Title: Hotels in Santa Fe, FL - Best Santa Fe Hotels from £42 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Fe](https://expedia.co.uk/Santa-Fe-Holiday-Rentals.d553248635975870004.Travel-Guide-HolidayRentals)[Santa Fe Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe.d553248635975870004.Car-Hire-Guide)[Santa Fe Holidays](https://expedia.co.uk/Santa-Fe.d553248635975870004.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Fe Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=POOL) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&lodging=APART_HOTEL) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=PETS) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&lodging=APARTMENT) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=HOT_TUB) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&lodging=CABIN) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&travelerType=family_friendly) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&lodging=COTTAGE) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&lodging=CONDO) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Fe%2C+Florida%2C+United+States+of+America®ionId=553248635975870004&latLong=29.883575%2C-82.430391&adults=2&startDate=2026-02-01&d1=2026-02-01&endDate=2026-02-03&d2=2026-02-03&amenities=WATER_PARK) ## Check prices for these dates Tonight [18 Jan - 19 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975870004&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Jan - 20 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975870004&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975870004&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975870004&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Fe hotels ![Free daily full breakfast ](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/baab3408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Free WiFi](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/098782ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/8ccd2f93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/91000000/90150000/90143200/90143200/eea1d68b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Starke by IHG [](https://www.expedia.co.uk/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information) Starke 9.6/10 Exceptional (453 reviews) "Incredible breakfast, large room, comfy bed, sparkling clean bathroom-all for an economical price!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Myrom £89 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Starke-Hotels-Holiday-Inn-Express-Starke.h90143200.Hotel-Information) ![Standard Double Room | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/ab06a2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/70c2cd09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/ebc25a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Single Room | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/124000000/123750000/123741900/123741815/f4ca4c49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Soho Inn Waldo [](https://www.expedia.co.uk/Waldo-Hotels-Soho-Inn-Waldo.h123741815.Hotel-Information) Waldo 7.6/10 Good (4 reviews) "Clean rooms ,checking in and out was a breeze,24 hour check in and on site Property manager.Simple Clean updated rooms with comfortable mattresses Great for a overnight stay or a weekend visit Rick the PM is a great guy and will ensure you are well situated " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glenn £59 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Waldo-Hotels-Soho-Inn-Waldo.h123741815.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/a1a33286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/b54c320d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/5ca419d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2390000/2384400/2384393/894b95a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Waldo Inn and Suites [](https://www.expedia.co.uk/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) Waldo 8.8/10 Excellent (958 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cathy £86 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Best-Western-Waldo-Inn-And-Suites.h2384393.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/0dff4e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/19713bd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/e93e0d3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/57b6c63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) Gainesville 9.6/10 Exceptional (1,340 reviews) "Enjoyable stay. Friendly staff and a clean comfortable ho Ted el" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CHARLES £88 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/e387508a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/w2878h1920x0y0-ae7e9910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/9c03edaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1289100/1289043/cf87e7bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Gainesville, FL [](https://www.expedia.co.uk/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) Gainesville 9.2/10 Wonderful (1,655 reviews) "Staff was great, breakfast was fantastic and check in was easy. I would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £78 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Country-Inn-Suites-By-Radisson.h1289043.Hotel-Information) ![Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/70ccd44a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/f7f29b03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/cba0289f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/d8c6de93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites University/Shands [](https://www.expedia.co.uk/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) Gainesville 8.8/10 Excellent (1,075 reviews) "Excellent location. Very nice staff. Rooms are clean. Love that they have complimentary coffee, popcorn and cookies in the main lobby." