Title: Hotels in Santa Isabel do Rio Negro - Best Santa Isabel do Rio Negro Hotels from £16 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Isabel do Rio Negro](https://expedia.co.uk/Santa-Isabel-Do-Rio-Negro-Holiday-Rentals.d553248634664628244.Travel-Guide-HolidayRentals)[Santa Isabel do Rio Negro Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Isabel-Do-Rio-Negro.d553248634664628244.Car-Hire-Guide)[Santa Isabel do Rio Negro Holidays](https://expedia.co.uk/Santa-Isabel-Do-Rio-Negro.d553248634664628244.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Isabel do Rio Negro from £16 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [22 Dec - 23 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248634664628244&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Do-Rio-Negro-Hotels.d553248634664628244.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Do-Rio-Negro-Hotels.d553248634664628244.Travel-Guide-Hotels) ## Stay near popular Santa Isabel do Rio Negro attractions ### Pico da Neblina Commune with nature and explore the great outdoors at Pico da Neblina during your travels in Santa Isabel do Rio Negro. Discover the mountain views while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621562483867) ## Top Santa Isabel do Rio Negro Hotel Reviews ## More cheap stays in Santa Isabel do Rio Negro ![Hotel Manaus - Dom Pedro](https://images.trvl-media.com/lodging/94000000/93500000/93495000/93495000/f2784728_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Manaus - Dom Pedro R. Tomé de Souza 5 Manaus AM £16 23 Dec - 24 Dec includes taxes & fees 7.2/10 Good! (31 reviews) [](https://expedia.co.uk/Manaus-Hotels-Hotel-Manaus-Dom-Pedro.h93495000.Hotel-Information) ![Casa Paraense ](https://images.trvl-media.com/lodging/116000000/115890000/115881300/115881233/b9be1971_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Paraense R. Valência, 16 Manaus AM £17 1 Jan - 2 Jan 2026 includes taxes & fees 8.6/10 Excellent! (21 reviews) [](https://expedia.co.uk/Manaus-Hotels-Casa-Paraense.h115881233.Hotel-Information) ![Boutique Hotel Casa Teatro](https://images.trvl-media.com/lodging/5000000/4680000/4673500/4673440/c837d777_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Boutique Hotel Casa Teatro Rua 10 De Julho 632 - Centro Manaus AM £26 23 Dec - 24 Dec includes taxes & fees 7.6/10 Good! (124 reviews) [](https://expedia.co.uk/Manaus-Hotels-Boutique-Hotel-Casa-Teatro.h4673440.Hotel-Information) ![Galeria & Hotel Farol da Barra](https://images.trvl-media.com/lodging/12000000/11760000/11750200/11750147/e79b5bbd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Galeria & Hotel Farol da Barra Rua Luiz Antony, 307 Manaus AM £27 23 Dec - 24 Dec includes taxes & fees 8.2/10 Very Good! (24 reviews) [](https://expedia.co.uk/Manaus-Hotels-Galeria-Hotel-Farol-Da-Barra.h11750147.Hotel-Information) ![Anaconda Amazon Resort](https://images.trvl-media.com/lodging/45000000/44520000/44517000/44516991/72291a34_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Anaconda Amazon Resort Igarapé Jacaré Ubal, s/n, Zona Rural Manaus Amazonas £135 23 Dec - 24 Dec includes taxes & fees [](https://expedia.co.uk/Manaus-Hotels-Anaconda-Amazon-Resort.h44516991.Hotel-Information) ![Tropical Executive Suit 1006](https://images.trvl-media.com/lodging/112000000/111160000/111153900/111153806/w1200h1060x0y0-bd1b6aa8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tropical Executive Suit 1006 1320 Avenida Coronel Teixeira Manaus AM [Get rates](https://expedia.co.uk/Hotel-Search?startDate=05%2F01%2F2026&endDate=06%2F01%2F2026&selected=111153806&PinnedHotelID=111153806&HadPinnedHotel=true®ionId=553248634664628244) 8/10 Very Good! (1 review) [](https://expedia.co.uk/Manaus-Hotels-Tropical-Executive-Residence-Hotel.h111153806.Hotel-Information) ## Frequently asked questions ### If I need to cancel my hotel reservation in Santa Isabel do Rio Negro, will I receive a refund? ### What should I do while I'm visiting Santa Isabel do Rio Negro? ### What's the seasonal weather in Santa Isabel do Rio Negro? ## Explore a world of travel with Expedia - Accommodation - Flights - More ways to book - [Fonte Boa Hotels ](https://www.expedia.co.uk/Fonte-Boa-Hotels.d553248634762023259.Travel-Guide-Hotels) - [Flights from Manaus (MAO) to Sao Gabriel da Cachoeira (SJL) ](https://www.expedia.co.uk/lp/flights/mao/sjl/manaus-to-sao-gabriel-da-cachoeira) - [Book Hotels in Santa Isabel do Rio Negro on Expedia.com.br ](https://www.expedia.com.br/Santa-Isabel-Do-Rio-Negro-Hoteis.d553248634664628244.Guia-de-Hoteis) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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