) ![Anaconda Amazon Resort](https://images.trvl-media.com/lodging/45000000/44520000/44517000/44516991/72291a34_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Anaconda Amazon Resort Igarapé Jacaré Ubal, s/n, Zona Rural Manaus Amazonas £139 9 Feb - 10 Feb includes taxes & fees [](https://expedia.co.uk/Manaus-Hotels-Anaconda-Amazon-Resort.h44516991.Hotel-Information) ![Galeria & Hotel Farol da Barra](https://images.trvl-media.com/lodging/12000000/11760000/11750200/11750147/e79b5bbd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Galeria & Hotel Farol da Barra Rua Luiz Antony, 307 Manaus AM [Get rates](https://expedia.co.uk/Hotel-Search?startDate=19%2F02%2F2026&endDate=20%2F02%2F2026&selected=11750147&PinnedHotelID=11750147&HadPinnedHotel=true®ionId=553248634664628244) 8.2/10 Very Good! (25 reviews) [](https://expedia.co.uk/Manaus-Hotels-Galeria-Hotel-Farol-Da-Barra.h11750147.Hotel-Information) ![Tropical Executive Suit 1006](https://images.trvl-media.com/lodging/112000000/111160000/111153900/111153806/w1200h1060x0y0-bd1b6aa8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tropical Executive Suit 1006 1320 Avenida Coronel Teixeira Manaus AM [Get rates](https://expedia.co.uk/Hotel-Search?startDate=19%2F02%2F2026&endDate=20%2F02%2F2026&selected=111153806&PinnedHotelID=111153806&HadPinnedHotel=true®ionId=553248634664628244) 8/10 Very Good! (1 review) [](https://expedia.co.uk/Manaus-Hotels-Tropical-Executive-Residence-Hotel.h111153806.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa Isabel Do Rio Negro? > This central area is where most of the town's limited accommodation options are found. It's convenient for accessing the main docks, which are crucial for any river excursions or transfers. You'll find the primary shops, eateries, and local services concentrated here, making it easy to arrange logistics or grab essentials. > > > For travellers looking for a base before or after a fishing or jungle expedition, staying in this central area is ideal. It provides the most straightforward access to local guides and boats, which are essential for exploring the surrounding Amazon rainforest and its tributaries. ### When is the best time to go to Santa Isabel Do Rio Negro? > This period typically offers lower water levels in the rivers, making it ideal for fishing enthusiasts. The weather is generally sunny with less rainfall, which is more comfortable for outdoor activities and exploring the region. It's also when the water levels recede, allowing for easier navigation and access to various fishing spots. > > > For serious anglers, particularly those targeting specific species like peacock bass, the dry season is paramount. The lower water concentrates the fish, increasing the chances of a successful catch. Many fishing lodges and guided tours operate primarily during these months to maximise their guests' experience. > > > Couples looking for a more comfortable and predictable travel experience will also appreciate the dry season. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Isabel do Rio Negro hotel booking with Expedia? ### How much is the nightly rate at a Santa Isabel do Rio Negro hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - More ways to book - [Fonte Boa Hotels ](https://www.expedia.co.uk/Fonte-Boa-Hotels.d553248634762023259.Travel-Guide-Hotels) - [Flights from Manaus (MAO) to Sao Gabriel da Cachoeira (SJL) ](https://www.expedia.co.uk/lp/flights/mao/sjl/manaus-to-sao-gabriel-da-cachoeira) - [Book Hotels in Santa Isabel do Rio Negro on Expedia.com.br ](https://www.expedia.com.br/Santa-Isabel-Do-Rio-Negro-Hoteis.d553248634664628244.Guia-de-Hoteis) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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