Title: The 10 Best 5 Star Hotels in Gainesville - 2025 Updated Prices | Expedia.co.uk [Gainesville Travel Guide](https://expedia.co.uk/Gainesville.dx6048189)[Hotels in Gainesville](https://expedia.co.uk/Gainesville-Hotels.d6048189.Travel-Guide-Hotels)[Holiday Rentals in Gainesville](https://expedia.co.uk/Gainesville-Holiday-Rentals.d6048189.Travel-Guide-HolidayRentals)[Flights to Gainesville](https://expedia.co.uk/Cheap-Flights-To-Gainesville.d6048189.Travel-Guide-Flights)[Things to do in Gainesville](https://expedia.co.uk/Things-To-Do-In-Gainesville.d6048189.Travel-Guide-Activities)[Gainesville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Gainesville.d6048189.Car-Hire-Guide)[Gainesville Holidays](https://expedia.co.uk/Gainesville.d6048189.Holidays-City-Breaks) ![Gainesville which includes interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/61000/61917-Gainesville.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Gainesville, Florida - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Gainesville 5 Star Hotels Tonight [3 Nov - 4 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2025-11-03&endDate=2025-11-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Nov - 5 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2025-11-04&endDate=2025-11-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2025-11-07&endDate=2025-11-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6048189&startDate=2025-11-14&endDate=2025-11-16&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Gainesville 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gainesville-Hotels.s50-0-d6048189.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gainesville-Hotels.s50-0-d6048189.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Gainesville. ![DoubleTree by Hilton Gainesville](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### DoubleTree by Hilton Gainesville 3726 Sw 40th Blvd, Gainesville, FL £76 9 Nov - 10 Nov includes taxes & fees 7.6/10 Good! (1,007 reviews) [](https://expedia.co.uk/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information) ![ Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/83b7eb2e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar 2548 SW 13th St, Gainesville, FL £199 4 Nov - 5 Nov includes taxes & fees 8.2/10 Very Good! (7 reviews) [](https://expedia.co.uk/Gainesville-Hotels-The-Scholar.h112021506.Hotel-Information) ![Quiet Convenient and Modern Haven](https://images.trvl-media.com/lodging/91000000/90050000/90049500/90049490/b9ee7a03_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quiet Convenient and Modern Haven 3803 SW 28th Terrace, Gainesville, FL [Get rates](https://expedia.co.uk/Hotel-Search?startDate=17%2F11%2F2025&endDate=18%2F11%2F2025&selected=90049490&PinnedHotelID=90049490&HadPinnedHotel=true®ionId=6048189) [](https://expedia.co.uk/Gainesville-Hotels-Quiet-Convenient-And-Modern-Haven.h90049490.Hotel-Information) Still don't see what you're looking for? [See all properties in Gainesville.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=04%2F11%2F2025&endDate=05%2F11%2F2025®ionId=6048189&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=04%2F11%2F2025&endDate=05%2F11%2F2025®ionId=6048189&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=04%2F11%2F2025&endDate=05%2F11%2F2025®ionId=6048189&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=04%2F11%2F2025&endDate=05%2F11%2F2025®ionId=6048189&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=04%2F11%2F2025&endDate=05%2F11%2F2025®ionId=6048189&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=04%2F11%2F2025&endDate=05%2F11%2F2025®ionId=6048189&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Gainesville and related destinations - Gainesville - Lubbock - Cedar Rapids - Iowa City - Topeka - Athens Home to the Florida Gators, this college town buzzes with energy at The Swamp during football season. Explore the natural springs at Paynes Prairie or stroll through the butterfly-filled exhibits at the Florida Museum of Natural History. [See all hotels in Gainesville](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18&adults=2®ionId=6048189) ![Gainesville which includes interior views](https://images.trvl-media.com/place/6048189/2fd588c5-630b-40be-bcf7-489b9c01f85d.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Visit Gainesville ## Top Gainesville Hotel Reviews ## Find out more about Gainesville ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Gainesville? > The amount you pay for a 5-star hotel in Gainesville depends on things such as when you plan to travel and the length of your escape. An insider tip for scoring the best deal? Use our pricing filters to compare all of the available accommodation for your selected dates. > > > > - Search for the lowest price per night from £76 ### What makes a hotel 5 stars in Gainesville? > Outstanding guest service is at the heart of every 5-star hotel in Gainesville. From the moment you arrive, staff cater to your every whim, whether recommending activities or providing in-room beauty treatments. Also, hotels must feature top-rate amenities to be considered for a 5-star rating. These can include deluxe baths, on-site spa facilities, swimming pools, gourmet kitchens and knowledgeable concierge. ### Are there any 5-star all-inclusive resorts in Gainesville? > Use our filter tool to find a luxury escape in Gainesville where everything you need is included. From there, narrow down your results for accommodation that have a 5-star rating and are deemed "All inclusive." The most important thing on the itinerary at these stays? 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