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Our top choices for Santa Fe hotels

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (530 reviews)
"Facility was very clean and breakfast was very good. Would definitely stay again. "
United States
Sheila
The price is £97
includes taxes & fees
10 May - 11 May
Holiday Inn Express Starke by IHG

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
Waldo
8.8 out of 10, Excellent, (988 reviews)
"The room was very nice and the staff was excellent "
United States
Brian
The price is £85
includes taxes & fees
4 May - 5 May
Best Western Waldo Inn and Suites

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,432 reviews)
"Great place to stay! Would recommend. "
United States
Michelle
The price is £92
includes taxes & fees
26 Apr - 27 Apr
Drury Inn & Suites Gainesville

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,313 reviews)
"Was a very clean place. Enjoyed the stay !"
United States
Robert
The price is £86
includes taxes & fees
26 Apr - 27 Apr
Comfort Suites Gainesville near University

La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (1,199 reviews)
"Clean rooms, staff really friendly "
Canada
Marc
The price is £85
includes taxes & fees
23 Apr - 24 Apr
La Quinta by Wyndham Gainesville

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1,764 reviews)
"Great hotel to stay!!!"
United States
Matthew S. Higgins
The price is £81
includes taxes & fees
26 Apr - 27 Apr
Country Inn & Suites by Radisson, Gainesville, FL

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,183 reviews)
"Breakfast was good , staff was friendly, parking was always available, the room was spacious and clean ."
United States
James
The price is £73
includes taxes & fees
26 Apr - 27 Apr
Sleep Inn & Suites University/Shands

Sweetwater Branch Inn

Sweetwater Branch Inn
3.5 star property
Gainesville
9.6 out of 10, Exceptional, (1,000 reviews)
"I loved this place! It was a perfect location and charming vibe. The breakfast was amazing."
United States
Jaramee
The price is £93
includes taxes & fees
7 May - 8 May
Sweetwater Branch Inn

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (502 reviews)
"Breakfast awesome Parking great Staff awesome "
United States
Bryan
The price is £77
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites Alachua I-75

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (605 reviews)
"room was clean and the air conditioning worked great would recommend"
United States
david
The price is £54
includes taxes & fees
23 Apr - 24 Apr
Palms Garden Inn

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay, nice area"
United States
Jennifer
The price is £86
includes taxes & fees
10 May - 11 May
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Best Western Gateway Grand

Best Western Gateway Grand
3.0 star property
Gainesville
8.6 out of 10, Excellent, (1,451 reviews)
"Great location next to I-75 Large rooms great facilities Good breakfast Personnel friendly and knowledgeable "
United States
Michael
The price is £74
includes taxes & fees
10 May - 11 May
Best Western Gateway Grand

SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,000 reviews)
"Hotel was great, friendly staff. "
United States
AnaMaria
The price is £99
includes taxes & fees
23 Apr - 24 Apr
SpringHill Suites by Marriott Gainesville

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.6 out of 10, Excellent, (1,888 reviews)
"Overall a great stay ! "
United States
Angi
The price is £64
includes taxes & fees
6 May - 7 May
HOM Hotel Gainesville, SureStay Collection by Best Western

Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
3.0 star property
Downtown Gainesville
9.2 out of 10, Wonderful, (1,155 reviews)
"Lovely hotel!"
United States
Jennifer
The price is £116
includes taxes & fees
26 Apr - 27 Apr
Hyatt Place Gainesville Downtown

Hampton Inn Gainesville

Hampton Inn Gainesville
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,002 reviews)
"Love this hotel and the staff. "
United States
Tamara
The price is £79
includes taxes & fees
20 May - 21 May
Hampton Inn Gainesville

Travelodge by Wyndham Gainesville

Travelodge by Wyndham Gainesville
2.5 star property
Gainesville
7.4 out of 10, Good, (212 reviews)
"We had good staying in this hotel, it is very comfortable and clean."
United States
Alexander
The price is £46
includes taxes & fees
17 May - 18 May
Travelodge by Wyndham Gainesville

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.6 out of 10, Good, (1,011 reviews)
"Great place all around"
United States
Cadarius
The price is £43
includes taxes & fees
26 Apr - 27 Apr
Super 8 by Wyndham Gainesville I-75 Hospital University Area

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville
2.5 star property
Gainesville
7.4 out of 10, Good, (1,275 reviews)
"Clean room, staf, location and price"
United States
Eduardo R
The price is £51
includes taxes & fees
23 Apr - 24 Apr
Red Roof Inn PLUS+ Gainesville

Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,000 reviews)
"Beautiful hotel very clean people was very nice the breakfast was great "
United States
Janeth
The price is £99
includes taxes & fees
10 May - 11 May
Fairfield Inn & Suites by Marriott Gainesville I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Fe Hotel Reviews

More cheap stays in Santa Fe

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 18.6 mi (29.9 km) from the heart of Santa Fe, Country Inn & Suites by Radisson, Gainesville, FL is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are HOM Hotel Gainesville, SureStay Collection by Best Western and DoubleTree by Hilton Gainesville. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best holiday rentals that Santa Fe has to offer?
Family-Friendly Gainesville Home - Walk to UF - Pool + Sleeps 16: This holiday home rental outside of Santa Fe offers an outdoor pool, a fireplace and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. It offers a balcony, a garden and a selection of games so that you can immerse yourself in your holiday. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
What is staying in Santa Fe like?
Travellers to Santa Fe will find plenty to explore and enjoy. There are 775 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.
What is there to see in Santa Fe?
Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park and Camp Kulaqua Conservation Easement. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.
What's the weather like in Santa Fe?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.

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