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessenia £71 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/0d00e88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/33d3a427.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/a3709b54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/79000000/78550000/78547700/78547624/efa545ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Gainesville Downtown [](https://www.expedia.co.uk/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information) Downtown Gainesville 9.2/10 Wonderful (1,116 reviews) "Nice place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stefanie £80 includes taxes & fees 21 Jan - 22 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Hyatt-Place-Gainesville-Downtown.h78547624.Hotel-Information) ![Luxury Apartment, 2 Bedrooms, Lanai, Courtyard View | Private kitchen | Mini-fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/02abb060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Studio, 1 Queen Bed, Kitchen, City View | Living area | 40-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/e1175056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Studio Suite, 1 Queen Bed, Patio, Courtyard Area | Bathroom | Shower, free toiletries, towels, soap](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/39089dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/93000000/92540000/92535400/92535326/w997h664x0y3-a53eaa50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Depot Village [](https://www.expedia.co.uk/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information) Gainesville 9.6/10 Exceptional (79 reviews) "The cleanest room I have seen in years an amazing place to stay amazing people coffee shop on site perfect for a little getaway with downtown close by." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan £80 includes taxes & fees 20 Jan - 21 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Depot-Village.h92535326.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/cc5c3b00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/bab33319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/bc49fa4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn University [](https://www.expedia.co.uk/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) Gainesville 8.2/10 Very good (1,025 reviews) "Been nice staying here" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £72 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/95cd6e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/d62bb37b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/9f7e63bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed, Non Smoking | Premium bedding, memory-foam beds, desk, laptop workspace](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/88194727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Gainesville near University [](https://www.expedia.co.uk/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information) Gainesville 9.2/10 Wonderful (1,199 reviews) "Awesome stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maricarmen £79 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760006/d9964af7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760006/c4df473c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760006/7954b6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/38000000/37770000/37760100/37760006/5e8d5ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta by Wyndham Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-La-Quinta-By-Wyndham-Gainesville.h37760006.Hotel-Information) Gainesville 9.0/10 Wonderful (1,155 reviews) "Very clean hotel and the breakfast was outstanding. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £96 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-La-Quinta-By-Wyndham-Gainesville.h37760006.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/8a6fa57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking (Larger Room) | Premium bedding, desk, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/f246ff96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/2f0849f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/4e0d3764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOM Hotel Gainesville, SureStay Collection by Best Western [](https://www.expedia.co.uk/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) Gainesville 8.4/10 Very good (1,816 reviews) "Awesome place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aristeo £63 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/1d4a6615.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/2dd8879c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/68371972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/65000000/64480000/64474900/64474824/847fac5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Alachua I-75 [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information) Alachua 9.4/10 Exceptional (479 reviews) "Good overnight experience on a car trip. Nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis £88 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Suites-Alachua-I-75.h64474824.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/f6ecaf62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking, Balcony | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/db000e55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/9a241e09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Hot Tub (Living Room;with Sofabed) | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/88146972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Gateway Grand [](https://www.expedia.co.uk/Gainesville-Hotels-Best-Western-Gateway-Grand.h151041.Hotel-Information) Gainesville 8.6/10 Excellent (1,392 reviews) "The entire hotel was super clean. The staff were all very helpful and friendly. Best hotel that I have been to in a long time. Highly recommend a stay there." