Hotels in Santa Fe, FL - Best Santa Fe Hotels from £40 - Fully Refundable Options

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Our top choices for Santa Fe hotels

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

A reception desk with a "Welcome to the Sun Shine State" sign, a "Treats" sign, and a minibar area with a "Hilton" sign.

1. Hampton Inn & Suites Alachua I-75

Alachua

Jasmine

£88

includes taxes & fees

13 Sept - 14 Sept

A clean, modern cafe with a marble floor, a counter with coffee machines, and a clock on the wall.

A workspace with two chairs, a desk, a computer monitor, and a wall-mounted sign reading 'BUSINESS CENTER'.

A corner of a store with shelves stocked with snacks, beverages, and a refrigerated display case.

A two-story motel with a covered entrance, a parking lot, and a clear sky.

2. Clarion Pointe Alachua - Gainesville Area

Alachua

YESSICA

£52

includes taxes & fees

7 Sept - 8 Sept

A spacious indoor dining area with multiple tables and chairs, large windows offering a view of palm trees and greenery outside.

A hotel room with a bed, a desk with a chair, a television, and a blue sofa.

A Holiday Inn Express & Suites hotel with a modern design, multiple floors, and a parking lot.

A lobby with a patterned carpet, two green armchairs, a white sofa, a small round table with a plant, and framed artwork on the wall.

3. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Alachua

Tobias

£83

includes taxes & fees

6 Oct - 7 Oct

A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.

A hotel room with a bed, a desk with a chair, a television, a mirror, and a wardrobe.

A spacious lobby with a dining area, a kitchen, and a large window providing a view of the outdoors.

A reception desk with a sign reading "Quality by Choice Hotels," surrounded by various reptile decorations.

4. Quality Inn Alachua - Gainesville Area

Alachua

Courtney

£63

includes taxes & fees

27 Sept - 28 Sept

A large, multi-story hotel with a central courtyard, palm trees, and an American flag.

A spacious lobby with a large painting, a fireplace, a piano, and multiple seating areas.

A bar area with wooden chairs, a bar counter, and a television mounted on the wall.

A spacious dining area with multiple tables and chairs, a kitchen area with a coffee station, and large windows allowing natural light.

5. Best Western Gateway Grand

Gainesville

Ammarica

£70

includes taxes & fees

13 Sept - 14 Sept

A stone water feature with cascading water, surrounded by a brick wall and greenery.

A spacious living area with a wooden floor, a blue sofa, a round coffee table, and a ceiling fan.

A covered outdoor area with a paved walkway leading to a seating area, surrounded by greenery and a clear sky.

A neatly arranged bedroom with a bed, bedside lamps, a TV, and a mirror.

6. BlueGem Motel

High Springs

REINIER

£73

includes taxes & fees

15 Sept - 16 Sept

A room with a wooden ceiling, two beds with patterned bedding, a desk, and a chair.

A row of motel buildings with a fire hydrant and trees in front.

A stone outdoor seating area with a table and benches, a trash bin, and a building in the background.

A bedroom with a bed, a chair, a dresser, a ceiling fan, a window with blinds, and a wall-mounted air conditioner.

7. High Springs Country Inn

High Springs

Antonio

£51

includes taxes & fees

15 Sept - 16 Sept

A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.

A living room with a grey sofa, a wooden coffee table, and a framed horse picture on the wall.

A kitchen with a green refrigerator, a wooden countertop, a black kettle, and a wooden cutting board.

8. Vista Verde Farm Retreat

Lake City

Stacy

£146

includes taxes & fees

13 Sept - 14 Sept

A cabin with a cozy interior, a dining area, and a view of the forest.

A cozy cabin interior with a wooden interior, a dining table with a chair, a window, and a hanging lantern.

A bedroom with a wooden headboard, a bed with white linens, a window with a view of green foliage, and a tray with breakfast items.

9. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

High Springs

Keren

£170

includes taxes & fees

7 Sept - 8 Sept

A hotel room with two beds, a desk, a chair, and a television.

A parking lot with marked lanes and a grassy area on one side.

A motel with a two-story structure, a covered front entrance, and a parking lot with several cars.

A bathroom with a white sink, mirror, and towel rack.

