Title: Hotels in Santa Isabel do Rio Negro - Best Santa Isabel do Rio Negro Hotels from £16 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Isabel do Rio Negro](https://expedia.co.uk/Santa-Isabel-Do-Rio-Negro-Holiday-Rentals.d553248634664628244.Travel-Guide-HolidayRentals)[Santa Isabel do Rio Negro Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Isabel-Do-Rio-Negro.d553248634664628244.Car-Hire-Guide)[Santa Isabel do Rio Negro Holidays](https://expedia.co.uk/Santa-Isabel-Do-Rio-Negro.d553248634664628244.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Isabel do Rio Negro from £16 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [7 Nov - 8 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2025-11-07&endDate=2025-11-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2025-11-08&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santa Isabel do Rio Negro hotels and places to stay ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Do-Rio-Negro-Hotels.d553248634664628244.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Do-Rio-Negro-Hotels.d553248634664628244.Travel-Guide-Hotels) ## Stay near popular Santa Isabel do Rio Negro attractions [](https://www.expedia.co.uk/Pico-Da-Neblina-Hotels.0-l553248621562483867-0.Travel-Guide-Filter-Hotels) ### Pico da Neblina Commune with nature and explore the great outdoors at Pico da Neblina during your travels in Santa Isabel do Rio Negro. Discover the mountain views while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621562483867) ## Top Santa Isabel do Rio Negro Hotel Reviews ## More cheap stays in Santa Isabel do Rio Negro ![Casa Paraense ](https://images.trvl-media.com/lodging/116000000/115890000/115881300/115881233/b9be1971_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Paraense R. Valência, 16, Manaus, AM £23 9 Nov - 10 Nov includes taxes & fees 8.6/10 Excellent! (14 reviews) [](https://expedia.co.uk/Manaus-Hotels-Casa-Paraense.h115881233.Hotel-Information) ![Boutique Hotel Casa Teatro](https://images.trvl-media.com/lodging/5000000/4680000/4673500/4673440/c837d777_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Boutique Hotel Casa Teatro Rua 10 De Julho 632 - Centro, Manaus, AM £29 14 Nov - 15 Nov includes taxes & fees 7.6/10 Good! (123 reviews) [](https://expedia.co.uk/Manaus-Hotels-Boutique-Hotel-Casa-Teatro.h4673440.Hotel-Information) ![Hotel Manaus - Dom Pedro](https://images.trvl-media.com/lodging/94000000/93500000/93495000/93495000/f2784728_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Manaus - Dom Pedro R. Tomé de Souza 5, Manaus, AM £16 16 Nov - 17 Nov includes taxes & fees 7.2/10 Good! (29 reviews) [](https://expedia.co.uk/Manaus-Hotels-Hotel-Manaus-Dom-Pedro.h93495000.Hotel-Information) ![Hotel Manaus - Dom Pedro l](https://images.trvl-media.com/lodging/104000000/103170000/103160600/103160562/c7bb190e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Manaus - Dom Pedro l R. Tomé de Souza, 5, Manaus, AM £24 12 Nov - 13 Nov includes taxes & fees 6.8/10 (17 reviews) [](https://expedia.co.uk/Manaus-Hotels-Hotel-Manaus-Dom-Pedro-L.h103160562.Hotel-Information) ![Flat em Tropical Executive Hotel](https://images.trvl-media.com/lodging/113000000/112290000/112286600/112286537/8a557902_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Flat em Tropical Executive Hotel Av. Coronel Teixeira, 1320, 103, Manaus, AM £46 1 Dec - 2 Dec includes taxes & fees 8/10 Very Good! (9 reviews) [](https://expedia.co.uk/Manaus-Hotels-Flat-Em-Tropical-Executive-Hotel.h112286537.Hotel-Information) ![Flat com vista no Tropical Executive ](https://images.trvl-media.com/lodging/113000000/112290000/112280800/112280718/65179542_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Flat com vista no Tropical Executive Av. Coronel Teixeira, 1320, 914, Manaus, AM £48 1 Dec - 2 Dec includes taxes & fees 7.8/10 Good! (11 reviews) [](https://expedia.co.uk/Manaus-Hotels-Flat-Com-Vista-No-Tropical-Executive.h112280718.Hotel-Information) ## Frequently asked questions ### If I need to cancel my hotel reservation in Santa Isabel do Rio Negro, will I receive a refund? > Yes! The majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you might be able to still cancel and be given a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santa Isabel do Rio Negro. ### What should I do while I'm visiting Santa Isabel do Rio Negro? > A favourite place to visit is [Pico da Neblina](https://www.expedia.co.uk/Pico-Da-Neblina-Santa-Isabel-do-Rio-Negro.d553248621562483867.Attraction). Take a look at what more there is to see and do in Expedia's [Santa Isabel do Rio Negro guide](https://www.expedia.co.uk/Santa-Isabel-Do-Rio-Negro.dx553248634664628244). ### What's the seasonal weather in Santa Isabel do Rio Negro? > The hottest months are usually September and October, with an average temperature of 27°C, while the coldest months are July and June, with an average of 26°C. The rainiest months in Santa Isabel do Rio Negro are May, April, March and June, with each month seeing an average of 407 mm of rainfall. ## Explore a world of travel with Expedia - Accommodation - Flights - More ways to book - [Fonte Boa Hotels](https://www.expedia.co.uk/Fonte-Boa-Hotels.d553248634762023259.Travel-Guide-Hotels) - [Flights from Manaus (MAO) to Sao Gabriel da Cachoeira (SJL)](https://www.expedia.co.uk/lp/flights/mao/sjl/manaus-to-sao-gabriel-da-cachoeira) - [Book Hotels in Santa Isabel do Rio Negro on Expedia.com.br](https://www.expedia.com.br/Santa-Isabel-Do-Rio-Negro-Hoteis.d553248634664628244.Guia-de-Hoteis) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)