Title: The 10 Best 5 Star Hotels in Gainesville - 2026 Updated Prices | Expedia.co.uk [Gainesville Travel Guide](https://expedia.co.uk/Gainesville.dx6048189)[Hotels in Gainesville](https://expedia.co.uk/Gainesville-Hotels.d6048189.Travel-Guide-Hotels)[Holiday Rentals in Gainesville](https://expedia.co.uk/Gainesville-Holiday-Rentals.d6048189.Travel-Guide-HolidayRentals)[Flights to Gainesville](https://expedia.co.uk/Cheap-Flights-To-Gainesville.d6048189.Travel-Guide-Flights)[Things to do in Gainesville](https://expedia.co.uk/Things-To-Do-In-Gainesville.d6048189.Travel-Guide-Activities)[Gainesville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Gainesville.d6048189.Car-Hire-Guide)[Gainesville Holidays](https://expedia.co.uk/Gainesville.d6048189.Holidays-City-Breaks) ![Gainesville which includes interior views](https://images.trvl-media.com/place/6048189/2fd588c5-630b-40be-bcf7-489b9c01f85d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Gainesville # Compare and book 5 Star hotels in Gainesville, Florida - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Gainesville 5 Star Hotels Tonight [21 Dec - 22 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2025-12-21&endDate=2025-12-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Dec - 23 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2025-12-22&endDate=2025-12-23&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2026-01-02&endDate=2026-01-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gainesville-Hotels.s50-0-d6048189.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gainesville-Hotels.s50-0-d6048189.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Gainesville. ![DoubleTree by Hilton Gainesville](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### DoubleTree by Hilton Gainesville 3726 Sw 40th Blvd Gainesville FL £68 28 Dec - 29 Dec includes taxes & fees 7.6/10 Good! (1,001 reviews) [](https://expedia.co.uk/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![ Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/83b7eb2e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar 2548 SW 13th St Gainesville FL £190 22 Dec - 23 Dec includes taxes & fees 8.2/10 Very Good! (8 reviews) [](https://expedia.co.uk/Gainesville-Hotels-The-Scholar.h112021506.Hotel-Information) ![Quiet Convenient and Modern Haven](https://images.trvl-media.com/lodging/91000000/90050000/90049500/90049490/b9ee7a03_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quiet Convenient and Modern Haven 3803 SW 28th Terrace Gainesville FL [Get rates](https://expedia.co.uk/Hotel-Search?startDate=04%2F01%2F2026&endDate=05%2F01%2F2026&selected=90049490&PinnedHotelID=90049490&HadPinnedHotel=true®ionId=6048189) [](https://expedia.co.uk/Gainesville-Hotels-Quiet-Convenient-And-Modern-Haven.h90049490.Hotel-Information) Still don't see what you're looking for? [See all properties in Gainesville.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=22%2F12%2F2025&endDate=23%2F12%2F2025®ionId=6048189&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=22%2F12%2F2025&endDate=23%2F12%2F2025®ionId=6048189&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=22%2F12%2F2025&endDate=23%2F12%2F2025®ionId=6048189&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=22%2F12%2F2025&endDate=23%2F12%2F2025®ionId=6048189&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=22%2F12%2F2025&endDate=23%2F12%2F2025®ionId=6048189&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=22%2F12%2F2025&endDate=23%2F12%2F2025®ionId=6048189&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Gainesville and related destinations - Gainesville - Lubbock - Cedar Rapids - Iowa City - Topeka - Athens Home to the Florida Gators, this college town buzzes with energy at The Swamp during football season. Explore the natural springs at Paynes Prairie or stroll through the butterfly-filled exhibits at the Florida Museum of Natural History. [See all hotels in Gainesville](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-04&endDate=2026-01-05&adults=2®ionId=6048189) ![Gainesville which includes interior views](https://images.trvl-media.com/place/6048189/2fd588c5-630b-40be-bcf7-489b9c01f85d.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Visit Gainesville ## Top Gainesville Hotel Reviews ## Find out more about Gainesville ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Gainesville? > - Search for the lowest price per night from £68 ### What makes a hotel 5 stars in Gainesville? ### Are there any 5-star all-inclusive resorts in Gainesville? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [1 Star Hotels in Fort George Island Cultural State Park ](https://www.expedia.co.uk/1Star-Fort-George-Island-Cultural-State-Park-Hotels.s10-0-d553248621561766886.Travel-Guide-Filter-Hotels) - [1 Star Hotels in Northwest Orlando ](https://www.expedia.co.uk/1Star-Northwest-Orlando-Hotels.s10-0-d553248635976480707.Travel-Guide-Filter-Hotels) - 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