10. Royal Inn

Alachua

Alec

£60

includes taxes & fees

7 Sept - 8 Sept

A hotel room with a bed, bedside tables, a desk, a chair, a mirror, and a window.

A reception area with a counter, a computer, and a bulletin board with pamphlets.

A building with a Coca-Cola vending machine, a window with a 'OPEN' sign, and a red awning.

A bathroom with a large mirror, a sink, and a towel rack.

11. Palms Garden Inn

Lake City

Caroline

£54

includes taxes & fees

7 Oct - 8 Oct

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.

A modern lounge area with a flat-screen TV, a fireplace, teal and brown seating, patterned carpet, and a wall-mounted clock.

A modern kitchen with blue-tiled walls, stainless steel appliances, and a central island.

A hotel reception area with directional signs for elevators, floor 1, pool restrooms, and business center.

12. La Quinta by Wyndham Gainesville

Gainesville

Riesha

£79

includes taxes & fees

8 Sept - 9 Sept

A hotel room with two beds, a desk, a chair, a television, and a bathroom visible through an open door.

A hotel dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and a patterned carpet.

A hotel room with a carpeted floor, a desk with a lamp, two yellow armchairs, a sofa, and a television.

A reception area with a dark wooden reception desk, a large white floral wall art, and a tiled floor.

13. Days Inn by Wyndham Gainesville University I-75

Gainesville

Misty

£60

includes taxes & fees

8 Sept - 9 Sept

A modern kitchen with dark cabinets, stainless steel appliances, and a wooden ceiling.

A modern building with a unique facade featuring a grid of colorful panels.

A porch with two Adirondack chairs, a wooden door, and a sign reading "Downtown Studio Depot Village".

A staircase with dark wooden steps leading to a landing with a small table and chair.

14. Depot Village

Gainesville

Trisha

£99

includes taxes & fees

7 Sept - 8 Sept

A swimming pool with a metal ladder, surrounded by a white fence and green chairs.

A living room with a curved sofa, a wooden cabinet, and a fish tank.

A hotel room with a patterned carpet, a sofa, a small table, a lamp, and a door with a notice.

A refrigerated display case with beverages and snacks, and a shelf with bottled water and other beverages.

15. Best Western Waldo Inn and Suites

Waldo

Ana Laura

£85

includes taxes & fees

7 Sept - 8 Sept

An outdoor patio with wicker furniture, stone walls, and a barbecue grill.

A modern dining area with a wooden table, blue upholstered chairs, and pendant lighting.

TownePlace Suites Marriott with a modern exterior, multiple windows, and a covered entrance area.

A modern hotel room with a flat-screen TV, a dining area with a table and chairs, a kitchenette, and a wardrobe with hanging space.

16. TownePlace Suites by Marriott Gainesville Northwest

Gainesville

Tanya

£87

includes taxes & fees

8 Sept - 9 Sept

A hotel room with a large bed, a nightstand, a chair, a window with a view of greenery, and a beach-themed wall mural.

A Days Inn by Wyndham hotel with a blue awning, large windows, and a parking lot.

A reception area with a Days Inn sign, a reception desk, a blue couch, and a plant.

17. Days Inn by Wyndham Gainesville Hospital/University Area

Gainesville

Christy

£54

includes taxes & fees

7 Sept - 8 Sept

A modern building entrance with a covered entrance area, glass doors, and surrounding greenery.

A hotel lobby with a reception desk, seating area, and a view of the dining area.

A hotel room with a grey sofa, a small table, a desk, a chair, and a large window with curtains.

A hotel room with a grey sofa, a small table, a lamp, a framed picture on the wall, and a bed with a blue blanket.

18. Comfort Inn Gainesville - University Area

Gainesville

Jyothi

£67

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a bed, two bedside tables with lamps, a large bathtub, and green walls.

A breakfast bar with a juice dispenser, cereal boxes, and fruit bowls.

A Sleep Inn & Suites building with a clear entrance, a covered waiting area, and a parking lot.

A hotel room with two beige armchairs, a small side table, a glass display cabinet with sports memorabilia, a mounted flat-screen TV, and a door with a wooden frame.

19. Sleep Inn & Suites University/Shands

Gainesville

prakasa Babu

£67

includes taxes & fees

5 Oct - 6 Oct

A multi-story hotel with a central entrance, palm trees, and a clear sky.

