Santa Isabel do Rio Negro Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Santa Isabel do Rio Negro Essential Information

Language
Portuguese
Currency
Brazilian reals
Local Welcome
Olá
Local Goodbye
Adeus
Max Temp Winter
32ºC
Max Temp Summer
32ºC

Top hotels in Santa Isabel do Rio Negro

Hotel Intercity Manaus

Hotel Intercity Manaus

4 out of 5
Rua Professor Marciano Armond, 544 Manaus AM
The price is £51 per night from 15 Nov to 16 Nov
£51
15 Nov - 16 Nov
includes taxes & fees
Hotel Intercity Manaus
Hotel Express Vieiralves

Hotel Express Vieiralves

3 out of 5
Rua Rio Branco, s/n Manaus AM
Fully refundableReserve now, pay when you stay
The price is £29 per night from 8 Nov to 9 Nov
£29
8 Nov - 9 Nov
includes taxes & fees
8.6/10 Excellent! (1,003 reviews)
"Nice breakfast and restaurant"

Reviewed on 24 Sept 2026

Hotel Express Vieiralves
Da Vinci Hotel & Conventions by Easy Hotéis

Da Vinci Hotel & Conventions by Easy Hotéis

4 out of 5
Rua Belo Horizonte, 240A - Adrianopolis Manaus AM
Fully refundableReserve now, pay when you stay
The price is £40 per night from 6 Dec to 7 Dec
£40
6 Dec - 7 Dec
includes taxes & fees
8.2/10 Very good! (375 reviews)
"There was rouches.in the room"

Reviewed on 6 Nov 2026

Da Vinci Hotel & Conventions by Easy Hotéis
See all 301 properties in Amazonas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular Santa Isabel do Rio Negro attractions

Pico da Neblina

Commune with nature and explore the great outdoors at Pico da Neblina during your travels in Santa Isabel do Rio Negro. Discover the mountain views while you're in the area.
See properties

Frequently asked questions

How much does a Santa Isabel do Rio Negro travel package cost?
Live it up in Santa Isabel do Rio Negro from as low as . We offer a great selection of flights, rental cars and hotels to suit every budget and style. Land even better deals when you add some activities or tours to your package.
If I'm not able to travel, can I cancel my Santa Isabel do Rio Negro travel package?
Because we know life is full of surprises, the answer is yes. For more information, head to our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it without penalty. Your airline, hotel or car rental company may charge a fee if you made your booking a while ago.
How do I get a cheap travel package to Santa Isabel do Rio Negro?
Creating your own Santa Isabel do Rio Negro travel package with Expedia is a great way to save. We offer access to over 550 air carriers and 1,000,000 properties across the globe. With such a fabulous range to pick from, you'll have no trouble pulling together your ideal holiday.
Does Expedia offer Book Now, Pay Later Santa Isabel do Rio Negro holidays?
Expedia has partnered with online lender Klarna to make booking your next break easier on your budget. Paying by instalment means you can spread the costs of your next adventure, leaving you with more cash to play with while you're away. Klarna has several payment plans to choose from, so you're sure to find one that fits your budget. Check out these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month is what works best for you, Klarna can help. Paying in easy monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay off your holiday over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to click that "book now" button, go for a low deposit holiday payment plan with Klarna.

What are the top hotels in Santa Isabel do Rio Negro?
Get your escape off to a good start by booking a room at Go Inn Manaus. It's one of most sought-after hotels in Santa Isabel do Rio Negro. Another cosy option is ibis Manaus Aeroporto.
How far in advance should I book my Santa Isabel do Rio Negro holiday?
To score discount prices, book nice and early. Air carriers generally advertise flight tickets, along with some of the lowest fares, up to 12 months ahead of time. Hotels, experiences and car rental should also be booked early to avoid disappointment. If you've decided on a last-minute getaway to Santa Isabel do Rio Negro, there are always plenty of great deals to be had on Expedia. Book your escape today!
What does an Expedia Santa Isabel do Rio Negro travel package include?
Flights, rental cars and hotels, or any combination of the three — it's your choice. Whether you're visiting Santa Isabel do Rio Negro with the entire family or travelling solo, there's a bundle to match every style and budget. Once you've made your booking, why not add on a couple of activities?
What should I know before booking a Santa Isabel do Rio Negro travel package?
So many places to wander around, so many things to do. With a package, you can check more of them off your list. Combine your flights, rental cars and hotels and make big savings.
Can I choose my airline with a Santa Isabel do Rio Negro Expedia travel package?
Yes, so take your pick! We have access to over 550 airlines around the world, so you can design your Santa Isabel do Rio Negro getaway according to your budget and style.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.