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice £79 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Best-Western-Gateway-Grand.h151041.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/5b4e3b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Accessible (Roll-In Shower, Smoke Free) | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/16dba0bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/0a8e44cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/10598cf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn PLUS+ Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information) Gainesville 7.4/10 Good (1,240 reviews) "Just drove through and needed a place to stay seems decent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jordan £55 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/5b1d647e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Queen Bed (View) | Private kitchen | Mini-fridge, stovetop, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/1c1536fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/300e501a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110500000/110494400/110494372/4d166159.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy [](https://www.expedia.co.uk/High-Springs-Hotels-Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information) High Springs 10/10 Exceptional (166 reviews) "We had such a great time, the cabin was nice and clean and had everything you might need. We loved the little detail of the handwritten postcard and map! The fireplace area was so nice too, perfect for a little getaway! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ellie £142 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/High-Springs-Hotels-Postcard-Cabins-Gilchrist-Springs.h110494372.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23000/22999/74bc23f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23000/22999/9dd5a677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23000/22999/63cbaceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23000/22999/0bd1e264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Gainesville.h22999.Hotel-Information) Gainesville 8.8/10 Excellent (1,004 reviews) "The checkin staff was wonderful, welcoming me back from my last stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) SanJuana £80 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Gainesville.h22999.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/1560249f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/7d49c4d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/f7e7d47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1631400/1631322/fb54565b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Hilton-Garden-Inn-Gainesville.h1631322.Hotel-Information) Gainesville 8.8/10 Excellent (1,002 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adriana £79 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Hilton-Garden-Inn-Gainesville.h1631322.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/e851cfaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/a1c39a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds (Walk-In Shower) | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/578d088f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/23000000/22860000/22858300/22858269/758be2b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Alachua - Gainesville Area by IHG [](https://www.expedia.co.uk/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information) Alachua 9.4/10 Exceptional (1,005 reviews) "Great stay. Good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bob £97 includes taxes & fees 22 Jan - 23 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Holiday-Inn-Express-Suites-Alachua-Gainesville-Area.h22858269.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1210da70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/c37dfd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/3cda58a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439800/439799/1c3421f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Gainesville I-75 Hospital University Area [](https://www.expedia.co.uk/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information) Gainesville 7.4/10 Good (1,004 reviews) "Hotel is quiet . Check in was easy and staff was courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) calum £42 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville.h439799.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=553248635975870004&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Hotels.d553248635975870004.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-Hotels.d553248635975870004.Travel-Guide-Hotels) ## Top Santa Fe Hotel Reviews ![DoubleTree by Hilton Gainesville](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg) ### DoubleTree by Hilton Gainesville 10/10 Excellent "Nice room" [](https://expedia.co.uk/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![Best Western Gateway Grand](https://images.trvl-media.com/lodging/1000000/160000/151100/151041/9a241e09_y.jpg) ### Best Western Gateway Grand 10/10 Excellent "Very clean rooms and courteous staff. The breakfast buffet with the omelette station is amazing! " [](https://expedia.co.uk/Gainesville-Hotels-Best-Western-Gateway-Grand.h151041.