A hotel room with a bed, a desk, a television, a sofa, and artwork on the wall.

A modern living room with a green sofa, a round coffee table, and a fireplace.

A spacious hotel lobby with a modern staircase, a seating area with a sofa and chairs, and a dining area in the background.

20. Country Inn & Suites by Radisson, Gainesville, FL

Gainesville

Henry

£72

includes taxes & fees

13 Sept - 14 Sept

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Top Santa Fe Hotel Reviews

La Quinta by Wyndham Gainesville

10/10 Excellent

"Breakfast was so good. Clean rooms and so close to campus it worked out perfectly. We will definitely stay again when we come down."

Hotel Indigo Gainesville-Celebration Pointe by IHG

8/10 Good

"Sería bueno si incluyeran el desayuno"

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"👍👍"

Sleep Inn & Suites University/Shands

10/10 Excellent

"Very accommodating staff. We got there before check in and they gave us a different room without question. They had popcorn and cookies available for free too which was great! The breakfast was alright. Small selection but didnt expect much given the small scale of the hotel. The shower had some hair in it that wasnt ours... but overall a decent stay"

More cheap stays in Santa Fe

Days Inn by Wyndham Gainesville Hospital/University Area

2649 Sw 13th St Gainesville FL

£54

7 Sept - 8 Sept

includes taxes & fees

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter Gainesville FL

£60

8 Sept - 9 Sept

includes taxes & fees

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL

£64

13 Sept - 14 Sept

includes taxes & fees

8.6/10 Excellent! (2,103 reviews)

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL

£67

5 Oct - 6 Oct

includes taxes & fees

8.8/10 Excellent! (1,295 reviews)

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL

£67

13 Sept - 14 Sept

includes taxes & fees

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL

£71

4 Oct - 5 Oct

includes taxes & fees

Frequently asked questions

What's the best place for a stay in Santa Fe?

Located 18.6 mi (30 km) from the heart of Santa Fe, Drury Inn & Suites Gainesville is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Country Inn & Suites by Radisson, Gainesville, FL and Hotel Eleo at the University of Florida. See all available top hotels, or vacation rentals in Santa Fe.

What are some of the best holiday rentals that Santa Fe has to offer?

Underwater Home w/Game Room ~6 min to Stadium & DT: This holiday home rental outside of Santa Fe is located in the city centre, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in Santa Fe.

If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.

What is staying in Santa Fe like?

Travellers to Santa Fe will find plenty to explore and enjoy. There are 794 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.

What is there to see in Santa Fe?

Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park and Devil's Milhopper Geological State Park. You'll also find Gainesville Raceway and Ruth B. Kirby Gilchrist Blue Springs State Park in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.

What's the weather like in Santa Fe?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.

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Find hotels in Santa Fe, FL from £40

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Fe

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Fe hotels

1. Hampton Inn & Suites Alachua I-75

2. Clarion Pointe Alachua - Gainesville Area

3. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

4. Quality Inn Alachua - Gainesville Area

5. Best Western Gateway Grand

6. BlueGem Motel

7. High Springs Country Inn

8. Vista Verde Farm Retreat

9. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10. Royal Inn

11. Palms Garden Inn

12. La Quinta by Wyndham Gainesville

13. Days Inn by Wyndham Gainesville University I-75

14. Depot Village

15. Best Western Waldo Inn and Suites

16. TownePlace Suites by Marriott Gainesville Northwest

17. Days Inn by Wyndham Gainesville Hospital/University Area

18. Comfort Inn Gainesville - University Area

19. Sleep Inn & Suites University/Shands

20. Country Inn & Suites by Radisson, Gainesville, FL

Top Santa Fe Hotel Reviews

La Quinta by Wyndham Gainesville

Hotel Indigo Gainesville-Celebration Pointe by IHG

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Sleep Inn & Suites University/Shands

More cheap stays in Santa Fe

Days Inn by Wyndham Gainesville Hospital/University Area

Days Inn by Wyndham Gainesville University I-75

HOM Hotel Gainesville, SureStay Collection by Best Western

Sleep Inn & Suites University/Shands

Comfort Inn Gainesville - University Area

Comfort Suites Gainesville near University

Frequently asked questions

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