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg) ### Sleep Inn & Suites University/Shands 10/10 Excellent "Only good things to say about this hotel. Outstanding service. Kudos to the staff. " [](https://expedia.co.uk/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85_y.jpg) ### Comfort Inn University 10/10 Excellent "Been nice staying here" [](https://expedia.co.uk/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ![Drury Inn & Suites Gainesville](https://images.trvl-media.com/lodging/20000000/19490000/19484600/19484503/93f8f773_y.jpg) ### Drury Inn & Suites Gainesville 10/10 Excellent "Clean and comfortable room with a great complimentary breakfast. We also enjoyed the happy hour when we arrived." [](https://expedia.co.uk/Gainesville-Hotels-Drury-Inn-Suites-Gainesville.h19484503.Hotel-Information) ![Hotel Indigo Gainesville-Celebration Pointe by IHG](https://images.trvl-media.com/lodging/27000000/26950000/26940800/26940780/dfb2f417_y.jpg) ### Hotel Indigo Gainesville-Celebration Pointe by IHG 10/10 Excellent "A1" [](https://expedia.co.uk/Gainesville-Hotels-Hotel-Indigo-Gainesville-Celebration-Pointe.h26940780.Hotel-Information) ![Hotel Eleo at the University of Florida](https://images.trvl-media.com/lodging/53000000/52060000/52054200/52054135/180700a0_y.jpg) ### Hotel Eleo at the University of Florida 10/10 Excellent "Stayed for one night, our room was clean and comfortable, the valet and front desk staff were very nice and friendly. Would stay again for sure." [](https://expedia.co.uk/Gainesville-Hotels-Hotel-Eleo-At-The-University-Of-Florida.h52054135.Hotel-Information) ![SpringHill Suites by Marriott Gainesville](https://images.trvl-media.com/lodging/2000000/1540000/1531600/1531530/6fa20102_y.jpg) ### SpringHill Suites by Marriott Gainesville 10/10 Excellent "This was a very nice place to stay, room was clean and well stocked. All the staff was very pleasant and had a very nice breakfast. Would highly recommend staying here." [](https://expedia.co.uk/Gainesville-Hotels-SpringHill-Suites-By-Marriott-Gainesville.h1531530.Hotel-Information) ![Hilton University of Florida Conference Center Gainesville](https://images.trvl-media.com/lodging/1000000/480000/475300/475205/7dbdcf15_y.jpg) ### Hilton University of Florida Conference Center Gainesville 10/10 Excellent "Room was good, friendly staff and the restaurants and bar at hotel is very convenient " [](https://expedia.co.uk/Gainesville-Hotels-Hilton-University-Of-Florida-Conference-Center-Gainesville.h475205.Hotel-Information) ## More cheap stays in Santa Fe ![Days Inn by Wyndham Gainesville University I-75](https://images.trvl-media.com/lodging/1000000/20000/19600/19555/d3372ae4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Gainesville University I-75 920 Nw 69th Ter Gainesville FL £54 21 Jan - 22 Jan includes taxes & fees 5.4/10 (1,000 reviews) [](https://expedia.co.uk/Gainesville-Hotels-Days-Inn-By-Wyndham-Gainesville-University-I-75.h19555.Hotel-Information) ![Red Roof Inn PLUS+ Gainesville](https://images.trvl-media.com/lodging/1000000/90000/82700/82677/5b4e3b0e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn PLUS+ Gainesville 3500 Southwest 42nd St Gainesville FL £55 25 Jan - 26 Jan includes taxes & fees 7.4/10 Good! (1,239 reviews) [](https://expedia.co.uk/Gainesville-Hotels-Red-Roof-Inn-PLUS-Gainesville.h82677.Hotel-Information) ![HOM Hotel Gainesville, SureStay Collection by Best Western](https://images.trvl-media.com/lodging/1000000/210000/200800/200755/07c3ba53_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOM Hotel Gainesville, SureStay Collection by Best Western 3905 Sw 43Rd St Gainesville FL £63 25 Jan - 26 Jan includes taxes & fees 8.4/10 Very Good! (1,808 reviews) [](https://expedia.co.uk/Gainesville-Hotels-HOM-Hotel-Gainesville.h200755.Hotel-Information) ![Sleep Inn & Suites University/Shands](https://images.trvl-media.com/lodging/2000000/1940000/1932400/1932346/3c8617a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn & Suites University/Shands 4110 SW 40th Boulevard Gainesville FL £71 8 Feb - 9 Feb includes taxes & fees 8.6/10 Excellent! (1,068 reviews) [](https://expedia.co.uk/Gainesville-Hotels-Sleep-Inn-Suites-UniversityShands.h1932346.Hotel-Information) ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/800000/793600/793525/78ca2e85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn University 3440 SW 40th Blvd Gainesville FL £72 1 Feb - 2 Feb includes taxes & fees 8.2/10 Very Good! (1,023 reviews) [](https://expedia.co.uk/Gainesville-Hotels-Comfort-Inn-University.h793525.Hotel-Information) ![Comfort Suites Gainesville near University](https://images.trvl-media.com/lodging/55000000/54140000/54138200/54138132/d62bb37b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Gainesville near University 2603 SW 13TH STREET Gainesville FL £79 25 Jan - 26 Jan includes taxes & fees 9/10 Wonderful! (1,199 reviews) [](https://expedia.co.uk/Gainesville-Hotels-Comfort-Suites-Gainesville.h54138132.Hotel-Information) ## Frequently asked questions ### What's the best place for a stay in Santa Fe? ### What are some of the best holiday rentals that Santa Fe has to offer? ### If I need to cancel my hotel reservation in Santa Fe, will I receive a refund? ### What is staying in Santa Fe like? ### What is there to see in Santa Fe? ### What's the weather like in Santa Fe? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [B&B in Alachua ](https://www.expedia.co.uk/Alachua-Bed-And-Breakfasts.d5933-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Alachua Hotels ](https://www.expedia.co.uk/Alachua-Hotels.d5933.Travel-Guide-Hotels) - [Archer Hotels ](https://www.expedia.co.uk/Archer-Hotels.d6352166.Travel-Guide-Hotels) - [Hilton Hotels in Brooker ](https://www.expedia.co.uk/Brooker-Hotels-Hilton-Hotels.0-0-d6352173--bHiltonHotels.Travel-Guide-Filter-Hotels) - 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